SE460364B - Nytt antibiotiskt antitumoerkomplex och foerfarande foer framstaellning daerav - Google Patents

Nytt antibiotiskt antitumoerkomplex och foerfarande foer framstaellning daerav

Info

Publication number
SE460364B
SE460364B SE8402619A SE8402619A SE460364B SE 460364 B SE460364 B SE 460364B SE 8402619 A SE8402619 A SE 8402619A SE 8402619 A SE8402619 A SE 8402619A SE 460364 B SE460364 B SE 460364B
Authority
SE
Sweden
Prior art keywords
bbm
methanol
silica gel
solvent system
volume ratio
Prior art date
Application number
SE8402619A
Other languages
English (en)
Swedish (sv)
Other versions
SE8402619D0 (sv
SE8402619L (sv
Inventor
M Konishi
K Saitoh
H Ohkuma
H Kawaguchi
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of SE8402619D0 publication Critical patent/SE8402619D0/xx
Publication of SE8402619L publication Critical patent/SE8402619L/xx
Publication of SE460364B publication Critical patent/SE460364B/sv

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P1/00Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
    • C12P1/02Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes by using fungi
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/02Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
    • C07H13/08Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals directly attached to carbocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H11/00Compounds containing saccharide radicals esterified by inorganic acids; Metal salts thereof
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P1/00Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
    • C12P1/06Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes by using actinomycetales

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Mycology (AREA)
  • General Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SE8402619A 1983-05-16 1984-05-15 Nytt antibiotiskt antitumoerkomplex och foerfarande foer framstaellning daerav SE460364B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US49523183A 1983-05-16 1983-05-16

Publications (3)

Publication Number Publication Date
SE8402619D0 SE8402619D0 (sv) 1984-05-15
SE8402619L SE8402619L (sv) 1984-11-17
SE460364B true SE460364B (sv) 1989-10-02

Family

ID=23967812

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8402619A SE460364B (sv) 1983-05-16 1984-05-15 Nytt antibiotiskt antitumoerkomplex och foerfarande foer framstaellning daerav

Country Status (28)

Country Link
JP (2) JPS59232094A (fr)
KR (2) KR840008817A (fr)
AT (1) AT393691B (fr)
AU (1) AU569294B2 (fr)
BE (1) BE899667A (fr)
CA (1) CA1241282A (fr)
CY (1) CY1465A (fr)
DE (1) DE3418023A1 (fr)
DK (1) DK163127C (fr)
ES (1) ES8700267A1 (fr)
FI (1) FI81114C (fr)
FR (1) FR2547594B1 (fr)
GB (1) GB2141425B (fr)
GR (1) GR81581B (fr)
HK (1) HK9889A (fr)
HU (1) HU193928B (fr)
IE (1) IE57444B1 (fr)
IL (1) IL71824A (fr)
IT (1) IT1175498B (fr)
KE (1) KE3846A (fr)
LU (1) LU85362A1 (fr)
NL (1) NL8401572A (fr)
NZ (1) NZ208013A (fr)
PT (1) PT78590A (fr)
SE (1) SE460364B (fr)
SU (1) SU1344249A3 (fr)
YU (1) YU43846B (fr)
ZA (1) ZA843591B (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GR78648B (fr) * 1982-07-26 1984-09-27 Bristol Myers Co
IL79519A0 (en) * 1985-08-27 1986-10-31 Bristol Myers Co Bbm-1675c and d antitumor antibiotics
US4837206A (en) * 1987-04-29 1989-06-06 Bristol-Myers Company Esperamicin derivatives
US4996305A (en) * 1988-02-29 1991-02-26 American Cyanamid Company Process for producing the antibiotic and antitumor agents LL-E33288.epsilon.ε-Br
CA2027601A1 (fr) * 1989-11-06 1991-05-07 Koko Sugawara Antibiotique antitumeur bu-3983t
US20240075407A1 (en) * 2021-03-17 2024-03-07 Nissui Corporation Method of purification and purified products

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4195079A (en) * 1979-01-31 1980-03-25 Pfizer Inc. New polycyclic ether antibiotic
JPS56113791A (en) * 1980-02-15 1981-09-07 Kaken Pharmaceut Co Ltd Novel antibiotic and its preparation
GR78648B (fr) * 1982-07-26 1984-09-27 Bristol Myers Co
US4539203A (en) * 1984-11-13 1985-09-03 Warner-Lambert Company CL-1577D And CL-1577E antibiotic/antitumor compounds, their production and use

