JPS50121277A - - Google Patents

Info

Publication number
JPS50121277A
JPS50121277A JP49027442A JP2744274A JPS50121277A JP S50121277 A JPS50121277 A JP S50121277A JP 49027442 A JP49027442 A JP 49027442A JP 2744274 A JP2744274 A JP 2744274A JP S50121277 A JPS50121277 A JP S50121277A
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP49027442A
Other languages
Japanese (ja)
Other versions
JPS5726506B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Priority to JP2744274A priority Critical patent/JPS5726506B2/ja
Priority to AT772674A priority patent/AT347054B/de
Priority to CS7400006578A priority patent/CS180644B2/cs
Priority to GB4188274A priority patent/GB1434694A/en
Priority to DE2446005A priority patent/DE2446005C2/de
Priority to SE7412140A priority patent/SE420717B/xx
Priority to CH1304774A priority patent/CH603559A5/xx
Priority to DK510374A priority patent/DK148305C/da
Priority to FR7432580A priority patent/FR2245375B1/fr
Priority to CA210,223A priority patent/CA1027114A/en
Priority to HU74TA323A priority patent/HU173783B/hu
Priority to BE148990A priority patent/BE820451A/xx
Priority to NLAANVRAGE7412837,A priority patent/NL179289C/xx
Priority to ES430495A priority patent/ES430495A1/es
Priority to NO743538A priority patent/NO143218C/no
Priority to FI2847/74A priority patent/FI61028C/fi
Priority to AT138075A priority patent/AT348693B/de
Priority to AU78594/75A priority patent/AU484633B2/en
Priority to ZA00751306A priority patent/ZA751306B/xx
Priority to CA221,126A priority patent/CA1072953A/en
Priority to US05/555,126 priority patent/US3972859A/en
Priority to NLAANVRAGE7502564,A priority patent/NL181658C/xx
Priority to CS7500001485A priority patent/CS186284B2/cs
Priority to DE2509783A priority patent/DE2509783C2/de
Priority to SE7502520A priority patent/SE420718B/xx
Priority to FR7507065A priority patent/FR2262995B1/fr
Priority to GB9539/75A priority patent/GB1498048A/en
Priority to NO750763A priority patent/NO145691C/no
Priority to ES435405A priority patent/ES435405A1/es
Priority to DK092775A priority patent/DK149862C/da
Priority to CH294775A priority patent/CH615661A5/de
Priority to BE154128A priority patent/BE826430A/xx
Priority to HU75TA1346A priority patent/HU174077B/hu
Priority to FI750682A priority patent/FI60859C/fi
Priority to US05/595,308 priority patent/US4008209A/en
Publication of JPS50121277A publication Critical patent/JPS50121277A/ja
Priority to HK155/79A priority patent/HK15579A/xx
Publication of JPS5726506B2 publication Critical patent/JPS5726506B2/ja
Priority to NL930015C priority patent/NL930015I2/nl
Priority to NL930121C priority patent/NL930121I1/nl
Priority to NO1994010C priority patent/NO1994010I1/no
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1002—Tetrapeptides with the first amino acid being neutral
    • C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/23—Luteinising hormone-releasing hormone [LHRH]; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/13—Luteinizing hormone-releasing hormone; related peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2744274A 1973-09-29 1974-03-08 Expired JPS5726506B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Priority Applications (39)

