JPS6134426B2 - - Google Patents

Info

Publication number
JPS6134426B2
JPS6134426B2 JP52059295A JP5929577A JPS6134426B2 JP S6134426 B2 JPS6134426 B2 JP S6134426B2 JP 52059295 A JP52059295 A JP 52059295A JP 5929577 A JP5929577 A JP 5929577A JP S6134426 B2 JPS6134426 B2 JP S6134426B2
Authority
JP
Japan
Prior art keywords
cis
trans
methyl
compounds
hexahydro
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
JP52059295A
Other languages
English (en)
Japanese (ja)
Other versions
JPS532465A (en
Inventor
Yakobu Fuan Deru Burugu Uiremu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Akzo NV
Original Assignee
Akzo NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo NV filed Critical Akzo NV
Publication of JPS532465A publication Critical patent/JPS532465A/ja
Publication of JPS6134426B2 publication Critical patent/JPS6134426B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/58—[b]- or [c]-condensed
    • C07D209/70—[b]- or [c]-condensed containing carbocyclic rings other than six-membered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/04—Ortho- or peri-condensed ring systems
    • C07D221/18—Ring systems of four or more rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Indole Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
JP5929577A 1976-05-24 1977-05-20 Novel tetracyclic derivative* its preparation and formulations containing same Granted JPS532465A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NL7605526A NL7605526A (nl) 1976-05-24 1976-05-24 Nieuwe tetracyclische derivaten.

Publications (2)

Publication Number Publication Date
JPS532465A JPS532465A (en) 1978-01-11
JPS6134426B2 true JPS6134426B2 (en:Method) 1986-08-07

Family

ID=19826245

Family Applications (2)

Application Number Title Priority Date Filing Date
JP5929577A Granted JPS532465A (en) 1976-05-24 1977-05-20 Novel tetracyclic derivative* its preparation and formulations containing same
JP61007790A Granted JPS61178965A (ja) 1976-05-24 1986-01-17 新規な四環式誘導体

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP61007790A Granted JPS61178965A (ja) 1976-05-24 1986-01-17 新規な四環式誘導体

Country Status (18)

Country Link
US (1) US4145434A (en:Method)
JP (2) JPS532465A (en:Method)
AU (1) AU509073B2 (en:Method)
BE (1) BE854915A (en:Method)
CA (1) CA1122976A (en:Method)
CH (2) CH633536A5 (en:Method)
DE (2) DE2723209A1 (en:Method)
DK (1) DK157868C (en:Method)
ES (3) ES459024A1 (en:Method)
FI (1) FI65238C (en:Method)
FR (1) FR2352800A1 (en:Method)
GB (1) GB1567862A (en:Method)
HU (1) HU173795B (en:Method)
IE (1) IE45419B1 (en:Method)
LU (1) LU77387A1 (en:Method)
NL (1) NL7605526A (en:Method)
SE (1) SE436202B (en:Method)
ZA (1) ZA772752B (en:Method)

Families Citing this family (87)

* Cited by examiner, † Cited by third party
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EP0007450A1 (de) * 1978-07-07 1980-02-06 Ciba-Geigy Ag Azatetracyclische Carbonitrile, ihre Herstellung, pharmazeutische Präparate, die diese enthalten und deren Verwendung
ATE9159T1 (de) * 1979-12-10 1984-09-15 Ciba-Geigy Ag Azatetracyclische carbonitrile.
FR2504140A1 (fr) * 1981-04-16 1982-10-22 Centre Nat Rech Scient Nouveaux derives tetracycliques de la dibenzazepine, leur procede de preparation et les compositions pharmaceutiques en renfermant
CA1202970A (en) * 1982-05-18 1986-04-08 Eugene J. Trybulski Benzazepine derivatives
JPS62101941U (en:Method) * 1985-12-16 1987-06-29
IE62754B1 (en) * 1988-08-26 1995-02-22 Akzo Nv Tetracyclic antidepressants
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HRP20030956A2 (en) * 2003-11-21 2005-08-31 Pliva-Istra�iva�ki institut d.o.o. USE OF 1,2-DIAZA-DIBENZO[e,h]AZULENES FOR THE MANU
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JP2007537232A (ja) * 2004-05-11 2007-12-20 ファイザー・プロダクツ・インク 非定型抗精神病薬と５−ｈｔ１ｂ受容体拮抗薬の組合せ
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PL3338768T3 (pl) 2016-12-20 2020-05-18 Lts Lohmann Therapie-Systeme Ag Transdermalny system terapeutyczny zawierający asenapinę
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CN112830931A (zh) 2019-08-13 2021-05-25 浙江奥翔药业股份有限公司 制备阿塞那平的方法
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Also Published As

Publication number Publication date
GB1567862A (en) 1980-05-21
ZA772752B (en) 1978-04-26
DK227477A (da) 1977-11-25
FI65238B (fi) 1983-12-30
FR2352800A1 (fr) 1977-12-23
IE45419L (en) 1977-11-24
CH633536A5 (de) 1982-12-15
NL7605526A (nl) 1977-11-28
ES470408A1 (es) 1979-01-01
FR2352800B1 (en:Method) 1980-02-01
HU173795B (hu) 1979-08-28
SE7705957L (sv) 1977-11-25
IE45419B1 (en) 1982-08-25
DK157868C (da) 1990-07-30
DK157868B (da) 1990-02-26
DE2723209A1 (de) 1977-12-15
AU509073B2 (en) 1980-04-17
JPS6238348B2 (en:Method) 1987-08-17
SE436202B (sv) 1984-11-19
JPS532465A (en) 1978-01-11
JPS61178965A (ja) 1986-08-11
CA1122976A (en) 1982-05-04
DE2760372C2 (en:Method) 1991-05-29
CH637382A5 (de) 1983-07-29
BE854915A (fr) 1977-11-23
FI771635A7 (en:Method) 1977-11-25
ES470407A1 (es) 1979-01-01
ES459024A1 (es) 1978-11-01
FI65238C (fi) 1984-04-10
US4145434A (en) 1979-03-20
LU77387A1 (en:Method) 1977-08-29
AU2533177A (en) 1978-11-23

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