JPS5762288A - Novel oxime derivative of 7-aminothiazolylacetamidocephalosporanic acid, manufacture and pharmaceutical composition - Google Patents

Novel oxime derivative of 7-aminothiazolylacetamidocephalosporanic acid, manufacture and pharmaceutical composition

Info

Publication number
JPS5762288A
JPS5762288A JP56119432A JP11943281A JPS5762288A JP S5762288 A JPS5762288 A JP S5762288A JP 56119432 A JP56119432 A JP 56119432A JP 11943281 A JP11943281 A JP 11943281A JP S5762288 A JPS5762288 A JP S5762288A
Authority
JP
Japan
Prior art keywords
manufacture
pharmaceutical composition
oxime derivative
novel oxime
aminothiazolylacetamidocephalosporanic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP56119432A
Other languages
English (en)
Other versions
JPS638117B2 (ja
Inventor
Eemu Rune
Riyutsutsu Andore
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Roussel Uclaf SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf SA filed Critical Roussel Uclaf SA
Publication of JPS5762288A publication Critical patent/JPS5762288A/ja
Publication of JPS638117B2 publication Critical patent/JPS638117B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/26—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group
    • C07D501/34—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group with the 7-amino radical acylated by carboxylic acids containing hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38—Nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Paints Or Removers (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
JP56119432A 1976-01-23 1981-07-31 Novel oxime derivative of 7-aminothiazolylacetamidocephalosporanic acid, manufacture and pharmaceutical composition Granted JPS5762288A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7601834A FR2346014A1 (fr) 1976-01-23 1976-01-23 Nouvelles oximes derivees de l'acide 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments

Publications (2)

Publication Number Publication Date
JPS5762288A true JPS5762288A (en) 1982-04-15
JPS638117B2 JPS638117B2 (ja) 1988-02-19

Family

ID=9168296

Family Applications (7)

Application Number Title Priority Date Filing Date
JP3097080A Granted JPS55147290A (en) 1976-01-23 1980-03-13 Novel oxime derivative of 77aminothiazolylacetamidocephalosporanic acid* its manufacture and pharmaceutic composition
JP56119432A Granted JPS5762288A (en) 1976-01-23 1981-07-31 Novel oxime derivative of 7-aminothiazolylacetamidocephalosporanic acid, manufacture and pharmaceutical composition
JP59202156A Pending JPS60105670A (ja) 1976-01-23 1984-09-28 アミノチアゾリル酢酸の新規なオキシム誘導体
JP61154285A Granted JPS6226222A (ja) 1976-01-23 1986-07-02 細菌性感染症治療剤
JP61154284A Granted JPS6230787A (ja) 1976-01-23 1986-07-02 ７−アミノチアゾリルアセトアミドセフアロスポラン酸の新規なオキシム誘導体
JP62005195A Pending JPS62181248A (ja) 1976-01-23 1987-01-14 ２−（２−アミノチアゾリル）−２−ヒドロキシイミノ酢酸誘導体及びその製造法
JP62130077A Granted JPS6339869A (ja) 1976-01-23 1987-05-28 アミノチアゾリル酢酸の新規なオキシム誘導体及びその製造法

Family Applications Before (1)

Application Number Title Priority Date Filing Date
JP3097080A Granted JPS55147290A (en) 1976-01-23 1980-03-13 Novel oxime derivative of 77aminothiazolylacetamidocephalosporanic acid* its manufacture and pharmaceutic composition

Family Applications After (5)

Application Number Title Priority Date Filing Date
JP59202156A Pending JPS60105670A (ja) 1976-01-23 1984-09-28 アミノチアゾリル酢酸の新規なオキシム誘導体
JP61154285A Granted JPS6226222A (ja) 1976-01-23 1986-07-02 細菌性感染症治療剤
JP61154284A Granted JPS6230787A (ja) 1976-01-23 1986-07-02 ７−アミノチアゾリルアセトアミドセフアロスポラン酸の新規なオキシム誘導体
JP62005195A Pending JPS62181248A (ja) 1976-01-23 1987-01-14 ２−（２−アミノチアゾリル）−２−ヒドロキシイミノ酢酸誘導体及びその製造法
JP62130077A Granted JPS6339869A (ja) 1976-01-23 1987-05-28 アミノチアゾリル酢酸の新規なオキシム誘導体及びその製造法

Country Status (5)

