JPH0541946B2 - - Google Patents

Info

Publication number
JPH0541946B2
JPH0541946B2 JP58144201A JP14420183A JPH0541946B2 JP H0541946 B2 JPH0541946 B2 JP H0541946B2 JP 58144201 A JP58144201 A JP 58144201A JP 14420183 A JP14420183 A JP 14420183A JP H0541946 B2 JPH0541946 B2 JP H0541946B2
Authority
JP
Japan
Prior art keywords
antibody
beads
carrier
phosphate buffer
immobilized
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP58144201A
Other languages
English (en)
Japanese (ja)
Other versions
JPS6035263A (ja
Inventor
Yoshitsugu Sakata
Yoshitaka Hamaguchi
Motoo Goto
Shinzo Obata
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fujifilm Wako Pure Chemical Corp
Original Assignee
Wako Pure Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=15356567&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=JPH0541946(B2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Wako Pure Chemical Industries Ltd filed Critical Wako Pure Chemical Industries Ltd
Priority to JP58144201A priority Critical patent/JPS6035263A/ja
Priority to DE8484305286T priority patent/DE3477844D1/de
Priority to EP84305286A priority patent/EP0140489B1/en
Priority to AT84305286T priority patent/ATE42410T1/de
Publication of JPS6035263A publication Critical patent/JPS6035263A/ja
Priority to US07/659,476 priority patent/US5273908A/en
Publication of JPH0541946B2 publication Critical patent/JPH0541946B2/ja
Granted legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54393—Improving reaction conditions or stability, e.g. by coating or irradiation of surface, by reduction of non-specific binding, by promotion of specific binding

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Food Science & Technology (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
JP58144201A 1983-08-05 1983-08-05 不溶性担体に固定化された免疫活性物質の安定化法及び該物質を構成単位として含む生理活性物質測定用試薬 Granted JPS6035263A (ja)

Priority Applications (5)

Application Number Priority Date Filing Date Title
JP58144201A JPS6035263A (ja) 1983-08-05 1983-08-05 不溶性担体に固定化された免疫活性物質の安定化法及び該物質を構成単位として含む生理活性物質測定用試薬
DE8484305286T DE3477844D1 (en) 1983-08-05 1984-08-03 Method for stabilizing immunologically active substances immobilized on an insoluble carrier and their use in the preparation of reagents for measuring physiologically active substances
EP84305286A EP0140489B1 (en) 1983-08-05 1984-08-03 Method for stabilizing immunologically active substances immobilized on an insoluble carrier and their use in the preparation of reagents for measuring physiologically active substances
AT84305286T ATE42410T1 (de) 1983-08-05 1984-08-03 Verfahren zur stabilisierung von, auf einem unloeslichen traeger, immobilisierten substanzen mit immunologischer wirksamkeit und ihre verwendung in der herstellung von reagenzien zur messung von substanzen mit physiologischer wirksamkeit.
US07/659,476 US5273908A (en) 1983-08-05 1991-02-25 Stabilizing method for immuno active substances immobilized on insoluble carrier and its use in preparation of reagent for measuring physiologically active substances

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP58144201A JPS6035263A (ja) 1983-08-05 1983-08-05 不溶性担体に固定化された免疫活性物質の安定化法及び該物質を構成単位として含む生理活性物質測定用試薬

Publications (2)

Publication Number Publication Date
JPS6035263A JPS6035263A (ja) 1985-02-23
JPH0541946B2 true JPH0541946B2 (en, 2012) 1993-06-25

Family

ID=15356567

Family Applications (1)

Application Number Title Priority Date Filing Date
JP58144201A Granted JPS6035263A (ja) 1983-08-05 1983-08-05 不溶性担体に固定化された免疫活性物質の安定化法及び該物質を構成単位として含む生理活性物質測定用試薬

Country Status (4)

Country Link
EP (1) EP0140489B1 (en, 2012)
JP (1) JPS6035263A (en, 2012)
AT (1) ATE42410T1 (en, 2012)
DE (1) DE3477844D1 (en, 2012)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009069711A1 (ja) 2007-11-30 2009-06-04 Wako Pure Chemical Industries, Ltd. small RNAの取得用担体、取得方法及び取得用試薬
EP3690041A1 (en) 2014-12-05 2020-08-05 FUJIFILM Wako Pure Chemical Corporation Tim protein-bound carrier, methods for obtaining, removing and detecting extracellular membrane vesicles and viruses using said carrier, and kit including said carrier
WO2021145396A1 (ja) 2020-01-15 2021-07-22 富士フイルム和光純薬株式会社 血管新生剤、及び血管新生作用を有する細胞外小胞の製造方法
WO2021145394A1 (ja) 2020-01-15 2021-07-22 富士フイルム和光純薬株式会社 抗炎症剤、及び抗炎症作用を有する細胞外小胞の製造方法
WO2021145395A1 (ja) 2020-01-15 2021-07-22 富士フイルム和光純薬株式会社 抗線維化剤、及び抗線維化作用を有する細胞外小胞の製造方法
WO2024143438A1 (ja) 2022-12-28 2024-07-04 富士フイルム株式会社 多孔質担体、細胞外小胞を取得する方法、細胞外小胞を製造する方法、及び、キット