Application Number Priority Date Filing Date Title
JP2744274A JPS5726506B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1974-03-08 1974-03-08
AT772674A AT347054B (de) 1973-09-29 1974-09-25 Verfahren zur herstellung von neuen nonapeptidamid-derivaten
CS7400006578A CS180644B2 (en) 1973-09-29 1974-09-25 Process for preparing nonapeptides
GB4188274A GB1434694A (en) 1973-09-29 1974-09-26 Nonapeptide amides
DE2446005A DE2446005C2 (de) 1973-09-29 1974-09-26 Nonapeptidamide und Verfahren zu ihrer Herstellung
SE7412140A SE420717B (sv) 1973-09-29 1974-09-26 Sett att framstella nya nonapeptidamidderivat med ovulationsinducerande aktivitet
CH1304774A CH603559A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1973-09-29 1974-09-26
DK510374A DK148305C (da) 1973-09-29 1974-09-27 Analogifremgangsmaade til fremstilling af et lh-rh-analogt nonapeptidamidderivat eller et salt eller metalkompleks deraf
FR7432580A FR2245375B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1973-09-29 1974-09-27
CA210,223A CA1027114A (en) 1973-09-29 1974-09-27 Nonapeptide amides
HU74TA323A HU173783B (hu) 1973-09-29 1974-09-27 Sposob poluchenija monopeptidaminov
BE148990A BE820451A (fr) 1973-09-29 1974-09-27 Nouveaux amides nonapeptides
NLAANVRAGE7412837,A NL179289C (nl) 1973-09-29 1974-09-27 Werkwijze ter bereiding van nonapeptide-amidederivaten, en farmaceutische preparaten met ovulatieopwekkende werking daaruit.
ES430495A ES430495A1 (es) 1973-09-29 1974-09-28 Un metodo para preparar amidas de monapeptidos.
NO743538A NO143218C (no) 1973-09-29 1974-09-30 Analogifremgangsmaate til fremstilling av nonapeptidamider med lh-rh aktivitet
FI2847/74A FI61028C (fi) 1973-09-29 1974-09-30 Foerfarande foer framstaellning av ovulation framkallande nonapeptidamidderivat
AT138075A AT348693B (de) 1974-03-08 1975-02-24 Verfahren zur herstellung von neuen decapeptidamidderivaten
AU78594/75A AU484633B2 (en) 1974-03-08 1975-02-26 Decapeptide amides
CA221,126A CA1072953A (en) 1974-03-08 1975-03-03 Decapeptide amides
ZA00751306A ZA751306B (en) 1974-03-08 1975-03-03 Decapeptide amides
US05/555,126 US3972859A (en) 1974-03-08 1975-03-04 Novel decapeptide amide analogs of leuteinizing hormone-releasing hormone
NLAANVRAGE7502564,A NL181658C (nl) 1974-03-08 1975-03-04 Werkwijze ter bereiding van farmaceutische preparaten met een de ovulatie opwekkende werking en werkwijze ter bereiding van hierbij te gebruiken decapeptiden.
CS7500001485A CS186284B2 (en) 1974-03-08 1975-03-05 Method for producing decapeptide amides
DE2509783A DE2509783C2 (de) 1974-03-08 1975-03-06 Decapeptidamide und Verfahren zu deren Herstellung
SE7502520A SE420718B (sv) 1974-03-08 1975-03-06 Sett att framstella nya dekapeptidamidderivat med ovalationsinducerande aktivitet
FR7507065A FR2262995B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1974-03-08 1975-03-06
DK092775A DK149862C (da) 1974-03-08 1975-03-07 Analogifremgangsmaade til fremstilling af lh-rh-analoge dekapeptidamider eller et salt eller et metalkompleks deraf
NO750763A NO145691C (no) 1974-03-08 1975-03-07 Analogifremgangsmaate til fremstilling av terapeutisk virksomme decapeptidamider
ES435405A ES435405A1 (es) 1974-03-08 1975-03-07 Un metodo para producir derivados de amidas de decapepti- dos.
GB9539/75A GB1498048A (en) 1974-03-08 1975-03-07 Decapeptide amides
CH294775A CH615661A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1974-03-08 1975-03-07
BE154128A BE826430A (fr) 1974-03-08 1975-03-07 Amides de decapeptides
HU75TA1346A HU174077B (hu) 1974-03-08 1975-03-07 Sposob poluchenija proizvodnykh dekapeptidamidakh
FI750682A FI60859C (fi) 1974-03-08 1975-03-10 Foerfarande foer framstaellning av ovulationsframkallande dekapeptidamidderivat
US05/595,308 US4008209A (en) 1973-09-29 1975-07-11 Nonapeptide amide analogs of luteinizing releasing hormone
HK155/79A HK15579A (en) 1973-09-29 1979-03-22 Nonapeptide amides
NL930015C NL930015I2 (nl) 1973-09-29 1993-02-23 Werkwijze ter bereiding van nonapepide-aminederivaten, en farmaceutische preparaten met ovulatie-opwekkende werking daaruit.
NL930121C NL930121I1 (nl) 1973-09-29 1993-06-30 Werkwijze ter bereiding van nonapeptide-amidederivaten en farmaceutische preparaten met ovulatieopw ekkende werking daaruit
NO1994010C NO1994010I1 (no) 1973-09-29 1994-08-18 Leuprorelin

