JPS61264254A - ポリエチレンイミン結合クロマトグラフ充填剤 - Google Patents

ポリエチレンイミン結合クロマトグラフ充填剤

Info

Publication number
JPS61264254A
JPS61264254A JP61090202A JP9020286A JPS61264254A JP S61264254 A JPS61264254 A JP S61264254A JP 61090202 A JP61090202 A JP 61090202A JP 9020286 A JP9020286 A JP 9020286A JP S61264254 A JPS61264254 A JP S61264254A
Authority
JP
Japan
Prior art keywords
silica gel
microns
average
average particle
particle size
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP61090202A
Other languages
English (en)
Japanese (ja)
Other versions
JPH0370182B2 (enExample
Inventor
ハグ　イー．ラムスデン
マイケル　ヘンリー
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Avantor Performance Materials LLC
Original Assignee
JT Baker Chemical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by JT Baker Chemical Co filed Critical JT Baker Chemical Co
Publication of JPS61264254A publication Critical patent/JPS61264254A/ja
Publication of JPH0370182B2 publication Critical patent/JPH0370182B2/ja
Granted legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/22—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising organic material
    • B01J20/26—Synthetic macromolecular compounds
    • B01J20/262—Synthetic macromolecular compounds obtained otherwise than by reactions only involving carbon to carbon unsaturated bonds, e.g. obtained by polycondensation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/02—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising inorganic material
    • B01J20/10—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising inorganic material comprising silica or silicate
    • B01J20/103—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising inorganic material comprising silica or silicate comprising silica
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/28—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties
    • B01J20/28002—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties characterised by their physical properties
    • B01J20/28004—Sorbent size or size distribution, e.g. particle size
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/28—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties
    • B01J20/28054—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties characterised by their surface properties or porosity
    • B01J20/28078—Pore diameter
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/281—Sorbents specially adapted for preparative, analytical or investigative chromatography
    • B01J20/286—Phases chemically bonded to a substrate, e.g. to silica or to polymers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/281—Sorbents specially adapted for preparative, analytical or investigative chromatography
    • B01J20/291—Gel sorbents
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/3092—Packing of a container, e.g. packing a cartridge or column
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3202—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the carrier, support or substrate used for impregnation or coating
    • B01J20/3204—Inorganic carriers, supports or substrates
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3214—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the method for obtaining this coating or impregnating
    • B01J20/3217—Resulting in a chemical bond between the coating or impregnating layer and the carrier, support or substrate, e.g. a covalent bond
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3214—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the method for obtaining this coating or impregnating
    • B01J20/3217—Resulting in a chemical bond between the coating or impregnating layer and the carrier, support or substrate, e.g. a covalent bond
    • B01J20/3219—Resulting in a chemical bond between the coating or impregnating layer and the carrier, support or substrate, e.g. a covalent bond involving a particular spacer or linking group, e.g. for attaching an active group
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
    • B01J20/3242—Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
    • B01J20/3244—Non-macromolecular compounds
    • B01J20/3246—Non-macromolecular compounds having a well defined chemical structure
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
    • B01J20/3242—Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
    • B01J20/3268—Macromolecular compounds
    • B01J20/3272—Polymers obtained by reactions otherwise than involving only carbon to carbon unsaturated bonds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/12—Organo silicon halides
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2220/00—Aspects relating to sorbent materials
    • B01J2220/50—Aspects relating to the use of sorbent or filter aid materials
    • B01J2220/54—Sorbents specially adapted for analytical or investigative chromatography
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2220/00—Aspects relating to sorbent materials
    • B01J2220/50—Aspects relating to the use of sorbent or filter aid materials
    • B01J2220/58—Use in a single column

Landscapes

  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Inorganic Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
JP61090202A 1985-04-22 1986-04-21 ポリエチレンイミン結合クロマトグラフ充填剤 Granted JPS61264254A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US725807 1985-04-22
US06/725,807 US4551245A (en) 1985-04-22 1985-04-22 Acylated polyethylenimine bound chromatographic packing

Publications (2)

Publication Number Publication Date
JPS61264254A true JPS61264254A (ja) 1986-11-22
JPH0370182B2 JPH0370182B2 (enExample) 1991-11-06

Family

ID=24916047

Family Applications (1)

Application Number Title Priority Date Filing Date
JP61090202A Granted JPS61264254A (ja) 1985-04-22 1986-04-21 ポリエチレンイミン結合クロマトグラフ充填剤

Country Status (13)

