JPS5953920B2 - 新規なアミノ糖化合物およびその製法 - Google Patents

新規なアミノ糖化合物およびその製法

Info

Publication number
JPS5953920B2
JPS5953920B2 JP52157328A JP15732877A JPS5953920B2 JP S5953920 B2 JPS5953920 B2 JP S5953920B2 JP 52157328 A JP52157328 A JP 52157328A JP 15732877 A JP15732877 A JP 15732877A JP S5953920 B2 JPS5953920 B2 JP S5953920B2
Authority
JP
Japan
Prior art keywords
amino sugar
sugar compound
compound
general formula
fraction
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
JP52157328A
Other languages
English (en)
Japanese (ja)
Other versions
JPS5492909A (en
Inventor
勝 小谷
哲 斉藤
秀三 里井
順三 溝口
直紀 武藤
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Toyo Jozo KK
Original Assignee
Toyo Jozo KK
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Toyo Jozo KK filed Critical Toyo Jozo KK
Priority to JP52157328A priority Critical patent/JPS5953920B2/ja
Priority to US05/968,697 priority patent/US4254256A/en
Priority to GB7849181A priority patent/GB2011397B/en
Priority to DE19782855409 priority patent/DE2855409A1/de
Priority to FR7836790A priority patent/FR2413401A1/fr
Publication of JPS5492909A publication Critical patent/JPS5492909A/ja
Publication of JPS5953920B2 publication Critical patent/JPS5953920B2/ja
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/465—Streptomyces

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Diabetes (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Emergency Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Endocrinology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
JP52157328A 1977-12-28 1977-12-28 新規なアミノ糖化合物およびその製法 Expired JPS5953920B2 (ja)

Priority Applications (5)

Application Number Priority Date Filing Date Title
JP52157328A JPS5953920B2 (ja) 1977-12-28 1977-12-28 新規なアミノ糖化合物およびその製法
US05/968,697 US4254256A (en) 1977-12-28 1978-12-12 Amino sugar compound
GB7849181A GB2011397B (en) 1977-12-28 1978-12-20 Amino sugar compound and method for producing same
DE19782855409 DE2855409A1 (de) 1977-12-28 1978-12-21 Neue aminozucker und verfahren zu ihrer gewinnung
FR7836790A FR2413401A1 (fr) 1977-12-28 1978-12-28 Nouveaux derives de sucres amines, leur preparation et leur utilisation therapeutique

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP52157328A JPS5953920B2 (ja) 1977-12-28 1977-12-28 新規なアミノ糖化合物およびその製法

Publications (2)

Publication Number Publication Date
JPS5492909A JPS5492909A (en) 1979-07-23
JPS5953920B2 true JPS5953920B2 (ja) 1984-12-27

Family

ID=15647283

Family Applications (1)

Application Number Title Priority Date Filing Date
JP52157328A Expired JPS5953920B2 (ja) 1977-12-28 1977-12-28 新規なアミノ糖化合物およびその製法

Country Status (5)

Country Link
US (1) US4254256A (en:Method)
JP (1) JPS5953920B2 (en:Method)
DE (1) DE2855409A1 (en:Method)
FR (1) FR2413401A1 (en:Method)
GB (1) GB2011397B (en:Method)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS62136868U (en:Method) * 1986-02-21 1987-08-28

Families Citing this family (44)

