JPS59232094A - 新規な抗腫瘍性抗生物質複合体ｂｂｍ−１６７５ - Google Patents

新規な抗腫瘍性抗生物質複合体ｂｂｍ−１６７５

Info

Publication number
JPS59232094A
JPS59232094A JP59096758A JP9675884A JPS59232094A JP S59232094 A JPS59232094 A JP S59232094A JP 59096758 A JP59096758 A JP 59096758A JP 9675884 A JP9675884 A JP 9675884A JP S59232094 A JPS59232094 A JP S59232094A
Authority
JP
Japan
Prior art keywords
bbm
strain
methanol
actinomadeura
silica gel
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP59096758A
Other languages
English (en)
Japanese (ja)
Other versions
JPH0229079B2 (enExample
Inventor
Masataka Konishi
小西　正隆
Kyoichiro Saito
斉藤　恭一郎
Hiroaki Okuma
大熊　広昭
Hiroshi Kawaguchi
洋 川口
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BRISTOL MAYERS KENKYUSHO KK
Bristol Myers Squibb KK
Original Assignee
BRISTOL MAYERS KENKYUSHO KK
Bristol Myers Squibb KK
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by BRISTOL MAYERS KENKYUSHO KK, Bristol Myers Squibb KK filed Critical BRISTOL MAYERS KENKYUSHO KK
Publication of JPS59232094A publication Critical patent/JPS59232094A/ja
Publication of JPH0229079B2 publication Critical patent/JPH0229079B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P1/00—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
    • C12P1/02—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes by using fungi
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
    • C07H13/08—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals directly attached to carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H11/00—Compounds containing saccharide radicals esterified by inorganic acids; Metal salts thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P1/00—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
    • C12P1/06—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes by using actinomycetales

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Mycology (AREA)
  • General Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
JP59096758A 1983-05-16 1984-05-16 新規な抗腫瘍性抗生物質複合体ｂｂｍ−１６７５ Granted JPS59232094A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US49523183A 1983-05-16 1983-05-16
US495231 1983-05-16

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP1216009A Division JPH02128693A (ja) 1983-05-16 1989-08-24 新規な抗腫瘍性抗生物質複合体ｂｂｍ―１６７５

Publications (2)

Publication Number Publication Date
JPS59232094A true JPS59232094A (ja) 1984-12-26
JPH0229079B2 JPH0229079B2 (enExample) 1990-06-27

Family

ID=23967812

Family Applications (2)

Application Number Title Priority Date Filing Date
JP59096758A Granted JPS59232094A (ja) 1983-05-16 1984-05-16 新規な抗腫瘍性抗生物質複合体ｂｂｍ−１６７５
JP1216009A Granted JPH02128693A (ja) 1983-05-16 1989-08-24 新規な抗腫瘍性抗生物質複合体ｂｂｍ―１６７５

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP1216009A Granted JPH02128693A (ja) 1983-05-16 1989-08-24 新規な抗腫瘍性抗生物質複合体ｂｂｍ―１６７５

Country Status (28)

