JPS5569549A - Novel substrate for determination of enzyme activity - Google Patents

Novel substrate for determination of enzyme activity

Info

Publication number
JPS5569549A
JPS5569549A JP14146378A JP14146378A JPS5569549A JP S5569549 A JPS5569549 A JP S5569549A JP 14146378 A JP14146378 A JP 14146378A JP 14146378 A JP14146378 A JP 14146378A JP S5569549 A JPS5569549 A JP S5569549A
Authority
JP
Japan
Prior art keywords
compound
formula
determination
hydroxyaniline
gtp
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP14146378A
Other languages
English (en)
Other versions
JPS5649904B2 (ja
Inventor
Takeshi Nagasawa
Katsumasa Kuroiwa
Toshiyuki Takabayashi
Norimasa Takizawa
Kazuyo Hagiwara
Tadami Akatsuka
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
YATORON KK
Nitto Boseki Co Ltd
Mitsubishi Kagaku Iatron Inc
Original Assignee
YATORON KK
Nitto Boseki Co Ltd
Mitsubishi Kagaku Iatron Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by YATORON KK, Nitto Boseki Co Ltd, Mitsubishi Kagaku Iatron Inc filed Critical YATORON KK
Priority to JP14146378A priority Critical patent/JPS5569549A/ja
Priority to GB7916858A priority patent/GB2034690B/en
Priority to DE2920292A priority patent/DE2920292C3/de
Priority to CH477579A priority patent/CH640826A5/de
Priority to SE7905009A priority patent/SE445829B/sv
Priority to FR7915353A priority patent/FR2441609A1/fr
Priority to US06/094,072 priority patent/US4281181A/en
Publication of JPS5569549A publication Critical patent/JPS5569549A/ja
Priority to US06/245,817 priority patent/US4336331A/en
Publication of JPS5649904B2 publication Critical patent/JPS5649904B2/ja
Granted legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/02Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C237/04Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/48Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90Enzymes; Proenzymes
    • G01N2333/91Transferases (2.)
    • G01N2333/91045Acyltransferases (2.3)
    • G01N2333/91074Aminoacyltransferases (general) (2.3.2)
    • G01N2333/9108Aminoacyltransferases (general) (2.3.2) with definite EC number (2.3.2.-)
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
JP14146378A 1978-11-16 1978-11-16 Novel substrate for determination of enzyme activity Granted JPS5569549A (en)

Priority Applications (8)

Application Number Priority Date Filing Date Title
JP14146378A JPS5569549A (en) 1978-11-16 1978-11-16 Novel substrate for determination of enzyme activity
GB7916858A GB2034690B (en) 1978-11-16 1979-05-15 - y - glutamyl - 3 - carboxy - 4-hydroxyanilide and salts thereof
DE2920292A DE2920292C3 (de) 1978-11-16 1979-05-18 L-γ -Glutamyl-3-carboxy-4-hydroxyanilid und dessen Säureadditions- oder Alkalisalze, Verfahren zu deren Herstellung und deren Verwendung zur Bestimmung der Aktivität von γ-Glutamyltranspeptidase
CH477579A CH640826A5 (de) 1978-11-16 1979-05-22 L-gamma-glutamyl-3-carboxy-4-hydroxyanilid und dessen salze, verfahren zu dessen herstellung und dessen verwendung zur bestimmung der aktivitaet von gamma-glutamyltranspeptidase.
SE7905009A SE445829B (sv) 1978-11-16 1979-06-08 Ny l-gamma-glutamyl-3-karboxi-4-hydroxianilid och salter derav
FR7915353A FR2441609A1 (fr) 1978-11-16 1979-06-15 Nouveau l-gamma-glutamyl-3-carboxy-4-hydroxyanilide et ses sels et leur application a la determination de l'activite de g-glutamyl-transpeptidase
US06/094,072 US4281181A (en) 1978-11-16 1979-11-14 Novel L-γ-glutamyl-3-carboxy-4-hydroxyanilide and salts thereof
US06/245,817 US4336331A (en) 1978-11-16 1981-03-20 Method for assaying the activity of γ-glutamyl transpeptidase in serum

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP14146378A JPS5569549A (en) 1978-11-16 1978-11-16 Novel substrate for determination of enzyme activity

Publications (2)

Publication Number Publication Date
JPS5569549A true JPS5569549A (en) 1980-05-26
JPS5649904B2 JPS5649904B2 (ja) 1981-11-25

Family

ID=15292461

Family Applications (1)

Application Number Title Priority Date Filing Date
JP14146378A Granted JPS5569549A (en) 1978-11-16 1978-11-16 Novel substrate for determination of enzyme activity

Country Status (7)

Country Link
US (2) US4281181A (ja)
JP (1) JPS5569549A (ja)
CH (1) CH640826A5 (ja)
DE (1) DE2920292C3 (ja)
FR (1) FR2441609A1 (ja)
GB (1) GB2034690B (ja)
SE (1) SE445829B (ja)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6425749A (en) * 1987-04-10 1989-01-27 Shino Test Corp Substrate for measuring enzyme activity and method for measuring enzyme activity using said substrate

