BE899667A - Nouveau complexe antibiotique antitumoral dit bbm-1675. - Google Patents

Nouveau complexe antibiotique antitumoral dit bbm-1675.

Info

Publication number
BE899667A
BE899667A BE0/212942A BE212942A BE899667A BE 899667 A BE899667 A BE 899667A BE 0/212942 A BE0/212942 A BE 0/212942A BE 212942 A BE212942 A BE 212942A BE 899667 A BE899667 A BE 899667A
Authority
BE
Belgium
Prior art keywords
bbm
complex
antibiotic complex
antitumor antibiotic
new antitumor
Prior art date
Application number
BE0/212942A
Other languages
English (en)
Inventor
Konishi M
Saitoh K
Ohkuma H
Kawaguchi H
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of BE899667A publication Critical patent/BE899667A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P1/00—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
    • C12P1/02—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes by using fungi
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
    • C07H13/08—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals directly attached to carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H11/00—Compounds containing saccharide radicals esterified by inorganic acids; Metal salts thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P1/00—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
    • C12P1/06—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes by using actinomycetales

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Mycology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Microbiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Nouveau complexe antibiotique dit complexe BBM-1675 qui est obtenu par fermentation de certaines nouvelles souches d'Actionomadura verrucosospora. Le complexe peut etre fractionné en deux composants majeurs, à savoir BBM-1675 A1 et A2, et quatre composants moneurs à savoir BBM-1675 A3, A4, B1 et B2 qui tous manifestent de l'activité antimicrobienne et antitumorale, notamment contre la leucémie P-388. Compositions pharmaceutiques contenant ces composants actifs.
BE0/212942A 1983-05-16 1984-05-15 Nouveau complexe antibiotique antitumoral dit bbm-1675. BE899667A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US49523183A 1983-05-16 1983-05-16

Publications (1)

Publication Number Publication Date
BE899667A true BE899667A (fr) 1984-11-16

Family

ID=23967812

Family Applications (1)

Application Number Title Priority Date Filing Date
BE0/212942A BE899667A (fr) 1983-05-16 1984-05-15 Nouveau complexe antibiotique antitumoral dit bbm-1675.

Country Status (28)

Country Link
JP (2) JPS59232094A (fr)
KR (2) KR840008817A (fr)
AT (1) AT393691B (fr)
AU (1) AU569294B2 (fr)
BE (1) BE899667A (fr)
CA (1) CA1241282A (fr)
CY (1) CY1465A (fr)
DE (1) DE3418023A1 (fr)
DK (1) DK163127C (fr)
ES (1) ES8700267A1 (fr)
FI (1) FI81114C (fr)
FR (1) FR2547594B1 (fr)
GB (1) GB2141425B (fr)
GR (1) GR81581B (fr)
HK (1) HK9889A (fr)
HU (1) HU193928B (fr)
IE (1) IE57444B1 (fr)
IL (1) IL71824A (fr)
IT (1) IT1175498B (fr)
KE (1) KE3846A (fr)
LU (1) LU85362A1 (fr)
NL (1) NL8401572A (fr)
NZ (1) NZ208013A (fr)
PT (1) PT78590A (fr)
SE (1) SE460364B (fr)
SU (1) SU1344249A3 (fr)
YU (1) YU43846B (fr)
ZA (1) ZA843591B (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GR78648B (fr) * 1982-07-26 1984-09-27 Bristol Myers Co
IL79519A0 (en) * 1985-08-27 1986-10-31 Bristol Myers Co Bbm-1675c and d antitumor antibiotics
US4837206A (en) * 1987-04-29 1989-06-06 Bristol-Myers Company Esperamicin derivatives
US4996305A (en) * 1988-02-29 1991-02-26 American Cyanamid Company Process for producing the antibiotic and antitumor agents LL-E33288.epsilon.ε-Br
CA2027601A1 (fr) * 1989-11-06 1991-05-07 Koko Sugawara Antibiotique antitumeur bu-3983t
EP4086621A4 (fr) * 2021-03-17 2024-06-12 Nissui Corporation Procédé de purification et produit purifié

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4195079A (en) * 1979-01-31 1980-03-25 Pfizer Inc. New polycyclic ether antibiotic
JPS56113791A (en) * 1980-02-15 1981-09-07 Kaken Pharmaceut Co Ltd Novel antibiotic and its preparation
GR78648B (fr) * 1982-07-26 1984-09-27 Bristol Myers Co
US4539203A (en) * 1984-11-13 1985-09-03 Warner-Lambert Company CL-1577D And CL-1577E antibiotic/antitumor compounds, their production and use

Also Published As

Publication number Publication date
YU43846B (en) 1989-12-31
DE3418023C2 (fr) 1988-08-18
GB8412368D0 (en) 1984-06-20
SE8402619D0 (sv) 1984-05-15
IL71824A0 (en) 1984-09-30
CA1241282A (fr) 1988-08-30
AT393691B (de) 1991-11-25
AU2779184A (en) 1984-11-22
JPH02128693A (ja) 1990-05-17
KR920001366B1 (ko) 1992-02-11
NZ208013A (en) 1987-07-31
PT78590A (en) 1984-06-01
CY1465A (en) 1989-07-21
FI841906A0 (fi) 1984-05-11
KR840008817A (ko) 1984-12-19
LU85362A1 (fr) 1985-03-21
IT8420928A1 (it) 1985-11-15
IT1175498B (it) 1987-07-01
GB2141425B (en) 1986-12-03
JPS59232094A (ja) 1984-12-26
HU193928B (en) 1987-12-28
KE3846A (en) 1989-04-07
SE460364B (sv) 1989-10-02
DK239784D0 (da) 1984-05-15
YU84984A (en) 1988-04-30
DE3418023A1 (de) 1984-11-22
FI81114B (fi) 1990-05-31
DK163127B (da) 1992-01-20
HUT37168A (en) 1985-11-28
DK163127C (da) 1992-06-09
SE8402619L (sv) 1984-11-17
ES8700267A1 (es) 1986-09-16
NL8401572A (nl) 1984-12-17
ZA843591B (en) 1985-02-27
IT8420928A0 (it) 1984-05-15
GB2141425A (en) 1984-12-19
ATA160984A (de) 1991-05-15
IE841200L (en) 1984-11-16
IE57444B1 (en) 1992-09-09
DK239784A (da) 1984-11-17
JPH0229079B2 (fr) 1990-06-27
SU1344249A3 (ru) 1987-10-07
GR81581B (fr) 1984-12-11
IL71824A (en) 1988-09-30
JPH0555111B2 (fr) 1993-08-16
FR2547594A1 (fr) 1984-12-21
FI841906A (fi) 1984-11-17
HK9889A (en) 1989-02-10
AU569294B2 (en) 1988-01-28
FI81114C (fi) 1990-09-10
FR2547594B1 (fr) 1988-03-25
ES532476A0 (es) 1986-09-16
KR900019562A (ko) 1990-12-24

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Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: BRISTOL-MYERS CY

Effective date: 19960531