NL1008302C2 - Werkwijze voor de bereiding van een optisch actief indoline-2-carbonzuur of derivaat daarvan. - Google Patents
Werkwijze voor de bereiding van een optisch actief indoline-2-carbonzuur of derivaat daarvan. Download PDFInfo
- Publication number
- NL1008302C2 NL1008302C2 NL1008302A NL1008302A NL1008302C2 NL 1008302 C2 NL1008302 C2 NL 1008302C2 NL 1008302 A NL1008302 A NL 1008302A NL 1008302 A NL1008302 A NL 1008302A NL 1008302 C2 NL1008302 C2 NL 1008302C2
- Authority
- NL
- Netherlands
- Prior art keywords
- indoline
- carboxylic acid
- acid
- derivative
- acyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Indole Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Priority Applications (14)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
NL1008302A NL1008302C2 (nl) | 1998-02-13 | 1998-02-13 | Werkwijze voor de bereiding van een optisch actief indoline-2-carbonzuur of derivaat daarvan. |
DE69920784T DE69920784T2 (de) | 1998-02-13 | 1999-02-10 | Verfahren zur Herstellung von optisch aktiver Indolin-2-carbon-säurens oder eines Derivats |
EP99200383A EP0937714B1 (en) | 1998-02-13 | 1999-02-10 | Process for the preparation of an optically active indoline-2-carboxylic acid or derivative thereof |
PT99200383T PT937714E (pt) | 1998-02-13 | 1999-02-10 | Processo para a preparacao de um acido indolina-2-carboxilico opticamente activo ou um seu derivado |
DK99200383T DK0937714T3 (da) | 1998-02-13 | 1999-02-10 | Fremgangsmåde til fremstilling af en optisk aktiv indolin-2-carboxylsyre eller et derivat deraf |
ES99200383T ES2230794T3 (es) | 1998-02-13 | 1999-02-10 | Proceso para la preparacion de un acido indolin-2-carboxilico opticamente activo o un derivado suyo. |
AT99200383T ATE278668T1 (de) | 1998-02-13 | 1999-02-10 | Verfahren zur herstellung von optisch aktives indolin-2-carbonsäures oder eines derivates |
IL12846299A IL128462A (en) | 1998-02-13 | 1999-02-10 | Process for the preparation of an optically active n-acyl-indoline-2-carboxylic acid or derivative thereof |
CA002261453A CA2261453C (en) | 1998-02-13 | 1999-02-11 | Process for the preparation of an optically active indoline-2-carboxylic acid or derivative thereof |
HU9900344A HU222432B1 (hu) | 1998-02-13 | 1999-02-12 | Eljárás optikailag aktív indolin-2-karbonsavnak vagy származékának előállítására |
IN179MA1999 IN188422B (da) | 1998-02-13 | 1999-02-12 | |
US09/249,025 US6121460A (en) | 1998-02-13 | 1999-02-12 | Process for the preparation of an optically active indoline-2-carboxylic acid or derivative thereof |
CNB991018923A CN100383119C (zh) | 1998-02-13 | 1999-02-12 | 旋光二氢吲哚-2-羧酸或其衍生物的制备方法 |
JP11036063A JPH11292844A (ja) | 1998-02-13 | 1999-02-15 | 光学的に活性なインドリン―2―カルボン酸またはその誘導体の製造法 |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
NL1008302 | 1998-02-13 | ||
NL1008302A NL1008302C2 (nl) | 1998-02-13 | 1998-02-13 | Werkwijze voor de bereiding van een optisch actief indoline-2-carbonzuur of derivaat daarvan. |
Publications (1)
Publication Number | Publication Date |
---|---|
NL1008302C2 true NL1008302C2 (nl) | 1999-08-16 |
Family
