JPS5883661A - ベンジルアルコ−ル誘導体の製法 - Google Patents

ベンジルアルコ−ル誘導体の製法

Info

Publication number
JPS5883661A
JPS5883661A JP56181951A JP18195181A JPS5883661A JP S5883661 A JPS5883661 A JP S5883661A JP 56181951 A JP56181951 A JP 56181951A JP 18195181 A JP18195181 A JP 18195181A JP S5883661 A JPS5883661 A JP S5883661A
Authority
JP
Japan
Prior art keywords
group
compound
reaction
general formula
derivative
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP56181951A
Other languages
English (en)
Japanese (ja)
Other versions
JPS6121620B2 (en:Method
Inventor
Ikuo Iijima
飯島　郁夫
Akio Nakao
中尾　明夫
Mitsunori Gaino
我伊野　三徳
Atsuo Oishi
大石　篤郎
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Tanabe Pharma Corp
Original Assignee
Tanabe Seiyaku Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tanabe Seiyaku Co Ltd filed Critical Tanabe Seiyaku Co Ltd
Priority to JP56181951A priority Critical patent/JPS5883661A/ja
Priority to CA000415011A priority patent/CA1196342A/en
Priority to CH6482/82A priority patent/CH650247A5/de
Priority to SE8206352A priority patent/SE454775B/sv
Priority to ES517297A priority patent/ES8401013A1/es
Priority to DK502682A priority patent/DK163660C/da
Priority to KR828205098A priority patent/KR870000471B1/ko
Priority to AT0409882A priority patent/AT382866B/de
Priority to IT68332/82A priority patent/IT1191227B/it
Priority to HU823632A priority patent/HU189190B/hu
Publication of JPS5883661A publication Critical patent/JPS5883661A/ja
Publication of JPS6121620B2 publication Critical patent/JPS6121620B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/46—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C215/56—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains further substituted by hydroxy groups
    • C07C215/58—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains further substituted by hydroxy groups with hydroxy groups and the six-membered aromatic ring, or the condensed ring system containing that ring, bound to the same carbon atom of the carbon chain
    • C07C215/60—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains further substituted by hydroxy groups with hydroxy groups and the six-membered aromatic ring, or the condensed ring system containing that ring, bound to the same carbon atom of the carbon chain the chain having two carbon atoms between the amino groups and the six-membered aromatic ring or the condensed ring system containing that ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C213/08—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions not involving the formation of amino groups, hydroxy groups or etherified or esterified hydroxy groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/075—Ethers or acetals
    • A61K31/085—Ethers or acetals having an ether linkage to aromatic ring nuclear carbon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C1/00—Preparation of hydrocarbons from one or more compounds, none of them being a hydrocarbon
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C213/02—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions involving the formation of amino groups from compounds containing hydroxy groups or etherified or esterified hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C213/10—Separation; Purification; Stabilisation; Use of additives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/54—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C217/56—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by singly-bound oxygen atoms
    • C07C217/60—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by singly-bound oxygen atoms linked by carbon chains having two carbon atoms between the amino groups and the six-membered aromatic ring or the condensed ring system containing that ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/54—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C217/64—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains further substituted by singly-bound oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/54—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C217/64—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains further substituted by singly-bound oxygen atoms
    • C07C217/66—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains further substituted by singly-bound oxygen atoms with singly-bound oxygen atoms and six-membered aromatic rings bound to the same carbon atom of the carbon chain
    • C07C217/70—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains further substituted by singly-bound oxygen atoms with singly-bound oxygen atoms and six-membered aromatic rings bound to the same carbon atom of the carbon chain linked by carbon chains having two carbon atoms between the amino groups and the six-membered aromatic ring or the condensed ring system containing that ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
    • C07C235/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C235/32—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
    • C07C235/34—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/02—Ethers
    • C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
    • C07C43/23—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring containing hydroxy or O-metal groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP56181951A 1981-11-12 1981-11-12 ベンジルアルコ−ル誘導体の製法 Granted JPS5883661A (ja)

Priority Applications (10)

Application Number Priority Date Filing Date Title
JP56181951A JPS5883661A (ja) 1981-11-12 1981-11-12 ベンジルアルコ−ル誘導体の製法
CA000415011A CA1196342A (en) 1981-11-12 1982-11-05 Process for preparing benzylalcohol derivatives
CH6482/82A CH650247A5 (en) 1981-11-12 1982-11-08 Process for preparing benzyl alcohol derivatives
SE8206352A SE454775B (sv) 1981-11-12 1982-11-09 Sett att framstella bensylalkoholderivat
ES517297A ES8401013A1 (es) 1981-11-12 1982-11-11 Un procedimiento para la preparacion de un derivado de alcohol bencilico.
DK502682A DK163660C (da) 1981-11-12 1982-11-11 Fremgangsmaade til fremstilling af benzylalkoholderivater eller farmaceutisk acceptable syreadditionssalte deraf
KR828205098A KR870000471B1 (ko) 1981-11-12 1982-11-11 벤질알콜 유도체의 제조방법
AT0409882A AT382866B (de) 1981-11-12 1982-11-11 Verfahren zur herstellung von benzylalkoholderivaten und ihren salzen
IT68332/82A IT1191227B (it) 1981-11-12 1982-11-11 Procedimento per la preparazione di derivati dell'alcool benzilico
HU823632A HU189190B (en) 1981-11-12 1982-11-11 Process for preparing benzylalcohole derivatives

