JPH06506112A - 細胞質顆粒構成成分のインビトロ診断のための手段及びその生物学的応用 - Google Patents

細胞質顆粒構成成分のインビトロ診断のための手段及びその生物学的応用

Info

Publication number
JPH06506112A
JPH06506112A JP4508582A JP50858292A JPH06506112A JP H06506112 A JPH06506112 A JP H06506112A JP 4508582 A JP4508582 A JP 4508582A JP 50858292 A JP50858292 A JP 50858292A JP H06506112 A JPH06506112 A JP H06506112A
Authority
JP
Japan
Prior art keywords
cells
granzyme
antibody
perforin
antibodies
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP4508582A
Other languages
English (en)
Japanese (ja)
Inventor
サスポルテ，マリリーヌ
チョップ，ヨルク
Original Assignee
アンスティテュ ナショナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシュ メディカル
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by アンスティテュ ナショナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシュ メディカル filed Critical アンスティテュ ナショナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシュ メディカル
Publication of JPH06506112A publication Critical patent/JPH06506112A/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6467—Granzymes, e.g. granzyme A (3.4.21.78); granzyme B (3.4.21.79)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against enzymes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
JP4508582A 1991-03-14 1992-03-16 細胞質顆粒構成成分のインビトロ診断のための手段及びその生物学的応用 Pending JPH06506112A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR9103108A FR2673952A1 (fr) 1991-03-14 1991-03-14 Moyens pour le diagnostic in vitro de constituants de granules cytoplasmiques et applications biologiques.
FR91/03108 1991-03-14
PCT/FR1992/000240 WO1992016644A1 (fr) 1991-03-14 1992-03-16 Moyens pour le diagnostic in vitro de constituants de granules cytoplasmiques et applications biologiques

Publications (1)

Publication Number Publication Date
JPH06506112A true JPH06506112A (ja) 1994-07-14

Family

ID=9410734

Family Applications (1)

Application Number Title Priority Date Filing Date
JP4508582A Pending JPH06506112A (ja) 1991-03-14 1992-03-16 細胞質顆粒構成成分のインビトロ診断のための手段及びその生物学的応用

Country Status (5)

Country Link
EP (1) EP0575539A1 (enExample)
JP (1) JPH06506112A (enExample)
CA (1) CA2106193A1 (enExample)
FR (1) FR2673952A1 (enExample)
WO (1) WO1992016644A1 (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2887060B2 (ja) * 1993-06-30 1999-04-26 日清製粉株式会社 グリセンチンの生産方法
US5858758A (en) * 1997-05-07 1999-01-12 Incyte Pharmaceuticals, Inc. Human serine protease precursor

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4783410A (en) * 1985-06-28 1988-11-08 Massachusetts Institute Of Technology Cytotoxic t lymphocyte serine esterase and method for stimulation and inhibition
EP0245051B1 (en) * 1986-05-06 1992-08-12 The Board Of Trustees Of The Leland Stanford Junior University Killer cell cytotoxic composition

Also Published As

Publication number Publication date
FR2673952A1 (fr) 1992-09-18
FR2673952B1 (enExample) 1995-05-12
CA2106193A1 (fr) 1992-09-15
EP0575539A1 (fr) 1993-12-29
WO1992016644A1 (fr) 1992-10-01

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