JPS5735910B2 - - Google Patents

Info

Publication number
JPS5735910B2
JPS5735910B2 JP2351579A JP2351579A JPS5735910B2 JP S5735910 B2 JPS5735910 B2 JP S5735910B2 JP 2351579 A JP2351579 A JP 2351579A JP 2351579 A JP2351579 A JP 2351579A JP S5735910 B2 JPS5735910 B2 JP S5735910B2
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
JP2351579A
Other versions
JPS54122250A (en
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of JPS54122250A publication Critical patent/JPS54122250A/ja
Publication of JPS5735910B2 publication Critical patent/JPS5735910B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44—Iso-indoles; Hydrogenated iso-indoles
    • C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
JP2351579A 1978-03-04 1979-03-02 Phenoxyalkylcarboxylic acid derivative*its manufacture and medicine containing said derivative and having blood platelet agglutination preventing activity and*or lipid reducing activity Granted JPS54122250A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19782809377 DE2809377A1 (de) 1978-03-04 1978-03-04 Phenoxyalkylcarbonsaeure-derivate, verfahren zu deren herstellung sowie diese verbindungen enthaltende arzneimittel

Publications (2)

Publication Number Publication Date
JPS54122250A JPS54122250A (en) 1979-09-21
JPS5735910B2 true JPS5735910B2 (ja) 1982-07-31

Family

ID=6033559

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2351579A Granted JPS54122250A (en) 1978-03-04 1979-03-02 Phenoxyalkylcarboxylic acid derivative*its manufacture and medicine containing said derivative and having blood platelet agglutination preventing activity and*or lipid reducing activity

Country Status (20)

Country Link
US (1) US4258058A (ja)
EP (1) EP0004011B1 (ja)
JP (1) JPS54122250A (ja)
AT (1) AT367745B (ja)
AU (1) AU508419B2 (ja)
CA (1) CA1136158A (ja)
CS (3) CS208775B2 (ja)
DD (1) DD142334A5 (ja)
DE (2) DE2809377A1 (ja)
DK (1) DK164545C (ja)
ES (1) ES478228A1 (ja)
FI (1) FI71305C (ja)
HU (1) HU183085B (ja)
IL (1) IL56734A0 (ja)
NZ (1) NZ189776A (ja)
PL (2) PL124924B1 (ja)
PT (1) PT69295A (ja)
SU (2) SU1052157A3 (ja)
YU (2) YU42300B (ja)
ZA (1) ZA79989B (ja)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH041533Y2 (ja) * 1985-01-19 1992-01-20