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JPS57146713A (en) * 1981-03-09 1982-09-10 Akira Endo Hypoglycemic
US4526784A (en) * 1981-05-05 1985-07-02 Bayer Aktiengesellschaft Amino-cyclitol derivatives and medicaments containing them
DE3123520A1 (de) * 1981-06-13 1982-12-30 Bayer Ag, 5090 Leverkusen Gesaettigte aminocyclitderivate, ihre herstellung undsie enthaltende arzneimittel
DE3134591A1 (de) * 1981-09-01 1983-03-10 Bayer Ag, 5090 Leverkusen Neue arzneimittelpraeparationen fuer glykosidhydrolasen-inhibitoren
US4595678A (en) * 1982-03-19 1986-06-17 Takeda Chemical Industries, Ltd. N-substituted pseudo-aminosugars and pharmaceutical compositions containing same
EP0173950A3 (de) * 1984-09-04 1987-10-28 Hoechst Aktiengesellschaft Neuer alpha-Glukosidase Inhibitor, Verfahren zur seiner Herstellung, seine Verwendung und pharmazeutische Präparate
EP0173948A3 (de) * 1984-09-04 1987-11-04 Hoechst Aktiengesellschaft Neue Pseudooligosaccharide mit alpha-Glukosidase-hemmender Wirkung, Verfahren zur deren Herstellung, deren Verwendung und pharmazeutische Präparate
DE3836675A1 (de) * 1988-10-28 1990-05-03 Hoechst Ag Glykosidase-inhibitor salbostatin, verfahren zu seiner herstellung und seine verwendung
TW381025B (en) * 1993-08-05 2000-02-01 Hoffmann La Roche Pharmaceutical composition containing a glucosidase inhibitor and a lipase inhibitor
ATE422359T1 (de) * 1997-04-15 2009-02-15 Csir Verbindungen und pharmazeutische zusammensetzungen mit appetitunterdrückender aktivität
DE19748195A1 (de) 1997-10-31 1999-05-06 Suedzucker Ag Disaccharidderivate zur Behandlung von Hyperglykämien
GB2396815B (en) * 1999-10-27 2004-09-08 Phytopharm Plc A composition comprising a pregnenone derivative and an NSAID
GB2363985B (en) 2000-06-30 2004-09-29 Phytopharm Plc Extracts,compounds & pharmaceutical compositions having anti-diabetic activity and their use
US7262318B2 (en) * 2004-03-10 2007-08-28 Pfizer, Inc. Substituted heteroaryl- and phenylsulfamoyl compounds
US20050288340A1 (en) * 2004-06-29 2005-12-29 Pfizer Inc Substituted heteroaryl- and phenylsulfamoyl compounds
AU2005308575A1 (en) * 2004-11-23 2006-06-01 Warner-Lambert Company Llc 7-(2h-pyrazol-3-yl)-3, 5-dihyroxy-heptanoic acid derivatives as HMG Co-A reductase inhibitors for the treatment of lipidemia
JP5000874B2 (ja) * 2005-03-29 2012-08-15 三井製糖株式会社 スクラーゼ活性又はグルコアミラーゼ活性を阻害する剤
US7741317B2 (en) 2005-10-21 2010-06-22 Bristol-Myers Squibb Company LXR modulators
US7888376B2 (en) 2005-11-23 2011-02-15 Bristol-Myers Squibb Company Heterocyclic CETP inhibitors
JP5498168B2 (ja) 2006-12-01 2014-05-21 ブリストル−マイヤーズ スクイブ カンパニー アテローム性動脈硬化および循環器疾患の治療のためのｃｅｔｐ阻害剤としてのｎ−（（３−ベンジル）−２，２−（ビス−フェニル）−プロパン−１−アミン誘導体
ATE518544T1 (de) 2007-03-12 2011-08-15 Zadec Aps Rotbusch-extrakt gegen diabetes
US8969514B2 (en) 2007-06-04 2015-03-03 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
MX2009013293A (es) 2007-06-04 2010-02-15 Synergy Pharmaceuticals Inc Agonistas de guanilato ciclasa útiles para el tratamiento de trastornos gastrointestinales, inflamación, cáncer y otros trastornos.
WO2009006620A1 (en) 2007-07-03 2009-01-08 Children's Hospital & Research Center At Oakland Oligosialic acid derivatives, methods of manufacture, and immunological uses
AU2008272785B2 (en) * 2007-07-03 2014-06-12 Children's Hospital & Research Center At Oakland Polysialic acid derivatives, methods of production, and uses in enhancing cancer antigen production and targeting
US8999954B2 (en) * 2007-07-03 2015-04-07 Childern's Hospital & Research Center at Oakland Inhibitors of polysialic acid de-N-acetylase and methods for using the same
EP2810951B1 (en) 2008-06-04 2017-03-15 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
EP2145538A1 (de) 2008-07-15 2010-01-20 Georg-August-Universität Göttingen Stiftung Öffentlichen Rechts Pflanzen- und Materialschutzmittel
CA2730603C (en) 2008-07-16 2019-09-24 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
CA2799708A1 (en) 2010-05-21 2011-11-24 Pfizer Inc. 2-phenyl benzoylamides
US20130156720A1 (en) 2010-08-27 2013-06-20 Ironwood Pharmaceuticals, Inc. Compositions and methods for treating or preventing metabolic syndrome and related diseases and disorders
US9616097B2 (en) 2010-09-15 2017-04-11 Synergy Pharmaceuticals, Inc. Formulations of guanylate cyclase C agonists and methods of use
CA2828343A1 (en) 2011-03-04 2012-09-13 The Scripps Research Institute Edn3-like peptides and uses thereof
MY188344A (en) 2012-03-09 2021-12-01 Biotropics Malaysia Berhad Extract formulations of rhodamnia cinerea and uses thereof
JP2016514671A (ja) 2013-03-15 2016-05-23 シナジー ファーマシューティカルズ インコーポレイテッド グアニル酸シクラーゼのアゴニストおよびその使用
JP2016514670A (ja) 2013-03-15 2016-05-23 シナジー ファーマシューティカルズ インコーポレイテッド 他の薬物と組み合わせたグアニル酸シクラーゼ受容体アゴニスト
SG11201507496UA (en) 2013-04-17 2015-11-27 Pfizer N-piperidin-3-ylbenzamide derivatives for treating cardiovascular diseases
EA201592263A1 (ru) 2013-06-05 2016-05-31 Синерджи Фармасьютикалз, Инк. Ультрачистые агонисты гуанилатциклазы c, способ их получения и использования
EP3186242B1 (en) 2014-08-29 2021-10-06 Tes Pharma S.r.l. Inhibitors of alpha-amino-beta-carboxymuconic acid semialdehyde decarboxylase
WO2016055901A1 (en) 2014-10-08 2016-04-14 Pfizer Inc. Substituted amide compounds
AU2017342083A1 (en) 2016-10-14 2019-04-11 Tes Pharma S.R.L. Inhibitors of alpha-amino-beta-carboxymuconic acid semialdehyde decarboxylase
AR117122A1 (es) 2018-11-20 2021-07-14 Tes Pharma S R L INHIBIDORES DE LA ÁCIDO a-AMINO-b-CARBOXIMUCÓNICO SEMIALDEHÍDO DESCARBOXILASA
US11248001B2 (en) 2019-01-18 2022-02-15 Astrazeneca Ab PCSK9 inhibitors and methods of use thereof
CN116731091A (zh) * 2022-03-01 2023-09-12 王勇 具有脂肪酶抑制活性的酰基他定类化合物、其制备方法及应用

