ZA77136B - New oxime derivatives of 7-amino thiazolyl acetamido cephalosporanic acid,process for preparing them and pharmaceutical compositions - Google Patents

New oxime derivatives of 7-amino thiazolyl acetamido cephalosporanic acid,process for preparing them and pharmaceutical compositions

Info

Publication number
ZA77136B
ZA77136B ZA00770136A ZA77136A ZA77136B ZA 77136 B ZA77136 B ZA 77136B ZA 00770136 A ZA00770136 A ZA 00770136A ZA 77136 A ZA77136 A ZA 77136A ZA 77136 B ZA77136 B ZA 77136B
Authority
ZA
South Africa
Prior art keywords
preparing
pharmaceutical compositions
cephalosporanic acid
oxime derivatives
new oxime
Prior art date
Application number
ZA00770136A
Inventor
A Lutz
R Heymes
Original Assignee
Roussel Uclaf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf filed Critical Roussel Uclaf
Publication of ZA77136B publication Critical patent/ZA77136B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/26—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group
    • C07D501/34—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group with the 7-amino radical acylated by carboxylic acids containing hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38—Nitrogen atoms
ZA00770136A 1976-01-23 1977-01-11 New oxime derivatives of 7-amino thiazolyl acetamido cephalosporanic acid,process for preparing them and pharmaceutical compositions ZA77136B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7601834A FR2346014A1 (en) 1976-01-23 1976-01-23 Amino-thiazolyl-hydroxyimino-acetamido-cephalosporanic acids - with antibacterial activity

Publications (1)

Publication Number Publication Date
ZA77136B true ZA77136B (en) 1978-02-22

Family

ID=9168296

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA00770136A ZA77136B (en) 1976-01-23 1977-01-11 New oxime derivatives of 7-amino thiazolyl acetamido cephalosporanic acid,process for preparing them and pharmaceutical compositions

Country Status (5)

Country Link
JP (7) JPS55147290A (en)
FR (1) FR2346014A1 (en)
GT (1) GT198172848A (en)
PL (1) PL122968B1 (en)
ZA (1) ZA77136B (en)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2408613A2 (en) * 1977-07-19 1979-06-08 Roussel Uclaf NEW OXIMES DERIVED FROM 7-AMINO THIAZOLYL ACETAMIDO CEPHALOSPORANIC ACID, THEIR PREPARATION PROCESS AND THEIR APPLICATION AS MEDICINAL PRODUCTS
DK162391C (en) * 1976-04-12 1992-03-09 Fujisawa Pharmaceutical Co ANALOGY PROCEDURE FOR PREPARING SYN-ISOMERS OF 3,7-DISUBSTITUTED 3-CEPHEM-4-CARBOXYLIC ACID COMPOUNDS
DE2715385A1 (en) * 1976-04-14 1977-11-10 Takeda Chemical Industries Ltd CEPHALOSPORIN DERIVATIVES, THE PROCESS FOR THEIR MANUFACTURING AND MEDICINAL PRODUCTS CONTAINING THEM
JPS6011713B2 (en) * 1976-09-08 1985-03-27 武田薬品工業株式会社 Cephalosporin derivatives and their production method
FR2399418A1 (en) * 1977-03-14 1979-03-02 Fujisawa Pharmaceutical Co Heterocyclyl-imino-acetamido-cephalosporin derivs.
DE2714880A1 (en) * 1977-04-02 1978-10-26 Hoechst Ag CEPHEMDER DERIVATIVES AND PROCESS FOR THEIR PRODUCTION
FR2444032A2 (en) * 1978-12-13 1980-07-11 Roussel Uclaf 2-Thiazolyl-2-vinyloxy-imino-acetamido-cephalosporin derivs. - useful as antibacterials effective against Gram positive and negative bacteria
FR2445830A1 (en) * 1979-01-05 1980-08-01 Roussel Uclaf 7-Amino-thiazolyl-acetamido-cephalosporin oxime derivs. - are broad spectrum antibacterials useful against penicillin resistant Staphylococci (BE 25.9.78)
FR2475545A1 (en) * 1980-02-12 1981-08-14 Rhone Poulenc Ind 7-Amino-thiazolyl methoxy-imino acetamido 3-thio-vinyl-cephalosporin - antibacterials active against Gram negative and Gram positive bacteria
FR2475043A2 (en) * 1980-02-06 1981-08-07 Roussel Uclaf Amino:thiazolyl hydroxy:imino acetic ester(s) - protected on the amino gp. are intermediates for cephalosporanic acid antibiotics
NL8100539A (en) 1980-02-12 1981-09-01 Rhone Poulenc Ind NEW THIOLESTERS, THEIR PREPARATION AND THEIR USE IN SYNTHESIS.
FR2482594A2 (en) * 1980-05-13 1981-11-20 Rhone Poulenc Ind 2-Amino-thiazol-4-yl alpha-oximino-acetyl:thioalkyl cpds. - useful as side chains for broad spectrum antibacterials
IL63965A (en) * 1980-10-10 1985-01-31 Sparamedica Ag 7-(2-(2-amino-4-selenazoyl)acetamido)cephalosporin derivatives,and intermediates therefor,their preparation and pharmaceutical compositions containing them
JPS61171464A (en) * 1985-01-23 1986-08-02 Dai Ichi Seiyaku Co Ltd Production of oxyiminobutyric acid derivative

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1536281A (en) * 1975-06-09 1978-12-20 Takeda Chemical Industries Ltd Cephem compounds

Also Published As

Publication number Publication date
JPS6230787A (en) 1987-02-09
JPS55147290A (en) 1980-11-17
JPS638107B2 (en) 1988-02-19
FR2346014B1 (en) 1979-10-05
JPH0419229B2 (en) 1992-03-30
PL122968B1 (en) 1982-09-30
JPS60105670A (en) 1985-06-11
JPS6339869A (en) 1988-02-20
JPS5762288A (en) 1982-04-15
JPS62181248A (en) 1987-08-08
JPS638117B2 (en) 1988-02-19
JPH0246565B2 (en) 1990-10-16
JPS6226222A (en) 1987-02-04
FR2346014A1 (en) 1977-10-28
JPH0246596B2 (en) 1990-10-16
GT198172848A (en) 1983-06-08

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