JPH0554935B2 - - Google Patents
Info
- Publication number
- JPH0554935B2 JPH0554935B2 JP59243009A JP24300984A JPH0554935B2 JP H0554935 B2 JPH0554935 B2 JP H0554935B2 JP 59243009 A JP59243009 A JP 59243009A JP 24300984 A JP24300984 A JP 24300984A JP H0554935 B2 JPH0554935 B2 JP H0554935B2
- Authority
- JP
- Japan
- Prior art keywords
- acid
- coupler
- silver halide
- silver
- compounds
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- -1 silver halide Chemical class 0.000 claims description 55
- 229910052709 silver Inorganic materials 0.000 claims description 33
- 239000004332 silver Substances 0.000 claims description 33
- 125000000217 alkyl group Chemical group 0.000 claims description 19
- 239000000839 emulsion Substances 0.000 claims description 14
- 239000000463 material Substances 0.000 claims description 14
- 239000003795 chemical substances by application Substances 0.000 claims description 9
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims description 6
- 239000000975 dye Substances 0.000 description 21
- 239000000243 solution Substances 0.000 description 19
- WSFSSNUMVMOOMR-UHFFFAOYSA-N Formaldehyde Chemical compound O=C WSFSSNUMVMOOMR-UHFFFAOYSA-N 0.000 description 16
- 238000011161 development Methods 0.000 description 14
- 150000001875 compounds Chemical class 0.000 description 13
- 239000010410 layer Substances 0.000 description 13
- 238000000034 method Methods 0.000 description 10
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 description 9
- QPCDCPDFJACHGM-UHFFFAOYSA-N N,N-bis{2-[bis(carboxymethyl)amino]ethyl}glycine Chemical compound OC(=O)CN(CC(O)=O)CCN(CC(=O)O)CCN(CC(O)=O)CC(O)=O QPCDCPDFJACHGM-UHFFFAOYSA-N 0.000 description 9
- 238000011282 treatment Methods 0.000 description 9
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 9
- 108010010803 Gelatin Proteins 0.000 description 8
- 239000002253 acid Substances 0.000 description 8
- 230000015572 biosynthetic process Effects 0.000 description 8
- 239000008273 gelatin Substances 0.000 description 8
- 229920000159 gelatin Polymers 0.000 description 8
- 235000019322 gelatine Nutrition 0.000 description 8
- 235000011852 gelatine desserts Nutrition 0.000 description 8
- 239000000203 mixture Substances 0.000 description 8
- 238000003786 synthesis reaction Methods 0.000 description 8
- KCXVZYZYPLLWCC-UHFFFAOYSA-N EDTA Chemical compound OC(=O)CN(CC(O)=O)CCN(CC(O)=O)CC(O)=O KCXVZYZYPLLWCC-UHFFFAOYSA-N 0.000 description 7
- CDBYLPFSWZWCQE-UHFFFAOYSA-L Sodium Carbonate Chemical compound [Na+].[Na+].[O-]C([O-])=O CDBYLPFSWZWCQE-UHFFFAOYSA-L 0.000 description 7
- 239000007788 liquid Substances 0.000 description 7
- 238000012545 processing Methods 0.000 description 7
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical group [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 6
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 description 6
- BQCADISMDOOEFD-UHFFFAOYSA-N Silver Chemical compound [Ag] BQCADISMDOOEFD-UHFFFAOYSA-N 0.000 description 6
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 6
- 229910052799 carbon Inorganic materials 0.000 description 6
- 229910052757 nitrogen Inorganic materials 0.000 description 6
- BWHMMNNQKKPAPP-UHFFFAOYSA-L potassium carbonate Chemical compound [K+].[K+].[O-]C([O-])=O BWHMMNNQKKPAPP-UHFFFAOYSA-L 0.000 description 6
- 150000003839 salts Chemical class 0.000 description 6
- UDFSJHJKINSRFV-UHFFFAOYSA-N N1N=CN2N=CC=C21 Chemical compound N1N=CN2N=CC=C21 UDFSJHJKINSRFV-UHFFFAOYSA-N 0.000 description 5
- 239000000654 additive Substances 0.000 description 5
- 238000004061 bleaching Methods 0.000 description 5
- 230000008878 coupling Effects 0.000 description 5
- 238000010168 coupling process Methods 0.000 description 5
- 238000005859 coupling reaction Methods 0.000 description 5
- 239000013078 crystal Substances 0.000 description 5
- 150000007524 organic acids Chemical class 0.000 description 5
- 125000001424 substituent group Chemical group 0.000 description 5
- CDAWCLOXVUBKRW-UHFFFAOYSA-N 2-aminophenol Chemical compound NC1=CC=CC=C1O CDAWCLOXVUBKRW-UHFFFAOYSA-N 0.000 description 4
- HEDRZPFGACZZDS-UHFFFAOYSA-N Chloroform Chemical compound ClC(Cl)Cl HEDRZPFGACZZDS-UHFFFAOYSA-N 0.000 description 4
- SJOOOZPMQAWAOP-UHFFFAOYSA-N [Ag].BrCl Chemical compound [Ag].BrCl SJOOOZPMQAWAOP-UHFFFAOYSA-N 0.000 description 4
- 239000006096 absorbing agent Substances 0.000 description 4
- 229960000583 acetic acid Drugs 0.000 description 4
