ATE459367T1 - Methoden und verbindungen zur hemmung immunoglobulin-vermittelter reperfusions- verletzungen - Google Patents

Methoden und verbindungen zur hemmung immunoglobulin-vermittelter reperfusions- verletzungen

Info

Publication number
ATE459367T1
ATE459367T1 AT01942082T AT01942082T ATE459367T1 AT E459367 T1 ATE459367 T1 AT E459367T1 AT 01942082 T AT01942082 T AT 01942082T AT 01942082 T AT01942082 T AT 01942082T AT E459367 T1 ATE459367 T1 AT E459367T1
Authority
AT
Austria
Prior art keywords
methods
compounds
reperfusion injury
immunoglobulin
mediated reperfusion
Prior art date
Application number
AT01942082T
Other languages
English (en)
Inventor
Michael C Carroll
Francis D Moore Jr
Herbert B Hechtman
Original Assignee
Immune Disease Inst Inc
Harvard College
Brigham & Womens Hospital
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Immune Disease Inst Inc, Harvard College, Brigham & Womens Hospital filed Critical Immune Disease Inst Inc
Application granted granted Critical
Publication of ATE459367T1 publication Critical patent/ATE459367T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52—Constant or Fc region; Isotype

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Cardiology (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AT01942082T 2000-06-08 2001-06-08 Methoden und verbindungen zur hemmung immunoglobulin-vermittelter reperfusions- verletzungen ATE459367T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US21027200P 2000-06-08 2000-06-08
PCT/US2001/018510 WO2001093892A1 (en) 2000-06-08 2001-06-08 Methods and compositions for inhibiting immunoglobulin-mediated__reperfusion injury

Publications (1)

Publication Number Publication Date
ATE459367T1 true ATE459367T1 (de) 2010-03-15

Family

ID=22782260

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01942082T ATE459367T1 (de) 2000-06-08 2001-06-08 Methoden und verbindungen zur hemmung immunoglobulin-vermittelter reperfusions- verletzungen

Country Status (9)

Country Link
EP (2) EP1286682B1 (de)
JP (1) JP2004502412A (de)
CN (1) CN1443074A (de)
AT (1) ATE459367T1 (de)
AU (1) AU2001275378A1 (de)
CA (1) CA2410458A1 (de)
DE (1) DE60141463D1 (de)
ES (1) ES2343351T3 (de)
WO (1) WO2001093892A1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2560066A1 (en) * 2004-03-01 2005-09-15 The Cbr Institute For Biomedical Research, Inc. Natural igm antibodies and inhibitors thereof
AU2012200909B2 (en) * 2004-03-01 2013-10-03 Immune Disease Institute, Inc Natural lgM antibodies and inhibitors thereof
US20100136684A1 (en) * 2004-03-01 2010-06-03 Carroll Michael C Natural IgM Antibodies
WO2009035055A1 (ja) * 2007-09-14 2009-03-19 Juridical Foundation The Chemo-Sero-Therapeutic Research Institute インスリン様成長因子-１（ｉｇｆ－１）産生促進剤

