JPH11506834A - オキシメータ用の調節可能な波長を有する光源 - Google Patents
オキシメータ用の調節可能な波長を有する光源Info
- Publication number
- JPH11506834A JPH11506834A JP9501166A JP50116697A JPH11506834A JP H11506834 A JPH11506834 A JP H11506834A JP 9501166 A JP9501166 A JP 9501166A JP 50116697 A JP50116697 A JP 50116697A JP H11506834 A JPH11506834 A JP H11506834A
- Authority
- JP
- Japan
- Prior art keywords
- wavelength
- light
- light emitting
- emitting diode
- led
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
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- 210000004369 blood Anatomy 0.000 claims description 34
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- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 claims description 31
- 229910052760 oxygen Inorganic materials 0.000 claims description 31
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- PNDPGZBMCMUPRI-UHFFFAOYSA-N iodine Chemical compound II PNDPGZBMCMUPRI-UHFFFAOYSA-N 0.000 description 1
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Classifications
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- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
- A61B5/1495—Calibrating or testing of in-vivo probes
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- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
- A61B5/0205—Simultaneously evaluating both cardiovascular conditions and different types of body conditions, e.g. heart and respiratory condition
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- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
- A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
- A61B5/14551—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters for measuring blood gases
- A61B5/14552—Details of sensors specially adapted therefor
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- A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
- A61B5/6801—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
- A61B5/6813—Specially adapted to be attached to a specific body part
- A61B5/6825—Hand
- A61B5/6826—Finger
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- A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
- A61B5/6801—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
- A61B5/683—Means for maintaining contact with the body
- A61B5/6838—Clamps or clips
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- G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
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- G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
- G01J3/02—Details
- G01J3/0205—Optical elements not provided otherwise, e.g. optical manifolds, diffusers, windows
- G01J3/0254—Spectrometers, other than colorimeters, making use of an integrating sphere
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- G—PHYSICS
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- G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
- G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
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- G01J3/027—Control of working procedures of a spectrometer; Failure detection; Bandwidth calculation