Families Citing this family (63)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2187191B (en) * 1984-01-30 1989-11-01 Quadrant Bioresources Ltd Protection of proteins and the like
GB8500698D0 (en) * 1985-01-11 1985-02-13 Unilever Plc Preparation of reagents
JPS61241665A (ja) * 1985-04-18 1986-10-27 Toyobo Co Ltd 安定化された固相試薬
DE229810T1 (de) * 1985-07-09 1987-11-05 Quadrant Bioresources Ltd., Soulbury, Leighton Buzzard, Bedfordshire Beschuetzung von proteinen und aehnlichem.
JPS6234059A (ja) * 1985-08-07 1987-02-14 Sankyo Co Ltd 固相化試薬の安定化剤
JPS62170850A (ja) * 1986-01-23 1987-07-27 Wako Pure Chem Ind Ltd 免疫化学的測定法
US5514602A (en) * 1986-06-09 1996-05-07 Ortho Diagnostic Systems, Inc. Method of producing a metal sol reagent containing colloidal metal particles
EP1248112A3 (en) 1987-04-27 2004-08-25 Inverness Medical Switzerland GmbH Immunochromatographic specific binding assay device
FR2616915B1 (fr) * 1987-06-16 1989-09-29 Ire Medgenix Sa Solution d'une substance de nature polypeptidique, et utilisation pour des dosages immunologiques
GB8716826D0 (en) * 1987-07-16 1987-08-19 Tills D Protection of proteinaceous reagents
GB8801338D0 (en) * 1988-01-21 1988-02-17 Quadrant Bioresources Ltd Preservation of viruses
US5262296A (en) * 1988-03-30 1993-11-16 Toray Industries, Inc. Freeze-dried composition containing enzyme-labeled anti-human interferon-β antibody and enzyme immunoassay kit containing the composition
DE3811659C1 (en, 2012) * 1988-04-07 1989-11-16 Henning Berlin Gmbh Chemie- Und Pharmawerk, 1000 Berlin, De
US5077198A (en) * 1988-04-14 1991-12-31 Eastman Kodak Company Diagnostic kit and method for rapid detection of antibodies
US5759774A (en) * 1988-05-18 1998-06-02 Cobe Laboratories, Inc. Method of detecting circulating antibody types using dried or lyophilized cells
US5030560A (en) * 1988-11-04 1991-07-09 Immucor, Inc. Method for drying mammalian cells for use in solid phase immunoassays and articles incorporating same
US5192663A (en) * 1988-11-04 1993-03-09 Immucor, Inc. Article having an organic dye and a monolayer of dried mammalian cells and a method for utilizing the article
AU609332B2 (en) * 1988-11-09 1991-04-26 Biotrack, Inc. Method and composition of stabilizing and solubilizing latex reagents
US5102788A (en) * 1988-11-21 1992-04-07 Hygeia Sciences, Inc. Immunoassay including lyophilized reactant mixture
JPH02161357A (ja) * 1988-12-15 1990-06-21 Tosoh Corp 免疫測定用材料の安定化方法
FR2645967B1 (fr) * 1989-04-12 1994-04-01 Diagnostica Stago Procede d'adsorption d'un materiel immunologique, utilisation dans le domaine des reactions antigene/anticorps
USRE38385E1 (en) 1989-02-16 2004-01-13 Nektar Therapeutics Storage of materials
GB8903593D0 (en) 1989-02-16 1989-04-05 Pafra Ltd Storage of materials
US6352862B1 (en) 1989-02-17 2002-03-05 Unilever Patent Holdings B.V. Analytical test device for imuno assays and methods of using same
DE3919393A1 (de) * 1989-06-14 1990-12-20 Hoechst Ag Verfahren zur stabilisierung von auf festphasen immobilisierten biologisch aktiven substanzen
US6143508A (en) * 1989-06-29 2000-11-07 Rhone-Poulenc Rorer Pharmaceuticals Inc. Device and process for cell capture and recovery
CA1340565C (en) 1989-06-29 1999-05-25 Thomas B. Okarma Device and process for cell capture and recovery
AU633981B2 (en) * 1989-10-12 1993-02-11 Takeda Chemical Industries Ltd. Antigen-sensitized bead and use thereof
US5252496A (en) * 1989-12-18 1993-10-12 Princeton Biomeditech Corporation Carbon black immunochemical label
CA2053299A1 (en) * 1990-02-28 1991-08-29 Marvin A. Motsenbocker Immunoassay
JPH0565233A (ja) * 1991-03-08 1993-03-19 Mitsui Toatsu Chem Inc モノクローナル抗体含有凍結乾燥製剤
AU659645B2 (en) 1991-06-26 1995-05-25 Inhale Therapeutic Systems Storage of materials
