JPH10287651A5 - - Google Patents

Info

Publication number
JPH10287651A5
JPH10287651A5 JP1998107161A JP10716198A JPH10287651A5 JP H10287651 A5 JPH10287651 A5 JP H10287651A5 JP 1998107161 A JP1998107161 A JP 1998107161A JP 10716198 A JP10716198 A JP 10716198A JP H10287651 A5 JPH10287651 A5 JP H10287651A5
Authority
JP
Japan
Prior art keywords
alkyl
fluorine
cooh
coor11
phenyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP1998107161A
Other languages
English (en)
Japanese (ja)
Other versions
JP4234805B2 (ja
JPH10287651A (ja
Filing date
Publication date
Priority claimed from DE1998102530 external-priority patent/DE19802530A1/de
Application filed filed Critical
Publication of JPH10287651A publication Critical patent/JPH10287651A/ja
Publication of JPH10287651A5 publication Critical patent/JPH10287651A5/ja
Application granted granted Critical
Publication of JP4234805B2 publication Critical patent/JP4234805B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

JP10716198A 1997-04-04 1998-04-03 プロパノールアミン誘導体、それらの製法、それらを含有する薬剤およびそれらの使用 Expired - Fee Related JP4234805B2 (ja)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE19713865 1997-04-04
DE19802530:0 1998-01-26
DE1998102530 DE19802530A1 (de) 1998-01-26 1998-01-26 Propanolaminderivate, Verfahren zu deren Herstellung, diese Verbindungen enthaltende Arzneimittel und deren Verwendung
DE19713865:9 1998-01-26

Publications (3)

Publication Number Publication Date
JPH10287651A JPH10287651A (ja) 1998-10-27
JPH10287651A5 true JPH10287651A5 (https=) 2005-09-08
JP4234805B2 JP4234805B2 (ja) 2009-03-04

Family

ID=26035472

Family Applications (1)

Application Number Title Priority Date Filing Date
JP10716198A Expired - Fee Related JP4234805B2 (ja) 1997-04-04 1998-04-03 プロパノールアミン誘導体、それらの製法、それらを含有する薬剤およびそれらの使用

Country Status (23)