Families Citing this family (54)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3000377A1 (de) * 1980-01-07 1981-07-09 Boehringer Mannheim Gmbh, 6800 Mannheim Neue sulfonamide, verfahren zu deren herstellung sowie diese verbindungen enthaltende arzneimittel
DE3535167A1 (de) * 1985-10-02 1987-04-09 Boehringer Mannheim Gmbh Neue sulfonyl-phenyl(alkyl)amine, verfahren zu ihrer herstellung sowie arzneimittel
GB8528398D0 (en) * 1985-11-19 1985-12-24 Glaxo Group Ltd Chemical compounds
DE3610643A1 (de) * 1986-03-29 1987-10-01 Boehringer Mannheim Gmbh Neue phenoxyalkylcarbonsaeure-derivate, verfahren zu ihrer herstellung sowie diese verbindungen enthaltende arzneimittel
DE3623941A1 (de) * 1986-07-16 1988-01-28 Bayer Ag Substituierte amino-5,6,7,8-tetrahydronaphthyl-oxyessigsaeuren, verfahren zu deren herstellung sowie die verwendung als arzneimittel
IL83230A (en) * 1986-08-06 1992-06-21 Tanabe Seiyaku Co Phenoxyacetic acid derivatives,their preparation and pharmaceutical compositions containing them
DE3642105A1 (de) * 1986-12-10 1988-06-16 Bayer Ag Substituierte aminomethyl-5,6,7,8-tetrahydronaphtyl-oxyessigsaeuren, neue zwischenprodukte, verfahren zu ihrer herstellung sowie ihre verwendung in arzneimitteln
GB8708233D0 (en) * 1987-04-07 1987-05-13 Smith Kline French Lab Pharmaceutically active compounds
US4752616A (en) * 1987-06-29 1988-06-21 E. R. Squibb & Sons, Inc. Arylthioalkylphenyl carboxylic acids, compositions containing same and method of use
US4752613A (en) * 1987-08-03 1988-06-21 E. R. Squibb & Sons, Inc. Sulphonamidothienylcarboxylic acid compounds
US4783473A (en) * 1987-09-02 1988-11-08 E. R. Squibb & Sons, Inc. Geminally substituted cyclic ether carboxylic acids, derivatives thereof, compositions containing same and method of use
US4931460A (en) * 1987-09-17 1990-06-05 E. R. Squibb & Sons, Inc. Post-ischemic myocardial dysfunction using thromboxane A2 antagonists
JPH068274B2 (ja) * 1988-01-19 1994-02-02 田辺製薬株式会社 フェノキシ酢酸誘導体
EP0325245B1 (en) * 1988-01-19 1993-10-20 Tanabe Seiyaku Co., Ltd. Phenoxyacetic acid derivatives, preparation thereof, pharmaceutical compositions comprising them and use
JPH068275B2 (ja) * 1988-02-04 1994-02-02 田辺製薬株式会社 フェノキシ酢酸誘導体
JPH01279826A (ja) * 1988-01-29 1989-11-10 Tanabe Seiyaku Co Ltd 血小板凝集抑制剤
US5066480A (en) * 1988-04-11 1991-11-19 E. R. Squibb & Sons, Inc. Method of preventing or reducing adverse reactions to protamine using a thromboxane a2 receptor antagonist
US4900723A (en) * 1988-04-29 1990-02-13 E. R. Squibb & Sons, Inc. Method of preventing or reducing venous thrombosis using a thromboxane A2 receptor antagonist in conjunction with heparin and combination
DE3819052A1 (de) * 1988-06-04 1989-12-07 Basf Ag Neue sulfonamid-derivate, ihre herstellung und verwendung
US4925873A (en) * 1988-09-01 1990-05-15 E. R. Squibb & Sons, Inc. Method of treating skin injuries using thromboxane A2 receptor antagonists
US5280043A (en) * 1988-10-10 1994-01-18 Smith Kline & French Laboratories Ltd. Sulphonamido containing phenylalkanoic acids as thromboxane A2 antagonists
US4959383A (en) * 1988-10-31 1990-09-25 E. R. Squibb & Sons, Inc. Phenylsulfone alkenoic acids, derivatives thereof, compositions containing same and method of use
US5006542A (en) * 1988-10-31 1991-04-09 E. R. Squibb & Sons, Inc. Arylthioalkylphenyl carboxylic acids, derivatives thereof, compositions containing same and method of use
US5070099A (en) * 1988-10-31 1991-12-03 E. R. Squibb & Sons, Inc. Arylthioalkylphenyl carboxylic acids, derivatives thereof, compositions containing same method of use
US4975452A (en) * 1989-06-02 1990-12-04 E. R. Squibb & Sons, Inc. Geminally substituted thiaheterocyclic carboxylic acids and derivatives thereof
US5106991A (en) * 1989-06-02 1992-04-21 E. R. Squibb & Sons, Inc. Geminally substituted thiaheterocyclic carboxylic acids and derivatives thereof
US5153214A (en) * 1989-06-28 1992-10-06 Ciba-Geigy Corporation Certain (arylsulfonamido- and imidazolyl-)-substituted carboxylic acids and derivatives thereof and use for suppressing thromboxane activity
US5025025A (en) * 1989-06-28 1991-06-18 Ciba-Geigy Corporation (Arylsulfonamido- and pyridyl-)-substituted carboxylic acids and derivatives thereof and use for suppressing thromboxane activity
US5264458A (en) * 1989-11-02 1993-11-23 Bayer Aktiengesellschaft Antithrombotic iso- and heterocyclic phenylsulphonamides
DE3942923A1 (de) * 1989-12-23 1991-06-27 Boehringer Mannheim Gmbh Neue phenoxyalkylcarbonsaeure-amide, verfahren zu ihrer herstellung sowie diese verbindungen enthaltende arzneimittel
DE4006640A1 (de) * 1990-03-03 1991-09-05 Boehringer Mannheim Gmbh Phenylthioalkylcarbonsaeure-derivate, verfahren zu ihrer herstellung sowie diese verbindungen enthaltende arzneimittel
DE4010536A1 (de) * 1990-04-02 1991-10-10 Boehringer Mannheim Gmbh Pharmazeutische waessrige loesung von 4-(2-(benzolsulfonylamino)-ethyl)-phenoxyessigsaeure
US5189211A (en) * 1990-08-01 1993-02-23 Taisho Pharmaceutical Co., Ltd. Sulfonamide derivatives
NZ239846A (en) * 1990-09-27 1994-11-25 Merck & Co Inc Sulphonamide derivatives and pharmaceutical compositions thereof
DE4037174A1 (de) * 1990-11-22 1992-05-27 Boehringer Mannheim Gmbh Neue sulfonamide, verfahren zu ihrer herstellung und arzneimittel, die diese verbindungen enthalten
DE4041780A1 (de) * 1990-12-24 1992-06-25 Boehringer Mannheim Gmbh Neue amine, verfahren zu ihrer herstellung, sowie diese verbindungen enthaltende arzneimittel
JPH05125038A (ja) * 1991-03-07 1993-05-21 Tanabe Seiyaku Co Ltd フエノキシアルカン酸誘導体及びその製法
US5280034A (en) * 1991-08-23 1994-01-18 E. R. Squibb & Sons, Inc. Bis-heterocyclic prostaglandin analogs
US5827868A (en) * 1991-10-07 1998-10-27 E. R. Squibb & Sons, Inc. Prostaglandin analogs
TW219358B (ja) * 1991-12-20 1994-01-21 Hokuriku Pharmaceutical
US5206373A (en) * 1992-02-28 1993-04-27 Merck & Co., Inc. Process for preparing fibrinogen receptor antagonists
GB9220137D0 (en) * 1992-09-23 1992-11-04 Pfizer Ltd Therapeutic agents
JPH0753505A (ja) * 1992-10-01 1995-02-28 Hokuriku Seiyaku Co Ltd ベンゼンスルホンアミド誘導体及びその用途
GB9702194D0 (en) * 1997-02-04 1997-03-26 Lilly Co Eli Sulphonide derivatives
US6822001B2 (en) 2000-11-03 2004-11-23 Tularik Inc. Combination therapy using pentafluorobenzenesulfonamides and antineoplastic agents
CA2439255C (en) * 2001-02-28 2011-01-04 Temple University Of The Commonwealth System Of Higher Education N-(aryl)-2-arylethenesulfonamides and therapeutic uses thereof
JP4538233B2 (ja) * 2002-02-28 2010-09-08 テンプル・ユニバーシティ−オブ・ザ・コモンウェルス・システム・オブ・ハイアー・エデュケイション 増殖性障害治療用の、アミノ置換されたスルホンアニリド及びその誘導体
ATE525067T1 (de) * 2002-02-28 2011-10-15 Univ Temple Amino-substituierte (e)-2,6-dialkoxystyryl 4- substituierte benzylsulfone zur behandlung von proliferierenden erkrankungen
FR2841550B1 (fr) * 2002-06-26 2007-05-04 Sederma Sa Nouvelles molecules derivees de la tyramine, leur mode de preparation, et leur utilisation seules ou associees dans des compositions cosmetiques ou dermopharmceutiques
US20060155269A1 (en) * 2005-01-12 2006-07-13 Prorhythm, Inc. Epicardial ablation using focused ultrasound
JP2007106697A (ja) * 2005-10-13 2007-04-26 Sederma Sa 新規なチラミン誘導体及びその製造方法、並びに該誘導体を含む化粧用組成物、若しくは皮膚用医薬組成物
EP3142655B1 (en) 2014-05-16 2020-12-02 Cumberland Pharmaceuticals Inc. Compositions and methods of treating cardiac fibrosis with ifetroban
AU2016285566A1 (en) 2015-06-30 2017-12-14 Cumberland Pharmaceuticals, Inc. Thromboxane receptor antagonists in AERD/asthma
AU2017263462B2 (en) 2016-05-11 2021-05-13 Cumberland Pharmaceuticals, Inc. Compositions and methods of treating muscular dystrophy with thromboxane-A2 receptor antagonists

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3364249A (en) * 1964-01-30 1968-01-16 Merck & Co Inc N-carboxyalkyl-phenoxyalkanoic acid amide
US3402198A (en) * 1965-10-20 1968-09-17 William A. Bolhofer 2-(phenoxy), 2-(phenylthio) and 2-(anilino) substituted 2-alkylideneacetic acid derivatives
GB1121722A (en) * 1966-03-31 1968-07-31 Ici Ltd New carboxylic acid derivatives
US3549689A (en) * 1967-05-23 1970-12-22 Sandoz Ag Phenoxy-alkanoic acids
US3629320A (en) * 1969-04-09 1971-12-21 Geigy Chem Corp 2-(4-halo- and 4-trifluoromethylphenylsulfonamido)phenylacetic acids and esters thereof
US3720709A (en) * 1969-12-16 1973-03-13 Merck & Co Inc Sulfonylphenoxyalkanoic acids
DE2149070C3 (de) * 1971-10-01 1978-03-23 Boehringer Mannheim Gmbh, 6800 Mannheim Phenoxyalkylcarbonsäurederivate und deren Salze, Verfahren zu deren Herstellung und Arzneimittel
DE2405622A1 (de) * 1974-02-06 1975-08-14 Boehringer Mannheim Gmbh Neue phenoxyalkylcarbonsaeurederivate und verfahren zur herstellung derselben
DE2541342A1 (de) * 1975-09-17 1977-03-31 Boehringer Mannheim Gmbh Neue phenoxyalkylcarbonsaeuren und verfahren zur herstellung derselben
US4112236A (en) * 1977-04-04 1978-09-05 Merck & Co., Inc. Interphenylene 8-aza-9-dioxothia-11,12-secoprostaglandins

