JPH11500120A5 - - Google Patents

Info

Publication number
JPH11500120A5
JPH11500120A5 JP1996524648A JP52464896A JPH11500120A5 JP H11500120 A5 JPH11500120 A5 JP H11500120A5 JP 1996524648 A JP1996524648 A JP 1996524648A JP 52464896 A JP52464896 A JP 52464896A JP H11500120 A5 JPH11500120 A5 JP H11500120A5
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
JP1996524648A
Other languages
English (en)
Japanese (ja)
Other versions
JPH11500120A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/EP1996/000582 external-priority patent/WO1996025426A1/de
Publication of JPH11500120A publication Critical patent/JPH11500120A/ja
Publication of JPH11500120A5 publication Critical patent/JPH11500120A5/ja
Ceased legal-status Critical Current

Links

JP8524648A 1995-02-17 1996-02-12 新規なトロンビンインヒビター Ceased JPH11500120A (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
DE19505484 1995-02-17
DE19505484.9 1995-02-17
DE19506611 1995-02-24
DE19506611.1 1995-02-24
DE19507455.6 1995-03-03
DE19507455 1995-03-03
PCT/EP1996/000582 WO1996025426A1 (de) 1995-02-17 1996-02-12 Neue dipeptidische amidine als thrombin-inhibitoren

Publications (2)

Publication Number Publication Date
JPH11500120A JPH11500120A (ja) 1999-01-06
JPH11500120A5 true JPH11500120A5 (enExample) 2004-07-22

Family

ID=27214848

Family Applications (1)

Application Number Title Priority Date Filing Date
JP8524648A Ceased JPH11500120A (ja) 1995-02-17 1996-02-12 新規なトロンビンインヒビター

Country Status (26)

Country Link
US (3) US6030972A (enExample)
EP (1) EP0873356A1 (enExample)
JP (1) JPH11500120A (enExample)
KR (1) KR100388185B1 (enExample)
CN (1) CN1198839C (enExample)
AR (1) AR002277A1 (enExample)
AU (1) AU708001B2 (enExample)
BG (1) BG63697B1 (enExample)
BR (1) BR9607582A (enExample)
CA (1) CA2211109A1 (enExample)
CZ (1) CZ245797A3 (enExample)
EA (1) EA199700186A1 (enExample)
FI (1) FI973360A7 (enExample)
HR (1) HRP960075B1 (enExample)
HU (1) HUP9800263A3 (enExample)
IL (1) IL117165A0 (enExample)
MX (1) MX9706069A (enExample)
MY (1) MY132115A (enExample)
NO (1) NO973764L (enExample)
NZ (1) NZ302649A (enExample)
PL (1) PL321759A1 (enExample)
SI (1) SI9620037A (enExample)
SK (1) SK104697A3 (enExample)
TR (1) TR199700803T1 (enExample)
TW (1) TW450968B (enExample)
WO (1) WO1996025426A1 (enExample)

Families Citing this family (58)

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US5726159A (en) * 1994-03-04 1998-03-10 Eli Lilly And Company Antithrombotic agents
US5707966A (en) * 1994-03-04 1998-01-13 Eli Lilly And Company Antithrombotic agents
US5705487A (en) * 1994-03-04 1998-01-06 Eli Lilly And Company Antithrombotic agents
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US5914319A (en) * 1995-02-27 1999-06-22 Eli Lilly And Company Antithrombotic agents
US5710130A (en) * 1995-02-27 1998-01-20 Eli Lilly And Company Antithrombotic agents
SA96170106A (ar) 1995-07-06 2005-12-03 أسترا أكتيبولاج مشتقات حامض أميني جديدة
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US6200967B1 (en) 1996-06-25 2001-03-13 Eli Lilly And Company Anticoagulant agents
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SE9704543D0 (sv) * 1997-12-05 1997-12-05 Astra Ab New compounds
EP1049673A1 (de) * 1998-01-26 2000-11-08 Basf Aktiengesellschaft Heterocyclische amidine als kallikrein protease inhibitoren
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KR20020004995A (ko) * 1999-04-09 2002-01-16 스타르크, 카르크 트롬빈 억제제의 프로드럭
AU4111700A (en) * 1999-04-09 2000-11-14 Basf Aktiengesellschaft Low-molecular inhibitors of complement proteases
AR023510A1 (es) 1999-04-21 2002-09-04 Astrazeneca Ab Un equipo de partes, formulacion farmaceutica y uso de un inhibidor de trombina.
EP1054017B1 (de) * 1999-05-10 2004-10-13 Abbott GmbH & Co. KG Salze von Thrombininhibitoren
DE19921346A1 (de) 1999-05-10 2000-11-16 Basf Ag Sprühtrocknung von Thrombininhibitoren
SE0001803D0 (sv) 2000-05-16 2000-05-16 Astrazeneca Ab New compounds i
DE10029015A1 (de) 2000-06-15 2001-12-20 Curacyte Ag Hemmstoffe für den Gerinnungsfaktor Xa
US6433186B1 (en) 2000-08-16 2002-08-13 Astrazeneca Ab Amidino derivatives and their use as thormbin inhibitors
DE10049937A1 (de) * 2000-10-06 2002-04-11 Knoll Ag Niedermolekulare Inhibitoren von Serinproteasen mit Polyhydroxyalkyl- und Polyhydroxycycloalkylresten
AR035216A1 (es) * 2000-12-01 2004-05-05 Astrazeneca Ab Derivados de acido mandelico ,derivados farmaceuticamente aceptables, uso de estos derivados para la fabricacion de medicamentos, metodos de tratamiento ,procesos para la preparacion de estos derivados, y compuestos intermediarios
US7129233B2 (en) 2000-12-01 2006-10-31 Astrazeneca Ab Mandelic acid derivatives and their use as thrombin inhibitors
RU2300521C2 (ru) * 2000-12-01 2007-06-10 Астразенека Аб Новые производные миндальной кислоты и их применение в качестве ингибиторов тромбина
DE10064797A1 (de) * 2000-12-22 2002-06-27 Knoll Ag Orale und parenterale pharmazeutische Formulierung, umfassend eine niedermolekulare Thrombininhibitor-Pro-Pharmakon
US6774110B2 (en) * 2001-03-19 2004-08-10 Lg Life Sciences Ltd. Orally available peptidic thrombin inhibitors
AR034517A1 (es) * 2001-06-21 2004-02-25 Astrazeneca Ab Formulacion farmaceutica
DE10210590A1 (de) * 2002-03-11 2003-10-02 Curacyte Ag Hemmstoffe des Gerinnungsfaktors Xa, ihre Herstellung und Verwendung
ATE399175T1 (de) * 2002-03-11 2008-07-15 Curacyte Ag Hemmstoffe der urokinase, ihre herstellung und verwendung
WO2003086288A2 (en) 2002-04-12 2003-10-23 Merck & Co., Inc. Bicyclic amides
SE0201661D0 (sv) 2002-05-31 2002-05-31 Astrazeneca Ab New salts
SE0201659D0 (sv) * 2002-05-31 2002-05-31 Astrazeneca Ab Modified release pharmaceutical formulation
DE10301300B4 (de) 2003-01-15 2009-07-16 Curacyte Chemistry Gmbh Verwendung von acylierten 4-Amidino- und 4-Guanidinobenzylaminen zur Inhibierung von Plasmakallikrein
RU2228930C1 (ru) * 2003-05-20 2004-05-20 ООО "Исследовательский институт химического разнообразия" Замещенные 3-пиридилметиламины и фокусированная библиотека
US7781424B2 (en) * 2003-05-27 2010-08-24 Astrazeneca Ab Modified release pharmaceutical formulation
DE10342108A1 (de) 2003-09-11 2005-04-14 Curacyte Chemistry Gmbh Basisch-substituierte Benzylaminanaloga als Inhibitoren des Gerinnungsfaktors Xa, ihre Herstellung und Verwendung
JP2007510651A (ja) * 2003-11-04 2007-04-26 メルク　エンド　カムパニー　インコーポレーテッド 糖尿病の治療又は予防のためのジペプチジルペプチダーゼ−ｉｖ阻害剤としての縮合フェニルアラニン誘導体
US7795205B2 (en) * 2004-04-12 2010-09-14 Canyon Pharmaceuticals, Inc. Methods for effecting regression of tumor mass and size in a metastasized pancreatic tumor
WO2005111003A1 (en) 2004-04-29 2005-11-24 Abbott Laboratories Amino-tetrazoles analogues and methods of use
JP4561197B2 (ja) * 2004-06-28 2010-10-13 宇部興産株式会社 ５−（４−テトラヒドロピラニル）ヒダントインの製法及びその中間体
JP4572618B2 (ja) * 2004-08-04 2010-11-04 宇部興産株式会社 ４−テトラヒドロピラニルグリシンの製法
US7524354B2 (en) * 2005-07-07 2009-04-28 Research Foundation Of State University Of New York Controlled synthesis of highly monodispersed gold nanoparticles
DE102006050672A1 (de) * 2006-10-24 2008-04-30 Curacyte Discovery Gmbh Hemmstoffe des Plasmins und des Plasmakallikreins
TW200827336A (en) 2006-12-06 2008-07-01 Astrazeneca Ab New crystalline forms
US20090061000A1 (en) * 2007-08-31 2009-03-05 Astrazeneca Ab Pharmaceutical formulation use 030
CN102464701B (zh) * 2010-11-08 2015-10-21 上海医药工业研究院 一类新型化合物、其制备方法及用途
US12084472B2 (en) 2015-12-18 2024-09-10 Ardelyx, Inc. Substituted 4-phenyl pyridine compounds as non-systemic TGR5 agonists
TWI773657B (zh) 2015-12-18 2022-08-11 美商亞德利克斯公司 作爲非全身ｔｇｒ５促效劑之經取代之4-苯基吡啶化合物

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