JPH10262686A5 - - Google Patents

Info

Publication number
JPH10262686A5
JPH10262686A5 JP1997329715A JP32971597A JPH10262686A5 JP H10262686 A5 JPH10262686 A5 JP H10262686A5 JP 1997329715 A JP1997329715 A JP 1997329715A JP 32971597 A JP32971597 A JP 32971597A JP H10262686 A5 JPH10262686 A5 JP H10262686A5
Authority
JP
Japan
Prior art keywords
japanese patent
wild
polypeptide
patent application
type polypeptide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP1997329715A
Other languages
English (en)
Japanese (ja)
Other versions
JPH10262686A (ja
JP4024366B2 (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from JP32971597A external-priority patent/JP4024366B2/ja
Priority to JP32971597A priority Critical patent/JP4024366B2/ja
Priority to TW086117857A priority patent/TW565569B/zh
Priority to EP97309632A priority patent/EP0845530A3/en
Priority to KR1019970064563A priority patent/KR100496460B1/ko
Priority to US08/982,285 priority patent/US6476197B1/en
Publication of JPH10262686A publication Critical patent/JPH10262686A/ja
Priority to US10/260,576 priority patent/US7037685B2/en
Publication of JPH10262686A5 publication Critical patent/JPH10262686A5/ja
Publication of JP4024366B2 publication Critical patent/JP4024366B2/ja
Application granted granted Critical
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

JP32971597A 1996-11-29 1997-11-14 ポリペプチド Expired - Fee Related JP4024366B2 (ja)

Priority Applications (6)

Application Number Priority Date Filing Date Title
JP32971597A JP4024366B2 (ja) 1996-11-29 1997-11-14 ポリペプチド
TW086117857A TW565569B (en) 1996-11-29 1997-11-27 Novel polypeptides for inducing the production of interferon-gamma
EP97309632A EP0845530A3 (en) 1996-11-29 1997-11-28 Interferon gamma inducing factor
KR1019970064563A KR100496460B1 (ko) 1996-11-29 1997-11-29 폴리펩티드
US08/982,285 US6476197B1 (en) 1996-11-29 1997-12-01 Polypeptides having interferon-γ inducing activity
US10/260,576 US7037685B2 (en) 1996-11-29 2002-10-01 DNA encoding loypeptides having interferon-γ inducing activity

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
JP33303796 1996-11-29
JP9-20906 1997-01-21
JP8-333037 1997-01-21
JP2090697 1997-01-21
JP32971597A JP4024366B2 (ja) 1996-11-29 1997-11-14 ポリペプチド

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2007006295A Division JP2007143555A (ja) 1996-11-29 2007-01-15 ポリペプチド

Publications (3)

Publication Number Publication Date
JPH10262686A JPH10262686A (ja) 1998-10-06
JPH10262686A5 true JPH10262686A5 (enExample) 2004-11-18
JP4024366B2 JP4024366B2 (ja) 2007-12-19

Family

ID=27283214

Family Applications (1)

Application Number Title Priority Date Filing Date
JP32971597A Expired - Fee Related JP4024366B2 (ja) 1996-11-29 1997-11-14 ポリペプチド

Country Status (5)

Country Link
US (2) US6476197B1 (enExample)
EP (1) EP0845530A3 (enExample)
JP (1) JP4024366B2 (enExample)
KR (1) KR100496460B1 (enExample)
TW (1) TW565569B (enExample)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69519454T2 (de) * 1994-07-14 2001-05-03 Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo, Okayama Protein, das Interferon-Gamma Herstellung induziert und monoklonaler Antikörper dagegen
JP3955352B2 (ja) 1997-02-25 2007-08-08 株式会社林原生物化学研究所 破骨細胞形成阻害剤
TWI227136B (en) * 1998-05-21 2005-02-01 Smithkline Beecham Corp Novel pharmaceutical composition for the prevention and/or treatment of cancer
AU761520B2 (en) * 1998-09-15 2003-06-05 Genetics Institute, Llc Treatment of Kaposi's Sarcoma with IL-12
US6432678B1 (en) 1999-06-21 2002-08-13 Smithkline Beecham Corporation Macaca cynomolgus IL 18
SK12942002A3 (sk) * 2000-02-10 2003-05-02 Abbott Laboratories Protilátky viažuce ľudský interleukín-18, spôsoby ich výroby a použitia
JP2004530432A (ja) * 2001-03-08 2004-10-07 アレス・トレーディング・ソシエテ・アノニム インターロイキン−１８変異体、その産生および使用
AU2002326961A1 (en) * 2001-10-10 2003-04-22 Centocor, Inc. Nucleic acid vaccines using tumor antigen encoding nucleic acids with cytokine adjuvant encoding nucleic acid
KR100468482B1 (ko) * 2002-04-11 2005-01-27 양문식 효모 발현 시스템을 이용한 인터루킨-18 단백질의생산방법
US20050079153A1 (en) * 2002-08-14 2005-04-14 Pfizer Inc. Methods for enhancing immune functions in neonatal mammals by administration of IL-18
EP1613274B1 (en) 2003-04-15 2010-03-03 GlaxoSmithKline LLC Human il-18 substitution mutants and their conjugates
US7968684B2 (en) * 2003-11-12 2011-06-28 Abbott Laboratories IL-18 binding proteins
WO2005075648A1 (en) * 2004-01-28 2005-08-18 Gifu University Interleukin-18 mutant proteins
ATE526057T1 (de) * 2004-08-20 2011-10-15 Glaxosmithkline Llc Wundheilung durch verabreichung von menschlichem il-18
AR065803A1 (es) * 2007-03-23 2009-07-01 Smithkline Beecham Corp Uso de un polipeptido de il- 18 humana y un anticuerpo anti- cd para preparar unmedicamento
JP2018505320A (ja) * 2015-01-14 2018-02-22 バスカーク、 グレゴリー ヴァン しみ抜きのための改善された布地の処理方法
JP7795181B2 (ja) 2017-09-06 2026-01-07 イェール ユニバーシティー インターロイキン－１８バリアントとその利用法
US12029778B2 (en) 2019-05-13 2024-07-09 Yale University Interleukin-18 mimics and methods of use
KR20230117120A (ko) 2020-11-02 2023-08-07 심카 아이엘-18, 인크. 인터류킨-18 변이체 및 사용 방법
CN116848130A (zh) 2021-02-10 2023-10-03 国立大学法人长崎大学 新型人白细胞介素-18突变体及其用途
JP7849832B2 (ja) 2021-08-06 2026-04-22 国立大学法人 長崎大学 がんの治療剤
JP2024546930A (ja) * 2021-12-15 2024-12-26 ジェネンテック， インコーポレイテッド 安定化ｉｌ－１８ポリペプチド及びその使用
US12134635B1 (en) 2023-12-29 2024-11-05 Sonnet BioTherapeutics, Inc. Interleukin 18 (IL-18) variants and fusion proteins comprising same

