KR960700245A - 메토트렉세이트 유도체[methotrexate derivative] - Google Patents

메토트렉세이트 유도체[methotrexate derivative]

Info

Publication number
KR960700245A
KR960700245A KR1019950702631A KR19950702631A KR960700245A KR 960700245 A KR960700245 A KR 960700245A KR 1019950702631 A KR1019950702631 A KR 1019950702631A KR 19950702631 A KR19950702631 A KR 19950702631A KR 960700245 A KR960700245 A KR 960700245A
Authority
KR
South Korea
Prior art keywords
methotrexate derivative
general formula
methotrexate
derivative
salt
Prior art date
Application number
KR1019950702631A
Other languages
English (en)
Other versions
KR100259742B1 (ko
Inventor
노부히로 오오이
히로시 스즈끼
Original Assignee
나가야마 오사무
쥬우가이세이야꾸 가부시끼가이샤
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 나가야마 오사무, 쥬우가이세이야꾸 가부시끼가이샤 filed Critical 나가야마 오사무
Publication of KR960700245A publication Critical patent/KR960700245A/ko
Application granted granted Critical
Publication of KR100259742B1 publication Critical patent/KR100259742B1/ko

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D475/00—Heterocyclic compounds containing pteridine ring systems
    • C07D475/06—Heterocyclic compounds containing pteridine ring systems with a nitrogen atom directly attached in position 4
    • C07D475/08—Heterocyclic compounds containing pteridine ring systems with a nitrogen atom directly attached in position 4 with a nitrogen atom directly attached in position 2

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

일반식
(식 중 R1, R2는 같거나 달라도 좋고, 수소원자 또는 탄소수 1~4의 저급 알킬기를나타낸다.)로 표시되는 화합물 및 그의 염, 및 그들의 1종 이상을 유효성분으로서 함유하는 항류머티즘제.

Description

메토트렉세이트 유도체(METHOTREXATE DERIVATIVE)
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (2)

  1. 일반식(Ⅰ)
    (식 중 R1, R2는 같거나 달라도 좋고, 수소원자 또는 탄소수 1~4의 저급 알킬기를나타낸다.)로 표시되는 화합물 및 그의 염
  2. 제1항 기재의 일반식(Ⅰ)으로 표시되는 화합물 및 그의 염 중 1종 이상을 유효성분으로서 함유하는 항류 머티즘제.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019950702631A 1992-12-25 1993-12-24 메토트렉세이트 유도체 KR100259742B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP92-362027 1992-12-25
JP36202792 1992-12-25
PCT/JP1993/001867 WO1994014810A1 (en) 1992-12-25 1993-12-24 Methotrexate derivative

Publications (2)

Publication Number Publication Date
KR960700245A true KR960700245A (ko) 1996-01-19
KR100259742B1 KR100259742B1 (ko) 2000-07-01

Family

ID=18475662

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019950702631A KR100259742B1 (ko) 1992-12-25 1993-12-24 메토트렉세이트 유도체

Country Status (13)

Country Link
US (1) US5728692A (ko)
EP (1) EP0676399B1 (ko)
KR (1) KR100259742B1 (ko)
CN (1) CN1037771C (ko)
AT (1) ATE184605T1 (ko)
AU (1) AU5715894A (ko)
CA (1) CA2152485A1 (ko)
DE (1) DE69326479T2 (ko)
DK (1) DK0676399T3 (ko)
ES (1) ES2140524T3 (ko)
GR (1) GR3031864T3 (ko)
SG (1) SG52733A1 (ko)
WO (1) WO1994014810A1 (ko)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0818199A4 (en) * 1995-03-27 2002-08-14 Chugai Pharmaceutical Co Ltd MEDICINE CONTAINING METHOTREXATE DERIVATIVE
AU1942497A (en) * 1996-03-19 1997-10-10 Chugai Seiyaku Kabushiki Kaisha Uveitis remedy
WO2000000492A1 (fr) * 1998-06-26 2000-01-06 Chugai Seiyaku Kabushiki Kaisha DERIVE D'ACIDE L-α-AMINOADIPIQUE EN POUDRE FINE, PREPARATIONS SOLIDES ORALES CONTENANT LEDIT DERIVE ET PROCEDE DE TRAITEMENT DE POUDRES EN VRAC
AU6594000A (en) * 1999-08-17 2001-03-13 Chugai Seiyaku Kabushiki Kaisha Remedies for myocardial infarction
US20060039985A1 (en) * 2004-04-27 2006-02-23 Bennett David B Methotrexate compositions
US7741317B2 (en) * 2005-10-21 2010-06-22 Bristol-Myers Squibb Company LXR modulators
WO2009114325A2 (en) 2008-03-03 2009-09-17 Tosk, Incorporated Methotrexate adjuvants to reduce toxicity and methods for using the same
EP2527322A1 (en) 2011-05-24 2012-11-28 Noscira, S.A. Carbamyl alkylphenyl disulfide derivatives and their therapeutic uses

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2784670B2 (ja) * 1989-08-09 1998-08-06 株式会社シーエスケイ パチンコ景品交換システム
JPH04368385A (ja) * 1991-06-12 1992-12-21 Chugai Pharmaceut Co Ltd 新規メトトレキセート誘導体
AU8333291A (en) * 1990-08-14 1992-03-17 Chugai Seiyaku Kabushiki Kaisha Novel methotrexate derivative
TW223637B (ko) * 1992-01-27 1994-05-11 Chugai Pharmaceutical Co Ltd
JP3281099B2 (ja) * 1992-02-13 2002-05-13 中外製薬株式会社 抗リウマチ剤

Also Published As

Publication number Publication date
GR3031864T3 (en) 2000-02-29
EP0676399B1 (en) 1999-09-15
WO1994014810A1 (en) 1994-07-07
US5728692A (en) 1998-03-17
DE69326479T2 (de) 2000-03-02
EP0676399A4 (en) 1996-04-17
ES2140524T3 (es) 2000-03-01
DE69326479D1 (de) 1999-10-21
DK0676399T3 (da) 2000-03-20
CN1093365A (zh) 1994-10-12
ATE184605T1 (de) 1999-10-15
CN1037771C (zh) 1998-03-18
EP0676399A1 (en) 1995-10-11
CA2152485A1 (en) 1994-07-07
AU5715894A (en) 1994-07-19
KR100259742B1 (ko) 2000-07-01
SG52733A1 (en) 1998-09-28

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