- 150000007513 acids Chemical class 0.000 description 4
- 229910052783 alkali metal Inorganic materials 0.000 description 4
- 239000007844 bleaching agent Substances 0.000 description 4
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical class OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 description 4
- 238000004040 coloring Methods 0.000 description 4
- DOIRQSBPFJWKBE-UHFFFAOYSA-N dibutyl phthalate Chemical compound CCCCOC(=O)C1=CC=CC=C1C(=O)OCCCC DOIRQSBPFJWKBE-UHFFFAOYSA-N 0.000 description 4
- 238000011160 research Methods 0.000 description 4
- 230000001235 sensitizing effect Effects 0.000 description 4
- 239000002904 solvent Substances 0.000 description 4
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 description 3
- WEVYAHXRMPXWCK-UHFFFAOYSA-N Acetonitrile Chemical compound CC#N WEVYAHXRMPXWCK-UHFFFAOYSA-N 0.000 description 3
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 3
- UHOVQNZJYSORNB-UHFFFAOYSA-N Benzene Chemical compound C1=CC=CC=C1 UHOVQNZJYSORNB-UHFFFAOYSA-N 0.000 description 3
- MQIUGAXCHLFZKX-UHFFFAOYSA-N Di-n-octyl phthalate Natural products CCCCCCCCOC(=O)C1=CC=CC=C1C(=O)OCCCCCCCC MQIUGAXCHLFZKX-UHFFFAOYSA-N 0.000 description 3
- ZGTMUACCHSMWAC-UHFFFAOYSA-L EDTA disodium salt (anhydrous) Chemical compound [Na+].[Na+].OC(=O)CN(CC([O-])=O)CCN(CC(O)=O)CC([O-])=O ZGTMUACCHSMWAC-UHFFFAOYSA-L 0.000 description 3
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 3
- XEKOWRVHYACXOJ-UHFFFAOYSA-N Ethyl acetate Chemical compound CCOC(C)=O XEKOWRVHYACXOJ-UHFFFAOYSA-N 0.000 description 3
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 description 3
- MUBZPKHOEPUJKR-UHFFFAOYSA-N Oxalic acid Chemical compound OC(=O)C(O)=O MUBZPKHOEPUJKR-UHFFFAOYSA-N 0.000 description 3
- KWYUFKZDYYNOTN-UHFFFAOYSA-M Potassium hydroxide Chemical compound [OH-].[K+] KWYUFKZDYYNOTN-UHFFFAOYSA-M 0.000 description 3
- 238000010521 absorption reaction Methods 0.000 description 3
- 239000003513 alkali Substances 0.000 description 3
- 125000003545 alkoxy group Chemical group 0.000 description 3
- 125000004414 alkyl thio group Chemical group 0.000 description 3
- 125000003118 aryl group Chemical group 0.000 description 3
- 125000004391 aryl sulfonyl group Chemical group 0.000 description 3
- 125000005110 aryl thio group Chemical group 0.000 description 3
- 238000009835 boiling Methods 0.000 description 3
- 238000006243 chemical reaction Methods 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- 239000012362 glacial acetic acid Substances 0.000 description 3
- 229910052739 hydrogen Inorganic materials 0.000 description 3
- 239000001257 hydrogen Substances 0.000 description 3
- 229910000027 potassium carbonate Inorganic materials 0.000 description 3
- 235000011181 potassium carbonates Nutrition 0.000 description 3
- JEXVQSWXXUJEMA-UHFFFAOYSA-N pyrazol-3-one Chemical compound O=C1C=CN=N1 JEXVQSWXXUJEMA-UHFFFAOYSA-N 0.000 description 3
- 229910000029 sodium carbonate Inorganic materials 0.000 description 3
- 235000017550 sodium carbonate Nutrition 0.000 description 3
- ANRHNWWPFJCPAZ-UHFFFAOYSA-M thionine Chemical compound [Cl-].C1=CC(N)=CC2=[S+]C3=CC(N)=CC=C3N=C21 ANRHNWWPFJCPAZ-UHFFFAOYSA-M 0.000 description 3
- ZKGIQGUWLGYKMA-UHFFFAOYSA-N 1,2-bis(ethenylsulfonyl)ethane Chemical compound C=CS(=O)(=O)CCS(=O)(=O)C=C ZKGIQGUWLGYKMA-UHFFFAOYSA-N 0.000 description 2
- CLDZVCMRASJQFO-UHFFFAOYSA-N 2,5-bis(2,4,4-trimethylpentan-2-yl)benzene-1,4-diol Chemical compound CC(C)(C)CC(C)(C)C1=CC(O)=C(C(C)(C)CC(C)(C)C)C=C1O CLDZVCMRASJQFO-UHFFFAOYSA-N 0.000 description 2
- XNCSCQSQSGDGES-UHFFFAOYSA-N 2-[2-[bis(carboxymethyl)amino]propyl-(carboxymethyl)amino]acetic acid Chemical compound OC(=O)CN(CC(O)=O)C(C)CN(CC(O)=O)CC(O)=O XNCSCQSQSGDGES-UHFFFAOYSA-N 0.000 description 2
- ZZXILYOBAFPJNS-UHFFFAOYSA-N 2-octylbenzene-1,4-diol Chemical compound CCCCCCCCC1=CC(O)=CC=C1O ZZXILYOBAFPJNS-UHFFFAOYSA-N 0.000 description 2
- KWYJDIUEHHCHCZ-UHFFFAOYSA-N 3-[2-[bis(2-carboxyethyl)amino]ethyl-(2-carboxyethyl)amino]propanoic acid Chemical compound OC(=O)CCN(CCC(O)=O)CCN(CCC(O)=O)CCC(O)=O KWYJDIUEHHCHCZ-UHFFFAOYSA-N 0.000 description 2
- PLIKAWJENQZMHA-UHFFFAOYSA-N 4-aminophenol Chemical compound NC1=CC=C(O)C=C1 PLIKAWJENQZMHA-UHFFFAOYSA-N 0.000 description 2
- QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 description 2
- VHUUQVKOLVNVRT-UHFFFAOYSA-N Ammonium hydroxide Chemical compound [NH4+].[OH-] VHUUQVKOLVNVRT-UHFFFAOYSA-N 0.000 description 2
- PQUCIEFHOVEZAU-UHFFFAOYSA-N Diammonium sulfite Chemical compound [NH4+].[NH4+].[O-]S([O-])=O PQUCIEFHOVEZAU-UHFFFAOYSA-N 0.000 description 2
- MHAJPDPJQMAIIY-UHFFFAOYSA-N Hydrogen peroxide Chemical compound OO MHAJPDPJQMAIIY-UHFFFAOYSA-N 0.000 description 2
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 description 2
- AFVFQIVMOAPDHO-UHFFFAOYSA-N Methanesulfonic acid Chemical compound CS(O)(=O)=O AFVFQIVMOAPDHO-UHFFFAOYSA-N 0.000 description 2
- JRNVZBWKYDBUCA-UHFFFAOYSA-N N-chlorosuccinimide Chemical compound ClN1C(=O)CCC1=O JRNVZBWKYDBUCA-UHFFFAOYSA-N 0.000 description 2
- URLKBWYHVLBVBO-UHFFFAOYSA-N Para-Xylene Chemical compound CC1=CC=C(C)C=C1 URLKBWYHVLBVBO-UHFFFAOYSA-N 0.000 description 2
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 2
- YSMRWXYRXBRSND-UHFFFAOYSA-N TOTP Chemical compound CC1=CC=CC=C1OP(=O)(OC=1C(=CC=CC=1)C)OC1=CC=CC=C1C YSMRWXYRXBRSND-UHFFFAOYSA-N 0.000 description 2
- AUJUKHGWOKKPAN-UHFFFAOYSA-J [Na+].[Na+].[Na+].[Na+].CC(CN(CC([O-])=O)CC([O-])=O)N(CC([O-])=O)CC([O-])=O Chemical compound [Na+].[Na+].[Na+].[Na+].CC(CN(CC([O-])=O)CC([O-])=O)N(CC([O-])=O)CC([O-])=O AUJUKHGWOKKPAN-UHFFFAOYSA-J 0.000 description 2
- LRSAWRZHGQQHBJ-UHFFFAOYSA-N acetic acid;benzene-1,2-diamine Chemical compound CC(O)=O.CC(O)=O.CC(O)=O.CC(O)=O.NC1=CC=CC=C1N LRSAWRZHGQQHBJ-UHFFFAOYSA-N 0.000 description 2
- 125000004644 alkyl sulfinyl group Chemical group 0.000 description 2
- 125000004390 alkyl sulfonyl group Chemical group 0.000 description 2
- SWLVFNYSXGMGBS-UHFFFAOYSA-N ammonium bromide Chemical compound [NH4+].[Br-] SWLVFNYSXGMGBS-UHFFFAOYSA-N 0.000 description 2
- 235000011114 ammonium hydroxide Nutrition 0.000 description 2
- XYXNTHIYBIDHGM-UHFFFAOYSA-N ammonium thiosulfate Chemical compound [NH4+].[NH4+].[O-]S([O-])(=O)=S XYXNTHIYBIDHGM-UHFFFAOYSA-N 0.000 description 2
- 239000003963 antioxidant agent Substances 0.000 description 2
- 230000003078 antioxidant effect Effects 0.000 description 2
- 239000007864 aqueous solution Substances 0.000 description 2
- 125000005135 aryl sulfinyl group Chemical group 0.000 description 2
- BJQHLKABXJIVAM-UHFFFAOYSA-N bis(2-ethylhexyl) phthalate Chemical compound CCCCC(CC)COC(=O)C1=CC=CC=C1C(=O)OCC(CC)CCCC BJQHLKABXJIVAM-UHFFFAOYSA-N 0.000 description 2
- 239000011248 coating agent Substances 0.000 description 2
- 238000000576 coating method Methods 0.000 description 2
- 238000001816 cooling Methods 0.000 description 2
- 239000006185 dispersion Substances 0.000 description 2
- DEFVIWRASFVYLL-UHFFFAOYSA-N ethylene glycol bis(2-aminoethyl)tetraacetic acid Chemical compound OC(=O)CN(CC(O)=O)CCOCCOCCN(CC(O)=O)CC(O)=O DEFVIWRASFVYLL-UHFFFAOYSA-N 0.000 description 2
- 229940093915 gynecological organic acid Drugs 0.000 description 2
- 229910052736 halogen Inorganic materials 0.000 description 2
- 125000000623 heterocyclic group Chemical group 0.000 description 2
- NBZBKCUXIYYUSX-UHFFFAOYSA-N iminodiacetic acid Chemical compound OC(=O)CNCC(O)=O NBZBKCUXIYYUSX-UHFFFAOYSA-N 0.000 description 2
- DZVCFNFOPIZQKX-LTHRDKTGSA-M merocyanine Chemical compound [Na+].O=C1N(CCCC)C(=O)N(CCCC)C(=O)C1=C\C=C\C=C/1N(CCCS([O-])(=O)=O)C2=CC=CC=C2O\1 DZVCFNFOPIZQKX-LTHRDKTGSA-M 0.000 description 2
- 229910052751 metal Inorganic materials 0.000 description 2
- 239000002184 metal Substances 0.000 description 2
- MGFYIUFZLHCRTH-UHFFFAOYSA-N nitrilotriacetic acid Chemical compound OC(=O)CN(CC(O)=O)CC(O)=O MGFYIUFZLHCRTH-UHFFFAOYSA-N 0.000 description 2
- 125000004433 nitrogen atom Chemical group N* 0.000 description 2
- 235000005985 organic acids Nutrition 0.000 description 2
- 239000003960 organic solvent Substances 0.000 description 2
- 239000007800 oxidant agent Substances 0.000 description 2
- 229910052760 oxygen Inorganic materials 0.000 description 2
- 239000001301 oxygen Substances 0.000 description 2
- LQPLDXQVILYOOL-UHFFFAOYSA-I pentasodium;2-[bis[2-[bis(carboxylatomethyl)amino]ethyl]amino]acetate Chemical compound [Na+].[Na+].[Na+].[Na+].[Na+].[O-]C(=O)CN(CC([O-])=O)CCN(CC(=O)[O-])CCN(CC([O-])=O)CC([O-])=O LQPLDXQVILYOOL-UHFFFAOYSA-I 0.000 description 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 description 2
- IOLCXVTUBQKXJR-UHFFFAOYSA-M potassium bromide Chemical compound [K+].[Br-] IOLCXVTUBQKXJR-UHFFFAOYSA-M 0.000 description 2
- 230000035945 sensitivity Effects 0.000 description 2
- ZUNKMNLKJXRCDM-UHFFFAOYSA-N silver bromoiodide Chemical compound [Ag].IBr ZUNKMNLKJXRCDM-UHFFFAOYSA-N 0.000 description 2
- JHJLBTNAGRQEKS-UHFFFAOYSA-M sodium bromide Chemical compound [Na+].[Br-] JHJLBTNAGRQEKS-UHFFFAOYSA-M 0.000 description 2
- HRZFUMHJMZEROT-UHFFFAOYSA-L sodium disulfite Chemical compound [Na+].[Na+].[O-]S(=O)S([O-])(=O)=O HRZFUMHJMZEROT-UHFFFAOYSA-L 0.000 description 2
- 229940001584 sodium metabisulfite Drugs 0.000 description 2
- 235000010262 sodium metabisulphite Nutrition 0.000 description 2
- DZCAZXAJPZCSCU-UHFFFAOYSA-K sodium nitrilotriacetate Chemical compound [Na+].[Na+].[Na+].[O-]C(=O)CN(CC([O-])=O)CC([O-])=O DZCAZXAJPZCSCU-UHFFFAOYSA-K 0.000 description 2
- 230000000087 stabilizing effect Effects 0.000 description 2
- KZNICNPSHKQLFF-UHFFFAOYSA-N succinimide Chemical compound O=C1CCC(=O)N1 KZNICNPSHKQLFF-UHFFFAOYSA-N 0.000 description 2
- 229910052717 sulfur Inorganic materials 0.000 description 2
- 125000004434 sulfur atom Chemical group 0.000 description 2
- 238000001308 synthesis method Methods 0.000 description 2
- UEUXEKPTXMALOB-UHFFFAOYSA-J tetrasodium;2-[2-[bis(carboxylatomethyl)amino]ethyl-(carboxylatomethyl)amino]acetate Chemical compound [Na+].[Na+].[Na+].[Na+].[O-]C(=O)CN(CC([O-])=O)CCN(CC([O-])=O)CC([O-])=O UEUXEKPTXMALOB-UHFFFAOYSA-J 0.000 description 2
- 239000006097 ultraviolet radiation absorber Substances 0.000 description 2
- 150000005208 1,4-dihydroxybenzenes Chemical class 0.000 description 1
- AOSFMYBATFLTAQ-UHFFFAOYSA-N 1-amino-3-(benzimidazol-1-yl)propan-2-ol Chemical compound C1=CC=C2N(CC(O)CN)C=NC2=C1 AOSFMYBATFLTAQ-UHFFFAOYSA-N 0.000 description 1
- HRBLHUVHOWWBEN-UHFFFAOYSA-N 1-n,4-n-diethylbenzene-1,4-diamine;hydrochloride Chemical compound Cl.CCNC1=CC=C(NCC)C=C1 HRBLHUVHOWWBEN-UHFFFAOYSA-N 0.000 description 1
- NEPWWHQLHRGVQL-UHFFFAOYSA-N 1-n,4-n-dimethylbenzene-1,4-diamine;hydron;chloride Chemical compound Cl.CNC1=CC=C(NC)C=C1 NEPWWHQLHRGVQL-UHFFFAOYSA-N 0.000 description 1
- YGDWUQFZMXWDKE-UHFFFAOYSA-N 1-oxido-1,3-thiazole Chemical class [O-]S1=CN=C=C1 YGDWUQFZMXWDKE-UHFFFAOYSA-N 0.000 description 1
- KPVMVJXYXFUVLR-UHFFFAOYSA-N 12-ethyltetradecan-1-amine Chemical compound CCC(CC)CCCCCCCCCCCN KPVMVJXYXFUVLR-UHFFFAOYSA-N 0.000 description 1
- CSDAVVDYVFLHLF-UHFFFAOYSA-N 2,3-bis(2-methylbutan-2-yl)-1,4-dioctoxybenzene Chemical compound CCCCCCCCOC1=CC=C(OCCCCCCCC)C(C(C)(C)CC)=C1C(C)(C)CC CSDAVVDYVFLHLF-UHFFFAOYSA-N 0.000 description 1
- ALQQNXBDAKRPOQ-UHFFFAOYSA-N 2-(2-ethyl-2-phenylhydrazinyl)ethanol Chemical compound OCCNN(CC)C1=CC=CC=C1 ALQQNXBDAKRPOQ-UHFFFAOYSA-N 0.000 description 1
- JKRNNIGZNCVVHA-UHFFFAOYSA-N 2-[2-[bis(carboxylatomethyl)amino]ethyl-(carboxylatomethyl)amino]acetate;trimethylazanium Chemical compound C[NH+](C)C.C[NH+](C)C.C[NH+](C)C.C[NH+](C)C.[O-]C(=O)CN(CC([O-])=O)CCN(CC([O-])=O)CC([O-])=O JKRNNIGZNCVVHA-UHFFFAOYSA-N 0.000 description 1
- JKFYKCYQEWQPTM-UHFFFAOYSA-N 2-azaniumyl-2-(4-fluorophenyl)acetate Chemical compound OC(=O)C(N)C1=CC=C(F)C=C1 JKFYKCYQEWQPTM-UHFFFAOYSA-N 0.000 description 1
- DPQNJTSTJKBEQO-UHFFFAOYSA-N 3,5-dibromo-2,2,6,6-tetramethylheptan-4-one Chemical compound CC(C)(C)C(Br)C(=O)C(Br)C(C)(C)C DPQNJTSTJKBEQO-UHFFFAOYSA-N 0.000 description 1
- XRZDIHADHZSFBB-UHFFFAOYSA-N 3-oxo-n,3-diphenylpropanamide Chemical compound C=1C=CC=CC=1NC(=O)CC(=O)C1=CC=CC=C1 XRZDIHADHZSFBB-UHFFFAOYSA-N 0.000 description 1
- FWBHETKCLVMNFS-UHFFFAOYSA-N 4',6-Diamino-2-phenylindol Chemical compound C1=CC(C(=N)N)=CC=C1C1=CC2=CC=C(C(N)=N)C=C2N1 FWBHETKCLVMNFS-UHFFFAOYSA-N 0.000 description 1
- VPWNQTHUCYMVMZ-UHFFFAOYSA-N 4,4'-sulfonyldiphenol Chemical class C1=CC(O)=CC=C1S(=O)(=O)C1=CC=C(O)C=C1 VPWNQTHUCYMVMZ-UHFFFAOYSA-N 0.000 description 1
- YLNKRLLYLJYWEN-UHFFFAOYSA-N 4-(2,2-dibutoxyethoxy)-4-oxobutanoic acid Chemical compound CCCCOC(OCCCC)COC(=O)CCC(O)=O YLNKRLLYLJYWEN-UHFFFAOYSA-N 0.000 description 1
- MTOCKMVNXPZCJW-UHFFFAOYSA-N 4-n-dodecyl-4-n-ethyl-2-methylbenzene-1,4-diamine Chemical compound CCCCCCCCCCCCN(CC)C1=CC=C(N)C(C)=C1 MTOCKMVNXPZCJW-UHFFFAOYSA-N 0.000 description 1
- IJJSFSXLZYFTKV-UHFFFAOYSA-N 4-n-methylbenzene-1,4-diamine;hydrochloride Chemical compound Cl.CNC1=CC=C(N)C=C1 IJJSFSXLZYFTKV-UHFFFAOYSA-N 0.000 description 1
- 125000002373 5 membered heterocyclic group Chemical group 0.000 description 1
- 229940100484 5-chloro-2-methyl-4-isothiazolin-3-one Drugs 0.000 description 1
- 125000004070 6 membered heterocyclic group Chemical group 0.000 description 1
