FR2408613A2 - NEW OXIMES DERIVED FROM 7-AMINO THIAZOLYL ACETAMIDO CEPHALOSPORANIC ACID, THEIR PREPARATION PROCESS AND THEIR APPLICATION AS MEDICINAL PRODUCTS - Google Patents

NEW OXIMES DERIVED FROM 7-AMINO THIAZOLYL ACETAMIDO CEPHALOSPORANIC ACID, THEIR PREPARATION PROCESS AND THEIR APPLICATION AS MEDICINAL PRODUCTS

Info

Publication number
FR2408613A2
FR2408613A2 FR7722077A FR7722077A FR2408613A2 FR 2408613 A2 FR2408613 A2 FR 2408613A2 FR 7722077 A FR7722077 A FR 7722077A FR 7722077 A FR7722077 A FR 7722077A FR 2408613 A2 FR2408613 A2 FR 2408613A2
Authority
FR
France
Prior art keywords
carboxylic
acid
thiazolyl
amino
application
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7722077A
Other languages
French (fr)
Other versions
FR2408613B2 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Roussel Uclaf SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf SA filed Critical Roussel Uclaf SA
Priority to FR7722077A priority Critical patent/FR2408613A2/en
Priority to SE787807274A priority patent/SE7807274L/en
Priority to US05/920,704 priority patent/US4196205A/en
Priority to ES471647A priority patent/ES471647A2/en
Priority to JP8410078A priority patent/JPS5422392A/en
Priority to DE19782831332 priority patent/DE2831332A1/en
Priority to BE189345A priority patent/BE869079R/en
Priority to IT50356/78A priority patent/IT1156871B/en
Priority to AU38133/78A priority patent/AU527621B2/en
Priority to LU79998A priority patent/LU79998A1/en
Priority to CH773178A priority patent/CH632503A5/en
Priority to DK320578A priority patent/DK162094C/en
Priority to NL7807741A priority patent/NL7807741A/en
Priority to IE1450/78A priority patent/IE47335B1/en
Priority to CA307,727A priority patent/CA1123824A/en
Priority to GB8029620A priority patent/GB2056988B/en
Priority to AT522878A priority patent/AT359644B/en
Priority to GB7830305A priority patent/GB2005660B/en
Priority to ES479027A priority patent/ES479027A1/en
Publication of FR2408613A2 publication Critical patent/FR2408613A2/en
Application granted granted Critical
Publication of FR2408613B2 publication Critical patent/FR2408613B2/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/587—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with aliphatic hydrocarbon radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms, said aliphatic radicals being substituted in the alpha-position to the ring by a hetero atom, e.g. with m >= 0, Z being a singly or a doubly bound hetero atom

Abstract

PRODUITS SUIVANTS REPONDANT A LA FORMULEI DU BREVET PRINCIPAL: -L'ACIDE 3-ACETOXYMEHTUL 7-2 (2 TRITYLAMINO 4-THIAZOLYL) 2 VINYLOXYIMINO ACETAMIDO CEPH 3 4-CARBOXYLIQUE ISOMERE SYN, -LE SEL DE SODIUM DE L'ACIDE 3-ACETOXYMETHYL 72 (2 TRITYLAMINO 4-THIAZOLYL) 2 VINYLOXYYIMINO ACETAMIDOCEPH 3 4-CARBOXYLIQUE ISOMERE SYN, L'ACIDE 3-ACETOXYMETHYL 7-2 (2 AMINO 4-THIAZOLYL) 2 VINYLOXYIMINO ACETAMIDOCEPH 3 4-CARBOXYLIQUE ISOMERE SYN ET SES SELS AVEC LES METAUX ALCALINS, ALCALINO-TERREUX, LE MAGNESIUM OU LES BASES ORGANIQUES ANIMEES. PROCEDE DE PREPARATION ET APPLICATION A TITRE DE MEDICAMENTS DE CES PRODUITS.FOLLOWING PRODUCTS RESPONDING TO THE FORMULA I OF THE MAIN PATENT: -3-ACETOXYMEHTUL 7-2 ACID (2 TRITYLAMINO 4-THIAZOLYL) 2 VINYLOXYIMINO ACETAMIDO CEPH 3 4-CARBOXYLIC ACID ISOMER SYN, -ETYLACID 3-ACETOXYMEHTUL -3 -ETYLACID -ETHACID 3 -ETHYL ACID -ETHYLACID 3 -ETHIAZOLYL 72 (2 TRITYLAMINO 4-THIAZOLYL) 2 VINYLOXYYIMINO ACETAMIDOCEPH 3 4-CARBOXYLIC ISOMER SYN, 3-ACETOXYMETHYL ACID 7-2 (2 AMINO 4-THIAZOLYL) 2 VINYLOXYIMINO ACETAMIDOCEPH 3 4-CARBOXYLIC ISOMER SYN, 3-ACETOXYMETHYL ACID 7-2 (2 AMINO 4-THIAZOLYL) 2 VINYLOXYIMINO AND 3-CARBOXYLIC ISOMID-CARBOXYLIC 3-ACETOXYMETHYL ACID WITH 3-ACETOXYMETHYL ACID 7-2 (2 AMINO 4-THIAZOLYL) 2 VINYLOXYIMINO AND 3-CARBOXYLIC ACETAMIDOCEPH 3-ALINSAL-CARBOXYIMINO AND 3-CARBOXYLIC ISOMID-CARBOCE , ALKALINO-EARTH, MAGNESIUM OR ANIMATED ORGANIC BASES. PROCESS FOR PREPARATION AND APPLICATION AS MEDICINAL PRODUCTS OF THESE PRODUCTS.

