DK0937714T3 - Fremgangsmåde til fremstilling af en optisk aktiv indolin-2-carboxylsyre eller et derivat deraf - Google Patents

Fremgangsmåde til fremstilling af en optisk aktiv indolin-2-carboxylsyre eller et derivat deraf

Info

Publication number
DK0937714T3
DK0937714T3 DK99200383T DK99200383T DK0937714T3 DK 0937714 T3 DK0937714 T3 DK 0937714T3 DK 99200383 T DK99200383 T DK 99200383T DK 99200383 T DK99200383 T DK 99200383T DK 0937714 T3 DK0937714 T3 DK 0937714T3
Authority
DK
Denmark
Prior art keywords
indoline
carboxylic acid
derivative
acid
acyl
Prior art date
Application number
DK99200383T
Other languages
English (en)
Inventor
Andreas Joseph Johan Hendrickx
Thijs Kuilman
Original Assignee
Dsm Ip Assets Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dsm Ip Assets Bv filed Critical Dsm Ip Assets Bv
Application granted granted Critical
Publication of DK0937714T3 publication Critical patent/DK0937714T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Indole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK99200383T 1998-02-13 1999-02-10 Fremgangsmåde til fremstilling af en optisk aktiv indolin-2-carboxylsyre eller et derivat deraf DK0937714T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NL1008302A NL1008302C2 (nl) 1998-02-13 1998-02-13 Werkwijze voor de bereiding van een optisch actief indoline-2-carbonzuur of derivaat daarvan.

Publications (1)

Publication Number Publication Date
DK0937714T3 true DK0937714T3 (da) 2005-02-07

Family

ID=19766536

Family Applications (1)

Application Number Title Priority Date Filing Date
DK99200383T DK0937714T3 (da) 1998-02-13 1999-02-10 Fremgangsmåde til fremstilling af en optisk aktiv indolin-2-carboxylsyre eller et derivat deraf

Country Status (14)

Country Link
US (1) US6121460A (da)
EP (1) EP0937714B1 (da)
JP (1) JPH11292844A (da)
CN (1) CN100383119C (da)
AT (1) ATE278668T1 (da)
CA (1) CA2261453C (da)
DE (1) DE69920784T2 (da)
DK (1) DK0937714T3 (da)
ES (1) ES2230794T3 (da)
HU (1) HU222432B1 (da)
IL (1) IL128462A (da)
IN (1) IN188422B (da)
NL (1) NL1008302C2 (da)
PT (1) PT937714E (da)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001094334A1 (en) * 2000-06-02 2001-12-13 Eli Lilly & Company Methods for resolving chiral (2s) and (2r) chromanes
SI1403277T1 (sl) * 2003-02-28 2005-12-31 Servier Lab NOV POSTOPEK ZA SINTEZO DERIVATOV (2S, 3aS, 7aS)-1-((S)-ALANIL)-OKTAHIDRO-1H-INDOL-2-KARBOKSILNE KISLINE IN UPORABA PRI SINTEZI PERINDOPRILA
DE60301980T2 (de) * 2003-02-28 2006-07-27 Les Laboratoires Servier Verfahren zur Synthese des (2S,3aS,7aS)-perhydroindol-2-carbonsäures und seiner Estern, Verwendung in der Synthese von Perindopril
KR100710539B1 (ko) 2003-11-26 2007-04-24 에스케이 주식회사 가수분해 효소를 이용한 (ｓ)-인돌린-2-카르복실산 및이의 메틸 에스테르 화합물의 제조방법
ATE515496T1 (de) * 2004-12-28 2011-07-15 Dsm Ip Assets Bv Verfahren zur herstellung von enantiomerenangereicherter indolin-2-carbonsäure
EP1676838A1 (en) * 2004-12-28 2006-07-05 DSM IP Assets B.V. Process for the preparation of enantiomerically enriched indoline-2-carboxylic acid
EP1792896A1 (en) 2005-12-01 2007-06-06 KRKA, tovarna zdravil, d.d., Novo mesto Process for the preparation of perindopril and salts thereof
CN101939444A (zh) * 2008-02-06 2011-01-05 三菱瓦斯化学株式会社 光学活性二氢吲哚-2-羧酸或其衍生物的制备方法
CN102060745A (zh) * 2010-11-23 2011-05-18 安徽世华化工有限公司 一种(s)-吲哚啉-2-羧酸的制备方法
CN106631977A (zh) * 2016-11-11 2017-05-10 上海雅本化学有限公司 一种s‑吲哚啉‑2‑羧酸合成的优化方法
CN112375028A (zh) * 2020-12-14 2021-02-19 安徽美诺华药物化学有限公司 合成（2s）-二氢吲哚-甲酸的方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4665087A (en) * 1982-02-22 1987-05-12 Ciba-Geigy Corporation 1-(carbamyl, thiocarbamyl, and iminocarbamyl)-indoline derivatives
US4520205A (en) * 1982-06-28 1985-05-28 American Home Products Corporation Chemical resolution of (+)-2,3-dihydroindole-2-carboxylic acid
JPH0798802B2 (ja) * 1984-07-13 1995-10-25 東レ株式会社 光学活性インドリン―２―カルボン酸の製造法
JPS6130572A (ja) * 1984-07-20 1986-02-12 Dainippon Pharmaceut Co Ltd （ｒｓ）−１−アセチルインドリン−２−カルボン酸の光学分割法
US5166361A (en) * 1988-09-13 1992-11-24 Sepracor, Inc. Methods for preparing captopril and its analogues
US5149821A (en) * 1990-10-11 1992-09-22 Pfizer Inc Process and intermediates for optically active 3-formyltetrahydropyrans
JPH06130572A (ja) * 1992-10-22 1994-05-13 Konica Corp ハロゲン化銀写真感光材料処理用錠剤状定着剤及び該定着剤を用いた処理方法

Also Published As

Publication number Publication date
HU222432B1 (hu) 2003-07-28
CA2261453C (en) 2009-05-12
NL1008302C2 (nl) 1999-08-16
ES2230794T3 (es) 2005-05-01
CN1228423A (zh) 1999-09-15
HU9900344D0 (en) 1999-04-28
ATE278668T1 (de) 2004-10-15
CN100383119C (zh) 2008-04-23
US6121460A (en) 2000-09-19
IL128462A0 (en) 2000-01-31
PT937714E (pt) 2005-02-28
EP0937714A1 (en) 1999-08-25
DE69920784D1 (de) 2004-11-11
CA2261453A1 (en) 1999-08-13
EP0937714B1 (en) 2004-10-06
IN188422B (da) 2002-09-21
HUP9900344A3 (en) 2000-03-28
IL128462A (en) 2003-07-31
JPH11292844A (ja) 1999-10-26
DE69920784T2 (de) 2005-11-03
HUP9900344A2 (hu) 1999-10-28

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