ATE102937T1 - N-substituierte amid-derivate. - Google Patents

N-substituierte amid-derivate.

Info

Publication number
ATE102937T1
ATE102937T1 AT89306761T AT89306761T ATE102937T1 AT E102937 T1 ATE102937 T1 AT E102937T1 AT 89306761 T AT89306761 T AT 89306761T AT 89306761 T AT89306761 T AT 89306761T AT E102937 T1 ATE102937 T1 AT E102937T1
Authority
AT
Austria
Prior art keywords
amide derivatives
substituted amide
carbon atoms
alkyl group
chem
Prior art date
Application number
AT89306761T
Other languages
English (en)
Inventor
Geng-Tao Liu
Liang Huang
Er-Chang Rao
Jin Zhou
Yan Li
Katsuo Hatayama
Kensei Yoshikawa
Tatsuhiko Sano
Shohei Higuchi
Iwao Arai
Original Assignee
Taisho Pharmaceutical Co Ltd
Inst Of Materia Medica Of Chin
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Taisho Pharmaceutical Co Ltd, Inst Of Materia Medica Of Chin filed Critical Taisho Pharmaceutical Co Ltd
Application granted granted Critical
Publication of ATE102937T1 publication Critical patent/ATE102937T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/50—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
    • C07D317/58—Radicals substituted by nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
AT89306761T 1988-07-08 1989-07-04 N-substituierte amid-derivate. ATE102937T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP17072788 1988-07-08
EP89306761A EP0350251B1 (de) 1988-07-08 1989-07-04 N-substituierte Amid-Derivate

Publications (1)

Publication Number Publication Date
ATE102937T1 true ATE102937T1 (de) 1994-04-15

Family

ID=15910274

Family Applications (1)

Application Number Title Priority Date Filing Date
AT89306761T ATE102937T1 (de) 1988-07-08 1989-07-04 N-substituierte amid-derivate.

Country Status (7)

Country Link
US (1) US4937360A (de)
EP (1) EP0350251B1 (de)
JP (1) JPH02124884A (de)
KR (1) KR970002232B1 (de)
AT (1) ATE102937T1 (de)
CA (1) CA1328875C (de)
DE (1) DE68913835T2 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH05310678A (ja) * 1990-01-22 1993-11-22 Mitsubishi Kasei Corp １−フェニルアルキル−３−フェニル尿素誘導体
DE69331761T2 (de) * 1992-07-24 2002-09-12 The Regents Of The University Of California, Oakland Arzneimittel, die den durch ampa rezeptoren vermittelten synaptischen respons erhöhen
US5426225A (en) * 1993-12-30 1995-06-20 American Cyanamid Company Perfluoroalkanoyl aminonitriles
MY119161A (en) * 1994-04-18 2005-04-30 Novartis Ag Delta-amino-gamma-hydroxy-omega-aryl-alkanoic acid amides with enzyme especially renin inhibiting activities
US5852008A (en) * 1995-01-24 1998-12-22 The Regents Of The University Of California Heteroatom substituted benzoyl derivatives that enhance synaptic response mediated by receptors
KR100345203B1 (ko) * 2000-03-21 2002-07-24 현대자동차주식회사 리벳팅 장치
KR100345204B1 (ko) * 2000-03-21 2002-07-24 현대자동차주식회사 리벳 삽입 장치
KR20180057162A (ko) * 2016-11-22 2018-05-30 맥스엔지니어링(주) 면적차에 의해 연속 작동되는 피스톤과 절환 밸브가 내장된 선형 유체 펌프
CA3230380A1 (en) 2021-09-01 2023-03-09 Nicholas MORRA Synthesis of mdma or its optically active (r)- or (s)-mdma isomers
EP4408832A1 (de) 2021-10-01 2024-08-07 Empathibio, Inc. Neue prodrugs von mdma, mda und derivaten davon
US11912680B2 (en) 2021-12-28 2024-02-27 Empathbio, Inc. Nitric oxide releasing prodrugs of MDA and MDMA

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE332474C (de) * 1912-12-24 1921-02-01 Chem Fab Verfahren zur Darstellung von N-Alkyl-Acyl-Homopiperonylaminen
DE1543372A1 (de) * 1966-10-18 1971-04-01 Boehringer Sohn Ingelheim Verfahren zur Herstellung von o-substituierten 3,4-Dioxyphenylalkanolaminen
US4147799A (en) * 1971-06-24 1979-04-03 Kyowa Hakko Kogyo Co., Ltd. Process for reducing blood pressure and blocking β-adrenergic receptor
US4684651A (en) * 1981-03-17 1987-08-04 Mitsubishi Chemical Industries Limited Alkylenedioxybenzene and acid addition salts thereof useful as hypotensives
ES8203876A1 (es) * 1981-05-13 1982-04-01 Ferrer Int Procedimiento de obtencion de nuevos a-amino derivados ci- clicos del 1-(3',4'-metilendioxifenil)etanol
CH664565A5 (de) * 1985-05-09 1988-03-15 Ciba Geigy Ag Mittel zum schuetzen von kulturpflanzen vor der phytotoxischen wirkung von herbizid wirksamen chloracetaniliden.

Also Published As

Publication number Publication date
DE68913835D1 (de) 1994-04-21
DE68913835T2 (de) 1994-06-30
JPH02124884A (ja) 1990-05-14
KR970002232B1 (ko) 1997-02-26
KR900001673A (ko) 1990-02-27
EP0350251A2 (de) 1990-01-10
US4937360A (en) 1990-06-26
EP0350251A3 (en) 1990-03-14
CA1328875C (en) 1994-04-26
JPH0567634B2 (de) 1993-09-27
EP0350251B1 (de) 1994-03-16

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee