JPS54128592A - Cephalosporin derivatives and its preparation - Google Patents
Cephalosporin derivatives and its preparationInfo
- Publication number
- JPS54128592A JPS54128592A JP3606078A JP3606078A JPS54128592A JP S54128592 A JPS54128592 A JP S54128592A JP 3606078 A JP3606078 A JP 3606078A JP 3606078 A JP3606078 A JP 3606078A JP S54128592 A JPS54128592 A JP S54128592A
- Authority
- JP
- Japan
- Prior art keywords
- formula
- compound
- group
- reacted
- lower alkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Cephalosporin Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
NEW MATERIAL:A compound of formula I: [R1 is 2-thienyl group, formula II (R3 is H or lower alkyl group); R2 is formula III (R4, R5, and R6 are H or lower alkyl groups; n is an integer), etc,; NH2 group in R2 may be protected] and its salt, a compound of formulas IV, and a compound of formula V: (R1 is group of formula II).
EXAMPLE: 7-(2-Thienyl)acetamido-3-(5-piperazinocarbonyl-1,3,4-thiadiazole-2- ylthiomethyl)-3-cephem-4-carboxylic acid.
USE: Antibacterials and intermediates for their synthesis effective for Gram-positive bacteria, durable for a long time in a small dose.
PROCESS: A compound of formula is reacted with a novel compound of formula VI to give a compound of formula I, and, if necessary, the protecting group is removed. Alternatively, a compound of formula IV is reacted with a compound of the formula R1-CH2-COOH or its reactive derivative.
COPYRIGHT: (C)1979,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP3606078A JPS54128592A (en) | 1978-03-30 | 1978-03-30 | Cephalosporin derivatives and its preparation |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP3606078A JPS54128592A (en) | 1978-03-30 | 1978-03-30 | Cephalosporin derivatives and its preparation |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS54128592A true JPS54128592A (en) | 1979-10-05 |
Family
ID=12459166
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP3606078A Pending JPS54128592A (en) | 1978-03-30 | 1978-03-30 | Cephalosporin derivatives and its preparation |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS54128592A (en) |
-
1978
- 1978-03-30 JP JP3606078A patent/JPS54128592A/en active Pending
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