- QZCLKYGREBVARF-UHFFFAOYSA-N Acetyl tributyl citrate Chemical compound CCCCOC(=O)CC(C(=O)OCCCC)(OC(C)=O)CC(=O)OCCCC QZCLKYGREBVARF-UHFFFAOYSA-N 0.000 description 1
- 229930185605 Bisphenol Natural products 0.000 description 1
- KAKZBPTYRLMSJV-UHFFFAOYSA-N Butadiene Chemical class C=CC=C KAKZBPTYRLMSJV-UHFFFAOYSA-N 0.000 description 1
- RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 description 1
- MYMOFIZGZYHOMD-UHFFFAOYSA-N Dioxygen Chemical compound O=O MYMOFIZGZYHOMD-UHFFFAOYSA-N 0.000 description 1
- 239000003109 Disodium ethylene diamine tetraacetate Substances 0.000 description 1
- 238000005481 NMR spectroscopy Methods 0.000 description 1
- 229910019142 PO4 Inorganic materials 0.000 description 1
- 206010034972 Photosensitivity reaction Diseases 0.000 description 1
- 229920003171 Poly (ethylene oxide) Polymers 0.000 description 1
- XBDQKXXYIPTUBI-UHFFFAOYSA-N Propionic acid Substances CCC(O)=O XBDQKXXYIPTUBI-UHFFFAOYSA-N 0.000 description 1
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 1
- 229910021607 Silver chloride Inorganic materials 0.000 description 1
- 229910021612 Silver iodide Inorganic materials 0.000 description 1
- VMHLLURERBWHNL-UHFFFAOYSA-M Sodium acetate Chemical compound [Na+].CC([O-])=O VMHLLURERBWHNL-UHFFFAOYSA-M 0.000 description 1
- UIIMBOGNXHQVGW-DEQYMQKBSA-M Sodium bicarbonate-14C Chemical compound [Na+].O[14C]([O-])=O UIIMBOGNXHQVGW-DEQYMQKBSA-M 0.000 description 1
- DWAQJAXMDSEUJJ-UHFFFAOYSA-M Sodium bisulfite Chemical compound [Na+].OS([O-])=O DWAQJAXMDSEUJJ-UHFFFAOYSA-M 0.000 description 1
- LSNNMFCWUKXFEE-UHFFFAOYSA-N Sulfurous acid Chemical compound OS(O)=O LSNNMFCWUKXFEE-UHFFFAOYSA-N 0.000 description 1
- FEWJPZIEWOKRBE-UHFFFAOYSA-N Tartaric acid Natural products [H+].[H+].[O-]C(=O)C(O)C(O)C([O-])=O FEWJPZIEWOKRBE-UHFFFAOYSA-N 0.000 description 1
- LJTFFORYSFGNCT-UHFFFAOYSA-N Thiocarbohydrazide Chemical compound NNC(=S)NN LJTFFORYSFGNCT-UHFFFAOYSA-N 0.000 description 1
- ZMZDMBWJUHKJPS-UHFFFAOYSA-M Thiocyanate anion Chemical compound [S-]C#N ZMZDMBWJUHKJPS-UHFFFAOYSA-M 0.000 description 1
- GWEVSGVZZGPLCZ-UHFFFAOYSA-N Titan oxide Chemical compound O=[Ti]=O GWEVSGVZZGPLCZ-UHFFFAOYSA-N 0.000 description 1
- XCFIVNQHHFZRNR-UHFFFAOYSA-N [Ag].Cl[IH]Br Chemical compound [Ag].Cl[IH]Br XCFIVNQHHFZRNR-UHFFFAOYSA-N 0.000 description 1
- 235000011054 acetic acid Nutrition 0.000 description 1
- 150000001242 acetic acid derivatives Chemical class 0.000 description 1
- 125000002252 acyl group Chemical group 0.000 description 1
- 125000004442 acylamino group Chemical group 0.000 description 1
- 125000004423 acyloxy group Chemical group 0.000 description 1
- 125000005073 adamantyl group Chemical group C12(CC3CC(CC(C1)C3)C2)* 0.000 description 1
- 230000000996 additive effect Effects 0.000 description 1
- 239000003570 air Substances 0.000 description 1
- 229910001508 alkali metal halide Inorganic materials 0.000 description 1
- 150000008045 alkali metal halides Chemical class 0.000 description 1
- 125000004453 alkoxycarbonyl group Chemical group 0.000 description 1
- 150000003973 alkyl amines Chemical class 0.000 description 1
- 239000000908 ammonium hydroxide Substances 0.000 description 1
- 150000003863 ammonium salts Chemical class 0.000 description 1
- 229940101006 anhydrous sodium sulfite Drugs 0.000 description 1
- 125000004104 aryloxy group Chemical group 0.000 description 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
- DKFFVMCMYIVCMK-UHFFFAOYSA-N azane 2-[2-[bis(carboxymethyl)amino]ethyl-(carboxymethyl)amino]acetic acid dihydrate Chemical compound O.[OH-].[NH4+].C(CN(CC(=O)O)CC(=O)O)N(CC(=O)O)CC(=O)O DKFFVMCMYIVCMK-UHFFFAOYSA-N 0.000 description 1
- XNSQZBOCSSMHSZ-UHFFFAOYSA-K azane;2-[2-[bis(carboxylatomethyl)amino]ethyl-(carboxymethyl)amino]acetate;iron(3+) Chemical compound [NH4+].[Fe+3].[O-]C(=O)CN(CC([O-])=O)CCN(CC([O-])=O)CC([O-])=O XNSQZBOCSSMHSZ-UHFFFAOYSA-K 0.000 description 1
- QVQLCTNNEUAWMS-UHFFFAOYSA-N barium oxide Chemical compound [Ba]=O QVQLCTNNEUAWMS-UHFFFAOYSA-N 0.000 description 1
- 229910001864 baryta Inorganic materials 0.000 description 1
- 239000002585 base Substances 0.000 description 1
- 150000001558 benzoic acid derivatives Chemical class 0.000 description 1
- 150000008366 benzophenones Chemical class 0.000 description 1
- 150000001565 benzotriazoles Chemical group 0.000 description 1
- 235000010290 biphenyl Nutrition 0.000 description 1
- 239000004305 biphenyl Substances 0.000 description 1
