JPH11510488A5 - - Google Patents

Info

Publication number
JPH11510488A5
JPH11510488A5 JP1997506919A JP50691997A JPH11510488A5 JP H11510488 A5 JPH11510488 A5 JP H11510488A5 JP 1997506919 A JP1997506919 A JP 1997506919A JP 50691997 A JP50691997 A JP 50691997A JP H11510488 A5 JPH11510488 A5 JP H11510488A5
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP1997506919A
Other languages
English (en)
Japanese (ja)
Other versions
JP4174563B2 (ja
JPH11510488A (ja
Filing date
Publication date
Priority claimed from US08/505,606 external-priority patent/US5925351A/en
Application filed filed Critical
Publication of JPH11510488A publication Critical patent/JPH11510488A/ja
Publication of JPH11510488A5 publication Critical patent/JPH11510488A5/ja
Application granted granted Critical
Publication of JP4174563B2 publication Critical patent/JP4174563B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

JP50691997A 1995-07-21 1996-07-19 免疫学的疾患の処置のための治療剤としての可溶性リンホトキシン−βレセプターならびに抗リンホトキシンレセプターおよびリガンド抗体 Expired - Fee Related JP4174563B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/505,606 US5925351A (en) 1995-07-21 1995-07-21 Soluble lymphotoxin-β receptors and anti-lymphotoxin receptor and ligand antibodies as therapeutic agents for the treatment of immunological disease
US08/505,606 1995-07-21
PCT/US1996/012010 WO1997003687A1 (en) 1995-07-21 1996-07-19 SOLUBLE LYMPHOTOXIN-β RECEPTORS AND ANTI-LYMPHOTOXIN RECEPTOR AND LIGAND ANTIBODIES, AS THERAPEUTIC AGENTS FOR THE TREATMENT OF IMMUNOLOGICAL DISEASE

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2007161925A Division JP2007254488A (ja) 1995-07-21 2007-06-19 免疫学的疾患の処置のための治療剤としての可溶性リンホトキシン−βレセプターならびに抗リンホトキシンレセプターおよびリガンド抗体

Publications (3)

Publication Number Publication Date
JPH11510488A JPH11510488A (ja) 1999-09-14
JPH11510488A5 true JPH11510488A5 (enExample) 2004-08-26
JP4174563B2 JP4174563B2 (ja) 2008-11-05

Family

ID=24011046

Family Applications (3)

Application Number Title Priority Date Filing Date
JP50691997A Expired - Fee Related JP4174563B2 (ja) 1995-07-21 1996-07-19 免疫学的疾患の処置のための治療剤としての可溶性リンホトキシン−βレセプターならびに抗リンホトキシンレセプターおよびリガンド抗体
JP2007161925A Withdrawn JP2007254488A (ja) 1995-07-21 2007-06-19 免疫学的疾患の処置のための治療剤としての可溶性リンホトキシン−βレセプターならびに抗リンホトキシンレセプターおよびリガンド抗体
JP2011209921A Withdrawn JP2012041350A (ja) 1995-07-21 2011-09-26 免疫学的疾患の処置のための治療剤としての可溶性リンホトキシン−βレセプターならびに抗リンホトキシンレセプターおよびリガンド抗体

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2007161925A Withdrawn JP2007254488A (ja) 1995-07-21 2007-06-19 免疫学的疾患の処置のための治療剤としての可溶性リンホトキシン−βレセプターならびに抗リンホトキシンレセプターおよびリガンド抗体
JP2011209921A Withdrawn JP2012041350A (ja) 1995-07-21 2011-09-26 免疫学的疾患の処置のための治療剤としての可溶性リンホトキシン−βレセプターならびに抗リンホトキシンレセプターおよびリガンド抗体

Country Status (28)

Country Link
US (6) US5925351A (enExample)
EP (2) EP1488799A3 (enExample)
JP (3) JP4174563B2 (enExample)
KR (2) KR100493980B1 (enExample)
CN (3) CN1607005A (enExample)
AT (1) ATE279205T1 (enExample)
AU (1) AU715407B2 (enExample)
BG (1) BG63330B1 (enExample)
BR (1) BR9609716A (enExample)
CA (1) CA2227477A1 (enExample)
CZ (1) CZ298277B6 (enExample)
DE (1) DE69633624T2 (enExample)
DK (1) DK0840616T3 (enExample)
EA (3) EA005734B1 (enExample)
EE (1) EE04419B1 (enExample)
ES (1) ES2225889T3 (enExample)
FI (1) FI980122L (enExample)
HU (1) HU227508B1 (enExample)
MX (1) MX9800624A (enExample)
NO (2) NO327163B1 (enExample)
NZ (2) NZ503818A (enExample)
PL (1) PL186911B1 (enExample)
PT (1) PT840616E (enExample)
RO (1) RO121799B1 (enExample)
SI (1) SI0840616T1 (enExample)
SK (1) SK286409B6 (enExample)
TR (1) TR199800091T1 (enExample)
WO (1) WO1997003687A1 (enExample)

