DE69326479D1 - Methotrexat-derivate - Google Patents

Methotrexat-derivate

Info

Publication number
DE69326479D1
DE69326479D1 DE69326479T DE69326479T DE69326479D1 DE 69326479 D1 DE69326479 D1 DE 69326479D1 DE 69326479 T DE69326479 T DE 69326479T DE 69326479 T DE69326479 T DE 69326479T DE 69326479 D1 DE69326479 D1 DE 69326479D1
Authority
DE
Germany
Prior art keywords
methotrexate derivatives
antirheumatic
chem
alkyl
salt
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69326479T
Other languages
English (en)
Other versions
DE69326479T2 (de
Inventor
Nobuhiro Ohi
Hiroshi Suzuki
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chugai Pharmaceutical Co Ltd
Original Assignee
Chugai Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chugai Pharmaceutical Co Ltd filed Critical Chugai Pharmaceutical Co Ltd
Publication of DE69326479D1 publication Critical patent/DE69326479D1/de
Application granted granted Critical
Publication of DE69326479T2 publication Critical patent/DE69326479T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D475/00—Heterocyclic compounds containing pteridine ring systems
    • C07D475/06—Heterocyclic compounds containing pteridine ring systems with a nitrogen atom directly attached in position 4
    • C07D475/08—Heterocyclic compounds containing pteridine ring systems with a nitrogen atom directly attached in position 4 with a nitrogen atom directly attached in position 2

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DE69326479T 1992-12-25 1993-12-24 Methotrexat-derivate Expired - Fee Related DE69326479T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP36202792 1992-12-25
PCT/JP1993/001867 WO1994014810A1 (en) 1992-12-25 1993-12-24 Methotrexate derivative

Publications (2)

Publication Number Publication Date
DE69326479D1 true DE69326479D1 (de) 1999-10-21
DE69326479T2 DE69326479T2 (de) 2000-03-02

Family

ID=18475662

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69326479T Expired - Fee Related DE69326479T2 (de) 1992-12-25 1993-12-24 Methotrexat-derivate

Country Status (13)

Country Link
US (1) US5728692A (de)
EP (1) EP0676399B1 (de)
KR (1) KR100259742B1 (de)
CN (1) CN1037771C (de)
AT (1) ATE184605T1 (de)
AU (1) AU5715894A (de)
CA (1) CA2152485A1 (de)
DE (1) DE69326479T2 (de)
DK (1) DK0676399T3 (de)
ES (1) ES2140524T3 (de)
GR (1) GR3031864T3 (de)
SG (1) SG52733A1 (de)
WO (1) WO1994014810A1 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100400509B1 (ko) * 1995-03-27 2004-04-03 쥬가이 세이야쿠 가부시키가이샤 메토트렉세이트유도체를함유하는약제
WO1997034606A1 (fr) * 1996-03-19 1997-09-25 Chugai Seiyaku Kabushiki Kaisha Medicament contre l'uveite
AU4531499A (en) * 1998-06-26 2000-01-17 Chugai Seiyaku Kabushiki Kaisha Fine powder of l-alpha-aminoadipic acid derivative, oral solid preparations containing the same, and method for treatment of bulk powders
AU6594000A (en) * 1999-08-17 2001-03-13 Chugai Seiyaku Kabushiki Kaisha Remedies for myocardial infarction
US20060039985A1 (en) * 2004-04-27 2006-02-23 Bennett David B Methotrexate compositions
US7741317B2 (en) * 2005-10-21 2010-06-22 Bristol-Myers Squibb Company LXR modulators
CN102014919B (zh) 2008-03-03 2015-02-25 托斯克公司 减少毒性的甲氨蝶呤佐剂及其使用方法
EP2527322A1 (de) 2011-05-24 2012-11-28 Noscira, S.A. Carbamylalkylphenyldisulfidderivate und deren therapeutische Verwendungen

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2784670B2 (ja) * 1989-08-09 1998-08-06 株式会社シーエスケイ パチンコ景品交換システム
CA2088665C (en) * 1990-08-14 2001-05-01 Nobuhiro Ohi Methotrexate derivative
JPH04368385A (ja) * 1991-06-12 1992-12-21 Chugai Pharmaceut Co Ltd 新規メトトレキセート誘導体
ATE204576T1 (de) * 1992-01-27 2001-09-15 Chugai Pharmaceutical Co Ltd Methotrexat-derivate
JP3281099B2 (ja) * 1992-02-13 2002-05-13 中外製薬株式会社 抗リウマチ剤

Also Published As

Publication number Publication date
EP0676399A1 (de) 1995-10-11
CN1093365A (zh) 1994-10-12
DK0676399T3 (da) 2000-03-20
KR960700245A (ko) 1996-01-19
AU5715894A (en) 1994-07-19
WO1994014810A1 (en) 1994-07-07
ATE184605T1 (de) 1999-10-15
EP0676399B1 (de) 1999-09-15
ES2140524T3 (es) 2000-03-01
SG52733A1 (en) 1998-09-28
CN1037771C (zh) 1998-03-18
DE69326479T2 (de) 2000-03-02
KR100259742B1 (ko) 2000-07-01
EP0676399A4 (de) 1996-04-17
US5728692A (en) 1998-03-17
CA2152485A1 (en) 1994-07-07
GR3031864T3 (en) 2000-02-29

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee