JPH11507017A5 - - Google Patents
Info
- Publication number
- JPH11507017A5 JPH11507017A5 JP1996534120A JP53412096A JPH11507017A5 JP H11507017 A5 JPH11507017 A5 JP H11507017A5 JP 1996534120 A JP1996534120 A JP 1996534120A JP 53412096 A JP53412096 A JP 53412096A JP H11507017 A5 JPH11507017 A5 JP H11507017A5
- Authority
- JP
- Japan
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US43670895A | 1995-05-08 | 1995-05-08 | |
| US08/436,708 | 1995-05-08 | ||
| PCT/US1996/006119 WO1996035678A1 (en) | 1995-05-08 | 1996-05-03 | Alpha-substituted pyrimidine-thioalkyl and alkylether compounds as inhibitors of viral reverse transcriptase |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPH11507017A JPH11507017A (ja) | 1999-06-22 |
| JPH11507017A5 true JPH11507017A5 (https=) | 2004-07-08 |
Family
ID=23733510
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP8534120A Withdrawn JPH11507017A (ja) | 1995-05-08 | 1996-05-03 | ウイルス逆転写酵素の阻害剤としてのα−置換のピリミジン−チオアルキルおよびアルキルエーテル化合物 |
Country Status (26)
| Country | Link |
|---|---|
| US (1) | US6043248A (https=) |
| EP (2) | EP0824524B1 (https=) |
| JP (1) | JPH11507017A (https=) |
| KR (1) | KR100445498B1 (https=) |
| CN (2) | CN1535958A (https=) |
| AT (1) | ATE275550T1 (https=) |
| AU (1) | AU712404B2 (https=) |
| BR (1) | BR9608265A (https=) |
| CA (1) | CA2216099C (https=) |
| CZ (1) | CZ293135B6 (https=) |
| DE (1) | DE69633332T2 (https=) |
| ES (1) | ES2227586T3 (https=) |
| GE (1) | GEP20002297B (https=) |
| HU (1) | HUP9801995A3 (https=) |
| IL (1) | IL118075A0 (https=) |
| MX (1) | MX9708582A (https=) |
| NO (1) | NO310287B1 (https=) |
| NZ (1) | NZ307089A (https=) |
| PL (1) | PL323240A1 (https=) |
| PT (1) | PT824524E (https=) |
| RU (1) | RU2167155C2 (https=) |
| SK (1) | SK150297A3 (https=) |
| TW (1) | TW450962B (https=) |
| UA (1) | UA56992C2 (https=) |
| WO (1) | WO1996035678A1 (https=) |
| ZA (1) | ZA963281B (https=) |
Families Citing this family (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1034167A1 (en) * | 1997-09-25 | 2000-09-13 | PHARMACIA & UPJOHN COMPANY | Alpha-alkylthio substituted pyrimidine ethers and thioethers as viral reverse transcriptase inhibitors |
| US6111111A (en) | 1997-10-23 | 2000-08-29 | Kuraray Co., Ltd. | Intermediates for producing pyridine derivatives |
| US7358254B2 (en) | 2001-07-13 | 2008-04-15 | Bristol-Myers Squibb Company | Method for treating atherosclerosis employing an aP2 inhibitor and combination |
| TR200100773T2 (tr) | 1998-09-17 | 2001-07-23 | Bristol-Myers Squibb Company | Bir aP2 önleyicisinin ve kombinasyonunun kullanıldığı diyabet tedavi yöntemi |
| WO2001000214A1 (en) | 1999-06-30 | 2001-01-04 | Merck & Co., Inc. | Src kinase inhibitor compounds |
| JP2003503351A (ja) | 1999-06-30 | 2003-01-28 | メルク エンド カムパニー インコーポレーテッド | Ｓｒｃキナーゼ阻害化合物 |
| AU5636900A (en) | 1999-06-30 | 2001-01-31 | Merck & Co., Inc. | Src kinase inhibitor compounds |
| US7138404B2 (en) * | 2001-05-23 | 2006-11-21 | Hoffmann-La Roche Inc. | 4-aminopyrimidine derivatives |
| MX2007006635A (es) * | 2004-12-03 | 2007-06-19 | Merck & Co Inc | Formulacion farmaceutica de inhibidores dela carboxamida vih integrasa que contienen una composicion que controla la velocidad de liberacion. |
| US20080214588A1 (en) * | 2005-03-04 | 2008-09-04 | Herman Augustinus De Kock | Hiv Inhibiting 2-(4-Cyanophenyl)-6-Hydroxylaminopyrimidines |
| US7923056B2 (en) | 2007-06-01 | 2011-04-12 | Illinois Tool Works Inc. | Method and apparatus for dispensing material on a substrate |
| AR076601A1 (es) | 2009-05-21 | 2011-06-22 | Chlorion Pharma Inc | Pirimidinas como agentes terapeuticos |
| CN101638391B (zh) * | 2009-08-21 | 2011-04-27 | 山东大学 | 2-[(取代苯氨基)羰基甲硫基]-6-(2,6-二氯苄基)-3h-嘧啶-4-酮类衍生物及其制备方法与应用 |
| US9226970B2 (en) | 2010-02-22 | 2016-01-05 | Nektar Therapeutics | Oligomer modified diaromatic substituted compounds |
| EP2550362B1 (en) | 2010-03-25 | 2017-01-04 | Oregon Health&Science University | Cmv glycoproteins and recombinant vectors |
| AP2013006706A0 (en) * | 2010-07-02 | 2013-02-28 | Gilead Sciences Inc | Napht-2-ylacetic acid derivatives to treat AIDS |
| CA2832109C (en) | 2011-06-10 | 2021-07-06 | Oregon Health & Science University | Cmv glycoproteins and recombinant vectors |
| EP2568289A3 (en) | 2011-09-12 | 2013-04-03 | International AIDS Vaccine Initiative | Immunoselection of recombinant vesicular stomatitis virus expressing hiv-1 proteins by broadly neutralizing antibodies |
| US9402894B2 (en) | 2011-10-27 | 2016-08-02 | International Aids Vaccine Initiative | Viral particles derived from an enveloped virus |
| EP2679596B1 (en) | 2012-06-27 | 2017-04-12 | International Aids Vaccine Initiative | HIV-1 env glycoprotein variant |
| KR101360587B1 (ko) * | 2012-11-01 | 2014-03-10 | 현대자동차주식회사 | 스마트 도어 언록 시스템 |
| EP2848937A1 (en) | 2013-09-05 | 2015-03-18 | International Aids Vaccine Initiative | Methods of identifying novel HIV-1 immunogens |
| US10058604B2 (en) | 2013-10-07 | 2018-08-28 | International Aids Vaccine Initiative | Soluble HIV-1 envelope glycoprotein trimers |
| EP3069730A3 (en) | 2015-03-20 | 2017-03-15 | International Aids Vaccine Initiative | Soluble hiv-1 envelope glycoprotein trimers |
| EP3072901A1 (en) | 2015-03-23 | 2016-09-28 | International Aids Vaccine Initiative | Soluble hiv-1 envelope glycoprotein trimers |
| MY197231A (en) | 2015-07-22 | 2023-06-06 | Enanta Pharm Inc | Benzodiazepine derivatives as rsv inhibitors |
| GB201807898D0 (en) * | 2018-05-15 | 2018-06-27 | Kancera Ab | New processes and products with increased chiral purity |
| US11505558B1 (en) | 2019-10-04 | 2022-11-22 | Enanta Pharmaceuticals, Inc. | Antiviral heterocyclic compounds |
| AU2020357452B2 (en) * | 2019-10-04 | 2026-01-29 | Enanta Pharmaceuticals, Inc | Antiviral heterocyclic compounds |
| US20230112484A1 (en) * | 2020-01-20 | 2023-04-13 | Agrematch Ltd. | Compositions for crop protection |
| UY39892A (es) | 2021-08-10 | 2023-03-31 | Novartis Pharma Ag | Compuestos y composiciones para tratar afecciones asociadas con la actividad de STING |
| CN114057707A (zh) * | 2021-11-24 | 2022-02-18 | 上海应用技术大学 | 一种n-4-吲哚基-2-呋喃甲酰胺化合物的制备方法 |
| EP4463441A1 (en) * | 2022-01-12 | 2024-11-20 | IFM Due, Inc. | Compounds and compositions for treating conditions associated with sting activity |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2295560A (en) * | 1941-06-18 | 1942-09-15 | Gen Electric | Pyrimidine derivatives |
| GB744867A (en) * | 1952-10-29 | 1956-02-15 | American Cyanamid Co | Improvements relating to 2-substituted-mercapto-4-amino-6-disubstituted-aminopyrimidines and acid addition salts thereof |
| US3940394A (en) * | 1972-03-31 | 1976-02-24 | Santilli Arthur A | 2-pyrimidinylthio)alkanoic acids, esters, amides and hydrazides |
| US3940240A (en) * | 1974-07-11 | 1976-02-24 | Ina Seito Co., Ltd. | Baking method and kiln for tile |
| DE3369514D1 (en) * | 1983-05-05 | 1987-03-05 | Heumann Ludwig & Co Gmbh | Pyrimidinethioalkyl pyridine derivatives, process for their preparation and medicines containing these compounds |
| US4724232A (en) * | 1985-03-16 | 1988-02-09 | Burroughs Wellcome Co. | Treatment of human viral infections |
| JPS62209062A (ja) * | 1986-03-10 | 1987-09-14 | Yamanouchi Pharmaceut Co Ltd | ２−ピリジルメチルチオ−または２−ピリジルメチルスルフイニル−置換縮合環化合物 |
