JPS57131759A - 2-oxoazetidine derivative, its preparation and use - Google Patents

2-oxoazetidine derivative, its preparation and use

Info

Publication number
JPS57131759A
JPS57131759A JP56196078A JP19607881A JPS57131759A JP S57131759 A JPS57131759 A JP S57131759A JP 56196078 A JP56196078 A JP 56196078A JP 19607881 A JP19607881 A JP 19607881A JP S57131759 A JPS57131759 A JP S57131759A
Authority
JP
Japan
Prior art keywords
oxoazetidine
preparation
formulai
acylated
protected
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP56196078A
Other languages
English (en)
Inventor
Taisuke Matsuo
Hironaga Masuya
Noriyoshi Noguchi
Michihiko Ochiai
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda Pharmaceutical Co Ltd
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/JP1980/000296 external-priority patent/WO1982001872A1/ja
Priority claimed from PCT/JP1981/000102 external-priority patent/WO1982003858A1/ja
Priority claimed from PCT/JP1981/000192 external-priority patent/WO1983000690A1/ja
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Priority to JP56196078A priority Critical patent/JPS57131759A/ja
Publication of JPS57131759A publication Critical patent/JPS57131759A/ja
Pending legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D205/00Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D205/00Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • C07D205/085Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a nitrogen atom directly attached in position 3
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D205/00Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • C07D205/09Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a sulfur atom directly attached in position 4
    • C07D205/095Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a sulfur atom directly attached in position 4 and with a nitrogen atom directly attached in position 3
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02Silicon compounds
    • C07F7/08Compounds having one or more C—Si linkages
    • C07F7/0803Compounds with Si-C or Si-Si linkages
    • C07F7/081Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te
    • C07F7/0812Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te comprising a heterocyclic ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02Silicon compounds
    • C07F7/08Compounds having one or more C—Si linkages
    • C07F7/10Compounds having one or more C—Si linkages containing nitrogen having a Si-N linkage
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/568Four-membered rings
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
JP56196078A 1980-12-05 1981-12-04 2-oxoazetidine derivative, its preparation and use Pending JPS57131759A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP56196078A JPS57131759A (en) 1980-12-05 1981-12-04 2-oxoazetidine derivative, its preparation and use

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
PCT/JP1980/000296 WO1982001872A1 (en) 1980-12-05 1980-12-05 Azetidine derivatives and process for their preparation
PCT/JP1981/000102 WO1982003858A1 (fr) 1981-04-30 1981-04-30 Derives d'azetidine et procede de preparation
PCT/JP1981/000192 WO1983000690A1 (en) 1981-08-25 1981-08-25 Azetidine derivatives and process for their preparation
JP56196078A JPS57131759A (en) 1980-12-05 1981-12-04 2-oxoazetidine derivative, its preparation and use

Publications (1)

Publication Number Publication Date
JPS57131759A true JPS57131759A (en) 1982-08-14

Family

ID=27303167

Family Applications (1)

Application Number Title Priority Date Filing Date
JP56196078A Pending JPS57131759A (en) 1980-12-05 1981-12-04 2-oxoazetidine derivative, its preparation and use

Country Status (26)