Country Link
US (1) US4551245A (enExample)
EP (1) EP0199222B1 (enExample)
JP (1) JPS61264254A (enExample)
KR (1) KR890002847B1 (enExample)
AT (1) ATE46281T1 (enExample)
AU (1) AU576144B2 (enExample)
CA (1) CA1256418A (enExample)
DE (1) DE3665547D1 (enExample)
DK (1) DK162020C (enExample)
IE (1) IE59080B1 (enExample)
IL (1) IL78226A (enExample)
NZ (1) NZ215556A (enExample)
ZA (1) ZA862052B (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6276457A (ja) * 1985-09-30 1987-04-08 Shimadzu Corp 液体クロマトグラフイ用充填剤
JPH0326961A (ja) * 1989-06-20 1991-02-05 J T Baker Inc アフィニティークロマトグラフィー用のポリエチレンイミンマトリックス

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6177760A (ja) * 1984-09-26 1986-04-21 Daicel Chem Ind Ltd 分離剤
US4650784A (en) * 1986-02-20 1987-03-17 J. T. Baker Chemical Company Bonded phase of silica for solid phase extraction
US4680121A (en) * 1986-02-20 1987-07-14 J. T. Baker Chemical Company Bonded phase of silica for solid phase extraction
US4721573A (en) * 1986-03-06 1988-01-26 J. T. Baker Chemical Company Use of sulfonic derivatives of acylated polyethyleneimine bonded phase silica products
US4661248A (en) * 1986-03-06 1987-04-28 J. T. Baker Chemical Company Sulfonic derivatives of acylated polyethyleneimine bonded phase silica products
US5066395A (en) * 1986-03-06 1991-11-19 J. T. Baker Inc. N-acylated derivatives of polyethyleneimine bonded phase silica products
US4920152A (en) * 1986-05-13 1990-04-24 Purdue Research Foundation Reversed-phase packing material and method
US4804686A (en) * 1986-05-13 1989-02-14 Purdue Research Foundation Cation-exchange support materials and method
SE464687B (sv) * 1987-11-10 1991-06-03 Biocarb Ab Foerfarande foer framstaellning av en gelprodukt
DE3811042A1 (de) * 1988-03-31 1989-10-19 Merck Patent Gmbh Ionenaustauscher
EP0386926A3 (en) * 1989-03-02 1991-12-18 Supelco, Inc. Silica gel supports suitable for chromatographic separations
DE59406939D1 (en) * 1993-07-16 1998-10-22 Merck Patent Gmbh Trennmaterialien für die hydrophobe chromatographie
DE4333674A1 (de) * 1993-10-02 1995-04-06 Merck Patent Gmbh Nukleotidhaltiges Sorbens für die Affinitätschromatographie
DE4333821A1 (de) * 1993-10-04 1995-04-06 Merck Patent Gmbh Ionenaustauscher
DE4334353A1 (de) * 1993-10-08 1995-04-13 Merck Patent Gmbh Verfahren und Träger für die Gelpermeationschromatographie
US5695882A (en) * 1995-08-17 1997-12-09 The University Of Montana System for extracting soluble heavy metals from liquid solutions
US5869152A (en) * 1996-03-01 1999-02-09 The Research Foundation Of State University Of New York Silica materials
EP1301571A2 (en) 2000-07-17 2003-04-16 President And Fellows of Harvard College Surfaces that resist the adsorption of biological species
DE10120821A1 (de) * 2001-04-27 2002-10-31 Sachtleben Chemie Gmbh Mit Polyalken beschichtete, poröse Füllstoffe
US6802966B2 (en) 2001-08-14 2004-10-12 W. R. Grace & Co. Conn. Solid compositions for selective adsorption from complex mixtures
US6987079B2 (en) 2001-08-14 2006-01-17 W.R. Grace & Co.-Conn. Supported catalyst systems
US6923895B2 (en) * 2002-09-09 2005-08-02 Beckman Coulter, Inc. Coated capillary electrophoresis tubes and system
MY144940A (en) * 2005-01-25 2011-11-30 Avantor Performance Mat Inc Chromatographic media
TW201138974A (en) 2010-04-05 2011-11-16 Avantor Performance Mat Inc Process for trypsin and chymotrypsin purification utilizing hydrophobic interaction chromatography
CN103959057A (zh) * 2011-05-03 2014-07-30 安万托特性材料股份有限公司 用于蛋白质纯化的基于烯丙胺及其衍生物的新型色谱介质
CN104968403A (zh) 2012-09-17 2015-10-07 格雷斯公司 色谱介质和装置
ES2929099T3 (es) 2014-05-02 2022-11-24 Grace W R & Co Material de soporte funcionalizado y métodos de fabricación y uso de material de soporte funcionalizado
JP2016006410A (ja) * 2014-05-27 2016-01-14 Jnc株式会社 クロマトグラフィー担体およびそれを用いたタンパク質精製方法
PL3302784T3 (pl) 2015-06-05 2022-01-17 W.R. Grace & Co.-Conn. Adsorbentowe środki klarujące do bioprzetwarzania oraz sposoby ich wytwarzania i stosowania
EP3845306A4 (en) * 2018-08-31 2022-05-18 Showa Denko K.K. PACKING MATERIAL FOR ION CHROMATOGRAPHY AND MANUFACTURING METHOD THEREOF
WO2021163910A1 (en) * 2020-02-19 2021-08-26 Bio-Rad Laboratories, Inc. Method of preparing polymer-filled chromatography resin