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0052296B1 (en) * 1980-11-12 1984-06-27 Mitsubishi Kasei Corporation Glutamine derivatives usable for curing immune diseases, methods for their preparation and compositions comprising said derivatives
DE3176589D1 (en) * 1980-12-02 1988-02-11 Health Lab Service Board Method for the estimation of n-acylated primary aromatic amines
JPS5856695A (ja) * 1981-09-28 1983-04-04 Nitto Boseki Co Ltd 新規なトロンビン測定用基質
JPS5863399A (ja) * 1981-10-14 1983-04-15 Nitto Boseki Co Ltd 新規なプラスミン測定用基質
US4588836A (en) * 1982-09-01 1986-05-13 Toyo Jozo Kabushiki Kaisha Novel synthetic substrate and assay method using the same
DE3234478A1 (de) * 1982-09-17 1984-03-22 Boehringer Mannheim Gmbh, 6800 Mannheim Reagenz und verfahren zur bestimmung von (gamma)-glutamyltransferase
JPS60166657A (ja) * 1984-02-10 1985-08-29 Nitto Boseki Co Ltd アルギニル−3−カルボキシ−4−ヒドロキシアニリド
US5116730A (en) * 1988-06-15 1992-05-26 Board Of Governors Of Wayne State University Amino acid substituted 4-aminophenazones for measuring enzyme activity
FR2644697B1 (fr) * 1989-03-24 1992-05-15 Poudres & Explosifs Ste Nale Composes anesthesiques a duree d'action controlee et compositions pharmaceutiques les contenant
IT1244873B (it) * 1990-09-12 1994-09-12 Depha Team Srl Derivati dell'acido 5-aminosalicilico (5-asa) per la terapia delle infiammazioni croniche intestinali
US5474906A (en) * 1993-03-26 1995-12-12 Eiken Kagaku Kabushiki Kaisha Reagent for determining γ-glutamyl transpeptidase activity
US5847192A (en) * 1994-01-28 1998-12-08 Prolinx, Inc. Boronic compound complexing reagents and complexes
US5594151A (en) * 1994-01-28 1997-01-14 Prolinx, Inc. Phenylboronic acid complexing reagents derived from aminosalicylic acid
US5594111A (en) * 1994-01-28 1997-01-14 Prolinx, Inc. Phenylboronic acid complexes for bioconjugate preparation
US5852178A (en) * 1994-01-28 1998-12-22 Prolinx, Inc. Phenylboronic acid complexing reagents for conjugating biologically active molecules
US5777148A (en) * 1994-01-28 1998-07-07 Prolinx, Inc. Boronic compound complexing reagents and highly stable complexes
US5744627A (en) * 1994-01-28 1998-04-28 Prolinx, Inc. Boronic compound complexing reagents and complexes
US5837878A (en) * 1994-01-28 1998-11-17 Prolinx, Inc. Boronic compound complexing reagents and highly stable complexes
US5623055A (en) * 1994-01-28 1997-04-22 Prolinx, Inc. Phenylboronic acid complexes derived from aminosalicylic acid for bioconjugate preparation
US6156884A (en) * 1996-08-05 2000-12-05 Prolinx, Inc. Bifunctional boronic compound complexing reagents and complexes
US6075126A (en) * 1996-08-05 2000-06-13 Prolinx, Inc. Phenyldiboronic acid reagents and complexes
US10391038B2 (en) * 2008-02-08 2019-08-27 Colgate-Palmolive Company Tooth sealant
JP5685941B2 (ja) * 2008-10-03 2015-03-18 味の素株式会社 CaSRアゴニスト

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2891091A (en) * 1957-06-03 1959-06-16 Canadian Patents Dev Derivatives of para-aminosalicylic acid
US3383411A (en) * 1964-02-17 1968-05-14 Merck & Co Inc 4-alkanoylphenoxy-alkanoic acids
US3452086A (en) * 1966-04-29 1969-06-24 Bristol Myers Co Substituted tartranilic acid resolving agents
US3769173A (en) * 1972-08-21 1973-10-30 Warner Lambert Co Determination of gamma-glutamyl transpeptidase in biological fluids
AT331994B (de) * 1972-12-05 1976-09-10 Boehringer Mannheim Gmbh Verfahren zur bestimmung von delta-glutamyltranspeptidase
JPS584560B2 (ja) * 1976-06-01 1983-01-26 三共株式会社 鉄錯塩を用いた酵素活性測定法
JPS53147034A (en) * 1977-05-30 1978-12-21 Wako Pure Chem Ind Ltd Gamma-glutamyl-p-aminoanilide derivatives and process for their preparation
JPS54157691A (en) * 1978-06-01 1979-12-12 Nitto Boseki Co Ltd Novel substrate for measuring enzyme activity

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6425749A (en) * 1987-04-10 1989-01-27 Shino Test Corp Substrate for measuring enzyme activity and method for measuring enzyme activity using said substrate

Also Published As

Publication number Publication date
DE2920292A1 (de) 1980-05-22
SE445829B (sv) 1986-07-21
SE7905009L (sv) 1980-05-17
US4336331A (en) 1982-06-22
GB2034690A (en) 1980-06-11
DE2920292C3 (de) 1982-01-28
JPS5649904B2 (ja) 1981-11-25
GB2034690B (en) 1983-01-12
US4281181A (en) 1981-07-28
FR2441609A1 (fr) 1980-06-13
DE2920292B2 (de) 1981-02-19
CH640826A5 (de) 1984-01-31
FR2441609B1 (ja) 1984-05-11

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