Country Link
US (1) US4822790A (ja)
EP (1) EP0053815B1 (ja)
JP (1) JPS57131759A (ja)
KR (1) KR880001564B1 (ja)
AT (3) ATE13178T1 (ja)
AU (1) AU551463B2 (ja)
CH (1) CH656122A5 (ja)
DE (2) DE3170437D1 (ja)
DK (1) DK534381A (ja)
ES (2) ES507716A0 (ja)
FI (1) FI79528C (ja)
FR (1) FR2495612A1 (ja)
GB (1) GB2091723B (ja)
HU (1) HU189545B (ja)
IE (1) IE53451B1 (ja)
IL (1) IL64314A (ja)
IT (1) IT1146726B (ja)
LU (1) LU83820A1 (ja)
MX (1) MX7096E (ja)
NL (1) NL8105468A (ja)
NO (1) NO160297C (ja)
NZ (1) NZ199168A (ja)
PT (1) PT74087B (ja)
SE (1) SE8107273L (ja)
SU (2) SU1662348A3 (ja)
WO (1) WO1982002042A1 (ja)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS588060A (ja) * 1981-06-29 1983-01-18 イ−・ア−ル・スクイブ・アンド・サンズ・インコ−ポレイテツド アリ−ルチオアゼチジノンスルホン酸塩類
JPS5823662A (ja) * 1981-07-16 1983-02-12 イ−・ア−ル・スクイブ・アンド・サンズ・インコ−ポレイテツド 4−置換アゼチジノンスルホン酸塩誘導体
US4771045A (en) * 1982-05-31 1988-09-13 Takeda Chemical Industries, Ltd. 2-oxozetidinone derivatives, their production and use

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ199828A (en) * 1981-03-30 1985-11-08 Squibb & Sons Inc 4-substituted mercapto-2-oxo-1-azetidine-sulphonic acid derivatives and pharmaceutical compositions
US4734496A (en) * 1981-05-29 1988-03-29 E. R. Squibb & Sons, Inc. 4-amino derivatives of 2-oxo-1-azetidinesulfonic acid salts
EP0076758B1 (en) * 1981-10-05 1987-01-07 E.R. Squibb & Sons, Inc. 4-ether derivatives of 2-azetidinone-1-sulfonic acids
AU564150B2 (en) * 1982-04-30 1987-08-06 Takeda Chemical Industries Ltd. 1-sulfo-2-azetidinone derivatives
JPS5916888A (ja) * 1982-07-20 1984-01-28 Takeda Chem Ind Ltd 1−スルホ−2−アゼチジノン誘導体およびその製造法
US4681937A (en) * 1982-09-27 1987-07-21 E. R. Squibb & Sons, Inc. 3-acylamino-2-oxo-1-azetidinyl esters of phosphonic acids, phosphoric acid and phosphoric acid esters
JPS59101485A (ja) * 1982-11-29 1984-06-12 Otsuka Chem Co Ltd アセチジノン誘導体
DE3342929A1 (de) * 1983-11-26 1985-06-05 Bayer Ag, 5090 Leverkusen Ss-lactamantibiotika, verfahren zu deren herstellung sowie ihre verwendung als arzneimittel
US4883869A (en) * 1984-12-20 1989-11-28 The Upjohn Company Novel beta-lactams containing amino acid substituents
US5006650A (en) * 1987-02-11 1991-04-09 The Upjohn Company Novel N-1 substituted beta-lactams as antibiotics
WO1988006587A1 (en) * 1987-02-27 1988-09-07 The Upjohn Company ANTIBIOTIC beta-LACTAMS CONTAINING A PYRIDONE CARBOXYLIC ACID OR ACID DERIVATIVE
CA1317298C (en) * 1987-03-03 1993-05-04 Upjohn Company (The) Antibiotic sulfonylaminocarbonyl activated .beta.-lactams
US5015737A (en) * 1987-07-22 1991-05-14 The Upjohn Company Therapeutically useful beta-lactams
AU4133697A (en) * 1996-09-23 1998-04-14 Synphar Laboratories, Inc. 3,4-disubstituted azetidin-2-one derivatives useful as cysteine proteinase regulators

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS56125362A (en) * 1980-02-07 1981-10-01 Squibb & Sons Inc Beta lactam antibiotic and manufacture

