DE2716601C2 - Ein 1α-Hydroxy-Vitamin D und ein Öl enthaltendes Arzneimittel in einer Weichgelatinekapsel - Google Patents

Ein 1α-Hydroxy-Vitamin D und ein Öl enthaltendes Arzneimittel in einer Weichgelatinekapsel

Info

Publication number
DE2716601C2
DE2716601C2 DE2716601A DE2716601A DE2716601C2 DE 2716601 C2 DE2716601 C2 DE 2716601C2 DE 2716601 A DE2716601 A DE 2716601A DE 2716601 A DE2716601 A DE 2716601A DE 2716601 C2 DE2716601 C2 DE 2716601C2
Authority
DE
Germany
Prior art keywords
vitamin
soft gelatin
oil
gelatin capsule
hydroxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE2716601A
Other languages
German (de)
English (en)
Other versions
DE2716601A1 (de
Inventor
Sadao Tokio/Tokyo Bessho
Kazuo Tokorozawa Saitama Igusa
Heizi Kawaguchi Saitama Ikushima
Hiroto Kodairo Tokio/Tokyo Nakano
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chugai Pharmaceutical Co Ltd
Original Assignee
Chugai Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chugai Pharmaceutical Co Ltd filed Critical Chugai Pharmaceutical Co Ltd
Publication of DE2716601A1 publication Critical patent/DE2716601A1/de
Application granted granted Critical
Publication of DE2716601C2 publication Critical patent/DE2716601C2/de
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Nutrition Science (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE2716601A 1976-04-19 1977-04-14 Ein 1α-Hydroxy-Vitamin D und ein Öl enthaltendes Arzneimittel in einer Weichgelatinekapsel Expired DE2716601C2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP51043615A JPS603045B2 (ja) 1976-04-19 1976-04-19 １α―ヒドロキシビタミンＤ類軟カプセルの製造方法

Publications (2)

Publication Number Publication Date
DE2716601A1 DE2716601A1 (de) 1977-11-10
DE2716601C2 true DE2716601C2 (de) 1986-09-11

Family

ID=12668734

Family Applications (1)

Application Number Title Priority Date Filing Date
DE2716601A Expired DE2716601C2 (de) 1976-04-19 1977-04-14 Ein 1α-Hydroxy-Vitamin D und ein Öl enthaltendes Arzneimittel in einer Weichgelatinekapsel

Country Status (5)

Country Link
US (1) US4164569A (enExample)
JP (1) JPS603045B2 (enExample)
DE (1) DE2716601C2 (enExample)
FR (1) FR2348697A1 (enExample)
GB (1) GB1548812A (enExample)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5452717A (en) * 1977-09-29 1979-04-25 Chugai Pharmaceut Co Ltd Stable oily pharmaceuticals containing 1alpha-hydroxyvitamin d
JPS5626820A (en) * 1979-08-10 1981-03-16 Chugai Pharmaceut Co Ltd Immunosuppressing agent
JPS5626819A (en) * 1979-08-10 1981-03-16 Chugai Pharmaceut Co Ltd Preventive for hypoimmunity
JPS5953410A (ja) * 1982-09-20 1984-03-28 Fujisawa Pharmaceut Co Ltd 新型ソフトカプセル剤
JPS6217A (ja) * 1985-02-14 1987-01-06 Chugai Pharmaceut Co Ltd 安定な活性型ビタミンｄ３類製剤
HU196559B (en) * 1987-04-17 1988-12-28 Biogal Gyogyszergyar Process for production of capsules of big stability from mild gelatine for medical purpuses containing as active substance of oils of natural origin
US4997824A (en) * 1987-07-22 1991-03-05 Teva Pharmaceutical Industries Ltd. Combination of cholecalciferol derivatives for the treatment of renal bone disease
US5043170A (en) * 1989-02-14 1991-08-27 Hoffmann-La Roche Inc. Animal feed composition containing a vitamin D metabolite
FI956073A7 (fi) * 1993-06-18 1996-02-16 Smithkline Beecham Corp Pehmeäkuoriset gelatiiniin kapseloidut osaset
GB9411115D0 (en) * 1994-06-03 1994-07-27 Secr Defence Stabilisation of photosensitive material
WO2004110380A2 (en) * 2003-06-11 2004-12-23 Novacea, Inc. Treatment of immune-mediated disorders with active vitamin d compounds alone or in combination with other therapeutic agents
CA2575396C (en) * 2004-07-30 2012-11-13 Wakunaga Pharmaceutical Co., Ltd. Composition for capsule coating, capsule coating, and capsule using the same
WO2009087652A2 (en) * 2007-10-19 2009-07-16 Usv Limited Pharmaceutical compositions of calcitriol and mineral supplements
JP5652723B2 (ja) * 2012-08-17 2015-01-14 フォーモサ・ラボラトリーズ・インコーポレーテッド マキサカルシトールの新しい結晶形態
US10130641B2 (en) * 2015-12-28 2018-11-20 Bruce L. Howe Compositions of vitamin D and methods for their use and manufacture

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2432698A (en) * 1945-02-15 1947-12-16 Taub Abraham Antioxidant stabilized material
US2862852A (en) * 1955-12-29 1958-12-02 Hoffmann La Roche Stabilized vitamin d composition
US3138532A (en) * 1962-04-02 1964-06-23 Hoffmann La Roche Water-dispersible gelatin compositions containing fat-soluble vitamin-active material, and preparation of droplets and beadlets
US3869539A (en) * 1966-12-01 1975-03-04 Ferrosan As Preparations containing fat-soluble vitamins in dry, particulate, free-flowing form dispersible in cold water and method of producing such preparations
US3864469A (en) * 1967-12-16 1975-02-04 Hoechst Ag Xanthines in pharmaceutical preparations and for stabilization of vitamins
US3833622A (en) * 1969-03-17 1974-09-03 Upjohn Co Crystalline 25-hydroxycholecalciferol hydrate and structurally related compounds
DE2019839A1 (de) 1969-04-28 1970-11-05 Ferrosan As Stabile,klare,wasserdispergierbare bzw.-verduennbare,Vitamin-A enthaltende Loesung und Verfahren zu ihrer Herstellung
AT312796B (de) * 1971-07-21 1974-01-25 Hoffmann La Roche Verfahren zur Herstellung eines Vitamin-E-Pulvers
US3741996A (en) * 1971-12-02 1973-06-26 Wisconsin Alumni Res Found 1{60 -hydroxycholecalciferol
PH9853A (en) * 1972-06-08 1976-04-13 M Francis Compositions for inhibiting mobilization of calcium phosphate in animal tissue and method of use thereof
JPS5115094B2 (enExample) * 1972-11-01 1976-05-14
US3887545A (en) * 1973-11-12 1975-06-03 Hoffmann La Roche Synthesis of 1{60 -hydroxylated cholesterol derivatives
US3907843A (en) * 1974-06-14 1975-09-23 Wisconsin Alumni Res Found 1{60 -Hydroxyergocalciferol and processes for preparing same

Also Published As

Publication number Publication date
GB1548812A (en) 1979-07-18
FR2348697B1 (enExample) 1981-07-10
DE2716601A1 (de) 1977-11-10
JPS603045B2 (ja) 1985-01-25
JPS52128210A (en) 1977-10-27
US4164569A (en) 1979-08-14
FR2348697A1 (fr) 1977-11-18

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Legal Events

Date Code Title Description
8110 Request for examination paragraph 44
D2 Grant after examination
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee