KR900001673A - N-치환 아미드 유도체 - Google Patents

N-치환 아미드 유도체 Download PDF

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Publication number
KR900001673A
KR900001673A KR1019890009687A KR890009687A KR900001673A KR 900001673 A KR900001673 A KR 900001673A KR 1019890009687 A KR1019890009687 A KR 1019890009687A KR 890009687 A KR890009687 A KR 890009687A KR 900001673 A KR900001673 A KR 900001673A
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KR
South Korea
Prior art keywords
compound
methylenedioxyphenacyl
substituted amide
amide derivatives
carbon atoms
Prior art date
Application number
KR1019890009687A
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English (en)
Other versions
KR970002232B1 (ko
Inventor
겡타우 리우
리앙 후앙
에르창 라오
진 즈호우
얀 리
가쓰오 하따야마
다쓰히꼬 사노
겐세이 요시까와
쇼헤이 히구찌
이와오 아라이
Original Assignee
우에하라 아끼라
다이쇼 세이야꾸 가부시끼가이샤
후구이센
중화의학과학원
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Application filed by 우에하라 아끼라, 다이쇼 세이야꾸 가부시끼가이샤, 후구이센, 중화의학과학원 filed Critical 우에하라 아끼라
Publication of KR900001673A publication Critical patent/KR900001673A/ko
Application granted granted Critical
Publication of KR970002232B1 publication Critical patent/KR970002232B1/ko

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/50—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
    • C07D317/58—Radicals substituted by nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)

Abstract

내용 없음

Description

N-치환 아미드 유도체
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (7)

  1. 다음의 구조식으로 표시되는 N-치환 아미드.
    식중, A는 -CH(OH)- 또는 -C(=O)- 이고 R1은 수소원자이거나 또는 1 내지 3개의 탄소원자를 갖는 알킬기이고, R2는 1 내지 6개의 탄소원자 갖는 알킬기이다.
  2. 제1항에 있어서, N-(3,4-메틸렌디옥시페나실)아세트아미드인 화합물.
  3. 제1항에 있어서, N-메틸-N-(3,4-메틸렌디옥시페나실)아세트아미드인 화합물.
  4. 제1항에 있어서, N-메틸-N-(3,4-메틸렌디옥시페나실)-n-헥산아미드인 화합물.
  5. 제1항에 있어서, N-(3,4-메틸렌디옥시페나실)-n-부탄아미드인 화합물.
  6. 제1항에 있어서, N-(3,4-메틸렌디옥시페나실)-n-헥산아미드인 화합물.
  7. 제1항에 있어서, N-메틸-N-(β-히드록시-3,4-메틸렌디옥시페네틸)아세트아미드인 화합물.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019890009687A 1988-07-08 1989-07-07 N-치환 아미드 유도체 KR970002232B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP63-170727 1988-07-08
JP17072788 1988-07-08

Publications (2)

Publication Number Publication Date
KR900001673A true KR900001673A (ko) 1990-02-27
KR970002232B1 KR970002232B1 (ko) 1997-02-26

Family

ID=15910274

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019890009687A KR970002232B1 (ko) 1988-07-08 1989-07-07 N-치환 아미드 유도체

Country Status (7)

Country Link
US (1) US4937360A (ko)
EP (1) EP0350251B1 (ko)
JP (1) JPH02124884A (ko)
KR (1) KR970002232B1 (ko)
AT (1) ATE102937T1 (ko)
CA (1) CA1328875C (ko)
DE (1) DE68913835T2 (ko)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100345203B1 (ko) * 2000-03-21 2002-07-24 현대자동차주식회사 리벳팅 장치
KR100345204B1 (ko) * 2000-03-21 2002-07-24 현대자동차주식회사 리벳 삽입 장치

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH05310678A (ja) * 1990-01-22 1993-11-22 Mitsubishi Kasei Corp １−フェニルアルキル−３−フェニル尿素誘導体
CA2450801C (en) * 1992-07-24 2009-11-17 The Regent Of The University Of California Drugs that enhance synaptic responses mediated by ampa receptors
US5426225A (en) * 1993-12-30 1995-06-20 American Cyanamid Company Perfluoroalkanoyl aminonitriles
MY119161A (en) * 1994-04-18 2005-04-30 Novartis Ag Delta-amino-gamma-hydroxy-omega-aryl-alkanoic acid amides with enzyme especially renin inhibiting activities
US5852008A (en) * 1995-01-24 1998-12-22 The Regents Of The University Of California Heteroatom substituted benzoyl derivatives that enhance synaptic response mediated by receptors
KR20180057162A (ko) * 2016-11-22 2018-05-30 맥스엔지니어링(주) 면적차에 의해 연속 작동되는 피스톤과 절환 밸브가 내장된 선형 유체 펌프
WO2023034510A1 (en) 2021-09-01 2023-03-09 ATAI Life Sciences AG Synthesis of mdma or its optically active ( r)- or ( s)-mdma isomers
US11845736B2 (en) 2021-10-01 2023-12-19 Empathbio, Inc. Prodrugs of MDMA, MDA, and derivatives thereof
US11912680B2 (en) 2021-12-28 2024-02-27 Empathbio, Inc. Nitric oxide releasing prodrugs of MDA and MDMA

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE332474C (de) * 1912-12-24 1921-02-01 Chem Fab Verfahren zur Darstellung von N-Alkyl-Acyl-Homopiperonylaminen
DE1543372A1 (de) * 1966-10-18 1971-04-01 Boehringer Sohn Ingelheim Verfahren zur Herstellung von o-substituierten 3,4-Dioxyphenylalkanolaminen
US4147799A (en) * 1971-06-24 1979-04-03 Kyowa Hakko Kogyo Co., Ltd. Process for reducing blood pressure and blocking β-adrenergic receptor
US4684651A (en) * 1981-03-17 1987-08-04 Mitsubishi Chemical Industries Limited Alkylenedioxybenzene and acid addition salts thereof useful as hypotensives
ES8203876A1 (es) * 1981-05-13 1982-04-01 Ferrer Int Procedimiento de obtencion de nuevos a-amino derivados ci- clicos del 1-(3',4'-metilendioxifenil)etanol
CH664565A5 (de) * 1985-05-09 1988-03-15 Ciba Geigy Ag Mittel zum schuetzen von kulturpflanzen vor der phytotoxischen wirkung von herbizid wirksamen chloracetaniliden.

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100345203B1 (ko) * 2000-03-21 2002-07-24 현대자동차주식회사 리벳팅 장치
KR100345204B1 (ko) * 2000-03-21 2002-07-24 현대자동차주식회사 리벳 삽입 장치

Also Published As

Publication number Publication date
DE68913835T2 (de) 1994-06-30
DE68913835D1 (de) 1994-04-21
JPH0567634B2 (ko) 1993-09-27
JPH02124884A (ja) 1990-05-14
EP0350251A2 (en) 1990-01-10
KR970002232B1 (ko) 1997-02-26
EP0350251A3 (en) 1990-03-14
ATE102937T1 (de) 1994-04-15
US4937360A (en) 1990-06-26
EP0350251B1 (en) 1994-03-16
CA1328875C (en) 1994-04-26

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