JPS6058908B2 - システイン誘導体 - Google Patents

システイン誘導体

Info

Publication number
JPS6058908B2
JPS6058908B2 JP53125539A JP12553978A JPS6058908B2 JP S6058908 B2 JPS6058908 B2 JP S6058908B2 JP 53125539 A JP53125539 A JP 53125539A JP 12553978 A JP12553978 A JP 12553978A JP S6058908 B2 JPS6058908 B2 JP S6058908B2
Authority
JP
Japan
Prior art keywords
cysteine
ethyl acetate
benzoyl
mol
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
JP53125539A
Other languages
English (en)
Japanese (ja)
Other versions
JPS5551054A (en
Inventor
順一 岩尾
正雪 大矢
剛久 千葉
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Santen Pharmaceutical Co Ltd
Original Assignee
Santen Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Santen Pharmaceutical Co Ltd filed Critical Santen Pharmaceutical Co Ltd
Priority to JP53125539A priority Critical patent/JPS6058908B2/ja
Priority to SE7908168A priority patent/SE446981B/sv
Priority to US06/082,331 priority patent/US4255446A/en
Priority to GB7934618A priority patent/GB2032433B/en
Priority to IT26317/79A priority patent/IT1193842B/it
Priority to FR7925307A priority patent/FR2439774A1/fr
Priority to DE19792941288 priority patent/DE2941288A1/de
Publication of JPS5551054A publication Critical patent/JPS5551054A/ja
Publication of JPS6058908B2 publication Critical patent/JPS6058908B2/ja
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
    • C07C323/24—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/25—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
    • C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/60—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton with the carbon atom of at least one of the carboxyl groups bound to nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP53125539A 1978-10-11 1978-10-11 システイン誘導体 Expired JPS6058908B2 (ja)

Priority Applications (7)

Application Number Priority Date Filing Date Title
JP53125539A JPS6058908B2 (ja) 1978-10-11 1978-10-11 システイン誘導体
SE7908168A SE446981B (sv) 1978-10-11 1979-10-02 Cysteinderivat samt farmaceutisk komposition innehallande nemnda cysteinderivat som aktiv komponent
US06/082,331 US4255446A (en) 1978-10-11 1979-10-05 Cysteine derivatives
GB7934618A GB2032433B (en) 1978-10-11 1979-10-05 Cysteine derivatives
IT26317/79A IT1193842B (it) 1978-10-11 1979-10-08 Derivati della cisteina
FR7925307A FR2439774A1 (fr) 1978-10-11 1979-10-11 Nouveaux derives de crysteine utiles notamment comme medicaments pour la suppression des troubles hepatiques et procedes pour leur preparation
DE19792941288 DE2941288A1 (de) 1978-10-11 1979-10-11 Cystein-derivate

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP53125539A JPS6058908B2 (ja) 1978-10-11 1978-10-11 システイン誘導体

Publications (2)

Publication Number Publication Date
JPS5551054A JPS5551054A (en) 1980-04-14
JPS6058908B2 true JPS6058908B2 (ja) 1985-12-23

Family

ID=14912687

Family Applications (1)

Application Number Title Priority Date Filing Date
JP53125539A Expired JPS6058908B2 (ja) 1978-10-11 1978-10-11 システイン誘導体

Country Status (7)

Country Link
US (1) US4255446A (enExample)
JP (1) JPS6058908B2 (enExample)
DE (1) DE2941288A1 (enExample)
FR (1) FR2439774A1 (enExample)
GB (1) GB2032433B (enExample)
IT (1) IT1193842B (enExample)
SE (1) SE446981B (enExample)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5732260A (en) * 1980-08-07 1982-02-20 Meito Sangyo Kk Mercaptofatty acid derivative and its preparation
JPS5756454A (en) * 1980-09-20 1982-04-05 Santen Pharmaceut Co Ltd Disulfide type cysteine derivative
US4434158A (en) 1981-02-11 1984-02-28 Cornell Research Foundation Cysteine delivery system
US4438124A (en) 1981-02-11 1984-03-20 Cornell Research Foundation, Inc. Cysteine delivery system
US4571430A (en) * 1982-11-08 1986-02-18 Medi-Physics, Inc. Homocysteine and homocysteinamide derivatives
DE68904203T4 (de) * 1988-01-25 1993-10-28 Santen Pharma Co Ltd Cysteinderivate.
AT394493B (de) * 1989-05-11 1992-04-10 Homosan Ag Pharmazeutisches praeparat zur behandlung von lebererkrankungen
JP2720217B2 (ja) * 1989-12-05 1998-03-04 参天製薬株式会社 含硫黄アミノ酸誘導体
US6025393A (en) * 1995-09-25 2000-02-15 Santen Pharmaceutical Co., Ltd. Method for treatment of inflammatory intestinal diseases
US5670545A (en) * 1996-02-09 1997-09-23 Board Of Regents Of The University Of Colorado Method for the treatment of ischemic disease and reperfusion injury and the prevention of the adverse effects of reactive oxygen species
KR20030010445A (ko) * 2001-07-25 2003-02-05 건일제약 주식회사 Ｌ-시스테인 유도체의 제조방법

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS535112A (en) * 1976-03-08 1978-01-18 Santen Pharmaceutical Co Ltd New cysteine derivatives
US4053651A (en) * 1976-05-10 1977-10-11 E. R. Squibb & Sons, Inc. Compounds and method for alleviating angiotensin related hypertension

Also Published As

Publication number Publication date
FR2439774A1 (fr) 1980-05-23
JPS5551054A (en) 1980-04-14
GB2032433A (en) 1980-05-08
FR2439774B1 (enExample) 1983-11-10
IT1193842B (it) 1988-08-24
IT7926317A0 (it) 1979-10-08
DE2941288A1 (de) 1980-04-30
US4255446A (en) 1981-03-10
DE2941288C2 (enExample) 1990-05-17
SE7908168L (sv) 1980-04-12
SE446981B (sv) 1986-10-20
GB2032433B (en) 1982-10-27

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