JPS603045B2 - １α―ヒドロキシビタミンＤ類軟カプセルの製造方法 - Google Patents

１α―ヒドロキシビタミンＤ類軟カプセルの製造方法

Info

Publication number
JPS603045B2
JPS603045B2 JP51043615A JP4361576A JPS603045B2 JP S603045 B2 JPS603045 B2 JP S603045B2 JP 51043615 A JP51043615 A JP 51043615A JP 4361576 A JP4361576 A JP 4361576A JP S603045 B2 JPS603045 B2 JP S603045B2
Authority
JP
Japan
Prior art keywords
hydroxyvitamin
soft capsules
producing
sorbic acid
vitamin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
JP51043615A
Other languages
English (en)
Japanese (ja)
Other versions
JPS52128210A (en
Inventor
平二 幾島
弘人 中野
一夫 井草
貞雄 別所
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chugai Pharmaceutical Co Ltd
Original Assignee
Chugai Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chugai Pharmaceutical Co Ltd filed Critical Chugai Pharmaceutical Co Ltd
Priority to JP51043615A priority Critical patent/JPS603045B2/ja
Priority to US05/786,483 priority patent/US4164569A/en
Priority to GB15666/77A priority patent/GB1548812A/en
Priority to DE2716601A priority patent/DE2716601C2/de
Priority to FR7711600A priority patent/FR2348697A1/fr
Publication of JPS52128210A publication Critical patent/JPS52128210A/ja
Publication of JPS603045B2 publication Critical patent/JPS603045B2/ja
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Nutrition Science (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP51043615A 1976-04-19 1976-04-19 １α―ヒドロキシビタミンＤ類軟カプセルの製造方法 Expired JPS603045B2 (ja)

Priority Applications (5)

Application Number Priority Date Filing Date Title
JP51043615A JPS603045B2 (ja) 1976-04-19 1976-04-19 １α―ヒドロキシビタミンＤ類軟カプセルの製造方法
US05/786,483 US4164569A (en) 1976-04-19 1977-04-08 Stabilized soft gelatin capsule composition of 1 α-hydroxy-vitamin D
GB15666/77A GB1548812A (en) 1976-04-19 1977-04-14 Stabilized soft gelatin capsule preparation and process for preparing the same
DE2716601A DE2716601C2 (de) 1976-04-19 1977-04-14 Ein 1α-Hydroxy-Vitamin D und ein Öl enthaltendes Arzneimittel in einer Weichgelatinekapsel
FR7711600A FR2348697A1 (fr) 1976-04-19 1977-04-18 Composition stabilisee de 1alpha-hydroxy-vitamine d enfermee dans une gelule en gelatine molle et son procede de preparation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP51043615A JPS603045B2 (ja) 1976-04-19 1976-04-19 １α―ヒドロキシビタミンＤ類軟カプセルの製造方法

Publications (2)

Publication Number Publication Date
JPS52128210A JPS52128210A (en) 1977-10-27
JPS603045B2 true JPS603045B2 (ja) 1985-01-25

Family

ID=12668734

Family Applications (1)

Application Number Title Priority Date Filing Date
JP51043615A Expired JPS603045B2 (ja) 1976-04-19 1976-04-19 １α―ヒドロキシビタミンＤ類軟カプセルの製造方法

Country Status (5)