| JPH07107056B2 (ja) * | 1987-01-30 | 1995-11-15 | 日清製粉株式会社 | ４（３ｈ）−キナゾリノン誘導体、その製造方法およびそれを有効成分とする抗潰瘍剤 |
| WO1989011279A1 (en) * | 1988-05-16 | 1989-11-30 | Georgia State University Foundation, Inc. | Nucleic acid interacting unfused heteropolycyclic compounds |
| HU203736B (en) * | 1989-04-06 | 1991-09-30 | Gyogyszerkutato Intezet | Process for producing new thiouracil-derivatives and pharmaceutical compositions containing them |
| HK1002235A1 (en) * | 1989-12-28 | 1998-08-07 | Pharmacia & Upjohn Company | Diaromatic substituted anti-aids compounds |
| US5668136A (en) * | 1990-09-25 | 1997-09-16 | Eisai Co., Ltd. | Trisubstituted benzene derivatives, composition and methods of treatment |
| DE69217224T2 (de) * | 1991-07-03 | 1997-06-05 | Pharmacia & Upjohn Co., Kalamazoo, Mich. | Substituierte indole als anti-aids pharmaceutische zubereitungen |
| GB2266716A (en) * | 1992-05-05 | 1993-11-10 | Merck & Co Inc | Inhibitors of HIV reverse transcriptase |
| JP3077046B2 (ja) * | 1992-08-31 | 2000-08-14 | 久光製薬株式会社 | 新規なキナゾリン誘導体 |
| EP0720607A1 (en) * | 1993-09-17 | 1996-07-10 | PHARMACIA & UPJOHN COMPANY | Substituted tetronic acids useful for treating hiv and other retroviruses |
| JPH09505050A (ja) * | 1993-11-12 | 1997-05-20 | ジ・アップジョン・カンパニー | ピリミジン−チオアルキルおよびアルキルエーテル化合物 |
| WO1995029897A1 (en) * | 1994-04-29 | 1995-11-09 | G.D. Searle & Co. | METHOD OF USING (H+/K+) ATPase INHIBITORS AS ANTIVIRAL AGENTS |
| RU2149872C1 (ru) * | 1994-07-20 | 2000-05-27 | Бык Гульден Ломберг Хемише Фабрик Гмбх | Пиридилтиосоединения для борьбы с бактериями helicobacter |
-
1996
- 1996-03-05 UA UA97125800A patent/UA56992C2/uk unknown
- 1996-04-24 ZA ZA9603281A patent/ZA963281B/xx unknown
- 1996-04-29 IL IL11807596A patent/IL118075A0/xx unknown
- 1996-05-03 AU AU56353/96A patent/AU712404B2/en not_active Ceased
- 1996-05-03 PL PL96323240A patent/PL323240A1/xx unknown
- 1996-05-03 EP EP96913306A patent/EP0824524B1/en not_active Expired - Lifetime
- 1996-05-03 CA CA002216099A patent/CA2216099C/en not_active Expired - Fee Related
- 1996-05-03 MX MX9708582A patent/MX9708582A/es not_active IP Right Cessation
- 1996-05-03 JP JP8534120A patent/JPH11507017A/ja not_active Withdrawn
- 1996-05-03 US US08/945,153 patent/US6043248A/en not_active Expired - Fee Related
- 1996-05-03 NZ NZ307089A patent/NZ307089A/xx unknown
- 1996-05-03 BR BR9608265A patent/BR9608265A/pt not_active Application Discontinuation
- 1996-05-03 CN CNA200410032589XA patent/CN1535958A/zh active Pending
- 1996-05-03 GE GEAP19964013A patent/GEP20002297B/en unknown
- 1996-05-03 RU RU97120116/04A patent/RU2167155C2/ru not_active IP Right Cessation
- 1996-05-03 WO PCT/US1996/006119 patent/WO1996035678A1/en not_active Ceased
- 1996-05-03 EP EP04010159A patent/EP1449835A3/en not_active Withdrawn
- 1996-05-03 DE DE69633332T patent/DE69633332T2/de not_active Expired - Fee Related
- 1996-05-03 CZ CZ19973491A patent/CZ293135B6/cs not_active IP Right Cessation
- 1996-05-03 SK SK1502-97A patent/SK150297A3/sk unknown
- 1996-05-03 HU HU9801995A patent/HUP9801995A3/hu unknown
- 1996-05-03 PT PT96913306T patent/PT824524E/pt unknown
- 1996-05-03 KR KR1019970707927A patent/KR100445498B1/ko not_active Expired - Fee Related
- 1996-05-03 ES ES96913306T patent/ES2227586T3/es not_active Expired - Lifetime
- 1996-05-03 AT AT96913306T patent/ATE275550T1/de not_active IP Right Cessation
- 1996-05-03 CN CNB961937912A patent/CN1152022C/zh not_active Expired - Fee Related
- 1996-05-07 TW TW085105432A patent/TW450962B/zh not_active IP Right Cessation
-
1997
- 1997-11-07 NO NO19975129A patent/NO310287B1/no unknown