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- G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
- G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
- G01J3/02—Details
- G01J3/0275—Details making use of sensor-related data, e.g. for identification of sensor parts or optical elements
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
- G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
- G01J3/02—Details
- G01J3/0291—Housings; Spectrometer accessories; Spatial arrangement of elements, e.g. folded path arrangements
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
- G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
- G01J3/02—Details
- G01J3/10—Arrangements of light sources specially adapted for spectrometry or colorimetry
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- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
- G01N21/255—Details, e.g. use of specially adapted sources, lighting or optical systems
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- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
- G01N21/27—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands using photo-electric detection ; circuits for computing concentration
- G01N21/274—Calibration, base line adjustment, drift correction
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- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
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- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
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- G—PHYSICS
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- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
- G01N21/31—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
- G01N21/314—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry with comparison of measurements at specific and non-specific wavelengths
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- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
- G01N21/31—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
- G01N21/39—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using tunable lasers
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61B2562/00—Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
- A61B2562/08—Sensors provided with means for identification, e.g. barcodes or memory chips
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
- A61B5/024—Detecting, measuring or recording pulse rate or heart rate
- A61B5/02416—Detecting, measuring or recording pulse rate or heart rate using photoplethysmograph signals, e.g. generated by infrared radiation
- A61B5/02427—Details of sensor
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- G01—MEASURING; TESTING
- G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
- G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
- G01J3/28—Investigating the spectrum
- G01J2003/2866—Markers; Calibrating of scan
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- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
- G01N21/31—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
- G01N21/314—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry with comparison of measurements at specific and non-specific wavelengths