- 125000006267 biphenyl group Chemical group 0.000 description 1
- 229910021538 borax Inorganic materials 0.000 description 1
- KGBXLFKZBHKPEV-UHFFFAOYSA-N boric acid Chemical compound OB(O)O KGBXLFKZBHKPEV-UHFFFAOYSA-N 0.000 description 1
- 239000004327 boric acid Substances 0.000 description 1
- 229960002645 boric acid Drugs 0.000 description 1
- 235000010338 boric acid Nutrition 0.000 description 1
- 150000001642 boronic acid derivatives Chemical class 0.000 description 1
- SXDBWCPKPHAZSM-UHFFFAOYSA-M bromate Inorganic materials [O-]Br(=O)=O SXDBWCPKPHAZSM-UHFFFAOYSA-M 0.000 description 1
- SXDBWCPKPHAZSM-UHFFFAOYSA-N bromic acid Chemical compound OBr(=O)=O SXDBWCPKPHAZSM-UHFFFAOYSA-N 0.000 description 1
- 230000031709 bromination Effects 0.000 description 1
- 238000005893 bromination reaction Methods 0.000 description 1
- 239000000872 buffer Substances 0.000 description 1
- COPHVUDURPSYBO-UHFFFAOYSA-N butyl dioctyl phosphate Chemical compound CCCCCCCCOP(=O)(OCCCC)OCCCCCCCC COPHVUDURPSYBO-UHFFFAOYSA-N 0.000 description 1
- 150000004649 carbonic acid derivatives Chemical class 0.000 description 1
- 125000002915 carbonyl group Chemical group [*:2]C([*:1])=O 0.000 description 1
- 239000000969 carrier Substances 0.000 description 1
- 239000002738 chelating agent Substances 0.000 description 1
- DHNRXBZYEKSXIM-UHFFFAOYSA-N chloromethylisothiazolinone Chemical compound CN1SC(Cl)=CC1=O DHNRXBZYEKSXIM-UHFFFAOYSA-N 0.000 description 1
- 229940114081 cinnamate Drugs 0.000 description 1
- 229910017052 cobalt Inorganic materials 0.000 description 1
- 239000010941 cobalt Substances 0.000 description 1
- GUTLYIVDDKVIGB-UHFFFAOYSA-N cobalt atom Chemical compound [Co] GUTLYIVDDKVIGB-UHFFFAOYSA-N 0.000 description 1
- 239000000084 colloidal system Substances 0.000 description 1
- 239000003086 colorant Substances 0.000 description 1
- 238000004440 column chromatography Methods 0.000 description 1
- 230000000052 comparative effect Effects 0.000 description 1
- 238000007796 conventional method Methods 0.000 description 1
- 229910052802 copper Inorganic materials 0.000 description 1
- 239000010949 copper Substances 0.000 description 1
- 238000012937 correction Methods 0.000 description 1
- 239000003431 cross linking reagent Substances 0.000 description 1
- 125000004093 cyano group Chemical group *C#N 0.000 description 1
- 125000004663 dialkyl amino group Chemical group 0.000 description 1
- 235000014113 dietary fatty acids Nutrition 0.000 description 1
- 229910001873 dinitrogen Inorganic materials 0.000 description 1
- 235000019301 disodium ethylene diamine tetraacetate Nutrition 0.000 description 1
- PCAXGMRPPOMODZ-UHFFFAOYSA-N disulfurous acid, diammonium salt Chemical compound [NH4+].[NH4+].[O-]S(=O)S([O-])(=O)=O PCAXGMRPPOMODZ-UHFFFAOYSA-N 0.000 description 1
- SNRUBQQJIBEYMU-UHFFFAOYSA-N dodecane Chemical compound CCCCCCCCCCCC SNRUBQQJIBEYMU-UHFFFAOYSA-N 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 description 1
- 238000005562 fading Methods 0.000 description 1
- 239000000194 fatty acid Substances 0.000 description 1
- 229930195729 fatty acid Natural products 0.000 description 1
- LNTHITQWFMADLM-UHFFFAOYSA-N gallic acid Chemical class OC(=O)C1=CC(O)=C(O)C(O)=C1 LNTHITQWFMADLM-UHFFFAOYSA-N 0.000 description 1
- 239000007789 gas Substances 0.000 description 1
- 150000004820 halides Chemical class 0.000 description 1
- 125000004438 haloalkoxy group Chemical group 0.000 description 1
- 125000005843 halogen group Chemical group 0.000 description 1
- 150000002367 halogens Chemical group 0.000 description 1
- 125000005842 heteroatom Chemical group 0.000 description 1
- 150000003840 hydrochlorides Chemical class 0.000 description 1
- ZMZDMBWJUHKJPS-UHFFFAOYSA-N hydrogen thiocyanate Natural products SC#N ZMZDMBWJUHKJPS-UHFFFAOYSA-N 0.000 description 1
- LOCAIGRSOJUCTB-UHFFFAOYSA-N indazol-3-one Chemical class C1=CC=C2C(=O)N=NC2=C1 LOCAIGRSOJUCTB-UHFFFAOYSA-N 0.000 description 1
- 239000003112 inhibitor Substances 0.000 description 1
- 239000011229 interlayer Substances 0.000 description 1
- 229910052742 iron Inorganic materials 0.000 description 1
- 239000002650 laminated plastic Substances 0.000 description 1
- 229910021645 metal ion Inorganic materials 0.000 description 1
- 229940098779 methanesulfonic acid Drugs 0.000 description 1
- 239000012046 mixed solvent Substances 0.000 description 1
- CLJDCQWROXMJAZ-UHFFFAOYSA-N n-[2-(4-amino-n-ethyl-3-methylanilino)ethyl]methanesulfonamide;sulfuric acid Chemical compound OS(O)(=O)=O.CS(=O)(=O)NCCN(CC)C1=CC=C(N)C(C)=C1 CLJDCQWROXMJAZ-UHFFFAOYSA-N 0.000 description 1
- 229940094933 n-dodecane Drugs 0.000 description 1
- 150000004780 naphthols Chemical class 0.000 description 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 description 1
- XNGIFLGASWRNHJ-UHFFFAOYSA-N o-dicarboxybenzene Natural products OC(=O)C1=CC=CC=C1C(O)=O XNGIFLGASWRNHJ-UHFFFAOYSA-N 0.000 description 1
- VECVSKFWRQYTAL-UHFFFAOYSA-N octyl benzoate Chemical compound CCCCCCCCOC(=O)C1=CC=CC=C1 VECVSKFWRQYTAL-UHFFFAOYSA-N 0.000 description 1
- 125000000962 organic group Chemical group 0.000 description 1
- 150000003891 oxalate salts Chemical class 0.000 description 1
- 235000006408 oxalic acid Nutrition 0.000 description 1
- 230000001590 oxidative effect Effects 0.000 description 1
- 125000004430 oxygen atom Chemical group O* 0.000 description 1
- 150000004989 p-phenylenediamines Chemical class 0.000 description 1
- 239000006179 pH buffering agent Substances 0.000 description 1
- 229960003330 pentetic acid Drugs 0.000 description 1
- JRKICGRDRMAZLK-UHFFFAOYSA-L peroxydisulfate Chemical compound [O-]S(=O)(=O)OOS([O-])(=O)=O JRKICGRDRMAZLK-UHFFFAOYSA-L 0.000 description 1
- 150000002989 phenols Chemical class 0.000 description 1
- WVDDGKGOMKODPV-ZQBYOMGUSA-N phenyl(114C)methanol Chemical compound O[14CH2]C1=CC=CC=C1 WVDDGKGOMKODPV-ZQBYOMGUSA-N 0.000 description 1
- ZUOUZKKEUPVFJK-UHFFFAOYSA-N phenylbenzene Natural products C1=CC=CC=C1C1=CC=CC=C1 ZUOUZKKEUPVFJK-UHFFFAOYSA-N 0.000 description 1
- 235000021317 phosphate Nutrition 0.000 description 1
- 150000003013 phosphoric acid derivatives Chemical class 0.000 description 1
- 150000003014 phosphoric acid esters Chemical class 0.000 description 1
- 230000036211 photosensitivity Effects 0.000 description 1
- 229920006255 plastic film Polymers 0.000 description 1
- 239000002985 plastic film Substances 0.000 description 1
- 229920000728 polyester Polymers 0.000 description 1
- 229920013716 polyethylene resin Polymers 0.000 description 1
- 229920000642 polymer Polymers 0.000 description 1
- 239000011736 potassium bicarbonate Substances 0.000 description 1
- 235000015497 potassium bicarbonate Nutrition 0.000 description 1
- 229910000028 potassium bicarbonate Inorganic materials 0.000 description 1
- DJEHXEMURTVAOE-UHFFFAOYSA-M potassium bisulfite Chemical compound [K+].OS([O-])=O DJEHXEMURTVAOE-UHFFFAOYSA-M 0.000 description 1
- 229940099427 potassium bisulfite Drugs 0.000 description 1
- 235000010259 potassium hydrogen sulphite Nutrition 0.000 description 1
- TYJJADVDDVDEDZ-UHFFFAOYSA-M potassium hydrogencarbonate Chemical compound [K+].OC([O-])=O TYJJADVDDVDEDZ-UHFFFAOYSA-M 0.000 description 1
- RWPGFSMJFRPDDP-UHFFFAOYSA-L potassium metabisulfite Chemical compound [K+].[K+].[O-]S(=O)S([O-])(=O)=O RWPGFSMJFRPDDP-UHFFFAOYSA-L 0.000 description 1
- 229940043349 potassium metabisulfite Drugs 0.000 description 1
- 235000010263 potassium metabisulphite Nutrition 0.000 description 1
- BHZRJJOHZFYXTO-UHFFFAOYSA-L potassium sulfite Chemical compound [K+].[K+].[O-]S([O-])=O BHZRJJOHZFYXTO-UHFFFAOYSA-L 0.000 description 1
- 235000019252 potassium sulphite Nutrition 0.000 description 1
- 150000003142 primary aromatic amines Chemical class 0.000 description 1
- 238000003672 processing method Methods 0.000 description 1
- 239000011241 protective layer Substances 0.000 description 1
- MCSKRVKAXABJLX-UHFFFAOYSA-N pyrazolo[3,4-d]triazole Chemical class N1=NN=C2N=NC=C21 MCSKRVKAXABJLX-UHFFFAOYSA-N 0.000 description 1
- 238000010992 reflux Methods 0.000 description 1
- 239000000741 silica gel Substances 0.000 description 1
- 229910002027 silica gel Inorganic materials 0.000 description 1
- ADZWSOLPGZMUMY-UHFFFAOYSA-M silver bromide Chemical compound [Ag]Br ADZWSOLPGZMUMY-UHFFFAOYSA-M 0.000 description 1
- 229940045105 silver iodide Drugs 0.000 description 1
- HKZLPVFGJNLROG-UHFFFAOYSA-M silver monochloride Chemical compound [Cl-].[Ag+] HKZLPVFGJNLROG-UHFFFAOYSA-M 0.000 description 1
- 239000001632 sodium acetate Substances 0.000 description 1
- 235000017281 sodium acetate Nutrition 0.000 description 1
- XUXNAKZDHHEHPC-UHFFFAOYSA-M sodium bromate Chemical compound [Na+].[O-]Br(=O)=O XUXNAKZDHHEHPC-UHFFFAOYSA-M 0.000 description 1
- 239000011780 sodium chloride Substances 0.000 description 1
