JPS5854122B2 - 新規なエルゴットアルカロイド薬剤およびその製法 - Google Patents
新規なエルゴットアルカロイド薬剤およびその製法Info
- Publication number
- JPS5854122B2 JPS5854122B2 JP51123463A JP12346376A JPS5854122B2 JP S5854122 B2 JPS5854122 B2 JP S5854122B2 JP 51123463 A JP51123463 A JP 51123463A JP 12346376 A JP12346376 A JP 12346376A JP S5854122 B2 JPS5854122 B2 JP S5854122B2
- Authority
- JP
- Japan
- Prior art keywords
- polymer
- drug according
- item
- drug
- solid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/48—Ergoline derivatives, e.g. lysergic acid, ergotamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Neurosurgery (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE2546577A DE2546577B2 (de) | 1975-10-17 | 1975-10-17 | Feste Stoffe aus Polyvinylpyrrolidon und Ergotalkaloiden |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS5251014A JPS5251014A (en) | 1977-04-23 |
JPS5854122B2 true JPS5854122B2 (ja) | 1983-12-02 |
Family
ID=5959411
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP51123463A Expired JPS5854122B2 (ja) | 1975-10-17 | 1976-10-16 | 新規なエルゴットアルカロイド薬剤およびその製法 |
Country Status (28)
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1572226A (en) * | 1977-11-03 | 1980-07-30 | Hoechst Uk Ltd | Pharmaceutical preparations in solid unit dosage form |
DK154607C (da) * | 1978-12-21 | 1989-06-05 | Sandoz Ag | Fremgangsmaade til fremstilling af en laegemiddelform til oral administration af ergotalkaloider |
US4411882A (en) | 1978-12-21 | 1983-10-25 | Sandoz Ltd. | Galenical compositions |
FR2454804B1 (fr) * | 1979-04-26 | 1986-11-21 | Sanofi Sa | Medicament a base de dihydroergotoxine et son procede de preparation |
US4366145A (en) * | 1981-06-24 | 1982-12-28 | Sandoz, Inc. | Soft gelatin capsule with a liquid ergot alkaloid center fill solution and method of preparation |
US4898729A (en) * | 1983-12-09 | 1990-02-06 | Euroceltique, S.A. | Treatment of hypertension, compounds and compositions for antihypertension and diuresis |
NL194389C (nl) * | 1984-06-14 | 2002-03-04 | Novartis Ag | Werkwijze voor het bereiden van een vaste dispersie van een farmaceutisch actief middel dat een lage oplosbaarheid in water heeft, in een vaste matrix van een in water oplosbaar polyalkyleenglycol als drager. |
EP0277092B1 (de) * | 1987-01-14 | 1992-01-29 | Ciba-Geigy Ag | Therapeutisches System für schwerlösliche Wirkstoffe |
FR2610827B1 (fr) * | 1987-02-18 | 1991-09-13 | Pf Medicament | Comprime de dihydroergotamine (d.h.e.) du type a matrice hydrophile et son procede de fabrication |
US5064656A (en) * | 1989-11-14 | 1991-11-12 | Dr. Gergely & Co. | Uncoated pharmaceutical reaction tablet |
DE4401646A1 (de) * | 1994-01-21 | 1995-07-27 | Krewel Werke Gmbh | Optimal freisetzende Kava-Extrakte |
US6524832B1 (en) | 1994-02-04 | 2003-02-25 | Arch Development Corporation | DNA damaging agents in combination with tyrosine kinase inhibitors |
ZA9811592B (en) * | 1997-12-22 | 1999-06-17 | Schering Corp | Molecular dispersion composition with enhanced bioavailability |
US6632455B2 (en) | 1997-12-22 | 2003-10-14 | Schering Corporation | Molecular dispersion composition with enhanced bioavailability |
US6316462B1 (en) | 1999-04-09 | 2001-11-13 | Schering Corporation | Methods of inducing cancer cell death and tumor regression |
EP1235574B1 (en) * | 1999-12-03 | 2005-02-02 | Polichem S.A. | Methods for making sustained-release pharmaceutical compositions of ergot alkaloids having improved bioavailability and compositions thereof |
US7771746B2 (en) | 1999-12-03 | 2010-08-10 | Polichem Sa | Methods for making sustained-release pharmaceutical compositions of ergot alkaloids having improved bioavailability and compositions thereof |
US7135436B2 (en) | 2003-05-05 | 2006-11-14 | J.F. Daley International, Ltd. | Solid algicide, preparation and usage in recirculating water |