ID=19766536
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NL1008302A NL1008302C2 (nl) | 1998-02-13 | 1998-02-13 | Werkwijze voor de bereiding van een optisch actief indoline-2-carbonzuur of derivaat daarvan. |
Country Status (14)
Country | Link |
---|---|
US (1) | US6121460A (da) |
EP (1) | EP0937714B1 (da) |
JP (1) | JPH11292844A (da) |
CN (1) | CN100383119C (da) |
AT (1) | ATE278668T1 (da) |
CA (1) | CA2261453C (da) |
DE (1) | DE69920784T2 (da) |
DK (1) | DK0937714T3 (da) |
ES (1) | ES2230794T3 (da) |
HU (1) | HU222432B1 (da) |
IL (1) | IL128462A (da) |
IN (1) | IN188422B (da) |
NL (1) | NL1008302C2 (da) |
PT (1) | PT937714E (da) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2001266678A1 (en) * | 2000-06-02 | 2001-12-17 | Eli Lilly And Company | Methods for resolving chiral (2s) and (2r) chromanes |
DE60301980T2 (de) * | 2003-02-28 | 2006-07-27 | Les Laboratoires Servier | Verfahren zur Synthese des (2S,3aS,7aS)-perhydroindol-2-carbonsäures und seiner Estern, Verwendung in der Synthese von Perindopril |
ES2249691T3 (es) * | 2003-02-28 | 2006-04-01 | Les Laboratoires Servier | Procedimiento de sintesis de derivados del acido (2s,3as,7as)-1-(s)-alanil)-octahidro-1h-indol-2-carboxilico y su utilizacion en la sintesis de perindopril. |
KR100710539B1 (ko) | 2003-11-26 | 2007-04-24 | 에스케이 주식회사 | 가수분해 효소를 이용한 (s)-인돌린-2-카르복실산 및이의 메틸 에스테르 화합물의 제조방법 |
WO2006069799A1 (en) * | 2004-12-28 | 2006-07-06 | Dsm Ip Assets B.V. | Process for the preparation of enantiomerically enriched indoline-2-carboxylic acid |
EP1676838A1 (en) * | 2004-12-28 | 2006-07-05 | DSM IP Assets B.V. | Process for the preparation of enantiomerically enriched indoline-2-carboxylic acid |
EP1792896A1 (en) | 2005-12-01 | 2007-06-06 | KRKA, tovarna zdravil, d.d., Novo mesto | Process for the preparation of perindopril and salts thereof |
JP5093248B2 (ja) * | 2008-02-06 | 2012-12-12 | 三菱瓦斯化学株式会社 | 光学活性インドリン−2−カルボン酸類またはその誘導体の製造方法 |
CN102060745A (zh) * | 2010-11-23 | 2011-05-18 | 安徽世华化工有限公司 | 一种(s)-吲哚啉-2-羧酸的制备方法 |
CN106631977A (zh) * | 2016-11-11 | 2017-05-10 | 上海雅本化学有限公司 | 一种s‑吲哚啉‑2‑羧酸合成的优化方法 |
CN112375028A (zh) * | 2020-12-14 | 2021-02-19 | 安徽美诺华药物化学有限公司 | 合成(2s)-二氢吲哚-甲酸的方法 |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4520205A (en) * | 1982-06-28 | 1985-05-28 | American Home Products Corporation | Chemical resolution of (+)-2,3-dihydroindole-2-carboxylic acid |
EP0171616A1 (en) * | 1984-07-13 | 1986-02-19 | Toray Industries, Inc. | The use of alpha-amino-epsilon-caprolactam as a resolving agent for N-acetylindoline-2-carboxylic acid and method for preparing optically active N-acetylindoline-2-carboxylic acid |
US4665087A (en) * | 1982-02-22 | 1987-05-12 | Ciba-Geigy Corporation | 1-(carbamyl, thiocarbamyl, and iminocarbamyl)-indoline derivatives |
JPH06130572A (ja) * | 1992-10-22 | 1994-05-13 | Konica Corp | ハロゲン化銀写真感光材料処理用錠剤状定着剤及び該定着剤を用いた処理方法 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS6130572A (ja) * | 1984-07-20 | 1986-02-12 | Dainippon Pharmaceut Co Ltd | (rs)−1−アセチルインドリン−2−カルボン酸の光学分割法 |
