JPH11510488A5 - - Google Patents

Info

Publication number
JPH11510488A5
JPH11510488A5 JP1997506919A JP50691997A JPH11510488A5 JP H11510488 A5 JPH11510488 A5 JP H11510488A5 JP 1997506919 A JP1997506919 A JP 1997506919A JP 50691997 A JP50691997 A JP 50691997A JP H11510488 A5 JPH11510488 A5 JP H11510488A5
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP1997506919A
Other languages
English (en)
Japanese (ja)
Other versions
JP4174563B2 (ja
JPH11510488A (ja
Filing date
Publication date
Priority claimed from US08/505,606 external-priority patent/US5925351A/en
Application filed filed Critical
Publication of JPH11510488A publication Critical patent/JPH11510488A/ja
Publication of JPH11510488A5 publication Critical patent/JPH11510488A5/ja
Application granted granted Critical
Publication of JP4174563B2 publication Critical patent/JP4174563B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

JP50691997A 1995-07-21 1996-07-19 免疫学的疾患の処置のための治療剤としての可溶性リンホトキシン−βレセプターならびに抗リンホトキシンレセプターおよびリガンド抗体 Expired - Fee Related JP4174563B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/505,606 US5925351A (en) 1995-07-21 1995-07-21 Soluble lymphotoxin-β receptors and anti-lymphotoxin receptor and ligand antibodies as therapeutic agents for the treatment of immunological disease
US08/505,606 1995-07-21
PCT/US1996/012010 WO1997003687A1 (en) 1995-07-21 1996-07-19 SOLUBLE LYMPHOTOXIN-β RECEPTORS AND ANTI-LYMPHOTOXIN RECEPTOR AND LIGAND ANTIBODIES, AS THERAPEUTIC AGENTS FOR THE TREATMENT OF IMMUNOLOGICAL DISEASE

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2007161925A Division JP2007254488A (ja) 1995-07-21 2007-06-19 免疫学的疾患の処置のための治療剤としての可溶性リンホトキシン−βレセプターならびに抗リンホトキシンレセプターおよびリガンド抗体

Publications (3)

Publication Number Publication Date
JPH11510488A JPH11510488A (ja) 1999-09-14
JPH11510488A5 true JPH11510488A5 (enExample) 2004-08-26
JP4174563B2 JP4174563B2 (ja) 2008-11-05

Family

ID=24011046

Family Applications (3)

Application Number Title Priority Date Filing Date
JP50691997A Expired - Fee Related JP4174563B2 (ja) 1995-07-21 1996-07-19 免疫学的疾患の処置のための治療剤としての可溶性リンホトキシン−βレセプターならびに抗リンホトキシンレセプターおよびリガンド抗体
JP2007161925A Withdrawn JP2007254488A (ja) 1995-07-21 2007-06-19 免疫学的疾患の処置のための治療剤としての可溶性リンホトキシン−βレセプターならびに抗リンホトキシンレセプターおよびリガンド抗体
JP2011209921A Withdrawn JP2012041350A (ja) 1995-07-21 2011-09-26 免疫学的疾患の処置のための治療剤としての可溶性リンホトキシン−βレセプターならびに抗リンホトキシンレセプターおよびリガンド抗体

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2007161925A Withdrawn JP2007254488A (ja) 1995-07-21 2007-06-19 免疫学的疾患の処置のための治療剤としての可溶性リンホトキシン−βレセプターならびに抗リンホトキシンレセプターおよびリガンド抗体
JP2011209921A Withdrawn JP2012041350A (ja) 1995-07-21 2011-09-26 免疫学的疾患の処置のための治療剤としての可溶性リンホトキシン−βレセプターならびに抗リンホトキシンレセプターおよびリガンド抗体

Country Status (28)