ES2147185T3 (es) * 1991-10-11 2000-09-01 Abbott Lab Composicion de reactivo en dosis unitaria para ensayos por union especifica.
JP3167415B2 (ja) * 1992-04-30 2001-05-21 オリンパス光学工業株式会社 固相免疫検査における抗原細胞の保存方法
GB9211176D0 (en) * 1992-05-27 1992-07-08 Central Blood Lab Authority Assay
US6582728B1 (en) 1992-07-08 2003-06-24 Inhale Therapeutic Systems, Inc. Spray drying of macromolecules to produce inhaleable dry powders
US6509006B1 (en) 1992-07-08 2003-01-21 Inhale Therapeutic Systems, Inc. Devices compositions and methods for the pulmonary delivery of aerosolized medicaments
CZ286632B6 (cs) 1992-09-29 2000-05-17 Inhale Therapeutic Systems Farmaceutický prostředek
AU689217B2 (en) 1994-03-07 1998-03-26 Novartis Ag Methods and compositions for pulmonary delivery of insulin
BE1008221A3 (fr) * 1994-03-28 1996-02-20 Anda Biolog Sa Support solide fixant au moins un composant a activite biologique comprenant un site reactionnel, stabilise et procede pour son obtention.
US6290991B1 (en) 1994-12-02 2001-09-18 Quandrant Holdings Cambridge Limited Solid dose delivery vehicle and methods of making same
US6309671B1 (en) 1995-04-14 2001-10-30 Inhale Therapeutic Systems Stable glassy state powder formulations
US6979576B1 (en) 1997-07-25 2005-12-27 Shu-Ching Cheng Methods of use of one step immunochromatographic device for Streptococcus A antigen
AU7590198A (en) * 1997-06-10 1998-12-30 Medlyte Diagnostics, Inc. Methods for early detection of heart disease
IL121116A (en) * 1997-06-19 2000-12-06 Savyon Diagnostics Ltd Stabilization of polypeptides for use in immunoassay procedures
US20060165606A1 (en) 1997-09-29 2006-07-27 Nektar Therapeutics Pulmonary delivery particles comprising water insoluble or crystalline active agents
US6309623B1 (en) 1997-09-29 2001-10-30 Inhale Therapeutic Systems, Inc. Stabilized preparations for use in metered dose inhalers
US6565885B1 (en) 1997-09-29 2003-05-20 Inhale Therapeutic Systems, Inc. Methods of spray drying pharmaceutical compositions
FR2777355B1 (fr) * 1998-04-10 2000-05-12 Bio Merieux Procede de fixation d'une molecule biologique sur la surface d'un support constitue de silice ou d'oxyde metallique
US8404217B2 (en) 2000-05-10 2013-03-26 Novartis Ag Formulation for pulmonary administration of antifungal agents, and associated methods of manufacture and use
US7442388B2 (en) 2000-05-10 2008-10-28 Weers Jeffry G Phospholipid-based powders for drug delivery
US7871598B1 (en) 2000-05-10 2011-01-18 Novartis Ag Stable metal ion-lipid powdered pharmaceutical compositions for drug delivery and methods of use
ES2180416B1 (es) 2001-03-12 2004-06-01 BIOTOOLS BIOTECHNOLOGICAL & MEDICAL LABORATORIES, S.A. Procedimiento para la preparacion de mezclas de reaccion estabilizadas, total o parcialmente desecadas, que comprenden, al menos, una enzima, mezclas de reaccion y kits que las contienen.
SI1458360T1 (sl) 2001-12-19 2011-08-31 Novartis Ag Pulmonalno dajanje aminoglikozidov
US6927062B2 (en) 2002-11-25 2005-08-09 Agdia, Inc. Controls and standards for assays and method for manufacture thereof
US20080050737A1 (en) * 2006-05-23 2008-02-28 Boaz Arieli Ambient Temperature Stable Kits for Molecular Diagnostics
JP2010014685A (ja) * 2008-07-04 2010-01-21 Bio Matrix Research Inc タンパク質安定化溶液
JP5832723B2 (ja) * 2009-03-06 2015-12-16 協和メデックス株式会社 可溶性インターロイキン−２受容体定量用標準品
EP2230515B1 (en) 2009-03-16 2014-12-17 Agilent Technologies, Inc. Passivation of surfaces after ligand coupling
JP6449221B2 (ja) * 2016-03-24 2019-01-09 三洋化成工業株式会社 粒子組成物、免疫測定用試薬及び免疫測定方法
WO2018194134A1 (ja) * 2017-04-20 2018-10-25 株式会社シノテスト 抗ペリオスチン抗体固定化担体、ペリオスチン測定試薬、及び抗ペリオスチン抗体固定化担体における抗体の安定化方法
JP7269906B2 (ja) * 2019-10-29 2023-05-09 三洋化成工業株式会社 免疫測定用試薬、免疫測定用キット及び免疫測定方法
WO2025012398A1 (en) 2023-07-11 2025-01-16 Olink Proteomics Ab Dried reagents

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4921052A (en, 2012) * 1972-06-16 1974-02-25
JPS5423118A (en) * 1977-07-25 1979-02-21 Kitasato Inst Vaccine for bibrio disease of bred fish
GB2016687B (en) * 1978-03-20 1982-09-08 Abbott Lab Sugar coated reagents for solid phase immunoassay
JPH0235944B2 (en, 2012) * 1980-06-20 1990-08-14 Unilever Nv
JPS57103649A (en) * 1980-12-18 1982-06-28 Asahi Chemical Ind Sterilized gamma-globulin fixing column
AR231590A1 (es) * 1981-04-29 1984-12-28 Ciba Geigy Ag Dispositivo de analisis inmunologico y procedimiento para obtenerlo
JPS57182168A (en) * 1981-05-02 1982-11-09 Mitsubishi Chem Ind Ltd Immunochemical reagent
GB2124231B (en) * 1982-05-24 1985-10-02 Corning Glass Works Solid phase reagent for immunoassay

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009069711A1 (ja) 2007-11-30 2009-06-04 Wako Pure Chemical Industries, Ltd. small RNAの取得用担体、取得方法及び取得用試薬
EP3690041A1 (en) 2014-12-05 2020-08-05 FUJIFILM Wako Pure Chemical Corporation Tim protein-bound carrier, methods for obtaining, removing and detecting extracellular membrane vesicles and viruses using said carrier, and kit including said carrier
WO2021145396A1 (ja) 2020-01-15 2021-07-22 富士フイルム和光純薬株式会社 血管新生剤、及び血管新生作用を有する細胞外小胞の製造方法
WO2021145394A1 (ja) 2020-01-15 2021-07-22 富士フイルム和光純薬株式会社 抗炎症剤、及び抗炎症作用を有する細胞外小胞の製造方法
WO2021145395A1 (ja) 2020-01-15 2021-07-22 富士フイルム和光純薬株式会社 抗線維化剤、及び抗線維化作用を有する細胞外小胞の製造方法
WO2024143438A1 (ja) 2022-12-28 2024-07-04 富士フイルム株式会社 多孔質担体、細胞外小胞を取得する方法、細胞外小胞を製造する方法、及び、キット

Also Published As

Publication number Publication date
ATE42410T1 (de) 1989-05-15
JPS6035263A (ja) 1985-02-23
EP0140489A1 (en) 1985-05-08
EP0140489B1 (en) 1989-04-19
DE3477844D1 (en) 1989-05-24

Similar Documents

Publication Publication Date Title
JPH0541946B2 (en, 2012)
US4343896A (en) Method and test pack for the demonstration and determination of an antigen or antibody
US3966897A (en) Medium for use in bioassay and method of using same
US4434236A (en) Immunoassay wherein labeled antibody is displaced from immobilized analyte-analogue
US4243749A (en) Immunoassay employing an enzyme label
US4526871A (en) Conjugate obtained by coupling a lectin and a specific ligand, containing such a conjugate and its applications in biology
US4650751A (en) Protected binding assay avoiding non-specific protein interference
JPS6343711B2 (en, 2012)
GB2085160A (en) Measurement of free thyroxine or free 3,5,3'triiodothyronine in a liquid sample
JPS632348B2 (en, 2012)
JP2642342B2 (ja) 固相拡散試験法
KR890002942B1 (ko) 면역분석용 시약지의 제조 방법
US4971904A (en) Heterogeneous immunoassay
US4729961A (en) Process for the detection and assay by erythroadsorption
AU676469B2 (en) Method for the elimination of non-specific reactions in immunoassays
JPS6112547B2 (en, 2012)
JPS6232422B2 (en, 2012)
US5273908A (en) Stabilizing method for immuno active substances immobilized on insoluble carrier and its use in preparation of reagent for measuring physiologically active substances
Guesdon et al. Solid phase enzyme immunoassays
CN112326958A (zh) 一种微球封闭的方法及其微球标记的方法
US4510240A (en) Homogeneous enzyme immunoassay with heating step after incubation, THERESIA
GB2109931A (en) Enzyme immunoassay
JPH0566985B2 (en, 2012)
EP0253270B1 (en) Method for diagnostic immunoassay by solid phase separation
US5591598A (en) Method for quantitating hydrazide groups