JPS6035263A - 不溶性担体に固定化された免疫活性物質の安定化法及び該物質を構成単位として含む生理活性物質測定用試薬 - Google Patents
不溶性担体に固定化された免疫活性物質の安定化法及び該物質を構成単位として含む生理活性物質測定用試薬Info
- Publication number
- JPS6035263A JPS6035263A JP58144201A JP14420183A JPS6035263A JP S6035263 A JPS6035263 A JP S6035263A JP 58144201 A JP58144201 A JP 58144201A JP 14420183 A JP14420183 A JP 14420183A JP S6035263 A JPS6035263 A JP S6035263A
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- QQONPFPTGQHPMA-UHFFFAOYSA-N propylene Natural products CC=C QQONPFPTGQHPMA-UHFFFAOYSA-N 0.000 description 1
- 125000004805 propylene group Chemical group [H]C([H])([H])C([H])([*:1])C([H])([H])[*:2] 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- HEBKCHPVOIAQTA-ZXFHETKHSA-N ribitol Chemical compound OC[C@H](O)[C@H](O)[C@H](O)CO HEBKCHPVOIAQTA-ZXFHETKHSA-N 0.000 description 1
- 229960004889 salicylic acid Drugs 0.000 description 1
- 229920002050 silicone resin Polymers 0.000 description 1
- 229920002379 silicone rubber Polymers 0.000 description 1
- 239000004945 silicone rubber Substances 0.000 description 1
- 229960004025 sodium salicylate Drugs 0.000 description 1
- 239000007790 solid phase Substances 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 241000894007 species Species 0.000 description 1
- 239000003270 steroid hormone Substances 0.000 description 1
- 239000013076 target substance Substances 0.000 description 1
- 239000012085 test solution Substances 0.000 description 1
- 229940034208 thyroxine Drugs 0.000 description 1
- XUIIKFGFIJCVMT-UHFFFAOYSA-N thyroxine-binding globulin Natural products IC1=CC(CC([NH3+])C([O-])=O)=CC(I)=C1OC1=CC(I)=C(O)C(I)=C1 XUIIKFGFIJCVMT-UHFFFAOYSA-N 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- LENZDBCJOHFCAS-UHFFFAOYSA-N tris Chemical compound OCC(N)(CO)CO LENZDBCJOHFCAS-UHFFFAOYSA-N 0.000 description 1
- 210000002700 urine Anatomy 0.000 description 1
- 125000000391 vinyl group Chemical group [H]C([*])=C([H])[H] 0.000 description 1
- 229920002554 vinyl polymer Polymers 0.000 description 1
- 230000003612 virological effect Effects 0.000 description 1
- 239000011782 vitamin Substances 0.000 description 1
- 229940088594 vitamin Drugs 0.000 description 1
- 229930003231 vitamin Natural products 0.000 description 1
- 235000013343 vitamin Nutrition 0.000 description 1
- 239000002023 wood Substances 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54393—Improving reaction conditions or stability, e.g. by coating or irradiation of surface, by reduction of non-specific binding, by promotion of specific binding
Landscapes
- Health & Medical Sciences (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Analytical Chemistry (AREA)
- Cell Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Food Science & Technology (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
- Peptides Or Proteins (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Priority Applications (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP58144201A JPS6035263A (ja) | 1983-08-05 | 1983-08-05 | 不溶性担体に固定化された免疫活性物質の安定化法及び該物質を構成単位として含む生理活性物質測定用試薬 |
| DE8484305286T DE3477844D1 (en) | 1983-08-05 | 1984-08-03 | Method for stabilizing immunologically active substances immobilized on an insoluble carrier and their use in the preparation of reagents for measuring physiologically active substances |