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US7255854B1 (en) * 1996-10-25 2007-08-14 Biogen, Inc. Use of lymphotoxin-β receptor blocking agents for the treatment of antibody mediated immunological diseases
DE69736244T2 (de) * 1996-10-25 2007-05-31 Biogen Idec Ma Inc., Cambridge Lösliche lymphotoxin-beta rezeptoren, anti-lymphotoxin-antikörper und anti-lymphotoxin ligand antikörper als therapeutische wirkstoffe zur behandlung von immunologischen krankheiten
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TR200504220T2 (tr) * 1998-12-17 2007-04-24 Biogen Idec Ma Inc. Aktif limfotoksin-beta reseptör imunoglobülin şimeAktif limfotoksin-beta reseptör imunoglobülin şimerik proteinlerinin yüksek düzey ifadesi ve saflaştrik proteinlerinin yüksek düzey ifadesi ve saflaştırılması için bir yöntem.ırılması için bir yöntem.
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HUP0302573A2 (hu) * 2000-10-13 2003-10-28 Biogen, Inc. Humanizált anti-LT-béta-R ellenanyagok
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WO2002083162A1 (en) * 2001-04-13 2002-10-24 University Of Chicago Use of a cd8+ t cell inhibitory agent in the presence of a cd4+ t cell inhibitory agent for inhibition of transplant rejection
US7265208B2 (en) 2001-05-01 2007-09-04 The Regents Of The University Of California Fusion molecules and treatment of IgE-mediated allergic diseases
WO2003011322A1 (en) * 2001-08-02 2003-02-13 Genset S.A. Agonists and antagonists of genoxin for use in the treatment of metabolic disorders
US7273707B2 (en) * 2002-02-08 2007-09-25 Wyeth Method of identifying a modulator of a LTβR complex signaling pathway
CA2491480A1 (en) * 2002-07-01 2004-01-08 Biogen, Inc. Humanized anti-lymphotoxin beta receptor antibodies
AU2003287431A1 (en) * 2002-10-31 2004-05-25 Biogen Idec Ma Inc. Treatment of immunological renal disorders by lymphotoxin pathway inhibitors
JP2006513225A (ja) * 2002-12-20 2006-04-20 バイオジェン・アイデック・エムエイ・インコーポレイテッド 化学療法剤と組み合わせたリンホトキシンβ受容体因子
CA2511013A1 (en) * 2002-12-20 2004-07-15 Biogen Idec Ma Inc. Multivalent lymphotoxin beta receptor agonists and therapeutic uses thereof
NZ544924A (en) * 2003-06-27 2009-03-31 Biogen Idec Inc Modified binding molecules comprising connecting peptides
EP1699486A4 (en) * 2003-12-08 2007-07-18 Centocor Inc ANTI-LYMPHOTOXIN HUMAN ALPHA ANTIBODIES, COMPOSITIONS, METHODS AND USES
CN1980957A (zh) * 2004-03-23 2007-06-13 比奥根艾迪克Ma公司 受体偶联剂及其治疗用途
JP2008509153A (ja) * 2004-08-03 2008-03-27 バイオレクシス ファーマシューティカル コーポレイション Glp−1を含むトランスフェリン融合タンパク質用いた併用療法
WO2006074399A2 (en) * 2005-01-05 2006-07-13 Biogen Idec Ma Inc. Multispecific binding molecules comprising connecting peptides
WO2006135660A2 (en) * 2005-06-10 2006-12-21 University Of Chicago Therapies involving lymphotoxin beta receptor
EP1942936A2 (en) * 2005-10-04 2008-07-16 The Johns Hopkins University Compositions and methods for treating inflammation
WO2007109733A2 (en) 2006-03-21 2007-09-27 The Johns Hopkins University Diagnostic and prognostic markers and treatment strategies for multiple sclerosis
JP5102833B2 (ja) * 2006-07-24 2012-12-19 バイオレクシス ファーマシューティカル コーポレーション エキセンディン融合タンパク質
WO2008063776A2 (en) 2006-10-12 2008-05-29 Genentech, Inc. Antibodies to lymphotoxin-alpha
NZ576424A (en) 2006-10-20 2012-09-28 Biogen Idec Inc Treatment of demyelinating disorders with soluble lymphotoxin-beta-receptor
US8338376B2 (en) * 2006-10-20 2012-12-25 Biogen Idec Ma Inc. Compositions comprising variant LT-B-R-IG fusion proteins
KR101581961B1 (ko) 2006-11-02 2016-01-04 악셀레론 파마 인코포레이티드 Alk1 수용체 및 리간드 길항제 및 그의 용도
US8440185B2 (en) 2006-12-26 2013-05-14 The Johns Hopkins University Compositions and methods for the treatment of immunologic disorders
EP2139509A2 (en) * 2007-03-15 2010-01-06 Biogen Idec MA, Inc. Treatment of autoimmune disorders
AU2008261869B2 (en) 2007-06-08 2014-12-18 Biogen Ma Inc. Biomarkers for predicting anti-TNF responsiveness or non-responsiveness
CA2748757A1 (en) * 2008-12-31 2010-07-08 Biogen Idec Ma Inc. Anti-lymphotoxin antibodies
KR20180033499A (ko) 2015-06-05 2018-04-03 아이바이오, 인크. 섬유증을 치료하는데 사용하기 위한 엔도스타틴 단편 및 변이체
US12448458B2 (en) * 2018-06-15 2025-10-21 Universität Bern Ligands to light or its receptor LTßR for use in haematologic malignancies
EP3969569A1 (en) 2019-05-14 2022-03-23 INSERM (Institut National de la Santé et de la Recherche Médicale) Regulatory t cells targeted by lymphotoxin alpha blocking agent and uses thereof
WO2023028451A2 (en) 2021-08-25 2023-03-02 Ibio, Inc. Anti-cd-25 antibody

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CA2491480A1 (en) 2002-07-01 2004-01-08 Biogen, Inc. Humanized anti-lymphotoxin beta receptor antibodies
CA2511013A1 (en) 2002-12-20 2004-07-15 Biogen Idec Ma Inc. Multivalent lymphotoxin beta receptor agonists and therapeutic uses thereof
JP2006513225A (ja) 2002-12-20 2006-04-20 バイオジェン・アイデック・エムエイ・インコーポレイテッド 化学療法剤と組み合わせたリンホトキシンβ受容体因子
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