DE69419019T2 - Gelatinekaiseln die eine hochdosierte acetaminophenlösung enthalten - Google Patents

Gelatinekaiseln die eine hochdosierte acetaminophenlösung enthalten

Info

Publication number
DE69419019T2
DE69419019T2 DE69419019T DE69419019T DE69419019T2 DE 69419019 T2 DE69419019 T2 DE 69419019T2 DE 69419019 T DE69419019 T DE 69419019T DE 69419019 T DE69419019 T DE 69419019T DE 69419019 T2 DE69419019 T2 DE 69419019T2
Authority
DE
Germany
Prior art keywords
caisels
acetaminophene
gelatine
solution
high dose
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69419019T
Other languages
English (en)
Other versions
DE69419019D1 (de
Inventor
Rickey S Shelley
Youching Wei
Deborah Linking
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Catalent Pharma Solutions Inc
Original Assignee
Catalent Pharma Solutions Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26799397&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69419019(T2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Catalent Pharma Solutions Inc filed Critical Catalent Pharma Solutions Inc
Application granted granted Critical
Publication of DE69419019D1 publication Critical patent/DE69419019D1/de
Publication of DE69419019T2 publication Critical patent/DE69419019T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds
DE69419019T 1993-08-05 1994-08-04 Gelatinekaiseln die eine hochdosierte acetaminophenlösung enthalten Expired - Lifetime DE69419019T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US10246493A 1993-08-05 1993-08-05
US08/263,630 US5505961A (en) 1993-08-05 1994-06-22 Gelatin capsules containing a highly concentrated acetaminophen solution
PCT/US1994/008790 WO1995004527A1 (en) 1993-08-05 1994-08-04 Gelatin capsules containing a highly concentrated acetaminophen solution

Publications (2)

Publication Number Publication Date
DE69419019D1 DE69419019D1 (de) 1999-07-15
DE69419019T2 true DE69419019T2 (de) 1999-11-11

Family

ID=26799397

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69419019T Expired - Lifetime DE69419019T2 (de) 1993-08-05 1994-08-04 Gelatinekaiseln die eine hochdosierte acetaminophenlösung enthalten

Country Status (10)