FR7722077A 1976-01-23 1977-07-19 NEW OXIMES DERIVED FROM 7-AMINO THIAZOLYL ACETAMIDO CEPHALOSPORANIC ACID, THEIR PREPARATION PROCESS AND THEIR APPLICATION AS MEDICINAL PRODUCTS Granted FR2408613A2 (en)

Priority Applications (19)

Application Number Priority Date Filing Date Title
FR7722077A FR2408613A2 (en) 1977-07-19 1977-07-19 NEW OXIMES DERIVED FROM 7-AMINO THIAZOLYL ACETAMIDO CEPHALOSPORANIC ACID, THEIR PREPARATION PROCESS AND THEIR APPLICATION AS MEDICINAL PRODUCTS
SE787807274A SE7807274L (en) 1977-07-19 1978-06-27 NEW OXIMERIVATIVES OF 7-AMINO-THIAZOLYL-ACETAMIDO-CEPHALOSPORANIC ACID AND METHODS OF PREPARATION THEREOF
US05/920,704 US4196205A (en) 1976-01-23 1978-06-30 3-Acetoxymethyl-7-(iminoacetamido)-cephalosporanic acid derivatives
ES471647A ES471647A2 (en) 1977-07-19 1978-07-12 Oxime derivatives of 7-amino- thiazolyl-acetamido-cephalo- sporanic acid
JP8410078A JPS5422392A (en) 1977-07-19 1978-07-12 Novel oxime derivative of 77aminothiazolylacetoamido cephalosporanic acid*their preparations and their applications as drugs
DE19782831332 DE2831332A1 (en) 1977-07-19 1978-07-17 VINYLOXYIMINO DERIVATIVES OF 7-AMINOTHIAZOLYL ACETAMIDOCEPHALOSPORIC ACID, THEIR PRODUCTION AND PHARMACEUTICAL COMPOSITIONS
CH773178A CH632503A5 (en) 1977-07-19 1978-07-18 OXIMES OF 2- (4-THIAZOLYL) -ACETIC ACID.
IT50356/78A IT1156871B (en) 1977-07-19 1978-07-18 PROCEDURE FOR THE PRODUCTION OF OXIMATE DERIVATIVES OF 7-AMINOTHIAZOLYL ACETAMIDE-CEPHALORANIC ACID
AU38133/78A AU527621B2 (en) 1977-07-19 1978-07-18 Derivatives of 2-imino 2-(2-tritylamino 4-thiazolyl) acetic acid
LU79998A LU79998A1 (en) 1977-07-19 1978-07-18 PROCESS FOR THE PREPARATION OF NEW OXIMES DERIVED FROM 7-AMINO THIAZOLYL ACETAMIDE CEPHALOSPORANIC
BE189345A BE869079R (en) 1977-07-19 1978-07-18 NEW OXIMES DERIVED FROM 7-AMINO THIAZOLYL ACETAMIDO CEPHALOSPORANIC ACID, METHOD OF PREPARATION AND PHARMACEUTICAL COMPOSITIONS
DK320578A DK162094C (en) 1977-07-19 1978-07-18 2- (2-TRITYLAMINO-4-THIAZOLYL) -2-VINYLOXYIMINOIC ACETIC ACID, SYN-ISOMER, USING AS AN INTERMEDIATE IN THE PREPARATION OF SYN-ISOMER OXIMELE MOSPHEREO-MOSHYL
IE1450/78A IE47335B1 (en) 1977-07-19 1978-07-19 Oxime derivatives of 7-amino-thiazolyl-acetamidocephalosporanic
CA307,727A CA1123824A (en) 1977-07-19 1978-07-19 Oximes derivatives of the 7-amino-thiazolyl-acetamido- cephalosporanic acid, preparation process and use as a drug
GB8029620A GB2056988B (en) 1977-07-19 1978-07-19 Oxime derivatives of 2 - (2 - tritylamino-thiazolyl) - acetic acid and alkyl esters thereof
AT522878A AT359644B (en) 1977-07-19 1978-07-19 METHOD FOR PRODUCING NEW OXIMES OF 7-AMINOTHIAZOLYLACETAMIDOCEPHALOSPORANIC ACID AND THEIR SALTS
GB7830305A GB2005660B (en) 1977-07-19 1978-07-19 Oxime derivatives of 7-amino-thiazolyl-acetamido-cephalosporanic acid
NL7807741A NL7807741A (en) 1977-07-19 1978-07-19 NEW OXIME COMPOUNDS OF 7-AMINO-THIAZOLYL-ACEETA-MIDOCEPHALOSPORANIC ACID, METHOD FOR THEIR PREPARATION AND THEIR USE AS MEDICINAL PRODUCTS.
ES479027A ES479027A1 (en) 1977-07-19 1979-03-28 Oxime derivatives of 7-amino- thiazolyl-acetamido-cephalo- sporanic acid