- G01N2021/3144—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry with comparison of measurements at specific and non-specific wavelengths for oxymetry
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- G01N2201/06—Illumination; Optics
- G01N2201/062—LED's
- G01N2201/0627—Use of several LED's for spectral resolution
Landscapes
- Physics & Mathematics (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Physics & Mathematics (AREA)
- General Health & Medical Sciences (AREA)
- Pathology (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Analytical Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Surgery (AREA)
- Medical Informatics (AREA)
- Heart & Thoracic Surgery (AREA)
- Biomedical Technology (AREA)
- Biophysics (AREA)
- Optics & Photonics (AREA)
- Cardiology (AREA)
- Physiology (AREA)
- Toxicology (AREA)
- Mathematical Physics (AREA)
- Theoretical Computer Science (AREA)
- Pulmonology (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
- Electrotherapy Devices (AREA)
- Electrochromic Elements, Electrophoresis, Or Variable Reflection Or Absorption Elements (AREA)
- Led Devices (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
- Holo Graphy (AREA)
- Control Of Indicators Other Than Cathode Ray Tubes (AREA)
- Lasers (AREA)
- Non-Silver Salt Photosensitive Materials And Non-Silver Salt Photography (AREA)
Abstract
Description
Claims (1)
- 【特許請求の範囲】 1.事前選択された電源電流を提供するように構成された電流源と; 前記電流源に結合された発光ダイオードであり、前記発光ダイオードが、事前 選択された同調パラメータのシフトに連れて波長がシフトするタイプである発光 ダイオードと; 前記発光ダイオードと並列に接続される同調素子であり、前記同調素子の値が インピーダンス値を持ち、前記事前選択された電源電流の第2の部分が前記発光 ダイオードを通過するように前記事前選択された電源電流の少なくとも第1の部 分を引き込むように前記同調素子が選択されており、前記事前選択された電源電 流の前記第2の部分が、前記発光ダイオードをして事前選択された波長を持つ光 エネルギを発生せしめるように選択されている同調素子と; を有することを特徴とする事前選択された波長で光エネルギを伝達する同調光伝 達ネットワーク。 2.前記同調素子が抵抗器を有することを特徴とする請求の範囲第1項記載の同調 光伝達ネットワーク。 3.前記同調パラメータが駆動電流のある範囲内の駆動電流であることを特徴とす る請求の範囲第1項記載の同調光伝達ネットワーク。 4.前記同調パラメータが駆動電圧のある範囲内の駆動電圧であることを特徴とす る請求の範囲第1項記載の同調光伝達ネットワーク。 5.前記発光ダイオードからの光エネルギに反応して、該光エネルギの強度を示す 出力信号を発生する検出器をさらに有することを特徴とする請求の範囲第1項記 載の同調光伝達ネットワーク。 6.光発生センサを事前較正する方法において、前記方法が: 事前選択された波長で光源を操作するために前記光源を通過するに必要な第1 の電流レベルを測定するステップと; 第2の電流レベルを定義するステップであり、前記第2の電流レベルが前記第1 の電流レベルより高く、さらに駆動電流を定義する第2の電流レベルを定義する ステップと; 前記光源と並列に結合すると同調光源ネットワークを形成するインピーダンス 素子を選択するステップであり、前記インピーダンス素子が、前記第1の電流レ ベルが該光源を通過するように前記駆動電流の充分な量を引き流すように選択さ れるステップと; 前記インピーダンスを前記光源と並列に接続するステップと; を有することを特徴とする方法。 7.単一発光ダイオードから2つの波長を提供する方法であり、前記方法が: ある範囲の駆動電流に対して該発光ダイオードを流れる駆動電流の変化に連れ て波長がシフトするタイプの発光ダイオードを選択するステップと; 前記駆動電流を提供するために該発光ダイオードに電気エネルギ源を結合する ステップと; 前記駆動電流範囲内の第1のレベルの駆動電流で該発光ダイオードを駆動し、 これによって、前記発光ダイオードをアクティブ状態にし、前記第1のレベルの 駆動電流に反応して第1の波長で動作させるステップと; 前記駆動電流範囲内にあるが前記第1のレベルの駆動電流とは異なる第2の駆動 電流で該発光ダイオードを駆動して、前記発光ダイオードをアクティブ状態にし 、前記第2のレベルの駆動電流に反応して第2の波長で動作させるステップと; を有することを特徴とする方法。 8.前記発光ダイオードが被検媒体に光エネルギを伝達するように構成される請求 の範囲第7項記載の方法において、前記方法が: 前記発光ダイオードが前記第1の波長で動作中に、前記第1の波長で第1の光エ ネルギを該被検媒体を介して伝達するステップであり、前記第1の波長が、該被 検媒体を伝搬するに際して前記光エネルギの事前決定された第1の減衰特性を持 つように選択されており、同時に、前記発光ダイオードからの該減衰した光エネ ルギを測定するステップと; 前記発光ダイオードが前記第2の波長で動作中に、前記第2の波長で第2の光エ ネルギを該被検媒体を介して伝達するステップであり、前記第2の波長が、該被 検媒体を伝搬するに際して前記光エネルギの事前決定された第2の減衰特性を持 つように選択されており、同時に、前記発光ダイオードからの該減衰した光エネ ルギを測定するステップと; を有することを特徴とする方法。 9.