Also Published As

Publication number Publication date
GB8412368D0 (en) 1984-06-20
SE8402619D0 (sv) 1984-05-15
GR81581B (fr) 1984-12-11
IT1175498B (it) 1987-07-01
DK163127C (da) 1992-06-09
LU85362A1 (fr) 1985-03-21
ZA843591B (en) 1985-02-27
NZ208013A (en) 1987-07-31
AT393691B (de) 1991-11-25
JPH02128693A (ja) 1990-05-17
GB2141425B (en) 1986-12-03
IT8420928A1 (it) 1985-11-15
FI841906A (fi) 1984-11-17
HUT37168A (en) 1985-11-28
FI841906A0 (fi) 1984-05-11
KR920001366B1 (ko) 1992-02-11
SE8402619L (sv) 1984-11-17
GB2141425A (en) 1984-12-19
DK239784D0 (da) 1984-05-15
ATA160984A (de) 1991-05-15
CY1465A (en) 1989-07-21
FR2547594B1 (fr) 1988-03-25
KE3846A (en) 1989-04-07
HU193928B (en) 1987-12-28
IL71824A0 (en) 1984-09-30
AU569294B2 (en) 1988-01-28
YU84984A (en) 1988-04-30
AU2779184A (en) 1984-11-22
IE841200L (en) 1984-11-16
ES8700267A1 (es) 1986-09-16
DK163127B (da) 1992-01-20
FR2547594A1 (fr) 1984-12-21
DE3418023C2 (fr) 1988-08-18
FI81114C (fi) 1990-09-10
SU1344249A3 (ru) 1987-10-07
JPH0555111B2 (fr) 1993-08-16
CA1241282A (fr) 1988-08-30
JPH0229079B2 (fr) 1990-06-27
YU43846B (en) 1989-12-31
NL8401572A (nl) 1984-12-17
ES532476A0 (es) 1986-09-16
HK9889A (en) 1989-02-10
JPS59232094A (ja) 1984-12-26
IE57444B1 (en) 1992-09-09
FI81114B (fi) 1990-05-31
DK239784A (da) 1984-11-17
DE3418023A1 (de) 1984-11-22
IL71824A (en) 1988-09-30
BE899667A (fr) 1984-11-16
KR840008817A (ko) 1984-12-19
KR900019562A (ko) 1990-12-24
PT78590A (en) 1984-06-01
IT8420928A0 (it) 1984-05-15

Similar Documents

Publication Publication Date Title
US4675187A (en) BBM-1675, a new antibiotic complex
US4918174A (en) Tiacumicin compounds
EP0132082B1 (fr) Composés antibiotiques/antitumoraux et leur production
US4518589A (en) BBM-2478 Antibiotic complex
GB2164035A (en) A novel antibiotic and production thereof
US4567143A (en) Process for preparing 4'-deschlororebeccamycin
CA1230568A (fr) Antibiotique antitumoral
SE460364B (sv) Nytt antibiotiskt antitumoerkomplex och foerfarande foer framstaellning daerav
US4916065A (en) BU-3420T Antitumor antibiotic
US5494820A (en) Streptomyces braegensis strain and its cultivation in a process for producing C9 -desoxo-FK-520
US4708872A (en) Antitumor antibiotic complex
US4598145A (en) Albacarcins V and M
US4360595A (en) Fermentation process for producing anandimycin
US4868117A (en) BBM-1675, a new antitumor antibiotic complex
US4626503A (en) Antitumor agents LL-D49194α1, LL-D49194β1, LL-D49194β2, LL-D49194β3, LL-D49194γ, LL-D49194δ, LL-D49194ε, LL-D49194ξ, LL-D49194η, LL-D49194ω1, LL-D49194ω2, and LL-D49194ω3
US4301248A (en) Fermentation process for making rachelmycin
US4572895A (en) Process for preparing an antibiotic complex by culturing actinomyces strain ATCC 39417
US4599310A (en) Process for producing antitumor antibiotic compound
US4835141A (en) Neutral macrolide antibiotics from Streptomyces
EP0157203A2 (fr) Agents antitumoraux LL-D49194 alpha 1, LL-D49194 bêta 1, LL-D49194 bêta 2, LL-D49194 bêta 3, LL-D49194 gamma, LL-D49194 delta, LL-D49194 epsilon, LL-D49194 dzéta, LL-D49194 êta LL-D499194 oméga 1, LL-D49194 oméga 2 et LL-D49194 oméga 3
US4112071A (en) Antibiotic complex
US5116845A (en) BU-3420T antitumor antibiotic
US4952572A (en) BU-3420T antifungal antibiotic
EP0025713B1 (fr) Antibiotique de la série de l'anthracycline et composition pharmaceutique le contenant
EP0094176A1 (fr) Antibiotiques macrolides à partir de streptomyces

Legal Events

Date Code Title Description
NAL Patent in force

Ref document number: 8402619-4

Format of ref document f/p: F

NUG Patent has lapsed

Ref document number: 8402619-4

Format of ref document f/p: F