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4518546A (en) * 1982-06-18 1985-05-21 General Electric Company Preparation of yttria-gadolinia ceramic scintillators by sintering and gas hot isostatic pressing
US4518584A (en) * 1983-04-15 1985-05-21 Cetus Corporation Human recombinant interleukin-2 muteins
DE69519454T2 (de) * 1994-07-14 2001-05-03 Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo, Okayama Protein, das Interferon-Gamma Herstellung induziert und monoklonaler Antikörper dagegen
JP3122963B2 (ja) 1995-02-10 2001-01-09 株式会社林原生物化学研究所 モノクローナル抗体
JP2952750B2 (ja) 1995-02-23 1999-09-27 株式会社林原生物化学研究所 モノクローナル抗体
JP2724987B2 (ja) 1994-11-15 1998-03-09 株式会社林原生物化学研究所 インターフェロン−γの産生を誘導するポリペプチド
TW581771B (en) * 1994-11-15 2004-04-01 Hayashibara Biochem Lab Recombinant production of a polypeptide for inducing interferon-gamma production, and monoclonal antibody against the polypeptide
JPH08207189A (ja) 1995-02-03 1996-08-13 Toppan Printing Co Ltd 内装用化粧シートおよびその製造方法
US5776731A (en) * 1996-02-21 1998-07-07 Immunex Corporation DNA encoding type-I interleukin-I receptor-like protein designated 2F1
JP2000511418A (ja) * 1996-05-20 2000-09-05 シェーリング コーポレイション ヒトインターロイキン―１ｊおよびそのアンタゴニスト
FR2882746B1 (fr) 2005-03-01 2007-04-27 Commissariat Energie Atomique Procede de preparation d'une solution sol-gel et utilisation de cette solution pour constituer un revetement pour proteger un substrat a surface metallique
US7865223B1 (en) 2005-03-14 2011-01-04 Peter Bernreuter In vivo blood spectrometry
WO2007067178A1 (en) 2005-12-09 2007-06-14 The Gates Corporation Auxiliary power system for a motor vehicle
US7645909B2 (en) 2006-08-10 2010-01-12 Cognis Ip Management Gmbh Linear and branched alcohol ethoxylates for controlling insects
DE102006038439A1 (de) 2006-08-16 2008-02-21 Dürr GmbH & Co. KG Luft- und Prozessortechnik Anlage zur Erzeugung eines an einer vorgegebenen Komponente angereicherten Nutzgases

Similar Documents

Publication Publication Date Title
US20090286855A1 (en) Interleukin-18 mutants, their production and use
DE69635899D1 (de) Polypeptid, das die differenzierung unterdrueckt
CA2230033A1 (en) Production of infectious respiratory syncytial virus from cloned nucleotide sequences
RU2006105498A (ru) Полипептиды для индукции защитного иммунного ответа против staphylococcus aureus
JP2004534503A5 (enExample)
KR19980042925A (ko) 폴리펩티드
JP2002533125A5 (enExample)
AU7617796A (en) Variants of human recombinant interferon-gamma (rhu-ifn-gamma) having increased heat-stability
JP2002522508A5 (enExample)
JPH09289896A5 (enExample)
US5218093A (en) EGF variants and pharmaceutical use thereof
CA2266421A1 (en) Genes coding for a protein having glycoside transfer activity
WO1991016434A3 (en) Bacillus thuringiensis cryif and cryix genes and proteins toxic to lepidopteran insects
CA2576069A1 (en) Detoxifizyme with activity of transforming aflatoxin and the gene encodes thereof
EP0414355A1 (en) Feline interferon and process for production thereof by a silkworm virus vector
ATE287952T1 (de) Humanes thymosin beta 15 gen,protein und dessen verwendungen
DE60336353D1 (de) Rekombinantes protein mit krebsunterdrückender wirkung, sein codierendes gen und seine verwendung
ATE357526T1 (de) Modifizierte hcv peptid-impfstoffe
JP2002345468A5 (enExample)
EP0342173A3 (en) Fibronectin binding protein as well as its preparation
ATE277182T1 (de) Das nuca protein von haemophilus influenzae und dessen kodierender gen
DE60132571D1 (de) Für den menschlichen vanilloid-rezeptor vr3 kodierende dns
MY104405A (en) Structural gene comprising dna coding for an endotoxin protein having toxic activity against insects.
JP2002538775A5 (enExample)
AU701101B2 (en) A novel toxin and a method of producing a toxin