JPH06504702A - 生体再吸収性材料および医療用途のために該材料から製造された製品 - Google Patents
生体再吸収性材料および医療用途のために該材料から製造された製品Info
- Publication number
- JPH06504702A JPH06504702A JP4506123A JP50612392A JPH06504702A JP H06504702 A JPH06504702 A JP H06504702A JP 4506123 A JP4506123 A JP 4506123A JP 50612392 A JP50612392 A JP 50612392A JP H06504702 A JPH06504702 A JP H06504702A
- Authority
- JP
- Japan
- Prior art keywords
- plasticizer
- weight
- polymer
- polymers
- bioresorbable
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L31/141—Plasticizers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/18—Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/502—Plasticizers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/04—Macromolecular materials
- A61L31/06—Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
Abstract
Description
Claims (22)
- 1.生体再吸収性ポリマーまたは生体再吸収性ポリマー類が、グリコール酸、乳 酸、カプロラクトン、炭酸トリメチレン、パラジオキサノンおよび1,5−ジオ キセパン−2−オンを含むモノマーの群から選択されるホモポリマー、コポリマ ーまたはその混合物からなり、可塑剤が、アセチル化または非アセチル化クエン 酸のエチル、ブチルおよびヘキシルエステル、2単位以上10単位以下の乳酸の エチル末端化オリゴマー、グリセロールの乳酸エステルを含むモノマーの群から 選択され、材料が、実質的に記憶力を有しないで該材料に可塑的展性を与えるた めに少なくとも50%の非晶質ポリマーまたはポリマー類からなることを特徴と する、生体再吸収性ポリマーまたは生体再吸収性ポリマー類および可塑剤の組成 物からなる医療用生体再吸収性材料。
- 2.可塑剤の量が実質的に5重量%〜実質的に25重量%の範囲である請求項1 記載の生体再吸収性材料。
- 3.ポリマーがポリ乳酸に基づき、可塑剤がクエン酸エステルに基づき、可塑剤 の割合が実質的に9重量%〜実質的に17重量%の範囲である請求項2記載の生 体再吸収性材料。
- 4.ポリマーがポリ乳酸に基づき、可塑剤がエチル末端化乳酸オリゴマーに基づ き、可塑剤が約2.0重量%までの量である請求項2記載の生体再吸収性材料。
- 5.ポリマーとして実質的に76重量%のポリ−d,1−ラクチドおよび10重 量%のポリ−1−ラクチド、ならびに可塑剤として14重量%のATBCからな る請求項2記載の生体再吸収性材料。
- 6.ポリマーとして実質的に75重量%のポリ−d,1−ラクチドおよび10重 量%のポリカプロラクトン、ならびに可塑剤として15重量%のATBCからな る請求項2記載の生体再吸収性材料。
- 7.ポリマーとして実質的に80重量%のポリ−d,1−ラクチド、および可塑 剤として20重量%の乳酸のエチル末端化オリゴマーからなる請求項2記載の生 体再吸収性材料。
- 8.ポリマーまたはポリマー類が多少の結晶性ポリマーを含む請求項1記載の生 体再吸収性材料。
- 9.結晶性ポリマーが5〜40重量%の範囲である請求項5記載の生体再吸収性 材料。
- 10.生体再吸収性ポリマーまたは生体再吸収性ポリマー類が、グリコール酸、 乳酸、カプロラクトン、炭酸トリメチレン、パラジオキサノンおよび1,5−ジ オキセパン−2−オンを含むモノマーの群から選択されるホモポリマー、コポリ マーまたはその混合物からなり、可塑剤が、アセチル化または非アセチル化クエ ン酸のエチル、ブチルおよびヘキシルエステル、2単位以上10単位以下の乳酸 のエチル末端化オリゴマー、グリセロールの乳酸エステルを含むモノマーの群か ら選択され、材料が、実質的に記憶力を有しないで該材料に可塑的展性を与える ために少なくとも50%の非晶質ポリマーまたはポリマー類からなることを特徴 とする、生体再吸収性ポリマーまたは生体再吸収性ポリマー類の組成物および可 塑剤からなる医療用製品。
- 11.可塑剤の量が実質的に5重量%〜実質的に25重量%の範囲である請求項 10記載の製品。
- 12.ポリマーがポリ乳酸に基づき、可塑剤がクエン酸エステルに基づき、可塑 剤の割合が実質的に9重量%〜実質的に17重量%の範囲である請求項11記載 の製品。
- 13.ポリマーがポリ乳酸に基づき、可塑剤がエチル末端化乳酸オリゴマーに基 づき、可塑剤が約20重量%までの量である請求項11記載の製品。
- 14.ポリマーとして実質的に76重量%のポリ−d,1−ラクチドおよび10 重量%のポリ−1−ラクチド、ならびに可塑剤として14重量%のATBCから なる請求項11記載の製品。
- 15.ポリマーとして実質的に75重量%のポリ−d,1−ラクチドおよび10 重量%のポリカプロラクトン、ならびに可塑剤として15重量%のATBCから なる請求項11記載の製品。
- 16.ポリマーとして実質的に80重量%のポリ−d,1−ラクチド、および可 塑剤として20重量%の乳酸のエチル末端化オリゴマーからなる請求項11記載 の製品。
- 17.ポリマーまたはポリマー類が多少の結晶性ポリマーを含む請求項10記載 の製品。
- 18.結晶性ポリマーが5〜40重量%の範囲である請求項14記載の製品。
- 19.製品が有孔素子からなる請求項10記載の製品。
- 20.穿孔の開口部が最小横断寸法10μmを有する請求項19記載の製品。
- 21.合計開口面積が少なくとも6%である請求項19または20記載の製品。
- 22.開口の中心間距離が実質的に700μm〜実質的に150μmの範囲離間 している請求項19〜21のいずれか1項記載の製品。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE9100610-6 | 1991-03-04 | ||
SE9100610A SE9100610D0 (sv) | 1991-03-04 | 1991-03-04 | Bioresorbable material for medical use |
PCT/SE1992/000139 WO1992015340A1 (en) | 1991-03-04 | 1992-03-04 | Bioresorbable material and an article of manufacture made of such material for medical use |
