DE3477844D1 - Method for stabilizing immunologically active substances immobilized on an insoluble carrier and their use in the preparation of reagents for measuring physiologically active substances - Google Patents

Method for stabilizing immunologically active substances immobilized on an insoluble carrier and their use in the preparation of reagents for measuring physiologically active substances

Info

Publication number
DE3477844D1
DE3477844D1 DE8484305286T DE3477844T DE3477844D1 DE 3477844 D1 DE3477844 D1 DE 3477844D1 DE 8484305286 T DE8484305286 T DE 8484305286T DE 3477844 T DE3477844 T DE 3477844T DE 3477844 D1 DE3477844 D1 DE 3477844D1
Authority
DE
Germany
Prior art keywords
active substances
reagents
stabilizing
preparation
insoluble carrier
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8484305286T
Other languages
English (en)
Inventor
Yoshitsugu Sakata
Yoshitaka Hamaguchi
Motoo Goto
Shinzo Kobatake
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fujifilm Wako Pure Chemical Corp
Original Assignee
Wako Pure Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=15356567&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE3477844(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Wako Pure Chemical Industries Ltd filed Critical Wako Pure Chemical Industries Ltd
Application granted granted Critical
Publication of DE3477844D1 publication Critical patent/DE3477844D1/de
Expired legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54393Improving reaction conditions or stability, e.g. by coating or irradiation of surface, by reduction of non-specific binding, by promotion of specific binding

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Food Science & Technology (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
DE8484305286T 1983-08-05 1984-08-03 Method for stabilizing immunologically active substances immobilized on an insoluble carrier and their use in the preparation of reagents for measuring physiologically active substances Expired DE3477844D1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP58144201A JPS6035263A (ja) 1983-08-05 1983-08-05 不溶性担体に固定化された免疫活性物質の安定化法及び該物質を構成単位として含む生理活性物質測定用試薬

Publications (1)

Publication Number Publication Date
DE3477844D1 true DE3477844D1 (en) 1989-05-24

Family

ID=15356567

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8484305286T Expired DE3477844D1 (en) 1983-08-05 1984-08-03 Method for stabilizing immunologically active substances immobilized on an insoluble carrier and their use in the preparation of reagents for measuring physiologically active substances

Country Status (4)

Country Link
EP (1) EP0140489B1 (de)
JP (1) JPS6035263A (de)
AT (1) ATE42410T1 (de)
DE (1) DE3477844D1 (de)