Country Link
US (1) US4164569A (enExample)
JP (1) JPS603045B2 (enExample)
DE (1) DE2716601C2 (enExample)
FR (1) FR2348697A1 (enExample)
GB (1) GB1548812A (enExample)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5452717A (en) * 1977-09-29 1979-04-25 Chugai Pharmaceut Co Ltd Stable oily pharmaceuticals containing 1alpha-hydroxyvitamin d
JPS5626820A (en) * 1979-08-10 1981-03-16 Chugai Pharmaceut Co Ltd Immunosuppressing agent
JPS5626819A (en) * 1979-08-10 1981-03-16 Chugai Pharmaceut Co Ltd Preventive for hypoimmunity
JPS5953410A (ja) * 1982-09-20 1984-03-28 Fujisawa Pharmaceut Co Ltd 新型ソフトカプセル剤
JPS6217A (ja) * 1985-02-14 1987-01-06 Chugai Pharmaceut Co Ltd 安定な活性型ビタミンｄ３類製剤
HU196559B (en) * 1987-04-17 1988-12-28 Biogal Gyogyszergyar Process for production of capsules of big stability from mild gelatine for medical purpuses containing as active substance of oils of natural origin
US4997824A (en) * 1987-07-22 1991-03-05 Teva Pharmaceutical Industries Ltd. Combination of cholecalciferol derivatives for the treatment of renal bone disease
US5043170A (en) * 1989-02-14 1991-08-27 Hoffmann-La Roche Inc. Animal feed composition containing a vitamin D metabolite
FI956073A7 (fi) * 1993-06-18 1996-02-16 Smithkline Beecham Corp Pehmeäkuoriset gelatiiniin kapseloidut osaset
GB9411115D0 (en) * 1994-06-03 1994-07-27 Secr Defence Stabilisation of photosensitive material
WO2004110380A2 (en) * 2003-06-11 2004-12-23 Novacea, Inc. Treatment of immune-mediated disorders with active vitamin d compounds alone or in combination with other therapeutic agents
CA2575396C (en) * 2004-07-30 2012-11-13 Wakunaga Pharmaceutical Co., Ltd. Composition for capsule coating, capsule coating, and capsule using the same
WO2009087652A2 (en) * 2007-10-19 2009-07-16 Usv Limited Pharmaceutical compositions of calcitriol and mineral supplements
JP5652723B2 (ja) * 2012-08-17 2015-01-14 フォーモサ・ラボラトリーズ・インコーポレーテッド マキサカルシトールの新しい結晶形態
US10130641B2 (en) * 2015-12-28 2018-11-20 Bruce L. Howe Compositions of vitamin D and methods for their use and manufacture

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2432698A (en) * 1945-02-15 1947-12-16 Taub Abraham Antioxidant stabilized material
US2862852A (en) * 1955-12-29 1958-12-02 Hoffmann La Roche Stabilized vitamin d composition
US3138532A (en) * 1962-04-02 1964-06-23 Hoffmann La Roche Water-dispersible gelatin compositions containing fat-soluble vitamin-active material, and preparation of droplets and beadlets
US3869539A (en) * 1966-12-01 1975-03-04 Ferrosan As Preparations containing fat-soluble vitamins in dry, particulate, free-flowing form dispersible in cold water and method of producing such preparations
US3864469A (en) * 1967-12-16 1975-02-04 Hoechst Ag Xanthines in pharmaceutical preparations and for stabilization of vitamins
US3833622A (en) * 1969-03-17 1974-09-03 Upjohn Co Crystalline 25-hydroxycholecalciferol hydrate and structurally related compounds
DE2019839A1 (de) 1969-04-28 1970-11-05 Ferrosan As Stabile,klare,wasserdispergierbare bzw.-verduennbare,Vitamin-A enthaltende Loesung und Verfahren zu ihrer Herstellung
AT312796B (de) * 1971-07-21 1974-01-25 Hoffmann La Roche Verfahren zur Herstellung eines Vitamin-E-Pulvers
US3741996A (en) * 1971-12-02 1973-06-26 Wisconsin Alumni Res Found 1{60 -hydroxycholecalciferol
PH9853A (en) * 1972-06-08 1976-04-13 M Francis Compositions for inhibiting mobilization of calcium phosphate in animal tissue and method of use thereof
JPS5115094B2 (enExample) * 1972-11-01 1976-05-14
US3887545A (en) * 1973-11-12 1975-06-03 Hoffmann La Roche Synthesis of 1{60 -hydroxylated cholesterol derivatives
US3907843A (en) * 1974-06-14 1975-09-23 Wisconsin Alumni Res Found 1{60 -Hydroxyergocalciferol and processes for preparing same

Also Published As

Publication number Publication date
GB1548812A (en) 1979-07-18
FR2348697B1 (enExample) 1981-07-10
DE2716601A1 (de) 1977-11-10
JPS52128210A (en) 1977-10-27
US4164569A (en) 1979-08-14
FR2348697A1 (fr) 1977-11-18
DE2716601C2 (de) 1986-09-11

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