Country Link
JP (2) JPS59232094A (enExample)
KR (2) KR840008817A (enExample)
AT (1) AT393691B (enExample)
AU (1) AU569294B2 (enExample)
BE (1) BE899667A (enExample)
CA (1) CA1241282A (enExample)
CY (1) CY1465A (enExample)
DE (1) DE3418023A1 (enExample)
DK (1) DK163127C (enExample)
ES (1) ES8700267A1 (enExample)
FI (1) FI81114C (enExample)
FR (1) FR2547594B1 (enExample)
GB (1) GB2141425B (enExample)
GR (1) GR81581B (enExample)
HK (1) HK9889A (enExample)
HU (1) HU193928B (enExample)
IE (1) IE57444B1 (enExample)
IL (1) IL71824A (enExample)
IT (1) IT1175498B (enExample)
KE (1) KE3846A (enExample)
LU (1) LU85362A1 (enExample)
NL (1) NL8401572A (enExample)
NZ (1) NZ208013A (enExample)
PT (1) PT78590A (enExample)
SE (1) SE460364B (enExample)
SU (1) SU1344249A3 (enExample)
YU (1) YU43846B (enExample)
ZA (1) ZA843591B (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GR78648B (enExample) * 1982-07-26 1984-09-27 Bristol Myers Co
IL79519A0 (en) * 1985-08-27 1986-10-31 Bristol Myers Co Bbm-1675c and d antitumor antibiotics
US4837206A (en) * 1987-04-29 1989-06-06 Bristol-Myers Company Esperamicin derivatives
US4996305A (en) * 1988-02-29 1991-02-26 American Cyanamid Company Process for producing the antibiotic and antitumor agents LL-E33288.epsilon.ε-Br
CA2027601A1 (en) * 1989-11-06 1991-05-07 Koko Sugawara Antitumor antibiotic bu-3983t
GB0016020D0 (en) * 2000-06-29 2000-08-23 Inst Biomar Sa New polyciclic xanthones and their use
CA3213700A1 (en) 2021-03-17 2022-09-22 Nissui Corporation Method of purification and purified products

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4195079A (en) * 1979-01-31 1980-03-25 Pfizer Inc. New polycyclic ether antibiotic
JPS56113791A (en) * 1980-02-15 1981-09-07 Kaken Pharmaceut Co Ltd Novel antibiotic and its preparation
GR78648B (enExample) * 1982-07-26 1984-09-27 Bristol Myers Co
US4539203A (en) * 1984-11-13 1985-09-03 Warner-Lambert Company CL-1577D And CL-1577E antibiotic/antitumor compounds, their production and use

Also Published As

Publication number Publication date
DE3418023C2 (enExample) 1988-08-18
GB8412368D0 (en) 1984-06-20
DK239784D0 (da) 1984-05-15
IL71824A (en) 1988-09-30
DK163127C (da) 1992-06-09
IT8420928A1 (it) 1985-11-15
BE899667A (fr) 1984-11-16
GR81581B (enExample) 1984-12-11
YU84984A (en) 1988-04-30
HK9889A (en) 1989-02-10
FR2547594B1 (fr) 1988-03-25
NZ208013A (en) 1987-07-31
FI81114B (fi) 1990-05-31
JPH02128693A (ja) 1990-05-17
KR920001366B1 (ko) 1992-02-11
IT8420928A0 (it) 1984-05-15
AU569294B2 (en) 1988-01-28
AT393691B (de) 1991-11-25
HU193928B (en) 1987-12-28
AU2779184A (en) 1984-11-22
KR840008817A (ko) 1984-12-19
DK163127B (da) 1992-01-20
YU43846B (en) 1989-12-31
IE57444B1 (en) 1992-09-09
HUT37168A (en) 1985-11-28
IL71824A0 (en) 1984-09-30
JPH0229079B2 (enExample) 1990-06-27
ZA843591B (en) 1985-02-27
SE8402619L (sv) 1984-11-17
LU85362A1 (fr) 1985-03-21
FI841906L (fi) 1984-11-17
FI81114C (fi) 1990-09-10
IT1175498B (it) 1987-07-01
KE3846A (en) 1989-04-07
NL8401572A (nl) 1984-12-17
CA1241282A (en) 1988-08-30
KR900019562A (ko) 1990-12-24
FR2547594A1 (fr) 1984-12-21
IE841200L (en) 1984-11-16
ES532476A0 (es) 1986-09-16
GB2141425A (en) 1984-12-19
DK239784A (da) 1984-11-17
GB2141425B (en) 1986-12-03
CY1465A (en) 1989-07-21
ES8700267A1 (es) 1986-09-16
PT78590A (en) 1984-06-01
FI841906A0 (fi) 1984-05-11
SE460364B (sv) 1989-10-02
SE8402619D0 (sv) 1984-05-15
JPH0555111B2 (enExample) 1993-08-16
SU1344249A3 (ru) 1987-10-07
ATA160984A (de) 1991-05-15
DE3418023A1 (de) 1984-11-22

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