Families Citing this family (65)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2187191B (en) * 1984-01-30 1989-11-01 Quadrant Bioresources Ltd Protection of proteins and the like
GB8500698D0 (en) * 1985-01-11 1985-02-13 Unilever Plc Preparation of reagents
JPS61241665A (ja) * 1985-04-18 1986-10-27 Toyobo Co Ltd 安定化された固相試薬
EP0229810B1 (de) * 1985-07-09 1991-10-16 Quadrant Bioresources Limited Beschützung von proteinen und ähnlichem
JPS6234059A (ja) * 1985-08-07 1987-02-14 Sankyo Co Ltd 固相化試薬の安定化剤
JPS62170850A (ja) * 1986-01-23 1987-07-27 Wako Pure Chem Ind Ltd 免疫化学的測定法
US5514602A (en) * 1986-06-09 1996-05-07 Ortho Diagnostic Systems, Inc. Method of producing a metal sol reagent containing colloidal metal particles
EP0291194B8 (de) 1987-04-27 2003-10-22 Inverness Medical Switzerland GmbH Immunoassays und Vorrichtungen dafür
FR2616915B1 (fr) * 1987-06-16 1989-09-29 Ire Medgenix Sa Solution d'une substance de nature polypeptidique, et utilisation pour des dosages immunologiques
GB8716826D0 (en) * 1987-07-16 1987-08-19 Tills D Protection of proteinaceous reagents
GB8801338D0 (en) * 1988-01-21 1988-02-17 Quadrant Bioresources Ltd Preservation of viruses
US5262296A (en) * 1988-03-30 1993-11-16 Toray Industries, Inc. Freeze-dried composition containing enzyme-labeled anti-human interferon-β antibody and enzyme immunoassay kit containing the composition
DE3811659C1 (de) * 1988-04-07 1989-11-16 Henning Berlin Gmbh Chemie- Und Pharmawerk, 1000 Berlin, De
US5077198A (en) * 1988-04-14 1991-12-31 Eastman Kodak Company Diagnostic kit and method for rapid detection of antibodies
US5759774A (en) * 1988-05-18 1998-06-02 Cobe Laboratories, Inc. Method of detecting circulating antibody types using dried or lyophilized cells
US5192663A (en) * 1988-11-04 1993-03-09 Immucor, Inc. Article having an organic dye and a monolayer of dried mammalian cells and a method for utilizing the article
US5030560A (en) * 1988-11-04 1991-07-09 Immucor, Inc. Method for drying mammalian cells for use in solid phase immunoassays and articles incorporating same
AU609332B2 (en) * 1988-11-09 1991-04-26 Biotrack, Inc. Method and composition of stabilizing and solubilizing latex reagents
US5102788A (en) * 1988-11-21 1992-04-07 Hygeia Sciences, Inc. Immunoassay including lyophilized reactant mixture
JPH02161357A (ja) * 1988-12-15 1990-06-21 Tosoh Corp 免疫測定用材料の安定化方法
FR2645967B1 (fr) * 1989-04-12 1994-04-01 Diagnostica Stago Procede d'adsorption d'un materiel immunologique, utilisation dans le domaine des reactions antigene/anticorps
GB8903593D0 (en) 1989-02-16 1989-04-05 Pafra Ltd Storage of materials
USRE39497E1 (en) 1989-02-16 2007-02-27 Nektar Therapeutics Storage of materials
US6352862B1 (en) 1989-02-17 2002-03-05 Unilever Patent Holdings B.V. Analytical test device for imuno assays and methods of using same
DE3919393A1 (de) * 1989-06-14 1990-12-20 Hoechst Ag Verfahren zur stabilisierung von auf festphasen immobilisierten biologisch aktiven substanzen
US6143508A (en) * 1989-06-29 2000-11-07 Rhone-Poulenc Rorer Pharmaceuticals Inc. Device and process for cell capture and recovery
CA1340565C (en) * 1989-06-29 1999-05-25 Thomas B. Okarma Device and process for cell capture and recovery
AU633981B2 (en) * 1989-10-12 1993-02-11 Takeda Chemical Industries Ltd. Antigen-sensitized bead and use thereof
US5252496A (en) * 1989-12-18 1993-10-12 Princeton Biomeditech Corporation Carbon black immunochemical label
EP0473787A1 (de) * 1990-02-28 1992-03-11 Takeda Chemical Industries, Ltd. Verbesserter Immunoanalyse
JPH0565233A (ja) * 1991-03-08 1993-03-19 Mitsui Toatsu Chem Inc モノクローナル抗体含有凍結乾燥製剤
AU659645B2 (en) 1991-06-26 1995-05-25 Inhale Therapeutic Systems Storage of materials
DE69230828T2 (de) * 1991-10-11 2000-10-12 Abbott Laboratories, Abbott Park Gebrauchsfertige Reagenszusammensetzungseinheiten für einen spezifischen Bindungstest.
