JPH11292844A5 - - Google Patents
Info
- Publication number
- JPH11292844A5 JPH11292844A5 JP1999036063A JP3606399A JPH11292844A5 JP H11292844 A5 JPH11292844 A5 JP H11292844A5 JP 1999036063 A JP1999036063 A JP 1999036063A JP 3606399 A JP3606399 A JP 3606399A JP H11292844 A5 JPH11292844 A5 JP H11292844A5
- Authority
- JP
- Japan
- Prior art keywords
- mixture
- indoline
- acyl
- solvent
- ethanol
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NL1008302 | 1998-02-13 | ||
| NL1008302A NL1008302C2 (nl) | 1998-02-13 | 1998-02-13 | Werkwijze voor de bereiding van een optisch actief indoline-2-carbonzuur of derivaat daarvan. |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPH11292844A JPH11292844A (ja) | 1999-10-26 |
| JPH11292844A5 true JPH11292844A5 (enExample) | 2006-03-30 |
Family
ID=19766536
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP11036063A Pending JPH11292844A (ja) | 1998-02-13 | 1999-02-15 | 光学的に活性なインドリン―２―カルボン酸またはその誘導体の製造法 |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US6121460A (enExample) |
| EP (1) | EP0937714B1 (enExample) |
| JP (1) | JPH11292844A (enExample) |
| CN (1) | CN100383119C (enExample) |
| AT (1) | ATE278668T1 (enExample) |
| CA (1) | CA2261453C (enExample) |
| DE (1) | DE69920784T2 (enExample) |
| DK (1) | DK0937714T3 (enExample) |
| ES (1) | ES2230794T3 (enExample) |
| HU (1) | HU222432B1 (enExample) |
| IL (1) | IL128462A (enExample) |
| IN (1) | IN188422B (enExample) |
| NL (1) | NL1008302C2 (enExample) |
| PT (1) | PT937714E (enExample) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2001094334A1 (en) * | 2000-06-02 | 2001-12-13 | Eli Lilly & Company | Methods for resolving chiral (2s) and (2r) chromanes |
| DK1338591T3 (da) | 2003-02-28 | 2006-01-23 | Servier Lab | Fremgangsmåde til syntese af (2S,3aS,7aS)-perhydroindol-2-carboxylsyre og estere heraf samt anvendelse heraf ved syntese af perindopril |
| DE60301774T2 (de) * | 2003-02-28 | 2006-07-20 | Les Laboratoires Servier | Verfahren zur Synthese von (2S,3aS,7aS)-1-((S)-Alanyl)-octahydro-1H-indol-2-carbonsäurederivaten und Verwendung in der Synthese von Perindopril |
| KR100710539B1 (ko) | 2003-11-26 | 2007-04-24 | 에스케이 주식회사 | 가수분해 효소를 이용한 (ｓ)-인돌린-2-카르복실산 및이의 메틸 에스테르 화합물의 제조방법 |
| ES2366705T3 (es) * | 2004-12-28 | 2011-10-24 | Dsm Ip Assets B.V. | Procedimiento para la preparación de ácido indolin-2-carboxílico enriquecido enantioméricamente. |
| EP1676838A1 (en) * | 2004-12-28 | 2006-07-05 | DSM IP Assets B.V. | Process for the preparation of enantiomerically enriched indoline-2-carboxylic acid |
| EP1792896A1 (en) | 2005-12-01 | 2007-06-06 | KRKA, tovarna zdravil, d.d., Novo mesto | Process for the preparation of perindopril and salts thereof |
| US20100330625A1 (en) * | 2008-02-06 | 2010-12-30 | Mitsubishi Gas Chemical Company, Inc. | Process for production of optically active indoline-2-carboxylic acid or derivative thereof |
| CN102060745A (zh) * | 2010-11-23 | 2011-05-18 | 安徽世华化工有限公司 | 一种(s)-吲哚啉-2-羧酸的制备方法 |
| CN106631977A (zh) * | 2016-11-11 | 2017-05-10 | 上海雅本化学有限公司 | 一种s‑吲哚啉‑2‑羧酸合成的优化方法 |
| CN112375028A (zh) * | 2020-12-14 | 2021-02-19 | 安徽美诺华药物化学有限公司 | 合成（2s）-二氢吲哚-甲酸的方法 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4665087A (en) * | 1982-02-22 | 1987-05-12 | Ciba-Geigy Corporation | 1-(carbamyl, thiocarbamyl, and iminocarbamyl)-indoline derivatives |
| US4520205A (en) * | 1982-06-28 | 1985-05-28 | American Home Products Corporation | Chemical resolution of (+)-2,3-dihydroindole-2-carboxylic acid |
| JPH0798802B2 (ja) * | 1984-07-13 | 1995-10-25 | 東レ株式会社 | 光学活性インドリン―２―カルボン酸の製造法 |
| JPS6130572A (ja) * | 1984-07-20 | 1986-02-12 | Dainippon Pharmaceut Co Ltd | （ｒｓ）−１−アセチルインドリン−２−カルボン酸の光学分割法 |
| US5166361A (en) * | 1988-09-13 | 1992-11-24 | Sepracor, Inc. | Methods for preparing captopril and its analogues |
| US5149821A (en) * | 1990-10-11 | 1992-09-22 | Pfizer Inc | Process and intermediates for optically active 3-formyltetrahydropyrans |
| JPH06130572A (ja) * | 1992-10-22 | 1994-05-13 | Konica Corp | ハロゲン化銀写真感光材料処理用錠剤状定着剤及び該定着剤を用いた処理方法 |
-
1998
- 1998-02-13 NL NL1008302A patent/NL1008302C2/nl not_active IP Right Cessation
-
1999
- 1999-02-10 IL IL12846299A patent/IL128462A/xx not_active IP Right Cessation
- 1999-02-10 ES ES99200383T patent/ES2230794T3/es not_active Expired - Lifetime
- 1999-02-10 PT PT99200383T patent/PT937714E/pt unknown
- 1999-02-10 DK DK99200383T patent/DK0937714T3/da active
- 1999-02-10 DE DE69920784T patent/DE69920784T2/de not_active Expired - Lifetime
- 1999-02-10 EP EP99200383A patent/EP0937714B1/en not_active Expired - Lifetime
- 1999-02-10 AT AT99200383T patent/ATE278668T1/de not_active IP Right Cessation
- 1999-02-11 CA CA002261453A patent/CA2261453C/en not_active Expired - Fee Related
- 1999-02-12 US US09/249,025 patent/US6121460A/en not_active Expired - Fee Related
- 1999-02-12 IN IN179MA1999 patent/IN188422B/en unknown
- 1999-02-12 CN CNB991018923A patent/CN100383119C/zh not_active Expired - Fee Related
- 1999-02-12 HU HU9900344A patent/HU222432B1/hu not_active IP Right Cessation
- 1999-02-15 JP JP11036063A patent/JPH11292844A/ja active Pending
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