Country Link
US (1) US5874451A (https=)
EP (1) EP0869121B1 (https=)
JP (1) JP4234805B2 (https=)
KR (1) KR19980081055A (https=)
CN (1) CN1185217C (https=)
AR (1) AR011210A1 (https=)
AT (1) ATE268758T1 (https=)
AU (1) AU730228B2 (https=)
BR (1) BR9801150A (https=)
CA (1) CA2233925A1 (https=)
CZ (1) CZ293758B6 (https=)
DE (1) DE59811528D1 (https=)
DK (1) DK0869121T3 (https=)
ES (1) ES2223091T3 (https=)
HU (1) HUP9800781A3 (https=)
ID (1) ID20137A (https=)
IL (1) IL123927A (https=)
MY (1) MY114944A (https=)
NZ (1) NZ330110A (https=)
PL (1) PL325699A1 (https=)
PT (1) PT869121E (https=)
RU (1) RU2198876C2 (https=)
TR (1) TR199800608A2 (https=)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19845402B4 (de) 1998-10-02 2005-04-07 Aventis Pharma Deutschland Gmbh Mit Heterocyclen substituierte Propanolaminderivate, Verfahren zu deren Herstellung, diese Verbindungen enthaltende Arzneimittel und deren Verwendung
US7045519B2 (en) * 1998-06-19 2006-05-16 Chiron Corporation Inhibitors of glycogen synthase kinase 3
WO1999065897A1 (en) 1998-06-19 1999-12-23 Chiron Corporation Inhibitors of glycogen synthase kinase 3
DE19845403B4 (de) 1998-10-02 2005-02-10 Aventis Pharma Deutschland Gmbh Mit Gallensäuren verknüpfte Propanolaminderivate, Verfahren zu deren Herstellung, diese Verbindungen enthaltende Arzneimittel und deren Verwendung
DE19845406C2 (de) 1998-10-02 2001-10-18 Aventis Pharma Gmbh Substituierte 1,3-Diaryl-2-pyridin-2-yl-3-(pyridin-2-ylamino)- propanolderivate, Verfahren zu deren Herstellung, diese Verbindungen enthaltende Arzneimittel und deren Verwendung
DE19845405C2 (de) 1998-10-02 2000-07-13 Aventis Pharma Gmbh Arylsubstituierte Propanolaminderivate und deren Verwendung
MXPA03005019A (es) 2000-12-21 2003-09-25 Avantis Pharma Deutschland Gmb Derivados de difenilazetidinonas, metodo para su produccion farmacos que contienen estos compuestos y su uso.
EP1420826A2 (de) * 2001-08-22 2004-05-26 Aventis Pharma Deutschland GmbH Kombinationspräparate von arylsubstituierten propanolaminderivaten mit weiteren wirkstoffen und deren verwendung
US7820682B2 (en) 2002-10-03 2010-10-26 Ono Pharmaceutical Co., Ltd. LPA receptor antagonist
GB0307918D0 (en) 2003-04-05 2003-05-14 Astrazeneca Ab Therapeutic use
ATE528276T1 (de) * 2003-12-19 2011-10-15 Ono Pharmaceutical Co Lysophosphatidylsäurerezeptor-antagonistische verbindungen und ihre anwendungen
CN1869002A (zh) * 2005-05-27 2006-11-29 中国科学院上海药物研究所 一类非甾体雄激素受体调节剂、其制备方法和用途
US8461161B2 (en) * 2006-11-15 2013-06-11 Ym Biosciences Australia Pty Ltd Substituted pyrazines as inhibitors of kinase activity
ES2552657T3 (es) 2010-05-26 2015-12-01 Satiogen Pharmaceuticals, Inc. Inhibidores del reciclado de ácidos biliares y saciógenos para el tratamiento de diabetes, obesidad, y afecciones gastrointestinales inflamatorias
US20130108573A1 (en) 2011-10-28 2013-05-02 Lumena Pharmaceuticals, Inc. Bile Acid Recycling Inhibitors for Treatment of Hypercholemia and Cholestatic Liver Disease
AU2012328526B2 (en) 2011-10-28 2017-05-25 Shire Human Genetic Therapies, Inc. Bile acid recycling inhibitors for treatment of pediatric cholestatic liver diseases
AU2014229050A1 (en) 2013-03-15 2015-10-22 Lumena Pharmaceuticals Llc Bile acid recycling inhibitors for treatment of Barrett's esophagus and gastroesophageal reflux disease
CA2907230A1 (en) 2013-03-15 2014-09-18 Lumena Pharmaceuticals, Inc. Bile acid recycling inhibitors for treatment of primary sclerosing cholangitis and inflammatory bowel disease
CN105553262B (zh) * 2015-08-24 2018-02-16 苏州瑞铬优电子科技有限公司 一种提高dc/dc升压变换器转换效率的方法
EP3923943B1 (en) 2019-02-12 2024-07-31 Mirum Pharmaceuticals, Inc. Genotype and dose-dependent response to an asbti in patients with bile salt export pump deficiency

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI892341L (fi) * 1988-06-10 1989-12-11 Hoffmann La Roche Propanolaminderivat.
US5250524A (en) * 1990-12-06 1993-10-05 Hoechst Aktiengesellschaft Bile acid derivatives, process for their preparation and use of these compounds as pharmaceuticals
DE4040026A1 (de) * 1990-12-14 1992-06-17 Bayer Ag Substituierte pyridyl-dihydroxy-heptensaeure und deren salze
GB9203347D0 (en) * 1992-02-17 1992-04-01 Wellcome Found Hypolipidaemic compounds
ATE147384T1 (de) * 1992-02-22 1997-01-15 Hoechst Ag 4-amino-2-ureido-pyrimidin-5-carbonsäureamide, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung

Similar Documents

Publication Publication Date Title
JPH10287651A5 (https=)
US20040259842A1 (en) Intracellular calcuim concentration increase inhibitors
JP2005508905A5 (https=)
JP2006526031A5 (https=)
JP2005525294A5 (https=)
JP2002332234A5 (https=)
CA2345369A1 (en) Aryl-substituted propanolamine derivatives, their preparation, pharmaceuticals comprising them, and their use
JP2009506014A5 (https=)
JP2004516314A5 (https=)
JP2012506896A5 (https=)
JP2005511698A5 (https=)
JP2008533191A5 (https=)
JP2005518405A5 (https=)
JP2002513793A5 (https=)
JP2002030084A5 (https=)
JP2002527474A5 (ja) 躁病および双極性障害の治療のための医薬
JP2005536519A5 (https=)
JP2003503449A5 (https=)
JP2014505017A5 (https=)
JP2002527414A5 (https=)
JPWO2023195529A5 (https=)
JP2002526539A5 (https=)
JP2005505583A5 (https=)
JP2008513510A5 (https=)
JP2007515467A5 (https=)