JP3167415B2 (ja) * 1992-04-30 2001-05-21 オリンパス光学工業株式会社 固相免疫検査における抗原細胞の保存方法
GB9211176D0 (en) * 1992-05-27 1992-07-08 Central Blood Lab Authority Assay
US6509006B1 (en) 1992-07-08 2003-01-21 Inhale Therapeutic Systems, Inc. Devices compositions and methods for the pulmonary delivery of aerosolized medicaments
US6582728B1 (en) 1992-07-08 2003-06-24 Inhale Therapeutic Systems, Inc. Spray drying of macromolecules to produce inhaleable dry powders
CZ295827B6 (cs) 1994-03-07 2005-11-16 Nektar Therapeutics Způsob aerosolizace dávky inzulinu, inzulinový přípravek a jeho použití
BE1008221A3 (fr) * 1994-03-28 1996-02-20 Anda Biolog Sa Support solide fixant au moins un composant a activite biologique comprenant un site reactionnel, stabilise et procede pour son obtention.
US6290991B1 (en) 1994-12-02 2001-09-18 Quandrant Holdings Cambridge Limited Solid dose delivery vehicle and methods of making same
US6309671B1 (en) 1995-04-14 2001-10-30 Inhale Therapeutic Systems Stable glassy state powder formulations
US6979576B1 (en) 1997-07-25 2005-12-27 Shu-Ching Cheng Methods of use of one step immunochromatographic device for Streptococcus A antigen
US6210976B1 (en) * 1997-06-10 2001-04-03 Medlyte Diagnostics, Inc. Methods for early detection of heart disease
IL121116A (en) * 1997-06-19 2000-12-06 Savyon Diagnostics Ltd Stabilization of polypeptides for use in immunoassay procedures
US20060165606A1 (en) 1997-09-29 2006-07-27 Nektar Therapeutics Pulmonary delivery particles comprising water insoluble or crystalline active agents
US6565885B1 (en) 1997-09-29 2003-05-20 Inhale Therapeutic Systems, Inc. Methods of spray drying pharmaceutical compositions
FR2777355B1 (fr) * 1998-04-10 2000-05-12 Bio Merieux Procede de fixation d'une molecule biologique sur la surface d'un support constitue de silice ou d'oxyde metallique
US7442388B2 (en) 2000-05-10 2008-10-28 Weers Jeffry G Phospholipid-based powders for drug delivery
US7871598B1 (en) 2000-05-10 2011-01-18 Novartis Ag Stable metal ion-lipid powdered pharmaceutical compositions for drug delivery and methods of use
US8404217B2 (en) 2000-05-10 2013-03-26 Novartis Ag Formulation for pulmonary administration of antifungal agents, and associated methods of manufacture and use
ES2180416B1 (es) 2001-03-12 2004-06-01 BIOTOOLS BIOTECHNOLOGICAL & MEDICAL LABORATORIES, S.A. Procedimiento para la preparacion de mezclas de reaccion estabilizadas, total o parcialmente desecadas, que comprenden, al menos, una enzima, mezclas de reaccion y kits que las contienen.
SI1458360T1 (sl) 2001-12-19 2011-08-31 Novartis Ag Pulmonalno dajanje aminoglikozidov
US6927062B2 (en) 2002-11-25 2005-08-09 Agdia, Inc. Controls and standards for assays and method for manufacture thereof
EP2210955A3 (de) * 2006-05-23 2010-09-15 Molecular Detection, Inc. Bei Umgebungstemperatur beständige Kits zur Molekulardiagnostik
JP5349838B2 (ja) 2007-11-30 2013-11-20 和光純薬工業株式会社 smallRNAの取得用担体、取得方法及び取得用試薬
JP2010014685A (ja) * 2008-07-04 2010-01-21 Bio Matrix Research Inc タンパク質安定化溶液
JP5832723B2 (ja) * 2009-03-06 2015-12-16 協和メデックス株式会社 可溶性インターロイキン−2受容体定量用標準品
EP2230515B1 (de) * 2009-03-16 2014-12-17 Agilent Technologies, Inc. Passivierung von Oberflächen nach Ligandenkupplung
CN113980089A (zh) 2014-12-05 2022-01-28 富士胶片和光纯药株式会社 一种检测试样中的细胞外膜囊泡的方法和检测用试剂盒的用途
JP6449221B2 (ja) * 2016-03-24 2019-01-09 三洋化成工業株式会社 粒子組成物、免疫測定用試薬及び免疫測定方法
JPWO2018194134A1 (ja) * 2017-04-20 2020-02-27 株式会社シノテスト 抗ペリオスチン抗体固定化担体、ペリオスチン測定試薬、及び抗ペリオスチン抗体固定化担体における抗体の安定化方法
JP7269906B2 (ja) * 2019-10-29 2023-05-09 三洋化成工業株式会社 免疫測定用試薬、免疫測定用キット及び免疫測定方法
EP4091617A4 (de) 2020-01-15 2023-08-09 FUJIFILM Corporation Antifibrotisches mittel und verfahren zum produzieren extrazellulärer vesikel, die eine antifibrotische wirkung aufweisen
JP7461382B2 (ja) 2020-01-15 2024-04-03 富士フイルム株式会社 抗炎症剤、及び抗炎症作用を有する細胞外小胞の製造方法
JPWO2021145396A1 (de) 2020-01-15 2021-07-22