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP56181951A JPS5883661A (ja) 1981-11-12 1981-11-12 ベンジルアルコ−ル誘導体の製法

Publications (2)

Publication Number Publication Date
JPS5883661A true JPS5883661A (ja) 1983-05-19
JPS6121620B2 JPS6121620B2 (en:Method) 1986-05-28

Family

ID=16109721

Family Applications (1)

Application Number Title Priority Date Filing Date
JP56181951A Granted JPS5883661A (ja) 1981-11-12 1981-11-12 ベンジルアルコ−ル誘導体の製法

Country Status (10)

Country Link
JP (1) JPS5883661A (en:Method)
KR (1) KR870000471B1 (en:Method)
AT (1) AT382866B (en:Method)
CA (1) CA1196342A (en:Method)
CH (1) CH650247A5 (en:Method)
DK (1) DK163660C (en:Method)
ES (1) ES8401013A1 (en:Method)
HU (1) HU189190B (en:Method)
IT (1) IT1191227B (en:Method)
SE (1) SE454775B (en:Method)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4579972A (en) * 1983-04-28 1986-04-01 Smithkline Beckman Corporation Intermediates for preparing secondary amines

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0735693U (ja) * 1993-12-14 1995-07-04 協和電機化学株式会社 ガラス扉の突き合わせ部密封用シール
US7985168B2 (en) 2009-03-25 2011-07-26 Graa Innovations, Llc Power stride apparatus and method of training therefor

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5310974B2 (en:Method) * 1974-06-10 1978-04-18
JPS6241829Y2 (en:Method) * 1980-03-28 1987-10-26

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4579972A (en) * 1983-04-28 1986-04-01 Smithkline Beckman Corporation Intermediates for preparing secondary amines

Also Published As

Publication number Publication date
SE454775B (sv) 1988-05-30
ES517297A0 (es) 1983-12-01
SE8206352D0 (sv) 1982-11-09
DK502682A (da) 1983-05-13
KR870000471B1 (ko) 1987-03-11
SE8206352L (sv) 1983-05-13
ES8401013A1 (es) 1983-12-01
HU189190B (en) 1986-06-30
JPS6121620B2 (en:Method) 1986-05-28
IT1191227B (it) 1988-02-24
CH650247A5 (en) 1985-07-15
DK163660B (da) 1992-03-23
DK163660C (da) 1992-08-17
CA1196342A (en) 1985-11-05
IT8268332A0 (it) 1982-11-11
KR840002343A (ko) 1984-06-25
AT382866B (de) 1987-04-27
ATA409882A (de) 1986-09-15

Similar Documents

Publication Publication Date Title
NO167947B (no) Lagringsanordning for baand- eller plate-registreringsmedier
JPS62238236A (ja) アルコキシサリチル酸誘導体の製造方法
JPS6126538B2 (en:Method)
US2370592A (en) Sulphauro compounds and processes for their production
US2403776A (en) Preparation of 2-(n4-acylsulphanilamido) pyrazine
JPS6121620B2 (en:Method)
McDowell et al. Elimination–addition. Part XI. Electronic effects upon the reactivity of aryl vinyl sulphones towards amines
RU2242467C2 (ru) Способ получения производных тиобарбитуровой кислоты
Kumar et al. Cu (OAc) 2-Promoted Thiolation and Selenylation of C (sp2)-H Bonds Using a 2-Amino Oxazole Directing Group
SMITH et al. Convenient Syntheses of 1, 2, 3, 4-Tetrahydroquinoxalines
US5723622A (en) Synthetic method for making pyridin-propyl-sulphobetaine without any risks for the human beings and the environment
US2506019A (en) Carboxyphenylamino-amino-diphenyl sulfide and preparation thereof
SU561513A3 (ru) Способ получени производных пиперазина или их солей
JPS61227563A (ja) トルメチンの製法
O'Connor et al. An improved synthesis of 1-picryl-2, 2-diphenylhydrazyl radical. Purification and storage of 1, 1-diphenylhydrazine as the tosylate salt
US4294970A (en) Oxidation of alpha-alkylated, benzyl-substituted 2-thiopyridine 1-oxides
JPS6233148A (ja) ベンゼンスルホニルクロリド誘導体の製造方法
JPH04305572A (ja) カルボキシル基を有する環状アミン化合物
US3541158A (en) 1-(di(lower alkoxy)-4-alkylphenyl)-2-nitropropenes
JPH0235755B2 (ja) Benzochiazorinonkagobutsunoseiho
SU615065A1 (ru) Способ получени моносульфонилтиомочевин
SU726089A1 (ru) Способ получени аралкилалкилсульфидов
CN120698910A (zh) Elobixibat中间体2,4-二溴-5-甲氧基苯磺酰氯的制备方法
US2221915A (en) Process for the manufacture of aminoaryl sulphones
US4978796A (en) N-alkylpyrrolidone solvents for preparation of aromatic thiols