Country Link
US (1) US5505961A (de)
EP (1) EP0713390B1 (de)
JP (1) JP3678745B2 (de)
KR (1) KR100341522B1 (de)
AU (1) AU701771B2 (de)
BR (1) BR9407178A (de)
CA (1) CA2168732C (de)
DE (1) DE69419019T2 (de)
ES (1) ES2134953T3 (de)
WO (1) WO1995004527A1 (de)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE398448T1 (de) 1993-09-28 2008-07-15 Scherer Gmbh R P Herstellung von weichgelatinekapseln
GB9325445D0 (en) 1993-12-13 1994-02-16 Cortecs Ltd Pharmaceutical formulations
US5484606A (en) * 1994-01-24 1996-01-16 The Procter & Gamble Company Process for reducing the precipitation of difficulty soluble pharmaceutical actives
US5510389A (en) * 1994-03-02 1996-04-23 The Procter & Gamble Company Concentrated acetaminophen solution compositions
US5660859A (en) * 1994-12-29 1997-08-26 Mcneil-Ppc, Inc. Gelling agent for polyethylene glycol
NZ280610A (en) * 1994-12-29 1997-08-22 Mcneil Ppc Inc Soft gelatin-like pharmaceutical carrier: gelled polyethylene glycol and dispersed active agent
US5641512A (en) * 1995-03-29 1997-06-24 The Procter & Gamble Company Soft gelatin capsule compositions
US5770215A (en) * 1997-01-06 1998-06-23 Moshyedi; Emil Payman Multivitamin/vascular occlusion inhibiting composition
KR100578669B1 (ko) * 1997-05-29 2006-12-07 동아제약주식회사 우르소데옥시콜린산을함유하는투명연질캅셀
US6365180B1 (en) * 1998-01-20 2002-04-02 Glenn A. Meyer Oral liquid compositions
EP1049459B1 (de) 1998-01-20 2009-04-22 Applied Analytical Industries, Inc. Orale flüssige zusammensetzungen
US6846495B2 (en) 1999-01-11 2005-01-25 The Procter & Gamble Company Compositions having improved delivery of actives
US6383515B2 (en) 1999-05-28 2002-05-07 Sawyer Maryjean Solvent system for enhancing solubility
IT1313579B1 (it) * 1999-07-30 2002-09-09 Acraf Composizione farmaceutica liquida a base di paracetamolo.
US20030034458A1 (en) * 2001-03-30 2003-02-20 Fuji Photo Film Co., Ltd. Radiation image storage panel
US7138133B2 (en) 2001-10-10 2006-11-21 The Procter & Gamble Company Orally administered liquid compositions
US7029698B2 (en) * 2001-11-21 2006-04-18 R.P. Scherer Technologies, Inc. Acetaminophen compositions
US7101572B2 (en) * 2001-12-07 2006-09-05 Unilab Pharmatech, Ltd. Taste masked aqueous liquid pharmaceutical composition
US20060088590A1 (en) * 2004-10-22 2006-04-27 Banner Pharmacaps, Inc. Non-blooming gelatin and non-gelatin formulations
US8231896B2 (en) * 2004-11-08 2012-07-31 R.P. Scherer Technologies, Llc Non-gelatin soft capsule system
US20070053868A1 (en) 2005-03-08 2007-03-08 Banner Pharmacaps, Inc. Solvent system for enhancing the solubility of pharmaceutical agents
US8333989B2 (en) * 2005-10-26 2012-12-18 Banner Pharmacaps, Inc. Hydrophilic vehicle-based dual controlled release matrix system
CN100364521C (zh) * 2005-12-22 2008-01-30 浙江万联药业有限公司 含对乙酰氨基酚的软胶囊组合物
WO2008070950A1 (en) * 2006-12-13 2008-06-19 Laboratoires Mauves Inc. Pharmaceutical solution formulations for encapsulation into gelatin capsules or other dosage forms
CN101909601B (zh) 2008-01-18 2013-06-26 陶氏环球技术公司 使用甲氧基聚乙二醇增强难溶性活性剂的水溶解度的方法
US8518439B2 (en) * 2008-12-03 2013-08-27 Novartis Ag Liquid therapeutic composition
US8518438B2 (en) * 2011-01-14 2013-08-27 Enspire Group, Llc Highly concentrated liquid acetaminophen solutions
US8969416B2 (en) * 2012-03-29 2015-03-03 Enspire Group LLC Polyvinylpyrrolidone-containing acetaminophen liquid formulations
PL2961377T3 (pl) 2013-02-28 2020-11-02 Pf Consumer Healthcare 1 Llc Zwiększona stabilność nowych ciekłych kompozycji
US20140275151A1 (en) * 2013-03-15 2014-09-18 Mahesh Sudhakar BHARATI Dye free liquid therapeutic solution
SG11201507369WA (en) * 2013-03-15 2015-10-29 Novartis Consumer Health Inc Dye free liquid therapeutic solution
WO2016084099A1 (en) * 2014-11-25 2016-06-02 Biological E Limited Soft gelatin capsule composition of anti-tussive agents
US10188133B2 (en) 2015-04-23 2019-01-29 Basf Se Gel capsule containing sterol and solubilising agent
MX2020012233A (es) 2018-05-16 2021-01-29 Bayer Healthcare Llc Formula de suspension de alta concentracion para medicamentos en capsula de gel blanda para resfriado y gripe.
KR102050069B1 (ko) * 2019-03-29 2019-11-28 (주)알피바이오 안정성이 향상된 연질캡슐 제제용 충진조성물 및 이를 포함하는 연질캡슐 제제

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3956490A (en) * 1972-05-22 1976-05-11 Interx Research Corporation Administration of alkaline earth metal salts of salicylamide
US4708834A (en) * 1986-05-01 1987-11-24 Pharmacaps, Inc. Preparation of gelatin-encapsulated controlled release composition
US5071643A (en) * 1986-10-17 1991-12-10 R. P. Scherer Corporation Solvent system enhancing the solubility of pharmaceuticals for encapsulation

Also Published As

Publication number Publication date
KR100341522B1 (ko) 2002-11-23
BR9407178A (pt) 1996-09-17
CA2168732A1 (en) 1995-02-16
JPH09503495A (ja) 1997-04-08
AU701771B2 (en) 1999-02-04
CA2168732C (en) 1999-10-12
KR960703576A (ko) 1996-08-31
EP0713390B1 (de) 1999-06-09
JP3678745B2 (ja) 2005-08-03
DE69419019D1 (de) 1999-07-15
AU7629994A (en) 1995-02-28
ES2134953T3 (es) 1999-10-16
WO1995004527A1 (en) 1995-02-16
US5505961A (en) 1996-04-09
EP0713390A1 (de) 1996-05-29

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8328 Change in the person/name/address of the agent

Representative=s name: PFENNING MEINIG & PARTNER GBR, 80339 MUENCHEN

8328 Change in the person/name/address of the agent

Representative=s name: MAIWALD PATENTANWALTSGESELLSCHAFT MBH, 80335 MUENC