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* Cited by examiner, † Cited by third party
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JPS6147500A (ja) 1984-08-15 1986-03-07 Res Dev Corp Of Japan キメラモノクロ−ナル抗体及びその製造法
EP0173494A3 (de) 1984-08-27 1987-11-25 The Board Of Trustees Of The Leland Stanford Junior University Chimäre Rezeptoren durch Verbindung und Expression von DNS
GB8422238D0 (en) 1984-09-03 1984-10-10 Neuberger M S Chimeric proteins
JPS61134325A (ja) 1984-12-04 1986-06-21 Teijin Ltd ハイブリツド抗体遺伝子の発現方法
US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
GB8607679D0 (en) 1986-03-27 1986-04-30 Winter G P Recombinant dna product
US5225539A (en) 1986-03-27 1993-07-06 Medical Research Council Recombinant altered antibodies and methods of making altered antibodies
US5223409A (en) 1988-09-02 1993-06-29 Protein Engineering Corp. Directed evolution of novel binding proteins
EP0768377A1 (de) 1988-09-02 1997-04-16 Protein Engineering Corporation Herstellung und Auswahl von Rekombinantproteinen mit verschiedenen Bindestellen
US5530101A (en) 1988-12-28 1996-06-25 Protein Design Labs, Inc. Humanized immunoglobulins
WO1991000906A1 (en) 1989-07-12 1991-01-24 Genetics Institute, Inc. Chimeric and transgenic animals capable of producing human antibodies
WO1991007087A1 (en) 1989-11-13 1991-05-30 Affymax Technologies N.V. Spatially-addressable immobilization of anti-ligands on surfaces
ES2284161T3 (es) 1990-01-12 2007-11-01 Amgen Fremont Inc. Generacion de anticuerpos xenogenicos.
US5427908A (en) 1990-05-01 1995-06-27 Affymax Technologies N.V. Recombinant library screening methods
CA2109602C (en) 1990-07-10 2002-10-01 Gregory P. Winter Methods for producing members of specific binding pairs
GB9015198D0 (en) 1990-07-10 1990-08-29 Brien Caroline J O Binding substance
AU8507191A (en) 1990-08-29 1992-03-30 Genpharm International, Inc. Transgenic non-human animals capable of producing heterologous antibodies
DE69133557D1 (de) 1990-08-29 2007-03-15 Pharming Intellectual Pty Bv Homologe rekombination in säugetier-zellen
ES2113940T3 (es) 1990-12-03 1998-05-16 Genentech Inc Metodo de enriquecimiento para variantes de proteinas con propiedades de union alteradas.
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DE69233769D1 (de) 1991-03-01 2009-09-24 Dyax Corp Chimäres Protein mit Mikroprotein mit zwei oder mehr Disulfidbindungen und Ausgestaltungen davon
AU662148B2 (en) 1991-04-10 1995-08-24 Scripps Research Institute, The Heterodimeric receptor libraries using phagemids
DE4122599C2 (de) 1991-07-08 1993-11-11 Deutsches Krebsforsch Phagemid zum Screenen von Antikörpern
US5677195A (en) 1991-11-22 1997-10-14 Affymax Technologies N.V. Combinatorial strategies for polymer synthesis
US5233409A (en) 1992-02-25 1993-08-03 Schwab Karl W Color analysis of organic constituents in sedimentary rocks for thermal maturity
US5359115A (en) 1992-03-26 1994-10-25 Affymax Technologies, N.V. Methods for the synthesis of phosphonate esters
US5573905A (en) 1992-03-30 1996-11-12 The Scripps Research Institute Encoded combinatorial chemical libraries
US5288514A (en) 1992-09-14 1994-02-22 The Regents Of The University Of California Solid phase and combinatorial synthesis of benzodiazepine compounds on a solid support
EP0665897B1 (de) 1992-10-01 2003-07-09 The Trustees Of Columbia University In The City Of New York Komplexe kombinatorische chemische banken, die mit markierungen versehen sind
JPH08511420A (ja) 1993-06-16 1996-12-03 セルテック・セラピューテイクス・リミテッド 抗 体
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IT1395574B1 (it) 2009-09-14 2012-10-16 Guala Dispensing Spa Dispositivo di erogazione

Also Published As

Publication number Publication date
EP1286682A1 (de) 2003-03-05
CN1443074A (zh) 2003-09-17
DE60141463D1 (de) 2010-04-15
ES2343351T3 (es) 2010-07-29
WO2001093892A1 (en) 2001-12-13
JP2004502412A (ja) 2004-01-29
EP1286682B1 (de) 2010-03-03
AU2001275378A1 (en) 2001-12-17
CA2410458A1 (en) 2001-12-13
EP1286682A4 (de) 2004-10-13
EP2251026A1 (de) 2010-11-17

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