AU2003304242A1 (en) * | 2003-06-27 | 2005-01-13 | Bioprogress S.P.A. | Composite product obtainable by cogrinding of a active principle with a copolymer n-vinyl-2-pyrrolidone/vinyl-acetate |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1175430A (en) * | 1966-04-07 | 1969-12-23 | Sandoz Ltd | Pharmaceutical Compositions containing Ergot Alkaloids |
-
1975
- 1975-10-17 DE DE2546577A patent/DE2546577B2/de not_active Withdrawn
-
1976
- 1976-10-01 CH CH1244876A patent/CH643737A5/de not_active IP Right Cessation
- 1976-10-08 FI FI762875A patent/FI762875A/fi not_active Application Discontinuation
- 1976-10-08 DK DK454176A patent/DK146194C/da not_active IP Right Cessation
- 1976-10-08 NO NO763446A patent/NO144468C/no unknown
- 1976-10-08 SE SE7611189A patent/SE430379B/xx not_active IP Right Cessation
- 1976-10-13 NL NLAANVRAGE7611295,A patent/NL184558C/xx not_active IP Right Cessation
- 1976-10-14 FR FR7630866A patent/FR2327764A1/fr active Granted
- 1976-10-14 PH PH19008A patent/PH14513A/en unknown
- 1976-10-14 CA CA263,423A patent/CA1079641A/en not_active Expired
- 1976-10-15 GB GB42907/76A patent/GB1560406A/en not_active Expired
- 1976-10-15 SU SU762412401A patent/SU1165223A3/ru active
- 1976-10-15 IE IE2282/76A patent/IE43778B1/en not_active IP Right Cessation
- 1976-10-15 ES ES452420A patent/ES452420A1/es not_active Expired
- 1976-10-15 AT AT767976A patent/AT362510B/de not_active IP Right Cessation
- 1976-10-15 AU AU18754/76A patent/AU508628B2/en not_active Expired
- 1976-10-15 IL IL50686A patent/IL50686A/xx unknown
- 1976-10-15 BE BE171578A patent/BE847368A/xx not_active IP Right Cessation
- 1976-10-15 ZA ZA00766166A patent/ZA766166B/xx unknown
- 1976-10-15 CS CS766685A patent/CS199647B2/cs unknown
- 1976-10-15 NZ NZ182341A patent/NZ182341A/xx unknown
- 1976-10-15 PT PT65719A patent/PT65719B/pt unknown
- 1976-10-15 HU HU76SA00002985A patent/HU172533B/hu not_active IP Right Cessation
- 1976-10-16 JP JP51123463A patent/JPS5854122B2/ja not_active Expired
- 1976-10-16 GR GR51952A patent/GR61268B/el unknown
-
1982
- 1982-12-23 SG SG630/82A patent/SG63082G/en unknown
-
1983
- 1983-01-20 HK HK31/83A patent/HK3183A/xx unknown
-
1984
- 1984-12-30 MY MY63/84A patent/MY8400063A/xx unknown
Non-Patent Citations (2)
Title |
---|
JOURNAL PHARM ACEUTICAL SCIENCE=1966 * |
THE MERCK TRDEX * |
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
JPS5854122B2 (ja) | 新規なエルゴットアルカロイド薬剤およびその製法 | |
AU2002222567B2 (en) | Composition improved in solubility or oral absorbability | |
KR101301548B1 (ko) | 7-〔(e)-t-부틸옥시미노메틸〕 캄토테신의 향상된경구 흡수를 위한 즉시방출 치료 시스템 | |
JP2010509289A (ja) | チロシンキナーゼ阻害剤の経口投与用薬学的剤形 | |
PL185604B1 (pl) | Preparat farmaceutyczny zawierający bromowodorek darifenacyny | |
OA11518A (en) | Novel process for manufacturing paroxitine solid dispersions. | |
JPS5925316A (ja) | 作用時間の長いスロ−・リリ−ズ薬剤組成物及びその製法 | |
JPH01308231A (ja) | 安定化された医薬組成物および製造法 | |
CA1146545A (en) | Pharmaceutical composition comprising bencyclane fumarate and cyclodextrin | |
JP2023058627A (ja) | デュタステリドを含む固形製剤およびその製造方法 | |
JPH0769874A (ja) | カプセル形態のユビデカレノン経口製剤 | |
KR101538985B1 (ko) | 타다라필 구강붕해필름 및 이의 제조방법 | |
US3673163A (en) | Pharmacological preparation containing an acronycine-polyvinylprrolidone coprecipitate | |
JPS60181017A (ja) | Map固体状製剤およびその製造方法 | |
JPH0361644B2 (US20110158925A1-20110630-C00042.png) | ||
CN104510707A (zh) | 一种泊沙康唑固体分散体及其制备方法 | |
JP2009506027A (ja) | 初期溶解率が改善されたプランルカスト固体分散体の薬剤学的組成物およびその製造方法 | |
WO2003086405A1 (fr) | Composition de dispersion solide | |
JP2008518909A (ja) | 非水性極性溶媒中の10−ヒドロキシカンプトテシン化合物の溶解度を増加させるための薬剤製剤 | |
KR20100047230A (ko) | 수용성 빈플루닌 염의 안정적인 약학적 조성물 | |
KR102294171B1 (ko) | 난용성 약물의 가용화제를 이용한 고체분산체 제조 | |
KR0172134B1 (ko) | 고형 제제 | |
WO2023074785A1 (ja) | シロップ剤 | |
KR100561318B1 (ko) | 아테놀올을 함유하는 투명 연질 캡슐 | |
KR100201907B1 (ko) | 비페닐디메틸디카르복실레이트를 가용화시킨 연질캅셀제 |