Country Link
US (6) US5925351A (enExample)
EP (2) EP0840616B1 (enExample)
JP (3) JP4174563B2 (enExample)
KR (2) KR100557258B1 (enExample)
CN (3) CN1607005A (enExample)
AT (1) ATE279205T1 (enExample)
AU (1) AU715407B2 (enExample)
BG (1) BG63330B1 (enExample)
BR (1) BR9609716A (enExample)
CA (1) CA2227477A1 (enExample)
CZ (1) CZ298277B6 (enExample)
DE (1) DE69633624T2 (enExample)
DK (1) DK0840616T3 (enExample)
EA (3) EA005734B1 (enExample)
EE (1) EE04419B1 (enExample)
ES (1) ES2225889T3 (enExample)
FI (1) FI980122A7 (enExample)
HU (1) HU227508B1 (enExample)
MX (1) MX9800624A (enExample)
NO (2) NO327163B1 (enExample)
NZ (2) NZ503818A (enExample)
PL (1) PL186911B1 (enExample)
PT (1) PT840616E (enExample)
RO (1) RO121799B1 (enExample)
SI (1) SI0840616T1 (enExample)
SK (1) SK286409B6 (enExample)
TR (1) TR199800091T1 (enExample)
WO (1) WO1997003687A1 (enExample)

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IL129527A (en) * 1996-10-25 2006-12-10 Biogen Idec Inc Pharmaceutical preparations containing soluble lymphoxine-beta receptors
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US7060667B1 (en) * 1998-01-30 2006-06-13 Biogen Idec Ma, Inc. Treatment of follicular lymphomas using inhibitors of the LT pathway
EA003862B1 (ru) * 1998-01-30 2003-10-30 Байоджен, Инк. Способ прекращения или замедления развития фолликулярной лимфомы и композиции для его осуществления
HUP0103773A3 (en) * 1998-10-09 2003-10-28 Biogen Idec Ma Inc Cambridge Reversal of viral-induced systemic schock and respiratory distress by blockade of the lymphotoxin beta pathway
TR200504220T2 (tr) 1998-12-17 2007-04-24 Biogen Idec Ma Inc. Aktif limfotoksin-beta reseptör imunoglobülin şimeAktif limfotoksin-beta reseptör imunoglobülin şimerik proteinlerinin yüksek düzey ifadesi ve saflaştrik proteinlerinin yüksek düzey ifadesi ve saflaştırılması için bir yöntem.ırılması için bir yöntem.
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US6346247B1 (en) 1999-10-28 2002-02-12 Promega Corporation Prevention and treatment of autoimmune disease with luminally administered polyclonal antibodies
AR035352A1 (es) * 2000-10-13 2004-05-12 Biogen Inc Anticuerpos anti-lt-beta-r humanizados
DK1355942T3 (da) * 2000-12-07 2008-11-17 Lilly Co Eli GLP-1-fusionsproteiner
WO2002083162A1 (en) * 2001-04-13 2002-10-24 University Of Chicago Use of a cd8+ t cell inhibitory agent in the presence of a cd4+ t cell inhibitory agent for inhibition of transplant rejection
US7265208B2 (en) * 2001-05-01 2007-09-04 The Regents Of The University Of California Fusion molecules and treatment of IgE-mediated allergic diseases
WO2003011322A1 (en) * 2001-08-02 2003-02-13 Genset S.A. Agonists and antagonists of genoxin for use in the treatment of metabolic disorders
WO2003066834A2 (en) * 2002-02-08 2003-08-14 Wyeth Composition and method for modulating an inflammatory response
CN1678625A (zh) * 2002-07-01 2005-10-05 比奥根艾迪克Ma公司 人源化抗淋巴毒素β受体的抗体
AU2003287431A1 (en) * 2002-10-31 2004-05-25 Biogen Idec Ma Inc. Treatment of immunological renal disorders by lymphotoxin pathway inhibitors
AU2003299984A1 (en) * 2002-12-20 2004-07-22 Biogen Idec Ma Inc. Multivalent lymphotoxin beta receptor agonists and therapeutic uses thereof
RS20050481A (sr) * 2002-12-20 2007-08-03 Biogen Idec Ma Inc., Agensi limfotoksin beta receptora u kombinaciji sa hemoterapeutskim agensima
WO2005000898A2 (en) * 2003-06-27 2005-01-06 Biogen Idec Ma Inc. Use of hydrophobic-interaction-chromatography or hinge-region modifications for the production of homogeneous antibody-solutions
EP1699486A4 (en) * 2003-12-08 2007-07-18 Centocor Inc ANTI-LYMPHOTOXIN HUMAN ALPHA ANTIBODIES, COMPOSITIONS, METHODS AND USES
EP1756162A1 (en) * 2004-03-23 2007-02-28 Biogen Idec MA Inc. Receptor coupling agents and therapeutic uses thereof
ZA200701484B (en) * 2004-08-03 2008-07-30 Biorexis Pharmaceutical Corp Combination therapy using transferrin fusion proteins comprising GLP-1
WO2006074399A2 (en) * 2005-01-05 2006-07-13 Biogen Idec Ma Inc. Multispecific binding molecules comprising connecting peptides
WO2006135660A2 (en) * 2005-06-10 2006-12-21 University Of Chicago Therapies involving lymphotoxin beta receptor
WO2007041694A2 (en) * 2005-10-04 2007-04-12 The Johns Hopkins University Compositions and methods for treating inflammation
WO2007109733A2 (en) 2006-03-21 2007-09-27 The Johns Hopkins University Diagnostic and prognostic markers and treatment strategies for multiple sclerosis
ES2371495T3 (es) * 2006-07-24 2012-01-03 Biorexis Pharmaceutical Corporation Proteínas de fusión de exendina.
JP5298021B2 (ja) 2006-10-12 2013-09-25 ジェネンテック， インコーポレイテッド リンホトキシン−αに対する抗体
US8338376B2 (en) * 2006-10-20 2012-12-25 Biogen Idec Ma Inc. Compositions comprising variant LT-B-R-IG fusion proteins
WO2008049053A2 (en) * 2006-10-20 2008-04-24 Biogen Idec Ma Inc. Treatment of demyelinating disorders with soluble lymphotoxin-beta-receptor
WO2008057461A2 (en) 2006-11-02 2008-05-15 Acceleron Pharma, Inc. Alk1 receptor and ligand antagonists and uses thereof
US8440185B2 (en) 2006-12-26 2013-05-14 The Johns Hopkins University Compositions and methods for the treatment of immunologic disorders
EP2139509A2 (en) * 2007-03-15 2010-01-06 Biogen Idec MA, Inc. Treatment of autoimmune disorders
CA2690898A1 (en) 2007-06-08 2008-12-18 Biogen Idec Ma Inc. Biomarkers for predicting anti-tnf responsiveness or non-responsiveness
JP2012514458A (ja) * 2008-12-31 2012-06-28 バイオジェン・アイデック・エムエイ・インコーポレイテッド 抗リンホトキシン抗体
JP6952685B2 (ja) 2015-06-05 2021-10-20 アイバイオ・インコーポレイテッドＩｂｉｏ， Ｉｎｃ． 線維症の治療において使用するためのエンドスタチン断片およびバリアント
EP3807401A1 (en) * 2018-06-15 2021-04-21 Universität Bern LIGANDS TO LIGHT OR ITS RECEPTOR LTßR FOR USE IN HAEMATOLOGIC MALIGNANCIES
US12146160B2 (en) 2019-05-14 2024-11-19 Institut National De La Sante Et De La Recherche Medicale (Inserm) Regulatory T cells targeted by lymphotoxin alpha blocking agent and uses thereof
WO2023028451A2 (en) 2021-08-25 2023-03-02 Ibio, Inc. Anti-cd-25 antibody

