JPS59212482A - チアゾ−ル類の合成 - Google Patents

チアゾ−ル類の合成

Info

Publication number
JPS59212482A
JPS59212482A JP59093825A JP9382584A JPS59212482A JP S59212482 A JPS59212482 A JP S59212482A JP 59093825 A JP59093825 A JP 59093825A JP 9382584 A JP9382584 A JP 9382584A JP S59212482 A JPS59212482 A JP S59212482A
Authority
JP
Japan
Prior art keywords
formula
represented
product
added
methyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP59093825A
Other languages
English (en)
Japanese (ja)
Other versions
JPH0579672B2 (enExample
Inventor
ジフオ−ド・ピ−・マルツオ−ニ
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23962095&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=JPS59212482(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Publication of JPS59212482A publication Critical patent/JPS59212482A/ja
Publication of JPH0579672B2 publication Critical patent/JPH0579672B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D277/28—Radicals substituted by nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/08—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D277/12—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/14—Oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Catalysts (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
JP59093825A 1983-05-12 1984-05-09 チアゾ−ル類の合成 Granted JPS59212482A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/493,883 US4468517A (en) 1983-05-12 1983-05-12 Synthesis of thiazoles
US493,883 1983-05-12

Publications (2)

Publication Number Publication Date
JPS59212482A true JPS59212482A (ja) 1984-12-01
JPH0579672B2 JPH0579672B2 (enExample) 1993-11-04

Family

ID=23962095

Family Applications (1)

Application Number Title Priority Date Filing Date
JP59093825A Granted JPS59212482A (ja) 1983-05-12 1984-05-09 チアゾ−ル類の合成

Country Status (12)

Country Link
US (1) US4468517A (enExample)
EP (1) EP0125887B1 (enExample)
JP (1) JPS59212482A (enExample)
KR (1) KR860001510B1 (enExample)
CA (1) CA1217486A (enExample)
DE (1) DE3461638D1 (enExample)
DK (1) DK161142C (enExample)
GB (1) GB2140802B (enExample)
GR (1) GR82074B (enExample)
HU (1) HU189111B (enExample)
IE (1) IE57395B1 (enExample)
IL (1) IL71786A (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4917243B2 (ja) * 2001-05-23 2012-04-18 日本曹達株式会社 チアゾール化合物の製造方法

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0515121B1 (en) * 1991-05-21 2000-11-02 Eli Lilly And Company Process for preparing intermediates to nizatidine and related compounds
US5541335A (en) * 1994-07-11 1996-07-30 Torcan Chemical Ltd. Process for preparing nizatidine
WO2004069817A1 (en) * 2003-02-10 2004-08-19 Kumar Dinesh R An improved process for preparing nizatidine intermediate
CN106279060A (zh) * 2016-08-10 2017-01-04 四川摩尔生物制药有限公司 尼扎替丁原料药的制备方法

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4848466A (enExample) * 1971-10-18 1973-07-09
JPS5791980A (en) * 1980-10-02 1982-06-08 Lilly Co Eli 2,4-disubstituted thiazole derivatives

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3391151A (en) * 1966-05-23 1968-07-02 American Home Prod Benzhydrylthiazole derivatives

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4848466A (enExample) * 1971-10-18 1973-07-09
JPS5791980A (en) * 1980-10-02 1982-06-08 Lilly Co Eli 2,4-disubstituted thiazole derivatives

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4917243B2 (ja) * 2001-05-23 2012-04-18 日本曹達株式会社 チアゾール化合物の製造方法

Also Published As

Publication number Publication date
HUT36104A (en) 1985-08-28
GB2140802B (en) 1986-10-15
IL71786A (en) 1987-10-20
JPH0579672B2 (enExample) 1993-11-04
IL71786A0 (en) 1984-09-30
IE841161L (en) 1984-11-12
KR860001510B1 (ko) 1986-09-30
DK232184A (da) 1984-11-13
DK161142B (da) 1991-06-03
EP0125887A1 (en) 1984-11-21
KR840008800A (ko) 1984-12-19
DK232184D0 (da) 1984-05-10
EP0125887B1 (en) 1986-12-10
IE57395B1 (en) 1992-08-26
GB2140802A (en) 1984-12-05
US4468517A (en) 1984-08-28
CA1217486A (en) 1987-02-03
DK161142C (da) 1991-11-18
GR82074B (enExample) 1984-12-13
DE3461638D1 (en) 1987-01-22
GB8411887D0 (en) 1984-06-13
HU189111B (en) 1986-06-30

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Legal Events

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