| EP84305286A EP0140489B1 (en) | 1983-08-05 | 1984-08-03 | Method for stabilizing immunologically active substances immobilized on an insoluble carrier and their use in the preparation of reagents for measuring physiologically active substances |
| AT84305286T ATE42410T1 (de) | 1983-08-05 | 1984-08-03 | Verfahren zur stabilisierung von, auf einem unloeslichen traeger, immobilisierten substanzen mit immunologischer wirksamkeit und ihre verwendung in der herstellung von reagenzien zur messung von substanzen mit physiologischer wirksamkeit. |
| US07/659,476 US5273908A (en) | 1983-08-05 | 1991-02-25 | Stabilizing method for immuno active substances immobilized on insoluble carrier and its use in preparation of reagent for measuring physiologically active substances |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP58144201A JPS6035263A (ja) | 1983-08-05 | 1983-08-05 | 不溶性担体に固定化された免疫活性物質の安定化法及び該物質を構成単位として含む生理活性物質測定用試薬 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS6035263A true JPS6035263A (ja) | 1985-02-23 |
| JPH0541946B2 JPH0541946B2 (en, 2012) | 1993-06-25 |
Family
ID=15356567
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP58144201A Granted JPS6035263A (ja) | 1983-08-05 | 1983-08-05 | 不溶性担体に固定化された免疫活性物質の安定化法及び該物質を構成単位として含む生理活性物質測定用試薬 |
Country Status (4)
| Country | Link |
|---|---|
| EP (1) | EP0140489B1 (en, 2012) |
| JP (1) | JPS6035263A (en, 2012) |
| AT (1) | ATE42410T1 (en, 2012) |
| DE (1) | DE3477844D1 (en, 2012) |
Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS61241665A (ja) * | 1985-04-18 | 1986-10-27 | Toyobo Co Ltd | 安定化された固相試薬 |
| JPS6234059A (ja) * | 1985-08-07 | 1987-02-14 | Sankyo Co Ltd | 固相化試薬の安定化剤 |
| JPH02161357A (ja) * | 1988-12-15 | 1990-06-21 | Tosoh Corp | 免疫測定用材料の安定化方法 |
| JPH02173568A (ja) * | 1988-11-09 | 1990-07-05 | Biotrack Inc | ラテックス試薬を安定化し、そして溶解するための方法及び組成物 |
| JP2010014685A (ja) * | 2008-07-04 | 2010-01-21 | Bio Matrix Research Inc | タンパク質安定化溶液 |
| JP2010230660A (ja) * | 2009-03-06 | 2010-10-14 | Kyowa Medex Co Ltd | 可溶性インターロイキン−２受容体定量用標準品 |
| JP2017181492A (ja) * | 2016-03-24 | 2017-10-05 | 三洋化成工業株式会社 | 粒子組成物、免疫測定用試薬及び免疫測定方法 |
| WO2018194134A1 (ja) * | 2017-04-20 | 2018-10-25 | 株式会社シノテスト | 抗ペリオスチン抗体固定化担体、ペリオスチン測定試薬、及び抗ペリオスチン抗体固定化担体における抗体の安定化方法 |
| JP2021071476A (ja) * | 2019-10-29 | 2021-05-06 | 三洋化成工業株式会社 | 免疫測定用試薬、免疫測定用キット及び免疫測定方法 |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2187191B (en) * | 1984-01-30 | 1989-11-01 | Quadrant Bioresources Ltd | Protection of proteins and the like |
| GB8500698D0 (en) * | 1985-01-11 | 1985-02-13 | Unilever Plc | Preparation of reagents |
| DE229810T1 (de) * | 1985-07-09 | 1987-11-05 | Quadrant Bioresources Ltd., Soulbury, Leighton Buzzard, Bedfordshire | Beschuetzung von proteinen und aehnlichem. |
| JPS62170850A (ja) * | 1986-01-23 | 1987-07-27 | Wako Pure Chem Ind Ltd | 免疫化学的測定法 |
| US5514602A (en) * | 1986-06-09 | 1996-05-07 | Ortho Diagnostic Systems, Inc. | Method of producing a metal sol reagent containing colloidal metal particles |
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| FR2616915B1 (fr) * | 1987-06-16 | 1989-09-29 | Ire Medgenix Sa | Solution d'une substance de nature polypeptidique, et utilisation pour des dosages immunologiques |
