JPS54128592A - Cephalosporin derivatives and its preparation - Google Patents

Cephalosporin derivatives and its preparation

Info

Publication number
JPS54128592A
JPS54128592A JP3606078A JP3606078A JPS54128592A JP S54128592 A JPS54128592 A JP S54128592A JP 3606078 A JP3606078 A JP 3606078A JP 3606078 A JP3606078 A JP 3606078A JP S54128592 A JPS54128592 A JP S54128592A
Authority
JP
Japan
Prior art keywords
formula
compound
group
reacted
lower alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP3606078A
Other languages
Japanese (ja)
Inventor
Masao Seki
Fumio Kai
Toshinori Saito
Yuuzou Kazuno
Keinosuke Miyauchi
Takahiro Ishii
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Meiji Seika Kaisha Ltd
Original Assignee
Meiji Seika Kaisha Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Meiji Seika Kaisha Ltd filed Critical Meiji Seika Kaisha Ltd
Priority to JP3606078A priority Critical patent/JPS54128592A/en
Publication of JPS54128592A publication Critical patent/JPS54128592A/en
Pending legal-status Critical Current

Links

Classifications

    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

NEW MATERIAL:A compound of formula I: [R1 is 2-thienyl group, formula II (R3 is H or lower alkyl group); R2 is formula III (R4, R5, and R6 are H or lower alkyl groups; n is an integer), etc,; NH2 group in R2 may be protected] and its salt, a compound of formulas IV, and a compound of formula V: (R1 is group of formula II).
EXAMPLE: 7-(2-Thienyl)acetamido-3-(5-piperazinocarbonyl-1,3,4-thiadiazole-2- ylthiomethyl)-3-cephem-4-carboxylic acid.
USE: Antibacterials and intermediates for their synthesis effective for Gram-positive bacteria, durable for a long time in a small dose.
PROCESS: A compound of formula is reacted with a novel compound of formula VI to give a compound of formula I, and, if necessary, the protecting group is removed. Alternatively, a compound of formula IV is reacted with a compound of the formula R1-CH2-COOH or its reactive derivative.
COPYRIGHT: (C)1979,JPO&Japio
JP3606078A 1978-03-30 1978-03-30 Cephalosporin derivatives and its preparation Pending JPS54128592A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP3606078A JPS54128592A (en) 1978-03-30 1978-03-30 Cephalosporin derivatives and its preparation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP3606078A JPS54128592A (en) 1978-03-30 1978-03-30 Cephalosporin derivatives and its preparation

Publications (1)

Publication Number Publication Date
JPS54128592A true JPS54128592A (en) 1979-10-05

Family

ID=12459166

Family Applications (1)

Application Number Title Priority Date Filing Date
JP3606078A Pending JPS54128592A (en) 1978-03-30 1978-03-30 Cephalosporin derivatives and its preparation

Country Status (1)

Country Link
JP (1) JPS54128592A (en)

Similar Documents

Publication Publication Date Title
JPS5686188A (en) 7-acylamino-3-substituted cephalosporanic acid derivative and its preparation
JPS5492987A (en) Cephalosporanic acid derivative, its salt, or their preparation, and preventives and remedies for microbisms consisting mainly of them
JPS5498795A (en) Cephalosporin derivative and its preparation
JPS55105689A (en) Novel cephem and cepham compounds, their preparation and preventive and remedy for microbism
JPS5777689A (en) Novel cephen compound, or its salt, its preparation, and preventive it as active ingredient
JPS56131565A (en) 4-substituted-2-oxoazetidine compound and its preparation
JPS56125392A (en) Cepham and cephem compound and preparation thereof
JPS5692893A (en) Novel cephem compound, its preparation, and preventive and remedy for bacteriosis containing said compound as effective component
JPS5547688A (en) Novel cephem compound and its preparation
ES8705362A1 (en) 2-Hydroxy-3-aryloxypropyl or 2-hydroxy-2-benzofuranyl ethyl tertiary amine having an anti-hyperglycaemic and/or anti-obesity activity.
JPS54128591A (en) Cephalosporin analog
JPS5533500A (en) 3,7-disubstituted-3-cephem-4-carboxylic acid, its salt, their preparation, and preventive and remedy for microbism
JPS554337A (en) Cephalosporin analogs
JPS5746990A (en) Novel cephalexin derivative and its preparation
JPS54128592A (en) Cephalosporin derivatives and its preparation
JPS54117493A (en) 3,7-disubstituted-3-cephem-4-carboxylic acid compound, its salt, its preparation, and preventives and remedies for microbism consisting mainly of them
JPS56142282A (en) Penem-3-carboxylic acid derivative and its preparation
JPS56115788A (en) Azetidinone derivative and its preparation
JPS5721400A (en) Novel fortimicin derivative
JPS5549384A (en) Novel antibacterial compound
JPS5745190A (en) Novel 7alpha-methoxycephalosporin
JPS5547690A (en) Cephem compound, its salt, their preparation, and preventives and remedies for microbism comprising them as active constituents
JPS54103890A (en) Novel antibacteral compound
JPS54106495A (en) Cephem derivative
JPS572289A (en) Production of penem-3-carboxylic derivative