JPH11510488A5 - - Google Patents

Info

Publication number
JPH11510488A5
JPH11510488A5 JP1997506919A JP50691997A JPH11510488A5 JP H11510488 A5 JPH11510488 A5 JP H11510488A5 JP 1997506919 A JP1997506919 A JP 1997506919A JP 50691997 A JP50691997 A JP 50691997A JP H11510488 A5 JPH11510488 A5 JP H11510488A5
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP1997506919A
Other languages
English (en)
Japanese (ja)
Other versions
JP4174563B2 (ja
JPH11510488A (ja
Filing date
Publication date
Priority claimed from US08/505,606 external-priority patent/US5925351A/en
Application filed filed Critical
Publication of JPH11510488A publication Critical patent/JPH11510488A/ja
Publication of JPH11510488A5 publication Critical patent/JPH11510488A5/ja
Application granted granted Critical
Publication of JP4174563B2 publication Critical patent/JP4174563B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

JP50691997A 1995-07-21 1996-07-19 免疫学的疾患の処置のための治療剤としての可溶性リンホトキシン−βレセプターならびに抗リンホトキシンレセプターおよびリガンド抗体 Expired - Fee Related JP4174563B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/505,606 1995-07-21
US08/505,606 US5925351A (en) 1995-07-21 1995-07-21 Soluble lymphotoxin-β receptors and anti-lymphotoxin receptor and ligand antibodies as therapeutic agents for the treatment of immunological disease
PCT/US1996/012010 WO1997003687A1 (en) 1995-07-21 1996-07-19 SOLUBLE LYMPHOTOXIN-β RECEPTORS AND ANTI-LYMPHOTOXIN RECEPTOR AND LIGAND ANTIBODIES, AS THERAPEUTIC AGENTS FOR THE TREATMENT OF IMMUNOLOGICAL DISEASE

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2007161925A Division JP2007254488A (ja) 1995-07-21 2007-06-19 免疫学的疾患の処置のための治療剤としての可溶性リンホトキシン−βレセプターならびに抗リンホトキシンレセプターおよびリガンド抗体

Publications (3)

Publication Number Publication Date
JPH11510488A JPH11510488A (ja) 1999-09-14
JPH11510488A5 true JPH11510488A5 (enExample) 2004-08-26
JP4174563B2 JP4174563B2 (ja) 2008-11-05

Family

ID=24011046

Family Applications (3)

Application Number Title Priority Date Filing Date
JP50691997A Expired - Fee Related JP4174563B2 (ja) 1995-07-21 1996-07-19 免疫学的疾患の処置のための治療剤としての可溶性リンホトキシン−βレセプターならびに抗リンホトキシンレセプターおよびリガンド抗体
JP2007161925A Withdrawn JP2007254488A (ja) 1995-07-21 2007-06-19 免疫学的疾患の処置のための治療剤としての可溶性リンホトキシン−βレセプターならびに抗リンホトキシンレセプターおよびリガンド抗体
JP2011209921A Withdrawn JP2012041350A (ja) 1995-07-21 2011-09-26 免疫学的疾患の処置のための治療剤としての可溶性リンホトキシン−βレセプターならびに抗リンホトキシンレセプターおよびリガンド抗体

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2007161925A Withdrawn JP2007254488A (ja) 1995-07-21 2007-06-19 免疫学的疾患の処置のための治療剤としての可溶性リンホトキシン−βレセプターならびに抗リンホトキシンレセプターおよびリガンド抗体
JP2011209921A Withdrawn JP2012041350A (ja) 1995-07-21 2011-09-26 免疫学的疾患の処置のための治療剤としての可溶性リンホトキシン−βレセプターならびに抗リンホトキシンレセプターおよびリガンド抗体

Country Status (28)