Country Link
JP (7) JPS55147290A (ja)
FR (1) FR2346014A1 (ja)
GT (1) GT198172848A (ja)
PL (1) PL122968B1 (ja)
ZA (1) ZA77136B (ja)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5422392A (en) * 1977-07-19 1979-02-20 Roussel Uclaf Novel oxime derivative of 77aminothiazolylacetoamido cephalosporanic acid*their preparations and their applications as drugs
JPS61171464A (ja) * 1985-01-23 1986-08-02 Dai Ichi Seiyaku Co Ltd オキシイミノ酪酸誘導体の製法

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK162391C (da) * 1976-04-12 1992-03-09 Fujisawa Pharmaceutical Co Analogifremgangsmaade til fremstilling af syn-isomerer af 3,7-disubstituerede 3-cephem-4-carboxylsyreforbindelser
GR63088B (en) * 1976-04-14 1979-08-09 Takeda Chemical Industries Ltd Preparation process of novel cephalosporins
JPS6011713B2 (ja) * 1976-09-08 1985-03-27 武田薬品工業株式会社 セフアロスポリン誘導体およびその製造法
FR2399418A1 (fr) * 1977-03-14 1979-03-02 Fujisawa Pharmaceutical Co Procede de preparation d'acides iminoacetiques et nouveaux produits ainsi obtenus, utilises pour la synthese d'acides cepham- ou cephem-carboxyliques
DE2714880A1 (de) * 1977-04-02 1978-10-26 Hoechst Ag Cephemderivate und verfahren zu ihrer herstellung
FR2444032A2 (fr) * 1978-12-13 1980-07-11 Roussel Uclaf Nouveaux produits derives de l'acide 2-(2-tritylamino-4-thiazolyl) acetique et leur procede de preparation
FR2445830A1 (fr) * 1979-01-05 1980-08-01 Roussel Uclaf Nouveaux derives de l'acide (4-thiazolyl) acetique procede de preparation
FR2475545A1 (fr) * 1980-02-12 1981-08-14 Rhone Poulenc Ind Nouveaux thioloesters, leur preparation et leur utilisation en synthese
FR2475043A2 (fr) * 1980-02-06 1981-08-07 Roussel Uclaf Nouvelles oximes derivees de l'acide 2-(2-amino protege 4-thiazolyl) acetique, leur procede de preparation et leur application
FR2482594A2 (fr) * 1980-05-13 1981-11-20 Rhone Poulenc Ind Nouveaux thioloesters, leur preparation et leur utilisation en synthese
NL8100539A (nl) 1980-02-12 1981-09-01 Rhone Poulenc Ind Nieuwe thiolesters, de bereiding daarvan en hun gebruik bij syntheses.
IL63965A (en) * 1980-10-10 1985-01-31 Sparamedica Ag 7-(2-(2-amino-4-selenazoyl)acetamido)cephalosporin derivatives,and intermediates therefor,their preparation and pharmaceutical compositions containing them

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1536281A (en) * 1975-06-09 1978-12-20 Takeda Chemical Industries Ltd Cephem compounds

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5422392A (en) * 1977-07-19 1979-02-20 Roussel Uclaf Novel oxime derivative of 77aminothiazolylacetoamido cephalosporanic acid*their preparations and their applications as drugs
JPS6259708B2 (ja) * 1977-07-19 1987-12-12 Roussel Uclaf
JPS61171464A (ja) * 1985-01-23 1986-08-02 Dai Ichi Seiyaku Co Ltd オキシイミノ酪酸誘導体の製法

Also Published As

Publication number Publication date
FR2346014B1 (ja) 1979-10-05
GT198172848A (es) 1983-06-08
JPS60105670A (ja) 1985-06-11
JPS638117B2 (ja) 1988-02-19
JPS6230787A (ja) 1987-02-09
JPH0246596B2 (ja) 1990-10-16
PL122968B1 (en) 1982-09-30
JPS638107B2 (ja) 1988-02-19
JPS62181248A (ja) 1987-08-08
JPS55147290A (en) 1980-11-17
JPS6226222A (ja) 1987-02-04
FR2346014A1 (fr) 1977-10-28
JPH0246565B2 (ja) 1990-10-16
JPH0419229B2 (ja) 1992-03-30
ZA77136B (en) 1978-02-22
JPS6339869A (ja) 1988-02-20

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