US5166361A (en) * | 1988-09-13 | 1992-11-24 | Sepracor, Inc. | Methods for preparing captopril and its analogues |
US5149821A (en) * | 1990-10-11 | 1992-09-22 | Pfizer Inc | Process and intermediates for optically active 3-formyltetrahydropyrans |
-
1998
- 1998-02-13 NL NL1008302A patent/NL1008302C2/nl not_active IP Right Cessation
-
1999
- 1999-02-10 ES ES99200383T patent/ES2230794T3/es not_active Expired - Lifetime
- 1999-02-10 EP EP99200383A patent/EP0937714B1/en not_active Expired - Lifetime
- 1999-02-10 IL IL12846299A patent/IL128462A/xx not_active IP Right Cessation
- 1999-02-10 PT PT99200383T patent/PT937714E/pt unknown
- 1999-02-10 AT AT99200383T patent/ATE278668T1/de not_active IP Right Cessation
- 1999-02-10 DE DE69920784T patent/DE69920784T2/de not_active Expired - Lifetime
- 1999-02-10 DK DK99200383T patent/DK0937714T3/da active
- 1999-02-11 CA CA002261453A patent/CA2261453C/en not_active Expired - Fee Related
- 1999-02-12 HU HU9900344A patent/HU222432B1/hu not_active IP Right Cessation
- 1999-02-12 US US09/249,025 patent/US6121460A/en not_active Expired - Fee Related
- 1999-02-12 IN IN179MA1999 patent/IN188422B/en unknown
- 1999-02-12 CN CNB991018923A patent/CN100383119C/zh not_active Expired - Fee Related
- 1999-02-15 JP JP11036063A patent/JPH11292844A/ja active Pending
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4665087A (en) * | 1982-02-22 | 1987-05-12 | Ciba-Geigy Corporation | 1-(carbamyl, thiocarbamyl, and iminocarbamyl)-indoline derivatives |
US4520205A (en) * | 1982-06-28 | 1985-05-28 | American Home Products Corporation | Chemical resolution of (+)-2,3-dihydroindole-2-carboxylic acid |
EP0171616A1 (en) * | 1984-07-13 | 1986-02-19 | Toray Industries, Inc. | The use of alpha-amino-epsilon-caprolactam as a resolving agent for N-acetylindoline-2-carboxylic acid and method for preparing optically active N-acetylindoline-2-carboxylic acid |
JPH06130572A (ja) * | 1992-10-22 | 1994-05-13 | Konica Corp | ハロゲン化銀写真感光材料処理用錠剤状定着剤及び該定着剤を用いた処理方法 |
Non-Patent Citations (1)
Title |
---|
CHEMICAL ABSTRACTS, vol. 105, no. 7, 18 August 1986, Columbus, Ohio, US; abstract no. 60525w, TSUKAMOTO,MASATOSHI ET AL.: "Optical resolution of (RS)-1-acetyl-2-carboxylic acid" XP002079597 * |
Also Published As
Publication number | Publication date |
---|---|
IL128462A0 (en) | 2000-01-31 |
HU9900344D0 (en) | 1999-04-28 |
HU222432B1 (hu) | 2003-07-28 |
ES2230794T3 (es) | 2005-05-01 |
EP0937714A1 (en) | 1999-08-25 |
US6121460A (en) | 2000-09-19 |
CA2261453A1 (en) | 1999-08-13 |
CN1228423A (zh) | 1999-09-15 |
DE69920784T2 (de) | 2005-11-03 |
HUP9900344A3 (en) | 2000-03-28 |
IL128462A (en) | 2003-07-31 |
HUP9900344A2 (hu) | 1999-10-28 |
DE69920784D1 (de) | 2004-11-11 |
ATE278668T1 (de) | 2004-10-15 |
CA2261453C (en) | 2009-05-12 |
DK0937714T3 (da) | 2005-02-07 |
IN188422B (da) | 2002-09-21 |
EP0937714B1 (en) | 2004-10-06 |
JPH11292844A (ja) | 1999-10-26 |
CN100383119C (zh) | 2008-04-23 |
PT937714E (pt) | 2005-02-28 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
VD1 | Lapsed due to non-payment of the annual fee |
Effective date: 20020901 |