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4062950A (en) * 1973-09-22 1977-12-13 Bayer Aktiengesellschaft Amino sugar derivatives
DE2347782C3 (de) * 1973-09-22 1979-10-11 Bayer Ag, 5090 Leverkusen Aminozuckerderivate, Verfahren zu ihrer Herstellung sowie diese Verbindungen enthaltende Arzneimittel
US4010258A (en) * 1974-03-15 1977-03-01 Ajinomoto Co., Inc. Microbial amylase inhibitor and preparation thereof with the use of streptomyces diasticus var. amylostaticus
DE2413720C3 (de) * 1974-03-21 1980-03-27 Bayer Ag, 5090 Leverkusen Tierfutter
JPS5154990A (en) * 1974-11-05 1976-05-14 Ajinomoto Kk Amiraazeinhibitaano seizoho
JPS5224119A (en) * 1975-08-20 1977-02-23 Nippon Steel Corp Uniform direct annearing method of wire rod
DE2614393C3 (de) * 1976-04-02 1980-04-03 Bayer Ag, 5090 Leverkusen Aminozucker-Derivate und diese Verbindungen enthaltende Arzneimittel
US4175123A (en) * 1976-12-23 1979-11-20 Bayer Aktiengesellschaft Amino-sugar derivatives, process for their preparation and pharmaceutical composition thereof
DE2719912C3 (de) * 1977-05-04 1979-12-06 Bayer Ag, 5090 Leverkusen Verfahren zur Isolierung von 0- |4,6-Dideoxy-4- [JJl S-O,4,6/5)-4,5,6-trihydroxy-3-hydroxymethyl-2cyclohexen-1-yl] -amino] - a -D-glucopyranosyl} -(I Pfeil nach rechts 4)-0- a D-glucopyranosyl-(l Pfeil nach rechts 4)-D-glucopyranose aus Kulturbrühen

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS62136868U (en:Method) * 1986-02-21 1987-08-28

Also Published As

Publication number Publication date
DE2855409A1 (de) 1979-07-12
GB2011397A (en) 1979-07-11
FR2413401B1 (en:Method) 1982-07-09
GB2011397B (en) 1982-06-23
US4254256A (en) 1981-03-03
JPS5492909A (en) 1979-07-23
FR2413401A1 (fr) 1979-07-27

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