前記方法が血液の酸素飽和度を測定するステップを有し、前記被検媒体が、流 れている血液を持つ肉体の一部を有する請求の範囲第8項記載の方法において、 前記方法が: エネルギ源を、前記第1および第2の波長とな異なる第3の波長で動作する第2の 発光ダイオードに結合するステップであり、前記第1の波長と前記第2の波長の間 の変化が事前選択された値を持つステップと; 前記第3の波長で第3の光エネルギを前記被検媒体を介して伝達するステップと ; 前記第3の光エネルギを前記媒体を介して伝搬した後で測定するステップと; 前記血液の該酸素飽和度を計算ステップと; をさらに有することを特徴とする方法。 10.前記被検媒体、周知の値を持つ前記第1の波長および事前選択された値を持つ 前記第1の波長と前記第2の波長の間の波長の前記変化に関する別のパラメータを 計算するステップをさらに有する請求の範囲第9項記載の方法において: 前記第2の波長の値を決定するステップと; 前記血液の前記別のパラメータを計算するステップと; を有することを特徴とする方法。 11.前記別のパラメータがカルボキシヘモグロビンの飽和度を有することを特徴 とする請求の範囲第10項記載の方法。 12.前記別のパラメータが散乱を有することを特徴とする請求の範囲第10項記載 の方法。 13.前記方法が、該第1の発光ダイオードを、電流の段階的変化に対する波長の変 化が事前選択された波長変化に整合するように調節用インピーダンス素子で調節 するステップをさらに有することを特徴とする請求の範囲第7項記載の方法。 14.前記調節用インピーダンス素子が抵抗器を有することを特徴とする請求の範 囲第13項記載の方法。 15.前記調節ステップが: 前記発光ダイオードと並列に該調節用インピーダンス素子を置くステップと; 前記段階的電流変化に対する前記事前選択された変化を該第1の発光ダイオー ドが示すように、前記調節用抵抗器の値を選択するステップと; を有することを特徴とする請求の範囲第13項記載の方法。 16.第1の周知の波長で光を発生し、第1の電圧レベルでアクティブ状態となるよ うに構成された第1の発光装置と; 前記第1の発光装置と並列に置かれた情報素子と; を有することを特徴とするオキシメータ・センサ・ 17.前記情報素子が前記第1の電圧レベル未満の電圧レベルで動作することを特徴 とする請求の範囲第16項記載のオキシメータ・センサ。 18.前記情報素子が抵抗器を有することを特徴とする請求の範囲第16項記載のオ キシメータ・センサ。 19.前記情報素子がインピーダンス・ネットワークを有することを特徴とする請 求の範囲第16項記載のオキシメータ・センサ。 20.前記情報素子がメモリ装置を有することを特徴とする請求の範囲第16項記載 のオキシメータ・センサ。 21.該発光装置が発光ダイオードを有することを特徴とする請求の範囲第16項記 載のオキシメータ・センサ。 22.前記情報素子がエンコーディング抵抗器を有する請求の範囲第16項記載のオ キシメータ・センサにおいて、前記エンコーディング・センサの値が該第1の周 知の波長を示し、該値が、前記第1の発光装置のアクティブ動作中に実質的に電 流を該エンコーディング抵抗器が流さないほどに充分高いことを特徴とするオキ シメータ・センサ。 23.前記情報素子がセキュリティ素子を有する請求の範囲第16項記載のオキシメ ータ・センサにおいて、該セキュリティ素子が、該オキシメータ・センサが事前 決定されたタイプであることを示し、該セキュリティ素子の値が、前記発光装置 のアクティブな動作中に実質的に意味ある電流を流さないほどに充分高いことを 特徴とするオキシメータ・センサ。 24.前記セキュリティ素子が、前記第1の発光装置のアクティブな動作中に実質的 に意味のある電流を流さないほどに充分高い値を持つ抵抗を有することを特徴と する請求の範囲第23項記載のオキシメータ・センサ。 25.発光ダイオードを同調して、ある波長範囲内の事前選択された波長で動作さ せる方法において、前記方法が: ある駆動電流範囲内の駆動電流の変化に応じて波長がシフトする発光ダイオー ドを選択するステップと; 第1の駆動電流で前記発光ダイオードを駆動するステップと; 前記第1の駆動電流で動作中に前記発光ダイオードの波長を測定するステップ と; 前記事前選択された波長で前記発光ダイオードが動作していない場合に、前記 事前選択された波長で前記発光ダイオードが動作するように前記駆動電流範囲内 の該駆動電流を第2の駆動電流になるように調節するステップと; を有することを特徴とする方法。 26.少なくとも1つの発光素子であり、前記発光素子が中心伝達波長で放射する発 光素子と; 第1と第2の光検出器であり、前記第1と第2の光検出器の反応範囲内で前記放射 がなされる光検出器と; 前記少なくとも1つの発光素子から前記第1と第2の光検出器に光を出力するよ うに構成された光出力部材と; 前記第2の光検出器と前記少なくとも1つの発光素子の間に置かれたフィルタで あり、前記フィルタが前記中心伝達波長を範囲内に収めるように選択された伝達 帯域を持つフィルタと; を有する、光を伝達して検出するように構成されたセンサ。 27.前記センサがオキシメータ・センサを有し、前記少なくとも1つの発光素子が 第1と第2の発光ダイオードを有し、前記第1の発光ダイオードの中心波長が赤色 領域にあり、前記第2の発光ダイオードの中心波長が赤外線領域にあり、前記フ ィルタの遷移帯域が前記第1の発光ダイオードの中心波長を範囲に収めることを 特徴とする請求の範囲第26項記載のセンサ。 28.前記光出力部材が、前記少なくとも1つの発光素子から実質的に等しい部分の 光を受領するために積分光学球の周りに置かれた前記第1と第2の光検出器を持つ 積分光学球を有することを特徴とする請求の範囲第26項記載のセンサ。 29.前記光出力部材が、前記少なくとも1つの発光部材からの光を実質的に等しく 分割し、該光の実質的に等しい部分を前記第1と前記第2の光検出器に出力するよ うに置かれたビーム分割部材を有することを特徴とする請求の範囲第26項記載の センサ。 30.発光素子の中心波長を測定する方法において、前記方法が: 1セットの複数の事前決定された比を提供するステップであり、前記複数の事 前決定された比のおのおのが関連の中心波長に対応するステップと; 前記発光素子からの光を第1の光検出素子に伝達して、第1の強度を得るステッ プと; 前記発光素子からの光を、第2の光検出素子への該光を減衰するフィルタを介 して伝達して、第2の強度を得るステップと; 前記第2の強度の前記第1の強度に対する比を計算するステップと; 前記比を前記事前決定された比のセットと比較して、前記発光素子の中心波長 を参照するステップと; を有することを特徴とする方法。 31.前記第1と第2の光検出素子が同一の光検出素子を有し、前記伝達するステッ プが連続して発生することを特徴とする請求の範囲第30項記載の方法。
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US08/478,493 US5758644A (en) | 1995-06-07 | 1995-06-07 | Manual and automatic probe calibration |
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