Country Link
US (6) US5925351A (enExample)
EP (2) EP0840616B1 (enExample)
JP (3) JP4174563B2 (enExample)
KR (2) KR100557258B1 (enExample)
CN (3) CN1607005A (enExample)
AT (1) ATE279205T1 (enExample)
AU (1) AU715407B2 (enExample)
BG (1) BG63330B1 (enExample)
BR (1) BR9609716A (enExample)
CA (1) CA2227477A1 (enExample)
CZ (1) CZ298277B6 (enExample)
DE (1) DE69633624T2 (enExample)
DK (1) DK0840616T3 (enExample)
EA (3) EA001200B1 (enExample)
EE (1) EE04419B1 (enExample)
ES (1) ES2225889T3 (enExample)
FI (1) FI980122L (enExample)
HU (1) HU227508B1 (enExample)
MX (1) MX9800624A (enExample)
NO (2) NO327163B1 (enExample)
NZ (2) NZ503818A (enExample)
PL (1) PL186911B1 (enExample)
PT (1) PT840616E (enExample)
RO (1) RO121799B1 (enExample)
SI (1) SI0840616T1 (enExample)
SK (1) SK286409B6 (enExample)
TR (1) TR199800091T1 (enExample)
WO (1) WO1997003687A1 (enExample)