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2744274A JPS5726506B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1974-03-08 1974-03-08

Publications (2)

Publication Number Publication Date
JPS50121277A true JPS50121277A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1975-09-23
JPS5726506B2 JPS5726506B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1982-06-04

Family

ID=12221217

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2744274A Expired JPS5726506B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1973-09-29 1974-03-08

Country Status (18)

Country Link
US (1) US3972859A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (1) JPS5726506B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AT (1) AT348693B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
BE (1) BE826430A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CA (1) CA1072953A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CH (1) CH615661A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CS (1) CS186284B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (1) DE2509783C2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DK (1) DK149862C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ES (1) ES435405A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FI (1) FI60859C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FR (1) FR2262995B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
GB (1) GB1498048A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
HU (1) HU174077B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NL (1) NL181658C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NO (1) NO145691C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
SE (1) SE420718B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ZA (1) ZA751306B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5148659A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * 1974-08-09 1976-04-26 Hoechst Ag
JPS55164663A (en) * 1979-06-11 1980-12-22 Syntex Inc Nonapeptide and decapeptide derivatives of progesterone release hormone and its manufacture
JPS57118512A (en) * 1980-11-18 1982-07-23 Syntex Inc Microencapsulation of water-soluble polypeptide
JPS57150609A (en) * 1981-02-16 1982-09-17 Ici Ltd Pharmaceutical composition, heterogeneous copolymer comprising lactic acid and glycolic acid units and manufacture
JPS58125819U (ja) * 1982-02-19 1983-08-26 名伸電機株式会社 積算電力量計用パツキン
JP2013520440A (ja) * 2010-02-19 2013-06-06 ペプタデルム エスピー．ゼット．オー．オー． 環式テトラペプチド及びその治療応用