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3722181A (en) * 1970-05-22 1973-03-27 Du Pont Chromatographic packing with chemically bonded organic stationary phases
DE2236862C2 (de) * 1972-07-27 1974-09-05 Istvan Prof. Dr. 6600 Saarbruecken Halasz Sorptionsmittel für die Chromatographie
US4212905A (en) * 1976-06-30 1980-07-15 Board of Reagents, for and on behalf of the University of Florida Method of coating supports using addition copolymers of aminimides
US4290892A (en) * 1978-10-23 1981-09-22 Varian Associates, Inc. Anion exchange chromatographic separation of polyfunctional compounds
US4245005A (en) * 1979-02-28 1981-01-13 Purdue Research Foundation Pellicular coated support and method
DE3271828D1 (en) * 1981-04-27 1986-07-31 Health Lab Service Board High pressure liquid affinity chromatography
US4469630A (en) * 1983-11-25 1984-09-04 J. T. Baker Chemical Co. Purification of monoclonal antibodies

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6276457A (ja) * 1985-09-30 1987-04-08 Shimadzu Corp 液体クロマトグラフイ用充填剤
JPH0326961A (ja) * 1989-06-20 1991-02-05 J T Baker Inc アフィニティークロマトグラフィー用のポリエチレンイミンマトリックス

Also Published As

Publication number Publication date
IL78226A0 (en) 1986-07-31
KR890002847B1 (ko) 1989-08-05
DK181886D0 (da) 1986-04-21
US4551245A (en) 1985-11-05
NZ215556A (en) 1989-04-26
DE3665547D1 (en) 1989-10-19
KR860008190A (ko) 1986-11-12
AU576144B2 (en) 1988-08-11
AU5504586A (en) 1986-10-30
ZA862052B (en) 1987-02-25
EP0199222B1 (en) 1989-09-13
JPH0370182B2 (enExample) 1991-11-06
IE59080B1 (en) 1994-01-12
EP0199222A2 (en) 1986-10-29
EP0199222A3 (en) 1987-05-06
CA1256418A (en) 1989-06-27
DK162020B (da) 1991-09-09
IL78226A (en) 1989-10-31
ATE46281T1 (de) 1989-09-15
DK181886A (da) 1986-10-23
DK162020C (da) 1992-02-10
IE860686L (en) 1986-10-22

Similar Documents

Publication Publication Date Title
JPS61264254A (ja) ポリエチレンイミン結合クロマトグラフ充填剤
EP0143423B1 (en) Polyethylenimide bound chromatographic packing
CA1303594C (en) Optically active adsorbents
US4767670A (en) Chromatographic supports for separation of oligonucleotides
US4298500A (en) Mixed phase chromatographic compositions
US4661248A (en) Sulfonic derivatives of acylated polyethyleneimine bonded phase silica products
US5104547A (en) Separating materials for chromatography comprising cyclodextrin chemically bonded to a support via a carbamic acid group
EP0656333A1 (en) Optical isomer separating agent and process for producing the same
US6217769B1 (en) Separating agent for optical isomers and process for producing the same
CN111013557B (zh) 一种疏水层析介质及其制备方法和应用
EP0299793A2 (en) Packing materials for analysing enantiomer mixtures by liquid chromatography
JPS60252489A (ja) 液体クロマトグラフイー用化学結合型充填剤及びその製法
US4627919A (en) Resolving agent
US5066395A (en) N-acylated derivatives of polyethyleneimine bonded phase silica products
EP2830755A1 (en) Doped materials for reverse phase chromatography
US6551515B1 (en) Particulate soild supports functionalized with EGTA ligands
JPH038511B2 (enExample)
JPS62278450A (ja) 光学分割剤
JPS6110771A (ja) 分離剤
CN117339580A (zh) 螯合载体、其制备方法及应用
JPS63218249A (ja) 光学分割用充填剤およびその製法
JPH0193544A (ja) 光学分割剤
JP2001163897A (ja) ペプチドおよび該ペプチドを固定化した吸着材

Legal Events

Date Code Title Description
R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

EXPY Cancellation because of completion of term