| GB8716826D0 (en) * | 1987-07-16 | 1987-08-19 | Tills D | Protection of proteinaceous reagents |
| GB8801338D0 (en) * | 1988-01-21 | 1988-02-17 | Quadrant Bioresources Ltd | Preservation of viruses |
| US5262296A (en) * | 1988-03-30 | 1993-11-16 | Toray Industries, Inc. | Freeze-dried composition containing enzyme-labeled anti-human interferon-β antibody and enzyme immunoassay kit containing the composition |
| DE3811659C1 (en, 2012) * | 1988-04-07 | 1989-11-16 | Henning Berlin Gmbh Chemie- Und Pharmawerk, 1000 Berlin, De | |
| US5077198A (en) * | 1988-04-14 | 1991-12-31 | Eastman Kodak Company | Diagnostic kit and method for rapid detection of antibodies |
| US5759774A (en) * | 1988-05-18 | 1998-06-02 | Cobe Laboratories, Inc. | Method of detecting circulating antibody types using dried or lyophilized cells |
| US5030560A (en) * | 1988-11-04 | 1991-07-09 | Immucor, Inc. | Method for drying mammalian cells for use in solid phase immunoassays and articles incorporating same |
| US5192663A (en) * | 1988-11-04 | 1993-03-09 | Immucor, Inc. | Article having an organic dye and a monolayer of dried mammalian cells and a method for utilizing the article |
| US5102788A (en) * | 1988-11-21 | 1992-04-07 | Hygeia Sciences, Inc. | Immunoassay including lyophilized reactant mixture |
| FR2645967B1 (fr) * | 1989-04-12 | 1994-04-01 | Diagnostica Stago | Procede d'adsorption d'un materiel immunologique, utilisation dans le domaine des reactions antigene/anticorps |
| USRE38385E1 (en) | 1989-02-16 | 2004-01-13 | Nektar Therapeutics | Storage of materials |
| GB8903593D0 (en) | 1989-02-16 | 1989-04-05 | Pafra Ltd | Storage of materials |
| US6352862B1 (en) | 1989-02-17 | 2002-03-05 | Unilever Patent Holdings B.V. | Analytical test device for imuno assays and methods of using same |
| DE3919393A1 (de) * | 1989-06-14 | 1990-12-20 | Hoechst Ag | Verfahren zur stabilisierung von auf festphasen immobilisierten biologisch aktiven substanzen |
| US6143508A (en) * | 1989-06-29 | 2000-11-07 | Rhone-Poulenc Rorer Pharmaceuticals Inc. | Device and process for cell capture and recovery |
| CA1340565C (en) | 1989-06-29 | 1999-05-25 | Thomas B. Okarma | Device and process for cell capture and recovery |
| AU633981B2 (en) * | 1989-10-12 | 1993-02-11 | Takeda Chemical Industries Ltd. | Antigen-sensitized bead and use thereof |
| US5252496A (en) * | 1989-12-18 | 1993-10-12 | Princeton Biomeditech Corporation | Carbon black immunochemical label |
| CA2053299A1 (en) * | 1990-02-28 | 1991-08-29 | Marvin A. Motsenbocker | Immunoassay |
| JPH0565233A (ja) * | 1991-03-08 | 1993-03-19 | Mitsui Toatsu Chem Inc | モノクローナル抗体含有凍結乾燥製剤 |
| AU659645B2 (en) | 1991-06-26 | 1995-05-25 | Inhale Therapeutic Systems | Storage of materials |
| ES2147185T3 (es) * | 1991-10-11 | 2000-09-01 | Abbott Lab | Composicion de reactivo en dosis unitaria para ensayos por union especifica. |
| JP3167415B2 (ja) * | 1992-04-30 | 2001-05-21 | オリンパス光学工業株式会社 | 固相免疫検査における抗原細胞の保存方法 |
| GB9211176D0 (en) * | 1992-05-27 | 1992-07-08 | Central Blood Lab Authority | Assay |
| US6582728B1 (en) | 1992-07-08 | 2003-06-24 | Inhale Therapeutic Systems, Inc. | Spray drying of macromolecules to produce inhaleable dry powders |
| US6509006B1 (en) | 1992-07-08 | 2003-01-21 | Inhale Therapeutic Systems, Inc. | Devices compositions and methods for the pulmonary delivery of aerosolized medicaments |