Families Citing this family (100)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU497512B2 (en) * 1975-04-15 1978-12-14 Ici Australia Limited Nona and deca-peptides
US4215038A (en) * 1978-10-16 1980-07-29 The Salk Institute For Biological Studies Peptides which inhibit gonadal function
US4318905A (en) * 1980-06-23 1982-03-09 Syntex (U.S.A.) Inc. Nonapeptide and decapeptide agonists of luteinizing hormone releasing hormone containing heterocyclic amino acid residues
ZA815447B (en) * 1980-08-29 1982-08-25 Salk Inst For Biological Studi Peptides affecting gonadal function
US4675189A (en) * 1980-11-18 1987-06-23 Syntex (U.S.A.) Inc. Microencapsulation of water soluble active polypeptides
AU549053B2 (en) * 1981-12-28 1986-01-09 Beckman Instruments, Inc. Synthetic peptides having pituitary growth hormone releasing activity
US4581169A (en) * 1982-12-21 1986-04-08 Syntex (U.S.A.) Inc. Nona-peptide and deca-peptide analogs of LHRH, useful as LHRH antagonists
US4667014A (en) * 1983-03-07 1987-05-19 Syntex (U.S.A.) Inc. Nonapeptide and decapeptide analogs of LHRH, useful as LHRH antagonists
US4481190A (en) * 1982-12-21 1984-11-06 Syntex (U.S.A.) Inc. Nonapeptide and decapeptide analogs of LHRH useful as LHRH antagonists
US4663435A (en) * 1982-12-06 1987-05-05 Merck & Co., Inc. Bridged cyclic hexapeptide somatostatin analogs
US4581168A (en) * 1983-02-21 1986-04-08 Sanofi Synthesis of hpGRF (Somatocrinin) in liquid phase and intermediate peptides
US4530920A (en) * 1983-11-07 1985-07-23 Syntex (U.S.A.) Inc. Nonapeptide and decapeptide analogs of LHRH, useful as LHRH agonist
US4897268A (en) * 1987-08-03 1990-01-30 Southern Research Institute Drug delivery system and method of making the same
JP2653255B2 (ja) 1990-02-13 1997-09-17 武田薬品工業株式会社 長期徐放型マイクロカプセル
CA2050425A1 (en) 1990-09-03 1992-03-04 Yoshiaki Uda Pharmaceutical composition and its mucous use
NO302481B1 (no) 1990-10-16 1998-03-09 Takeda Chemical Industries Ltd Polymer for et preparat med forlenget frigjöring, samt preparat med forlenget frigjöring
US6031003A (en) * 1991-08-23 2000-02-29 Nps Pharmaceuticals, Inc. Calcium receptor-active molecules
US5763569A (en) * 1991-08-23 1998-06-09 The Brigham And Women's Hospital, Inc Calcium receptor-active molecules
US6011068A (en) * 1991-08-23 2000-01-04 Nps Pharmaceuticals, Inc. Calcium receptor-active molecules
US5688938A (en) * 1991-08-23 1997-11-18 The Brigham & Women's Hospital, Inc. Calcium receptor-active molecules
US6313146B1 (en) 1991-08-23 2001-11-06 Nps Pharmaceuticals, Inc. Calcium receptor-active molecules
US5518730A (en) * 1992-06-03 1996-05-21 Fuisz Technologies Ltd. Biodegradable controlled release flash flow melt-spun delivery system
DK0582459T3 (da) 1992-08-07 1998-04-27 Takeda Chemical Industries Ltd Fremstilling af mikrokapsler af vandopløselige lægemidler
US5962314A (en) * 1993-02-23 1999-10-05 Nps Pharmaceuticals, Inc. Calcium receptor-active molecules
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US6103237A (en) * 1993-07-22 2000-08-15 Hybritech Incorporated Stable variant hK2 polypeptide
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US5837281A (en) 1995-03-17 1998-11-17 Takeda Chemical Industries, Ltd. Stabilized interface for iontophoresis
CA2192773C (en) 1995-12-15 2008-09-23 Hiroaki Okada Production of sustained-release preparation for injection
CA2192782C (en) 1995-12-15 2008-10-14 Nobuyuki Takechi Production of microspheres
ATE352537T1 (de) 1996-05-01 2007-02-15 Nps Pharma Inc Verbindungen, die auf anorganische ionen- rezeptoren wirken
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DE60030323T2 (de) 1999-12-24 2007-10-11 Genentech, Inc., South San Francisco Verfahren und verbindungen zur verlängerung der halbwertzeiten bei der ausscheidung von biowirksamen verbindungen
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US7968080B2 (en) 2003-08-20 2011-06-28 The Regents Of The University Of California Somatostatin analogs with inhibitory activity to growth hormone release
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NO145691C (no) 1982-05-12
JPS5726506B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1982-06-04
US3972859A (en) 1976-08-03
CA1072953A (en) 1980-03-04
DK149862B (da) 1986-10-13
AT348693B (de) 1979-02-26
NL181658C (nl) 1987-10-01
ES435405A1 (es) 1976-12-01
FI60859C (fi) 1982-04-13
DE2509783A1 (de) 1975-09-11
SE420718B (sv) 1981-10-26
ZA751306B (en) 1976-01-28
FR2262995A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1975-10-03
DK92775A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1975-09-09
NO145691B (no) 1982-02-01
NO750763L (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1975-09-09
FI60859B (fi) 1981-12-31
CS186284B2 (en) 1978-11-30
FR2262995B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1978-07-28
GB1498048A (en) 1978-01-18
BE826430A (fr) 1975-09-08
ATA138075A (de) 1978-07-15
NL7502564A (nl) 1975-09-10
AU7859475A (en) 1976-08-26
HU174077B (hu) 1979-10-28
SE7502520L (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1975-09-09
NL181658B (nl) 1987-05-04
DK149862C (da) 1987-06-15
CH615661A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1980-02-15
DE2509783C2 (de) 1983-02-17
FI750682A7 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1975-09-09

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