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4921052A (de) * 1972-06-16 1974-02-25
JPS5423118A (en) * 1977-07-25 1979-02-21 Kitasato Inst Vaccine for bibrio disease of bred fish
GB2016687B (en) * 1978-03-20 1982-09-08 Abbott Lab Sugar coated reagents for solid phase immunoassay
WO1982000058A1 (en) * 1980-06-20 1982-01-07 Porter P Processes and apparatus for carrying out specific binding assays
JPS57103649A (en) * 1980-12-18 1982-06-28 Asahi Chemical Ind Sterilized gamma-globulin fixing column
AR231590A1 (es) * 1981-04-29 1984-12-28 Ciba Geigy Ag Dispositivo de analisis inmunologico y procedimiento para obtenerlo
JPS57182168A (en) * 1981-05-02 1982-11-09 Mitsubishi Chem Ind Ltd Immunochemical reagent
GB2124231B (en) * 1982-05-24 1985-10-02 Corning Glass Works Solid phase reagent for immunoassay

Also Published As

Publication number Publication date
EP0140489A1 (de) 1985-05-08
JPH0541946B2 (de) 1993-06-25
ATE42410T1 (de) 1989-05-15
EP0140489B1 (de) 1989-04-19
JPS6035263A (ja) 1985-02-23

Similar Documents

Publication Publication Date Title
DE3477844D1 (en) Method for stabilizing immunologically active substances immobilized on an insoluble carrier and their use in the preparation of reagents for measuring physiologically active substances
DE3160110D1 (en) Interference-resistant composition, device, method of preparing it and method for determining a peroxidatively active substance in a test sample
AU510807B2 (en) Test device and method for determining blood hemoglobin
DE3888577D1 (de) Gerät zur Messung von Elektrolyten.
NO892020D0 (no) Fremgangsmaate og apparat for bestemmelse av et immunologisk aktivt stoff.
EP0121192A3 (en) Analytical test composition, device, method for its preparation and method for the determination of peroxidatively active substance
EP0259857A3 (en) Method of assaying physiologically active substances
FI951710A0 (fi) Menetelmä merkkiainetta sisältävän tehoaineen konsetraation määrittämiseksi tehoaineliuoksessa
EP0279619A3 (en) Production of proteins in active forms
EP0351659A3 (en) Method and arrangement for measuring the concentration of optically active substances
NO171282C (no) Fremgangsmaate for bestemmelse av mikrobekonsentrasjoner med en smelteagarmetode, samt deri anvendte skaaler
IT8448540A0 (it) Proteine umane, antisieri per esse, procedimento per prepararli e corredi di prova che li contengono
EP0313095A3 (de) Verfahren zur Herstellung von Hydroxysilanen und/oder deren Oligomeren
EP0309360A3 (en) Electrochemical captor, with integrated structure, for measuring relative concentrations of reactive components
ATE100938T1 (de) Verfahren zur bestimmung der thyroxinbindekapazitaet und dazu geeignete standardloesung.
EP0337467A3 (en) Method for the determination of thyroxine and a standard solution therefore
EP0271964A3 (en) Method for preparing protein hydrolysates soluble in an acid environment, and the hydrolysates obtained
AU2647688A (en) Homogeneous aqueous solution electrolyte test
ATE78604T1 (de) Verwendung von polyvinylpyrrolidon (pvp) zur truebungsminderung von seren, seren enthaltend pvp und verfahren zu deren herstellung.
IL89225A0 (en) Method for detecting antibodies in blood,and membrane strip and membrane battery for use therein
JPS6438658A (en) Solid phase antibody for immunoassay
ZA935914B (en) Method and standard solution for the determination of thyroxine(T4) or triiodothyrorine(T3)
IL82558A0 (en) Method and apparatus for measuring blood glucose concentration
EP0116094A4 (de) Verfahren zur messung von säurekonzentration.
DE59000474D1 (de) Einrichtung zur strahlmodulation im strahlengang photometrischer analysatoren.

Legal Events

Date Code Title Description
8363 Opposition against the patent
8331 Complete revocation