| CZ286632B6 (cs) | 1992-09-29 | 2000-05-17 | Inhale Therapeutic Systems | Farmaceutický prostředek |
| AU689217B2 (en) | 1994-03-07 | 1998-03-26 | Novartis Ag | Methods and compositions for pulmonary delivery of insulin |
| BE1008221A3 (fr) * | 1994-03-28 | 1996-02-20 | Anda Biolog Sa | Support solide fixant au moins un composant a activite biologique comprenant un site reactionnel, stabilise et procede pour son obtention. |
| US6290991B1 (en) | 1994-12-02 | 2001-09-18 | Quandrant Holdings Cambridge Limited | Solid dose delivery vehicle and methods of making same |
| US6309671B1 (en) | 1995-04-14 | 2001-10-30 | Inhale Therapeutic Systems | Stable glassy state powder formulations |
| US6979576B1 (en) | 1997-07-25 | 2005-12-27 | Shu-Ching Cheng | Methods of use of one step immunochromatographic device for Streptococcus A antigen |
| AU7590198A (en) * | 1997-06-10 | 1998-12-30 | Medlyte Diagnostics, Inc. | Methods for early detection of heart disease |
| IL121116A (en) * | 1997-06-19 | 2000-12-06 | Savyon Diagnostics Ltd | Stabilization of polypeptides for use in immunoassay procedures |
| US20060165606A1 (en) | 1997-09-29 | 2006-07-27 | Nektar Therapeutics | Pulmonary delivery particles comprising water insoluble or crystalline active agents |
| US6309623B1 (en) | 1997-09-29 | 2001-10-30 | Inhale Therapeutic Systems, Inc. | Stabilized preparations for use in metered dose inhalers |
| US6565885B1 (en) | 1997-09-29 | 2003-05-20 | Inhale Therapeutic Systems, Inc. | Methods of spray drying pharmaceutical compositions |
| FR2777355B1 (fr) * | 1998-04-10 | 2000-05-12 | Bio Merieux | Procede de fixation d'une molecule biologique sur la surface d'un support constitue de silice ou d'oxyde metallique |
| US8404217B2 (en) | 2000-05-10 | 2013-03-26 | Novartis Ag | Formulation for pulmonary administration of antifungal agents, and associated methods of manufacture and use |
| US7442388B2 (en) | 2000-05-10 | 2008-10-28 | Weers Jeffry G | Phospholipid-based powders for drug delivery |
| US7871598B1 (en) | 2000-05-10 | 2011-01-18 | Novartis Ag | Stable metal ion-lipid powdered pharmaceutical compositions for drug delivery and methods of use |
| ES2180416B1 (es) | 2001-03-12 | 2004-06-01 | BIOTOOLS BIOTECHNOLOGICAL & MEDICAL LABORATORIES, S.A. | Procedimiento para la preparacion de mezclas de reaccion estabilizadas, total o parcialmente desecadas, que comprenden, al menos, una enzima, mezclas de reaccion y kits que las contienen. |
| SI1458360T1 (sl) | 2001-12-19 | 2011-08-31 | Novartis Ag | Pulmonalno dajanje aminoglikozidov |
| US6927062B2 (en) | 2002-11-25 | 2005-08-09 | Agdia, Inc. | Controls and standards for assays and method for manufacture thereof |
| US20080050737A1 (en) * | 2006-05-23 | 2008-02-28 | Boaz Arieli | Ambient Temperature Stable Kits for Molecular Diagnostics |
| JP5349838B2 (ja) | 2007-11-30 | 2013-11-20 | 和光純薬工業株式会社 | ｓｍａｌｌＲＮＡの取得用担体、取得方法及び取得用試薬 |
| EP2230515B1 (en) | 2009-03-16 | 2014-12-17 | Agilent Technologies, Inc. | Passivation of surfaces after ligand coupling |
| KR102582192B1 (ko) | 2014-12-05 | 2023-09-25 | 후지필름 가부시키가이샤 | Tim 단백질 결합 담체, 당해 담체를 사용한 세포외막소포 및 바이러스의 취득 방법, 제거 방법, 검출 방법 그리고 당해 담체를 포함하는 키트 |
