JPS5610198A - Phosphonic acid derivative - Google Patents

Phosphonic acid derivative

Info

Publication number
JPS5610198A
JPS5610198A JP8441279A JP8441279A JPS5610198A JP S5610198 A JPS5610198 A JP S5610198A JP 8441279 A JP8441279 A JP 8441279A JP 8441279 A JP8441279 A JP 8441279A JP S5610198 A JPS5610198 A JP S5610198A
Authority
JP
Japan
Prior art keywords
formula
acid derivative
phosphonic acid
gram
condensing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP8441279A
Other languages
Japanese (ja)
Other versions
JPS6356233B2 (en
Inventor
Kazuo Kikazawa
Mineharu Hiiragi
Kikuo Wakizaka
Shigeru Yamabe
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aska Pharmaceutical Co Ltd
Original Assignee
Grelan Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Grelan Pharmaceutical Co Ltd filed Critical Grelan Pharmaceutical Co Ltd
Priority to JP8441279A priority Critical patent/JPS5610198A/en
Publication of JPS5610198A publication Critical patent/JPS5610198A/en
Publication of JPS6356233B2 publication Critical patent/JPS6356233B2/ja
Granted legal-status Critical Current

Links

Classifications

    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Abstract

NEW MATERIAL:A phosphonic acid derivative of formula I (R is thienyl or substituted phenyl).
EXAMPLE: 1-(β-2-Thienylalanyl)aminoethylphosphonic acid.
USE: Antibacterial agent effective to gram-positive and gram-negative bacteria.
PROCESS: The compound of formula I is prepared, e.g. by (1) condensing a protected amino acid of formula II (A is protecting group) or its reactive detivative with an ester of aminoethylphosphonic acid of formula III, in, e.g. a mixed solvent of dimethylformamide and dichloromethane, in the presence of a condensing agent such as dicyclohexylcarbodiimide, and (2) removing the protecting groups and at the same time hydrolyzing the reaction product.
COPYRIGHT: (C)1981,JPO&Japio
JP8441279A 1979-07-05 1979-07-05 Phosphonic acid derivative Granted JPS5610198A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP8441279A JPS5610198A (en) 1979-07-05 1979-07-05 Phosphonic acid derivative

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP8441279A JPS5610198A (en) 1979-07-05 1979-07-05 Phosphonic acid derivative

Publications (2)

Publication Number Publication Date
JPS5610198A true JPS5610198A (en) 1981-02-02
JPS6356233B2 JPS6356233B2 (en) 1988-11-07

Family

ID=13829867

Family Applications (1)

Application Number Title Priority Date Filing Date
JP8441279A Granted JPS5610198A (en) 1979-07-05 1979-07-05 Phosphonic acid derivative

Country Status (1)

Country Link
JP (1) JPS5610198A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4908162A (en) * 1988-11-22 1990-03-13 David Rubin Method of making triple bonded unsaturated fatty acids

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4908162A (en) * 1988-11-22 1990-03-13 David Rubin Method of making triple bonded unsaturated fatty acids

Also Published As

Publication number Publication date
JPS6356233B2 (en) 1988-11-07

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