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7722077A FR2408613A2 (en) 1977-07-19 1977-07-19 NEW OXIMES DERIVED FROM 7-AMINO THIAZOLYL ACETAMIDO CEPHALOSPORANIC ACID, THEIR PREPARATION PROCESS AND THEIR APPLICATION AS MEDICINAL PRODUCTS

Publications (2)

Publication Number Publication Date
FR2408613A2 true FR2408613A2 (en) 1979-06-08
FR2408613B2 FR2408613B2 (en) 1980-04-18

Family

ID=9193491

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7722077A Granted FR2408613A2 (en) 1976-01-23 1977-07-19 NEW OXIMES DERIVED FROM 7-AMINO THIAZOLYL ACETAMIDO CEPHALOSPORANIC ACID, THEIR PREPARATION PROCESS AND THEIR APPLICATION AS MEDICINAL PRODUCTS

Country Status (16)

Country Link
JP (1) JPS5422392A (en)
AT (1) AT359644B (en)
AU (1) AU527621B2 (en)
BE (1) BE869079R (en)
CA (1) CA1123824A (en)
CH (1) CH632503A5 (en)
DE (1) DE2831332A1 (en)
DK (1) DK162094C (en)
ES (2) ES471647A2 (en)
FR (1) FR2408613A2 (en)
GB (2) GB2056988B (en)
IE (1) IE47335B1 (en)
IT (1) IT1156871B (en)
LU (1) LU79998A1 (en)
NL (1) NL7807741A (en)
SE (1) SE7807274L (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2399418A1 (en) * 1977-03-14 1979-03-02 Fujisawa Pharmaceutical Co Heterocyclyl-imino-acetamido-cephalosporin derivs.

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PH17188A (en) * 1977-03-14 1984-06-14 Fujisawa Pharmaceutical Co New cephem and cepham compounds and their pharmaceutical compositions and method of use
FR2476647A2 (en) * 1980-02-26 1981-08-28 Roussel Uclaf 7-Amino-thiazolyl-acetamido-cephalosporin oxime derivs. - are broad spectrum antibacterials useful against penicillin resistant Staphylococci (BE 25.9.78)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE440655B (en) * 1976-01-23 1985-08-12 Roussel Uclaf SET TO MAKE NEW OXIME DERIVATIVES OF 7-AMINO-THIAZOLYL-ACETAMIDO-CEPHALOSPORANIC ACID
FR2346014A1 (en) * 1976-01-23 1977-10-28 Roussel Uclaf Amino-thiazolyl-hydroxyimino-acetamido-cephalosporanic acids - with antibacterial activity

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2399418A1 (en) * 1977-03-14 1979-03-02 Fujisawa Pharmaceutical Co Heterocyclyl-imino-acetamido-cephalosporin derivs.

Also Published As

Publication number Publication date
GB2056988B (en) 1982-11-17
IE781450L (en) 1979-01-19
SE7807274L (en) 1979-01-20
IT1156871B (en) 1987-02-04
GB2005660A (en) 1979-04-25
DE2831332A1 (en) 1979-02-08
DK320578A (en) 1979-01-20
GB2005660B (en) 1982-03-10
ATA522878A (en) 1980-04-15
JPS5422392A (en) 1979-02-20
AU3813378A (en) 1980-01-24
DK162094B (en) 1991-09-16
DK162094C (en) 1992-02-17
BE869079R (en) 1979-01-18
IE47335B1 (en) 1984-02-22
JPS6259708B2 (en) 1987-12-12
LU79998A1 (en) 1979-04-09
GB2056988A (en) 1981-03-25
AT359644B (en) 1980-11-25
CA1123824A (en) 1982-05-18
NL7807741A (en) 1979-01-23
AU527621B2 (en) 1983-03-17
ES471647A2 (en) 1979-10-16
CH632503A5 (en) 1982-10-15
IT7850356A0 (en) 1978-07-18
ES479027A1 (en) 1979-07-01
FR2408613B2 (en) 1980-04-18

