JPS6135188B2 - - Google Patents

Info

Publication number
JPS6135188B2
JPS6135188B2 JP56117569A JP11756981A JPS6135188B2 JP S6135188 B2 JPS6135188 B2 JP S6135188B2 JP 56117569 A JP56117569 A JP 56117569A JP 11756981 A JP11756981 A JP 11756981A JP S6135188 B2 JPS6135188 B2 JP S6135188B2
Authority
JP
Japan
Prior art keywords
chloro
dione
oxazolidine
reference example
ethyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
JP56117569A
Other languages
English (en)
Japanese (ja)
Other versions
JPS5758676A (en
Inventor
Kooren Shunuaa Rodonii
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Inc
Original Assignee
Pfizer Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Inc filed Critical Pfizer Inc
Publication of JPS5758676A publication Critical patent/JPS5758676A/ja
Publication of JPS6135188B2 publication Critical patent/JPS6135188B2/ja
Granted legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20Oxygen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/51Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition
    • C07C45/511Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition involving transformation of singly bound oxygen functional groups to >C = O groups
    • C07C45/513Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition involving transformation of singly bound oxygen functional groups to >C = O groups the singly bound functional group being an etherified hydroxyl group
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/18Halogen atoms or nitro radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • General Chemical & Material Sciences (AREA)
  • Emergency Medicine (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Endocrinology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
JP56117569A 1980-07-28 1981-07-27 Blood sugar lowering 5-substituted oxazolidine-2,4-dione Granted JPS5758676A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US17320680A 1980-07-28 1980-07-28

Publications (2)

Publication Number Publication Date
JPS5758676A JPS5758676A (en) 1982-04-08
JPS6135188B2 true JPS6135188B2 (de) 1986-08-12

Family

ID=22630977

Family Applications (1)

Application Number Title Priority Date Filing Date
JP56117569A Granted JPS5758676A (en) 1980-07-28 1981-07-27 Blood sugar lowering 5-substituted oxazolidine-2,4-dione

Country Status (4)

Country Link
JP (1) JPS5758676A (de)
BE (2) BE889758A (de)
GT (2) GT198170555A (de)
ZA (2) ZA815126B (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4430337A (en) * 1982-06-23 1984-02-07 Pfizer Inc. Alicyclic substituted oxazolidine-2,4-diones having hypoglycemic activity
US4617312A (en) * 1983-01-17 1986-10-14 Pfizer Inc. Aldose reductase inhibiting 5-(2-alkoxyphenyl) thiazolidinediones

Also Published As

Publication number Publication date
ZA815133B (en) 1982-07-28
ZA815126B (en) 1983-02-23
GT198170555A (es) 1983-01-12
GT198170554A (es) 1983-01-12
JPS5758676A (en) 1982-04-08
BE889757A (fr) 1982-01-27
BE889758A (fr) 1982-01-27

Similar Documents

Publication Publication Date Title
KR850000381B1 (ko) 5-치환된 옥사졸리딘-2,-4디온의 제조방법
JP3906935B2 (ja) N−置換ジオキソチアゾリジルベンズアミド誘導体及びその製造法
US4342771A (en) Hypoglycemic 5-substituted oxazolidine-2,4-diones
WO1991001306A1 (fr) Derive oxoindole
JP2596446B2 (ja) Z―1―(p―β―ジメチルアミノエトキシフェニル)―1―(p―ヒドロキシフェニル)―2―フェニル―ブド―1―エンの安定な溶媒付加物、その製造法及びそれを含有する薬剤
HU179746B (en) Process for producing new spiro-oxasolidines
BE898278A (fr) Benzoxazines antipsychotiques.
KR900007313B1 (ko) 혈당강하제인 옥사졸리딘-2-온 유도체
JPS6230993B2 (de)
FR2662442A1 (fr) Trifluoromethylphenyltetrahydropyridines n-substituees procede pour leur preparation, intermediaires du procede et compositions pharmaceutiques les contenant.
JPS6135188B2 (de)
JPS5982378A (ja) 3―アミノプロポキシフェニル誘導体およびその製法ならび用途
JP4010377B2 (ja) N−ベンジルジオキソチアゾリジルベンズアミド誘導体及びその製造法
EP0005091B1 (de) Monosubstituierte Piperazine, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Präparate
JPH11507331A (ja) 4,4−(二置換)シクロヘキサン−1−オール類モノマーおよび関連化合物
US4448971A (en) Hypoglycemic 5-phenyl-substituted oxazolidine-2,4-diones
US4407811A (en) Hypoglycemic 5-substituted oxazolidine-2,4-diones
JPH0329073B2 (de)
US4399296A (en) Hypoglycemic 5-substituted oxazolidine-2,4-diones
NZ209273A (en) Alkyl aryl(hydroxy)methanecarboximidates
JPH0676325B2 (ja) オキサジアジン誘導体を有効成分として含有する抗血栓剤
KR850000389B1 (ko) 5-치환된 옥사졸리딘-2, 4-디온의 제조방법
JPH05194222A (ja) 血糖降下剤
JPH10511658A (ja) 4,4−(二置換)シクロヘキサン−1−オール単量体および関連する化合物
JPS638947B2 (de)