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US7255854B1 (en) * 1996-10-25 2007-08-14 Biogen, Inc. Use of lymphotoxin-β receptor blocking agents for the treatment of antibody mediated immunological diseases
CA2269614A1 (en) * 1996-10-25 1998-04-30 Biogen, Inc. Soluble lymphotoxin-beta receptors, anti-lymphotoxin receptor antibodies, and anti-lymphotoxin ligand antibodies as therapeutic agents for the treatment of immunological diseases
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JP2001515360A (ja) * 1997-04-18 2001-09-18 バイオジェン,インコーポレイテッド ▲II▼型TGF−βレセプター/免疫グロブリン定常領域融合タンパク質
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TR200504220T2 (tr) 1998-12-17 2007-04-24 Biogen Idec Ma Inc. Aktif limfotoksin-beta reseptör imunoglobülin şimeAktif limfotoksin-beta reseptör imunoglobülin şimerik proteinlerinin yüksek düzey ifadesi ve saflaştrik proteinlerinin yüksek düzey ifadesi ve saflaştırılması için bir yöntem.ırılması için bir yöntem.
KR20020016852A (ko) * 1999-06-28 2002-03-06 스타르크, 카르크 종양 성장의 억제 방법
US6346247B1 (en) 1999-10-28 2002-02-12 Promega Corporation Prevention and treatment of autoimmune disease with luminally administered polyclonal antibodies
AU1174702A (en) * 2000-10-13 2002-04-22 Biogen Inc Humanized anti-lt-beta-r antibodies
DK1724284T3 (da) * 2000-12-07 2009-11-02 Lilly Co Eli GLP-1 fusionsproteiner
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US7265208B2 (en) 2001-05-01 2007-09-04 The Regents Of The University Of California Fusion molecules and treatment of IgE-mediated allergic diseases
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EP1578920A4 (en) * 2002-02-08 2007-11-21 Wyeth Corp COMPOSITION AND METHOD FOR MODULATING AN INFLAMMATORY REACTION
JP2005532051A (ja) * 2002-07-01 2005-10-27 バイオジェン, インコーポレイテッド ヒト化抗リンホトキシンβレセプター抗体
JP2006504775A (ja) * 2002-10-31 2006-02-09 バイオジェン・アイデック・エムエイ・インコーポレイテッド リンホトキシン経路インヒビターによる免疫学的腎障害の処置
EP1583503A4 (en) * 2002-12-20 2006-08-09 Biogen Idec Inc POLYVALENT LYMPHOTOXIN BETA RECEPTOR AGONISTS AND THERAPEUTIC USE THEREOF
CN1753692A (zh) * 2002-12-20 2006-03-29 比奥根艾迪克Ma公司 淋巴毒素β受体药剂与化疗剂的联合用药
JP5091476B2 (ja) * 2003-06-27 2012-12-05 バイオジェン・アイデック・エムエイ・インコーポレイテッド 均質な抗体溶液の生成のための疎水性相互作用クロマトグラフィーまたはヒンジ領域改変の使用
WO2005067477A2 (en) * 2003-12-08 2005-07-28 Centocor, Inc. Anti-human lymphotoxin alpha antibodies, compositions, methods and uses
EP1756162A1 (en) * 2004-03-23 2007-02-28 Biogen Idec MA Inc. Receptor coupling agents and therapeutic uses thereof
AU2005271403A1 (en) * 2004-08-03 2006-02-16 Biorexis Pharmaceutical Corporation Combination therapy using transferrin fusion proteins comprising GLP-1
WO2006074399A2 (en) * 2005-01-05 2006-07-13 Biogen Idec Ma Inc. Multispecific binding molecules comprising connecting peptides
WO2006135660A2 (en) * 2005-06-10 2006-12-21 University Of Chicago Therapies involving lymphotoxin beta receptor
WO2007041694A2 (en) * 2005-10-04 2007-04-12 The Johns Hopkins University Compositions and methods for treating inflammation
WO2007109733A2 (en) 2006-03-21 2007-09-27 The Johns Hopkins University Diagnostic and prognostic markers and treatment strategies for multiple sclerosis
ES2371495T3 (es) 2006-07-24 2012-01-03 Biorexis Pharmaceutical Corporation Proteínas de fusión de exendina.
JP5298021B2 (ja) * 2006-10-12 2013-09-25 ジェネンテック, インコーポレイテッド リンホトキシン−αに対する抗体
WO2008112325A2 (en) * 2007-03-15 2008-09-18 Biogen Idec Ma Inc. Treatment of autoimmune disorders
US8338376B2 (en) * 2006-10-20 2012-12-25 Biogen Idec Ma Inc. Compositions comprising variant LT-B-R-IG fusion proteins
KR20090071652A (ko) * 2006-10-20 2009-07-01 바이오겐 아이덱 엠에이 인코포레이티드 가용성 림프독소-베타-수용체를 이용한 탈수초성 장애의 치료
ES2612755T3 (es) 2006-11-02 2017-05-18 Acceleron Pharma, Inc. Antagonistas de receptor y ligando de ALK1 y usos de los mismos
US8440185B2 (en) 2006-12-26 2013-05-14 The Johns Hopkins University Compositions and methods for the treatment of immunologic disorders
CN103710458A (zh) 2007-06-08 2014-04-09 比奥根艾迪克Ma公司 预测抗tnf响应性或无响应性的生物标志物
AU2009334498A1 (en) 2008-12-31 2011-07-21 Biogen Idec Ma Inc. Anti-lymphotoxin antibodies
CA2988299C (en) 2015-06-05 2023-10-31 Ibio, Inc. Endostatin fragments and variants for use in treating fibrosis
EP3807401A1 (en) * 2018-06-15 2021-04-21 Universität Bern LIGANDS TO LIGHT OR ITS RECEPTOR LTßR FOR USE IN HAEMATOLOGIC MALIGNANCIES
JP2022533591A (ja) 2019-05-14 2022-07-25 アンスティチュ ナショナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシュ メディカル リンホトキシンアルファ遮断剤によりターゲットされた制御性t細胞及びその使用
KR20240049361A (ko) 2021-08-25 2024-04-16 아이바이오, 인크. 항-cd25 항체

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AU1174702A (en) * 2000-10-13 2002-04-22 Biogen Inc Humanized anti-lt-beta-r antibodies
JP2005532051A (ja) * 2002-07-01 2005-10-27 バイオジェン, インコーポレイテッド ヒト化抗リンホトキシンβレセプター抗体
CN1753692A (zh) * 2002-12-20 2006-03-29 比奥根艾迪克Ma公司 淋巴毒素β受体药剂与化疗剂的联合用药
EP1583503A4 (en) * 2002-12-20 2006-08-09 Biogen Idec Inc POLYVALENT LYMPHOTOXIN BETA RECEPTOR AGONISTS AND THERAPEUTIC USE THEREOF
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