Similar Documents

Publication Publication Date Title
US4562073A (en) Penicillin derivatives
DE2810922A1 (en) NEW CEPHEM AND CEPHAM COMPOUNDS, METHODS OF MANUFACTURING THEM AND MEDICINAL PRODUCTS CONTAINING THEM
FR2432521A1 (en) NOVEL O-SUBSTITUTED OXIMES DERIVED FROM 7-AMINO THIAZOLYL ACETAMIDO CEPHALOSPORANIC ACID, THEIR PREPARATION PROCESS AND THEIR USE AS MEDICAMENTS
AU520657B2 (en) Oxime Derivatives of 3- acetoxy methyl 7-amino thiazolyl acetamido cephalosporanic acid, process for preparing them and pharmaceutical compositions
ES455089A1 (en) Oxime derivatives of 7-aminothiazolylacetamido-cephalosporanic acid processes for preparing them and pharmaceutical compositions incorporating them
JPS63146863A (en) Carboxylic acids
IE780899L (en) Azetidinopyrrole derivatives
FR2400519A1 (en) CRYSTALLINE FORM OF SODIUM SALT OF AN OXIMIN DERIVATIVE OF 7-AMINO-THIAZOLYL ACETAMIDO CEPHALOSPORANIC, ITS PREPARATION PROCESS AND ITS APPLICATION AS A MEDICINAL PRODUCT
FR2410655A1 (en) NEW OXIMES DERIVED FROM 3-SUBSTITUTE 7-AMINO THIAZOLYL ACETAMIDO CEPHALOSPORANIC, THEIR METHOD OF PREPARATION AND THEIR APPLICATION AS MEDICINAL PRODUCTS
FR2384779A1 (en) NEW OXIMES DERIVED FROM 3-CHLORO OR 3-METHOXY 7-AMINO THIAZOLYL ACETAMIDO CEPHALOSPORANIC, THEIR PREPARATION PROCESS AND THEIR APPLICATION AS MEDICINAL PRODUCTS
FR2501209B1 (en) NOVEL CEPHALOSPORIN DERIVATIVES AND ANTIBIOTIC DRUGS CONTAINING THE SAME
ATE2621T1 (en) NEW LACTAME, PROCESS FOR THEIR PREPARATION AND MEDICATIONS CONTAINING THESE COMPOUNDS.
FR2408613A2 (en) NEW OXIMES DERIVED FROM 7-AMINO THIAZOLYL ACETAMIDO CEPHALOSPORANIC ACID, THEIR PREPARATION PROCESS AND THEIR APPLICATION AS MEDICINAL PRODUCTS
ES8307820A1 (en) Cephalosporin esters, process for their preparation and pharmaceutical compositions containing them.
FR2421907A1 (en) NEW CEPHALOSPORINS DERIVED FROM 7- / 2- (2-AMINO 4-THIAZOLYL) 2- (CARBOXYMETHOXYIMINO / ACETAMIDO 3-SUBSTITUTE CEPHALOSPORANIC ACID, THEIR METHOD OF PREPARATION AND THEIR APPLICATION AS MEDICINAL PRODUCTS
FR2361895A1 (en) NEW OXIMES DERIVED FROM 3-CARBAMOYLOXYMETHYL 7-AMINO THIAZOLYL ACETAMIDO CEPHALOSPORANIC, THEIR PREPARATION PROCESS AND THEIR APPLICATION AS MEDICINAL PRODUCTS
BE865298A (en) NEW OXIMES DERIVED FROM 3-ACETOXY-METHYL 7-AMINO THIAZOLYL ACETAMIDO CEPHALOSPORANIC, METHOD OF PREPARATION AND PHARMACEUTICAL COMPOSITIONS
FR2381053A1 (en) NEW OXIMES DERIVED FROM 3-THIADIAZOLYL THIOMETHYL 7-AMINOTHIAZOLYL ACETAMIDO CEPHALOSPORANIC, THEIR PREPARATION PROCESS AND THEIR APPLICATION AS MEDICINAL PRODUCTS
IS4064A (en) Derivatives of polyhydroxy five-ring rings, their preparation and use as pharmaceuticals
GB1382494A (en) Acylaminocephalosporanic acids and process for their manufacture
OA06223A (en) Process for the preparation of novel oximes derived from 3-azidomethyl 7-amino thiazolyl acetamido cephalosporanic acid.
FR2433945A1 (en) PHARMACEUTICAL COMPOSITION FOR RECTAL ADMINISTRATION OF CEPHALOSPORIN
KR0135979B1 (en) Method for recovery of anti-biotics from mother liquors
KR890014560A (en) Cephalosporin derivatives and preparation methods thereof
GB1261780A (en) Orally active sulfur-containing cephalosporin antibiotics