JPS59161379A - γ−ブチロラクトン誘導体、その製造方法及びそれを含有する薬剤 - Google Patents

γ−ブチロラクトン誘導体、その製造方法及びそれを含有する薬剤

Info

Publication number
JPS59161379A
JPS59161379A JP58209771A JP20977183A JPS59161379A JP S59161379 A JPS59161379 A JP S59161379A JP 58209771 A JP58209771 A JP 58209771A JP 20977183 A JP20977183 A JP 20977183A JP S59161379 A JPS59161379 A JP S59161379A
Authority
JP
Japan
Prior art keywords
group
compound
mixture
solvent
ether
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP58209771A
Other languages
English (en)
Japanese (ja)
Inventor
クロ−ド・ベルナ−ル
ベルナ−・カウトレ−ルズ
パトリツク・ゴテイエ
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi SA
Original Assignee
Sanofi SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi SA filed Critical Sanofi SA
Publication of JPS59161379A publication Critical patent/JPS59161379A/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/57—Nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Furan Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
JP58209771A 1982-11-08 1983-11-08 γ−ブチロラクトン誘導体、その製造方法及びそれを含有する薬剤 Pending JPS59161379A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8218705 1982-11-08
FR8218705A FR2535722B1 (fr) 1982-11-08 1982-11-08 Derives de la g-butyrolactone protecteurs du myocarde presentant une activite antiarythmique, procede pour leur preparation et medicaments en contenant

Publications (1)

Publication Number Publication Date
JPS59161379A true JPS59161379A (ja) 1984-09-12

Family

ID=9278999

Family Applications (1)

Application Number Title Priority Date Filing Date
JP58209771A Pending JPS59161379A (ja) 1982-11-08 1983-11-08 γ−ブチロラクトン誘導体、その製造方法及びそれを含有する薬剤

Country Status (29)

Country Link
US (1) US4542134A (enExample)
EP (1) EP0113600B1 (enExample)
JP (1) JPS59161379A (enExample)
KR (1) KR900006723B1 (enExample)
AT (1) ATE28644T1 (enExample)
AU (1) AU560032B2 (enExample)
CA (1) CA1224467A (enExample)
CS (1) CS244680B2 (enExample)
DD (2) DD231567A5 (enExample)
DE (1) DE3372767D1 (enExample)
DK (1) DK503683A (enExample)
ES (1) ES8406071A1 (enExample)
FI (1) FI79538C (enExample)
FR (1) FR2535722B1 (enExample)
GR (1) GR78746B (enExample)
HU (1) HU192825B (enExample)
IE (1) IE56208B1 (enExample)
IL (1) IL70062A (enExample)
MA (1) MA19947A1 (enExample)
NO (1) NO159853C (enExample)
NZ (1) NZ206176A (enExample)
OA (1) OA07581A (enExample)
PH (1) PH19547A (enExample)
PL (2) PL142949B1 (enExample)
PT (1) PT77606B (enExample)
SG (1) SG2389G (enExample)
SU (1) SU1279529A1 (enExample)
YU (2) YU220483A (enExample)
ZA (1) ZA837935B (enExample)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3714173A (en) * 1971-07-06 1973-01-30 Smith Kline French Lab Pyridyl ketipate lactones and derivatives
FR2467200A1 (fr) * 1979-10-11 1981-04-17 Clin Midy Derives du pyrrole actifs sur les troubles du rythme cardiovasculaire

Also Published As

Publication number Publication date
PH19547A (en) 1986-05-20
SU1279529A3 (ru) 1986-12-23
FI834069A0 (fi) 1983-11-07
AU2063983A (en) 1984-05-17
DD231567A5 (de) 1986-01-02
NZ206176A (en) 1985-12-13
PT77606A (fr) 1983-12-01
ES527092A0 (es) 1984-07-01
DD220313A5 (de) 1985-03-27
PT77606B (fr) 1986-03-18
AU560032B2 (en) 1987-03-26
DE3372767D1 (en) 1987-09-03
FI834069L (fi) 1984-05-09
EP0113600B1 (fr) 1987-07-29
FR2535722A1 (fr) 1984-05-11
OA07581A (fr) 1985-03-31
FI79538B (fi) 1989-09-29
CS244680B2 (en) 1986-08-14
FR2535722B1 (fr) 1985-06-28
HU192825B (en) 1987-07-28
NO834053L (no) 1984-05-09
NO159853B (no) 1988-11-07
PL139945B1 (en) 1987-03-31
IL70062A (en) 1987-02-27
PL142949B1 (en) 1987-12-31
SG2389G (en) 1991-01-04
ZA837935B (en) 1984-06-27
YU220483A (en) 1986-04-30
IL70062A0 (en) 1984-01-31
SU1279529A1 (ru) 1986-12-23
ES8406071A1 (es) 1984-07-01
IE56208B1 (en) 1991-05-22
CA1224467A (en) 1987-07-21
MA19947A1 (fr) 1984-07-01
US4542134A (en) 1985-09-17
DK503683A (da) 1984-05-09
CS821983A2 (en) 1985-10-16
ATE28644T1 (de) 1987-08-15
GR78746B (enExample) 1984-10-02
YU143585A (en) 1986-04-30
KR840006646A (ko) 1984-12-01
FI79538C (fi) 1990-01-10
PL249775A1 (en) 1985-05-07
PL244461A1 (en) 1985-01-30
KR900006723B1 (ko) 1990-09-20
IE832580L (en) 1984-05-08
DK503683D0 (da) 1983-11-03
EP0113600A1 (fr) 1984-07-18
NO159853C (no) 1989-02-15

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