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TR200504220T2 (tr) * 1998-12-17 2007-04-24 Biogen Idec Ma Inc. Aktif limfotoksin-beta reseptör imunoglobülin şimeAktif limfotoksin-beta reseptör imunoglobülin şimerik proteinlerinin yüksek düzey ifadesi ve saflaştrik proteinlerinin yüksek düzey ifadesi ve saflaştırılması için bir yöntem.ırılması için bir yöntem.
AR035352A1 (es) * 2000-10-13 2004-05-12 Biogen Inc Anticuerpos anti-lt-beta-r humanizados
CN1678625A (zh) * 2002-07-01 2005-10-05 比奥根艾迪克Ma公司 人源化抗淋巴毒素β受体的抗体
AU2003299984A1 (en) * 2002-12-20 2004-07-22 Biogen Idec Ma Inc. Multivalent lymphotoxin beta receptor agonists and therapeutic uses thereof
RS20050481A (sr) * 2002-12-20 2007-08-03 Biogen Idec Ma Inc., Agensi limfotoksin beta receptora u kombinaciji sa hemoterapeutskim agensima
EP1756162A1 (en) * 2004-03-23 2007-02-28 Biogen Idec MA Inc. Receptor coupling agents and therapeutic uses thereof
WO2007146414A2 (en) 2006-06-15 2007-12-21 Biogen Idec Ma Inc. Combination therapy employing lymphotoxin beta receptor binding molecules in combination with second agents

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