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6046955B2 (ja) * 1977-12-30 1985-10-18 武田薬品工業株式会社 抗生物質g−6302
JPS5549394A (en) * 1978-10-03 1980-04-09 Takeda Chem Ind Ltd Antibiotic substance sb-72310
US4260627A (en) * 1978-10-24 1981-04-07 Merck & Co., Inc. 1-, 6- And 2-substituted-1-carba-2-penem-3-carboxylic acids
CA1338538C (en) * 1979-06-08 1996-08-20 Taisuke Matsuo 1-sulfo-2-oxoazetidine derivatives and their production
CA1242188A (en) * 1979-06-08 1988-09-20 Takeda Pharmaceutical Company Limited 3-methoxy-2-oxoazetidine derivatives and their production
NZ199828A (en) * 1981-03-30 1985-11-08 Squibb & Sons Inc 4-substituted mercapto-2-oxo-1-azetidine-sulphonic acid derivatives and pharmaceutical compositions
JPS588060A (ja) * 1981-06-29 1983-01-18 イ−・ア−ル・スクイブ・アンド・サンズ・インコ−ポレイテツド アリ−ルチオアゼチジノンスルホン酸塩類
FR2509726B1 (ja) * 1981-07-16 1984-04-27 Squibb & Sons Inc
FR2515182B1 (fr) * 1981-10-23 1986-05-09 Roussel Uclaf Nouveaux produits derives de l'acide 3-amino 2-oxo azetidine 1-sulfamique, leur procede de preparation, leur application comme medicaments et les produits intermediaires necessaires a leur preparation

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS56125362A (en) * 1980-02-07 1981-10-01 Squibb & Sons Inc Beta lactam antibiotic and manufacture

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS588060A (ja) * 1981-06-29 1983-01-18 イ−・ア−ル・スクイブ・アンド・サンズ・インコ−ポレイテツド アリ−ルチオアゼチジノンスルホン酸塩類
JPS5823662A (ja) * 1981-07-16 1983-02-12 イ−・ア−ル・スクイブ・アンド・サンズ・インコ−ポレイテツド 4−置換アゼチジノンスルホン酸塩誘導体
US4771045A (en) * 1982-05-31 1988-09-13 Takeda Chemical Industries, Ltd. 2-oxozetidinone derivatives, their production and use

Also Published As

Publication number Publication date
DE3170437D1 (en) 1985-06-13
US4822790A (en) 1989-04-18
HU189545B (en) 1986-07-28
IL64314A (en) 1988-06-30
SE8107273L (sv) 1982-06-06
DK534381A (da) 1982-06-06
ATE13178T1 (de) 1985-05-15
CH656122A5 (de) 1986-06-13
FI79528B (fi) 1989-09-29
IL64314A0 (en) 1982-02-28
AT380471B (de) 1986-05-26
MX7096E (es) 1987-06-19
ATA520781A (de) 1985-07-15
ES8301915A1 (es) 1982-12-16
AT379800B (de) 1986-02-25
ATA170384A (de) 1985-10-15
IT1146726B (it) 1986-11-19
ES507716A0 (es) 1982-12-16
KR880001564B1 (ko) 1988-08-22
AU7831381A (en) 1982-06-10
NO814113L (no) 1982-06-07
IT8168585A0 (it) 1981-12-04
EP0053815A1 (en) 1982-06-16
SU1531852A3 (ru) 1989-12-23
FR2495612A1 (fr) 1982-06-11
NO160297C (no) 1989-04-05
WO1982002042A1 (en) 1982-06-24
NO160297B (no) 1988-12-27
NZ199168A (en) 1985-08-30
SU1662348A3 (ru) 1991-07-07
AU551463B2 (en) 1986-05-01
GB2091723A (en) 1982-08-04
FR2495612B1 (ja) 1984-06-01
ES513420A0 (es) 1983-04-01
NL8105468A (nl) 1982-07-01
ES8305325A1 (es) 1983-04-01
FI79528C (fi) 1990-01-10
KR830007549A (ko) 1983-10-21
IE812859L (en) 1982-06-05
FI813851L (fi) 1982-06-06
PT74087B (en) 1983-05-23
EP0053815B1 (en) 1985-05-08
DE3148020A1 (de) 1982-10-21
LU83820A1 (fr) 1982-05-07
IE53451B1 (en) 1988-11-23
PT74087A (en) 1982-01-01
GB2091723B (en) 1985-06-12

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