JPH08506175A - タグでコードされる複合体の組合せ化学ライブラリー - Google Patents
タグでコードされる複合体の組合せ化学ライブラリーInfo
- Publication number
- JPH08506175A JPH08506175A JP6509330A JP50933094A JPH08506175A JP H08506175 A JPH08506175 A JP H08506175A JP 6509330 A JP6509330 A JP 6509330A JP 50933094 A JP50933094 A JP 50933094A JP H08506175 A JPH08506175 A JP H08506175A
- Authority
- JP
- Japan
- Prior art keywords
- compound
- identifying
- groups
- group
- library
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/531—Production of immunochemical test materials
- G01N33/532—Production of labelled immunochemicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
- C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
- C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
- C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
- C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
- C07D243/24—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
- C07H21/02—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with ribosyl as saccharide radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
- C07K1/047—Simultaneous synthesis of different peptide species; Peptide libraries
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/0054—Means for coding or tagging the apparatus or the reagents
- B01J2219/00572—Chemical means
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/11—Compounds covalently bound to a solid support
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B70/00—Tags or labels specially adapted for combinatorial chemistry or libraries, e.g. fluorescent tags or bar codes
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Analytical Chemistry (AREA)
- Zoology (AREA)
- Biomedical Technology (AREA)
- Biophysics (AREA)
- Hematology (AREA)
- Microbiology (AREA)
- Urology & Nephrology (AREA)
- Wood Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Physics & Mathematics (AREA)
- Veterinary Medicine (AREA)
- Food Science & Technology (AREA)
- Cell Biology (AREA)
- Pathology (AREA)
- General Engineering & Computer Science (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Inks, Pencil-Leads, Or Crayons (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Record Information Processing For Printing (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Steroid Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US95537192A | 1992-10-01 | 1992-10-01 | |
US1394893A | 1993-02-04 | 1993-02-04 | |
US07/955,371 | 1993-02-04 | ||
US08/013,948 | 1993-02-04 | ||
PCT/US1993/009345 WO1994008051A1 (fr) | 1992-10-01 | 1993-10-01 | Banques chimiques combinatoires complexes codees avec des etiquettes |
Publications (1)
Publication Number | Publication Date |
---|---|
JPH08506175A true JPH08506175A (ja) | 1996-07-02 |
Family
ID=26685452
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP6509330A Ceased JPH08506175A (ja) | 1992-10-01 | 1993-10-01 | タグでコードされる複合体の組合せ化学ライブラリー |
Country Status (14)
Country | Link |
---|---|
EP (1) | EP0665897B1 (fr) |
JP (1) | JPH08506175A (fr) |
KR (1) | KR100310939B1 (fr) |
AT (1) | ATE244769T1 (fr) |
AU (1) | AU686579B2 (fr) |
CA (1) | CA2143848C (fr) |
DE (1) | DE69333087T2 (fr) |
DK (1) | DK0665897T3 (fr) |
ES (1) | ES2204910T3 (fr) |
HU (1) | HUT72495A (fr) |
IL (1) | IL107166A (fr) |
NO (1) | NO951230D0 (fr) |
PT (1) | PT665897E (fr) |
WO (1) | WO1994008051A1 (fr) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2007515419A (ja) * | 2003-12-20 | 2007-06-14 | メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフトング | 2−(ヘテロ)アリール置換テトラヒドロキノリン誘導体 |
Families Citing this family (201)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
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CA2118806A1 (fr) * | 1991-09-18 | 1993-04-01 | William J. Dower | Methode pour la synthese de diverses series d'oligomeres |
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US5840485A (en) * | 1993-05-27 | 1998-11-24 | Selectide Corporation | Topologically segregated, encoded solid phase libraries |
DE69432147T2 (de) * | 1993-05-27 | 2003-11-27 | Selectide Corp | Topologisch getrennte kodierende festphasen-bibliotheken |
US5837689A (en) * | 1993-06-16 | 1998-11-17 | Glycomed Incorporated | Sialyl lewis-x mimetics containing naphthyl backbones |
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US6087186A (en) * | 1993-07-16 | 2000-07-11 | Irori | Methods and apparatus for synthesizing labeled combinatorial chemistry libraries |
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US6184389B1 (en) | 1994-01-11 | 2001-02-06 | Isis Pharmaceuticals, Inc. | Combinatorial libraries having aminodiol monomer subunits |
US6828427B1 (en) | 1994-01-11 | 2004-12-07 | Isis Pharmaceuticals, Inc. | Oligomeric aminodiol-containing compounds, libraries thereof, and process of preparing the same |
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US5856083A (en) * | 1994-05-06 | 1999-01-05 | Pharmacopeia, Inc. | Lawn assay for compounds that affect enzyme activity or bind to target molecules |
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US5604097A (en) * | 1994-10-13 | 1997-02-18 | Spectragen, Inc. | Methods for sorting polynucleotides using oligonucleotide tags |
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CA2210349A1 (fr) * | 1995-01-20 | 1996-07-25 | Molecumetics, Ltd | Bibliotheque de substances mimetiques de retournement astreintes a une conformation et procedes associes |
GB9502225D0 (en) * | 1995-02-04 | 1995-03-22 | Zeneca Ltd | Method |
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US5801175A (en) | 1995-04-07 | 1998-09-01 | Schering Corporation | Tricyclic compounds useful for inhibition of G-protein function and for treatment of proliferative diseases |
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US5925562A (en) * | 1995-04-25 | 1999-07-20 | Irori | Remotely programmable matrices with memories |
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JP2007515419A (ja) * | 2003-12-20 | 2007-06-14 | メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフトング | 2−(ヘテロ)アリール置換テトラヒドロキノリン誘導体 |
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AU686579B2 (en) | 1998-02-12 |
EP0665897B1 (fr) | 2003-07-09 |
HUT72495A (en) | 1996-05-28 |
CA2143848A1 (fr) | 1994-04-14 |
CA2143848C (fr) | 2007-09-11 |
PT665897E (pt) | 2003-11-28 |
DE69333087D1 (de) | 2003-08-14 |
EP0665897A4 (fr) | 1995-09-27 |
KR950703657A (ko) | 1995-09-20 |
AU5536994A (en) | 1994-04-26 |
WO1994008051A1 (fr) | 1994-04-14 |
NO951230L (no) | 1995-03-30 |
EP0665897A1 (fr) | 1995-08-09 |
KR100310939B1 (ko) | 2002-06-20 |
HU9500952D0 (en) | 1995-05-29 |
ES2204910T3 (es) | 2004-05-01 |
NO951230D0 (no) | 1995-03-30 |
DK0665897T3 (da) | 2003-10-20 |
IL107166A0 (en) | 1994-01-25 |
IL107166A (en) | 2000-10-31 |
DE69333087T2 (de) | 2004-05-06 |
ATE244769T1 (de) | 2003-07-15 |
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Free format text: JAPANESE INTERMEDIATE CODE: A313 Effective date: 20060731 |
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A02 | Decision of refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A02 Effective date: 20060905 |