JPH0567634B2 - - Google Patents

Info

Publication number
JPH0567634B2
JPH0567634B2 JP89160561A JP16056189A JPH0567634B2 JP H0567634 B2 JPH0567634 B2 JP H0567634B2 JP 89160561 A JP89160561 A JP 89160561A JP 16056189 A JP16056189 A JP 16056189A JP H0567634 B2 JPH0567634 B2 JP H0567634B2
Authority
JP
Japan
Prior art keywords
formula
solvent
compound
group
reaction
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP89160561A
Other languages
English (en)
Japanese (ja)
Other versions
JPH02124884A (ja
Inventor
Gun Tao Riu
Ryan Hoan
Aa Chan Rao
Jin Juo
Ien Rii
Katsuo Hatayama
Tatsuhiko Sano
Yoshinari Yoshikawa
Shohei Higuchi
Iwao Arai
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Taisho Pharmaceutical Co Ltd
Original Assignee
Taisho Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Taisho Pharmaceutical Co Ltd filed Critical Taisho Pharmaceutical Co Ltd
Publication of JPH02124884A publication Critical patent/JPH02124884A/ja
Publication of JPH0567634B2 publication Critical patent/JPH0567634B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/50—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
    • C07D317/58—Radicals substituted by nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
JP1160561A 1988-07-08 1989-06-22 Ｎ―置換アミド誘導体 Granted JPH02124884A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP63-170727 1988-07-08
JP17072788 1988-07-08

Publications (2)

Publication Number Publication Date
JPH02124884A JPH02124884A (ja) 1990-05-14
JPH0567634B2 true JPH0567634B2 (en, 2012) 1993-09-27

Family

ID=15910274

Family Applications (1)

Application Number Title Priority Date Filing Date
JP1160561A Granted JPH02124884A (ja) 1988-07-08 1989-06-22 Ｎ―置換アミド誘導体

Country Status (7)

Country Link
US (1) US4937360A (en, 2012)
EP (1) EP0350251B1 (en, 2012)
JP (1) JPH02124884A (en, 2012)
KR (1) KR970002232B1 (en, 2012)
AT (1) ATE102937T1 (en, 2012)
CA (1) CA1328875C (en, 2012)
DE (1) DE68913835T2 (en, 2012)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH05310678A (ja) * 1990-01-22 1993-11-22 Mitsubishi Kasei Corp １−フェニルアルキル−３−フェニル尿素誘導体
JP4374082B2 (ja) * 1992-07-24 2009-12-02 ザ リージェンツ オブ ザ ユニバーシティー オブ カリフォルニア Ａｍｐａ受容体によって仲介されるシナプス応答性を高める薬物
US5426225A (en) * 1993-12-30 1995-06-20 American Cyanamid Company Perfluoroalkanoyl aminonitriles
MY119161A (en) * 1994-04-18 2005-04-30 Novartis Ag Delta-amino-gamma-hydroxy-omega-aryl-alkanoic acid amides with enzyme especially renin inhibiting activities
US5852008A (en) * 1995-01-24 1998-12-22 The Regents Of The University Of California Heteroatom substituted benzoyl derivatives that enhance synaptic response mediated by receptors
KR100345204B1 (ko) * 2000-03-21 2002-07-24 현대자동차주식회사 리벳 삽입 장치
KR100345203B1 (ko) * 2000-03-21 2002-07-24 현대자동차주식회사 리벳팅 장치
KR20180057162A (ko) * 2016-11-22 2018-05-30 맥스엔지니어링(주) 면적차에 의해 연속 작동되는 피스톤과 절환 밸브가 내장된 선형 유체 펌프
WO2023034510A1 (en) 2021-09-01 2023-03-09 ATAI Life Sciences AG Synthesis of mdma or its optically active ( r)- or ( s)-mdma isomers
US11845736B2 (en) 2021-10-01 2023-12-19 Empathbio, Inc. Prodrugs of MDMA, MDA, and derivatives thereof
WO2023129958A2 (en) * 2021-12-28 2023-07-06 ATAI Life Sciences AG Nitric oxide releasing prodrugs of mda and mdma

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE332474C (de) * 1912-12-24 1921-02-01 Chem Fab Verfahren zur Darstellung von N-Alkyl-Acyl-Homopiperonylaminen
DE1543372A1 (de) * 1966-10-18 1971-04-01 Boehringer Sohn Ingelheim Verfahren zur Herstellung von o-substituierten 3,4-Dioxyphenylalkanolaminen
US4147799A (en) * 1971-06-24 1979-04-03 Kyowa Hakko Kogyo Co., Ltd. Process for reducing blood pressure and blocking β-adrenergic receptor
US4684651A (en) * 1981-03-17 1987-08-04 Mitsubishi Chemical Industries Limited Alkylenedioxybenzene and acid addition salts thereof useful as hypotensives
ES8203876A1 (es) * 1981-05-13 1982-04-01 Ferrer Int Procedimiento de obtencion de nuevos a-amino derivados ci- clicos del 1-(3',4'-metilendioxifenil)etanol
CH664565A5 (de) * 1985-05-09 1988-03-15 Ciba Geigy Ag Mittel zum schuetzen von kulturpflanzen vor der phytotoxischen wirkung von herbizid wirksamen chloracetaniliden.

Also Published As

Publication number Publication date
DE68913835T2 (de) 1994-06-30
EP0350251B1 (en) 1994-03-16
ATE102937T1 (de) 1994-04-15
EP0350251A2 (en) 1990-01-10
KR970002232B1 (ko) 1997-02-26
CA1328875C (en) 1994-04-26
JPH02124884A (ja) 1990-05-14
US4937360A (en) 1990-06-26
EP0350251A3 (en) 1990-03-14
KR900001673A (ko) 1990-02-27
DE68913835D1 (de) 1994-04-21

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