Publications (2)
Publication Number | Publication Date |
---|---|
JPH06504702A true JPH06504702A (ja) | 1994-06-02 |
JP3475360B2 JP3475360B2 (ja) | 2003-12-08 |
Family
ID=20382033
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP50612392A Expired - Lifetime JP3475360B2 (ja) | 1991-03-04 | 1992-03-04 | 生体再吸収性材料および医療用途のために該材料から製造された製品 |
Country Status (9)
Country | Link |
---|---|
US (1) | US5525646A (ja) |
EP (1) | EP0574474B1 (ja) |
JP (1) | JP3475360B2 (ja) |
AT (1) | ATE168889T1 (ja) |
CA (1) | CA2103541A1 (ja) |
DE (1) | DE69226429T2 (ja) |
NO (1) | NO302154B1 (ja) |
SE (1) | SE9100610D0 (ja) |
WO (1) | WO1992015340A1 (ja) |
Cited By (4)
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WO2007063820A1 (ja) | 2005-12-02 | 2007-06-07 | Sunstar Suisse Sa | エレクトロスピニング法により形成された生体適合性のナノ又はマイクロファイバー不織布を有する生体適合材、及びその製造方法 |
WO2007083797A1 (ja) * | 2006-01-23 | 2007-07-26 | Terumo Kabushiki Kaisha | ステント |
JP2011136181A (ja) * | 1997-10-02 | 2011-07-14 | Gore Enterprise Holdings Inc | 自己凝集性の連続フィラメントの不織ウェブ |
JP2018509243A (ja) * | 2015-03-25 | 2018-04-05 | エシコン エルエルシーEthicon LLC | 外科用ステープラにステープル支持具を取り外し可能に取り付けるための展性生体吸収性ポリマー接着剤 |
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1991
- 1991-03-04 SE SE9100610A patent/SE9100610D0/xx unknown
-
1992
- 1992-03-04 DE DE69226429T patent/DE69226429T2/de not_active Expired - Lifetime
- 1992-03-04 CA CA002103541A patent/CA2103541A1/en not_active Abandoned
- 1992-03-04 AT AT92906037T patent/ATE168889T1/de not_active IP Right Cessation
- 1992-03-04 WO PCT/SE1992/000139 patent/WO1992015340A1/en active IP Right Grant
- 1992-03-04 US US08/108,688 patent/US5525646A/en not_active Expired - Lifetime
- 1992-03-04 EP EP92906037A patent/EP0574474B1/en not_active Expired - Lifetime
- 1992-03-04 JP JP50612392A patent/JP3475360B2/ja not_active Expired - Lifetime
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1993
- 1993-09-03 NO NO933139A patent/NO302154B1/no unknown
Cited By (5)
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JP2011136181A (ja) * | 1997-10-02 | 2011-07-14 | Gore Enterprise Holdings Inc | 自己凝集性の連続フィラメントの不織ウェブ |
WO2007063820A1 (ja) | 2005-12-02 | 2007-06-07 | Sunstar Suisse Sa | エレクトロスピニング法により形成された生体適合性のナノ又はマイクロファイバー不織布を有する生体適合材、及びその製造方法 |
WO2007083797A1 (ja) * | 2006-01-23 | 2007-07-26 | Terumo Kabushiki Kaisha | ステント |
JPWO2007083797A1 (ja) * | 2006-01-23 | 2009-06-18 | テルモ株式会社 | ステント |
JP2018509243A (ja) * | 2015-03-25 | 2018-04-05 | エシコン エルエルシーEthicon LLC | 外科用ステープラにステープル支持具を取り外し可能に取り付けるための展性生体吸収性ポリマー接着剤 |
Also Published As
Publication number | Publication date |
---|---|
SE9100610D0 (sv) | 1991-03-04 |
DE69226429T2 (de) | 1999-04-01 |
JP3475360B2 (ja) | 2003-12-08 |
EP0574474B1 (en) | 1998-07-29 |
CA2103541A1 (en) | 1992-09-05 |
ATE168889T1 (de) | 1998-08-15 |
US5525646A (en) | 1996-06-11 |
NO933139L (no) | 1993-11-03 |
NO302154B1 (no) | 1998-02-02 |
WO1992015340A1 (en) | 1992-09-17 |
DE69226429D1 (de) | 1998-09-03 |
EP0574474A1 (en) | 1993-12-22 |
EP0574474A4 (en) | 1993-12-13 |
NO933139D0 (no) | 1993-09-03 |
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