| JP7461382B2 (ja) | 2020-01-15 | 2024-04-03 | 富士フイルム株式会社 | 抗炎症剤、及び抗炎症作用を有する細胞外小胞の製造方法 |
| JP7425092B2 (ja) | 2020-01-15 | 2024-01-30 | 富士フイルム株式会社 | 抗線維化剤、及び抗線維化作用を有する細胞外小胞の製造方法 |
| JP7538150B2 (ja) | 2020-01-15 | 2024-08-21 | 富士フイルム株式会社 | 血管新生剤、及び血管新生作用を有する細胞外小胞の製造方法 |
| KR20250110928A (ko) | 2022-12-28 | 2025-07-21 | 후지필름 가부시키가이샤 | 다공질 담체, 세포 외 소포를 취득하는 방법, 세포 외 소포를 제조하는 방법, 및, 키트 |
| WO2025012398A1 (en) | 2023-07-11 | 2025-01-16 | Olink Proteomics Ab | Dried reagents |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS4921052A (en, 2012) * | 1972-06-16 | 1974-02-25 | ||
| JPS5423118A (en) * | 1977-07-25 | 1979-02-21 | Kitasato Inst | Vaccine for bibrio disease of bred fish |
| JPS57103649A (en) * | 1980-12-18 | 1982-06-28 | Asahi Chemical Ind | Sterilized gamma-globulin fixing column |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2016687B (en) * | 1978-03-20 | 1982-09-08 | Abbott Lab | Sugar coated reagents for solid phase immunoassay |
| JPH0235944B2 (en, 2012) * | 1980-06-20 | 1990-08-14 | Unilever Nv | |
| AR231590A1 (es) * | 1981-04-29 | 1984-12-28 | Ciba Geigy Ag | Dispositivo de analisis inmunologico y procedimiento para obtenerlo |
| JPS57182168A (en) * | 1981-05-02 | 1982-11-09 | Mitsubishi Chem Ind Ltd | Immunochemical reagent |
| GB2124231B (en) * | 1982-05-24 | 1985-10-02 | Corning Glass Works | Solid phase reagent for immunoassay |
-
1983
- 1983-08-05 JP JP58144201A patent/JPS6035263A/ja active Granted
-
1984
- 1984-08-03 EP EP84305286A patent/EP0140489B1/en not_active Expired
- 1984-08-03 AT AT84305286T patent/ATE42410T1/de not_active IP Right Cessation
- 1984-08-03 DE DE8484305286T patent/DE3477844D1/de not_active Expired
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS4921052A (en, 2012) * | 1972-06-16 | 1974-02-25 | ||
| JPS5423118A (en) * | 1977-07-25 | 1979-02-21 | Kitasato Inst | Vaccine for bibrio disease of bred fish |
| JPS57103649A (en) * | 1980-12-18 | 1982-06-28 | Asahi Chemical Ind | Sterilized gamma-globulin fixing column |
Cited By (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS61241665A (ja) * | 1985-04-18 | 1986-10-27 | Toyobo Co Ltd | 安定化された固相試薬 |
| JPS6234059A (ja) * | 1985-08-07 | 1987-02-14 | Sankyo Co Ltd | 固相化試薬の安定化剤 |
| JPH02173568A (ja) * | 1988-11-09 | 1990-07-05 | Biotrack Inc | ラテックス試薬を安定化し、そして溶解するための方法及び組成物 |
| JPH02161357A (ja) * | 1988-12-15 | 1990-06-21 | Tosoh Corp | 免疫測定用材料の安定化方法 |
| JP2010014685A (ja) * | 2008-07-04 | 2010-01-21 | Bio Matrix Research Inc | タンパク質安定化溶液 |
| JP2010230660A (ja) * | 2009-03-06 | 2010-10-14 | Kyowa Medex Co Ltd | 可溶性インターロイキン−２受容体定量用標準品 |
| JP2017181492A (ja) * | 2016-03-24 | 2017-10-05 | 三洋化成工業株式会社 | 粒子組成物、免疫測定用試薬及び免疫測定方法 |
| WO2018194134A1 (ja) * | 2017-04-20 | 2018-10-25 | 株式会社シノテスト | 抗ペリオスチン抗体固定化担体、ペリオスチン測定試薬、及び抗ペリオスチン抗体固定化担体における抗体の安定化方法 |
| JPWO2018194134A1 (ja) * | 2017-04-20 | 2020-02-27 | 株式会社シノテスト | 抗ペリオスチン抗体固定化担体、ペリオスチン測定試薬、及び抗ペリオスチン抗体固定化担体における抗体の安定化方法 |
| JP2021071476A (ja) * | 2019-10-29 | 2021-05-06 | 三洋化成工業株式会社 | 免疫測定用試薬、免疫測定用キット及び免疫測定方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| ATE42410T1 (de) | 1989-05-15 |
| EP0140489A1 (en) | 1985-05-08 |
| JPH0541946B2 (en, 2012) | 1993-06-25 |
| EP0140489B1 (en) | 1989-04-19 |
| DE3477844D1 (en) | 1989-05-24 |
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