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH041533Y2 (ja) * 1985-01-19 1992-01-20

Also Published As

Publication number Publication date
DK164545B (da) 1992-07-13
FI71305C (fi) 1986-12-19
CS208776B2 (en) 1981-09-15
YU42916B (en) 1988-12-31
EP0004011A1 (de) 1979-09-19
DE2960222D1 (en) 1981-04-23
DK164545C (da) 1992-11-30
AU508419B2 (en) 1980-03-20
DK81579A (da) 1979-09-05
ATA161979A (de) 1981-12-15
YU48179A (en) 1983-02-28
PL123364B1 (en) 1982-10-30
YU98186A (en) 1986-10-31
CS208775B2 (en) 1981-09-15
FI71305B (fi) 1986-09-09
ES478228A1 (es) 1979-05-16
NZ189776A (en) 1980-08-26
YU42300B (en) 1988-08-31
CS208774B2 (en) 1981-09-15
AU4469379A (en) 1979-09-06
CA1136158A (en) 1982-11-23
IL56734A0 (en) 1979-05-31
ZA79989B (en) 1980-04-30
US4258058A (en) 1981-03-24
HU183085B (en) 1984-04-28
EP0004011B1 (de) 1981-04-01
JPS54122250A (en) 1979-09-21
AT367745B (de) 1982-07-26
DD142334A5 (de) 1980-06-18
PT69295A (de) 1979-03-01
FI790727A (fi) 1979-09-05
SU1097194A3 (ru) 1984-06-07
PL223895A1 (ja) 1981-05-22
SU1052157A3 (ru) 1983-10-30
DE2809377A1 (de) 1979-09-13
PL213847A1 (ja) 1980-12-01
PL124924B1 (en) 1983-03-31

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