- APSBXTVYXVQYAB-UHFFFAOYSA-M sodium docusate Chemical group [Na+].CCCCC(CC)COC(=O)CC(S([O-])(=O)=O)C(=O)OCC(CC)CCCC APSBXTVYXVQYAB-UHFFFAOYSA-M 0.000 description 1
- 235000010267 sodium hydrogen sulphite Nutrition 0.000 description 1
- GEHJYWRUCIMESM-UHFFFAOYSA-L sodium sulfite Chemical compound [Na+].[Na+].[O-]S([O-])=O GEHJYWRUCIMESM-UHFFFAOYSA-L 0.000 description 1
- 235000010339 sodium tetraborate Nutrition 0.000 description 1
- 239000004328 sodium tetraborate Substances 0.000 description 1
- GGCZERPQGJTIQP-UHFFFAOYSA-N sodium;9,10-dioxoanthracene-2-sulfonic acid Chemical compound [Na+].C1=CC=C2C(=O)C3=CC(S(=O)(=O)O)=CC=C3C(=O)C2=C1 GGCZERPQGJTIQP-UHFFFAOYSA-N 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 230000003595 spectral effect Effects 0.000 description 1
- 230000006641 stabilisation Effects 0.000 description 1
- 238000011105 stabilization Methods 0.000 description 1
- 125000005504 styryl group Chemical group 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 229960002317 succinimide Drugs 0.000 description 1
- LSNNMFCWUKXFEE-UHFFFAOYSA-L sulfite Chemical class [O-]S([O-])=O LSNNMFCWUKXFEE-UHFFFAOYSA-L 0.000 description 1
- 229940124530 sulfonamide Drugs 0.000 description 1
- 150000003456 sulfonamides Chemical class 0.000 description 1
- BDHFUVZGWQCTTF-UHFFFAOYSA-M sulfonate Chemical compound [O-]S(=O)=O BDHFUVZGWQCTTF-UHFFFAOYSA-M 0.000 description 1
- 125000000472 sulfonyl group Chemical group *S(*)(=O)=O 0.000 description 1
- 150000003467 sulfuric acid derivatives Chemical class 0.000 description 1
- 235000002906 tartaric acid Nutrition 0.000 description 1
- 239000011975 tartaric acid Substances 0.000 description 1
- 125000000999 tert-butyl group Chemical group [H]C([H])([H])C(*)(C([H])([H])[H])C([H])([H])[H] 0.000 description 1
- 239000002562 thickening agent Substances 0.000 description 1
- DHCDFWKWKRSZHF-UHFFFAOYSA-L thiosulfate(2-) Chemical compound [O-]S([S-])(=O)=O DHCDFWKWKRSZHF-UHFFFAOYSA-L 0.000 description 1
- OGIDPMRJRNCKJF-UHFFFAOYSA-N titanium oxide Inorganic materials [Ti]=O OGIDPMRJRNCKJF-UHFFFAOYSA-N 0.000 description 1
- 150000003852 triazoles Chemical class 0.000 description 1
- NJPOTNJJCSJJPJ-UHFFFAOYSA-N tributyl benzene-1,3,5-tricarboxylate Chemical compound CCCCOC(=O)C1=CC(C(=O)OCCCC)=CC(C(=O)OCCCC)=C1 NJPOTNJJCSJJPJ-UHFFFAOYSA-N 0.000 description 1
- 150000003639 trimesic acids Chemical class 0.000 description 1
- XZZNDPSIHUTMOC-UHFFFAOYSA-N triphenyl phosphate Chemical compound C=1C=CC=CC=1OP(OC=1C=CC=CC=1)(=O)OC1=CC=CC=C1 XZZNDPSIHUTMOC-UHFFFAOYSA-N 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
Classifications
-
- G—PHYSICS
- G03—PHOTOGRAPHY; CINEMATOGRAPHY; ANALOGOUS TECHNIQUES USING WAVES OTHER THAN OPTICAL WAVES; ELECTROGRAPHY; HOLOGRAPHY
- G03C—PHOTOSENSITIVE MATERIALS FOR PHOTOGRAPHIC PURPOSES; PHOTOGRAPHIC PROCESSES, e.g. CINE, X-RAY, COLOUR, STEREO-PHOTOGRAPHIC PROCESSES; AUXILIARY PROCESSES IN PHOTOGRAPHY
- G03C7/00—Multicolour photographic processes or agents therefor; Regeneration of such processing agents; Photosensitive materials for multicolour processes
- G03C7/30—Colour processes using colour-coupling substances; Materials therefor; Preparing or processing such materials
- G03C7/32—Colour coupling substances
- G03C7/36—Couplers containing compounds with active methylene groups
- G03C7/38—Couplers containing compounds with active methylene groups in rings
- G03C7/381—Heterocyclic compounds
- G03C7/382—Heterocyclic compounds with two heterocyclic rings
- G03C7/3825—Heterocyclic compounds with two heterocyclic rings the nuclei containing only nitrogen as hetero atoms
- G03C7/3835—Heterocyclic compounds with two heterocyclic rings the nuclei containing only nitrogen as hetero atoms four nitrogen atoms
Landscapes
- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- Silver Salt Photography Or Processing Solution Therefor (AREA)
Description
ïŒç£æ¥äžã®å©çšåéïŒ
æ¬çºæã¯ãé«çºè²æ§ã§ãä¿åæ§ãç¹ã«èå
æ§ã®
æ¹è¯ãããããŒã³ã¿è²çŽ ç»åã圢æãããšããã®
ããŒã³ã¿ã«ãã©ãŒãå«æããããã²ã³åéã«ã©ãŒ
åçæå ææã«é¢ãããæŽã«è©³ããã¯æ°èŠãª1H
âãã©ãŸãïŒïŒïŒâââããªã¢ãŸãŒã«ç³»
ããŒã³ã¿ã«ãã©ãŒãå«æããããã²ã³åéã«ã©ãŒ
åçæå ææã«é¢ããã ïŒåŸæ¥æè¡ïŒ éåžžãããã²ã³åéã«ã©ãŒåçæå ææã«ãã
ãŠã¯ãé²å ãããããã²ã³åéç²åãè³éŠæ第ïŒ
çŽã¢ãã³ç³»çºè²çŸåäž»è¬ã«ããéå ãããã®éç
æãããåèšçºè²çŸåäž»è¬ã®é žåäœãšã€ãšããŒã
ããŒã³ã¿ããã³ã·ã¢ã³ã®åè²çŽ ã圢æããã«ãã©
ãŒãšã®ã«ãããªã³ã°ã«ããè²çŽ ç»åãåŸãããšã
ã§ããã åèšããŒã³ã¿è²çŽ ã圢æããçºã«ãåŸæ¥ããå®
çšã«äŸãããŠããã«ãã©ãŒã¯ãã©ãŸãã³åã«ãã©
ãŒã§ããããããã¯å¥œãŸãããªãå¯åžåãæãã
ãšå ±ã«ä¿åæ§ãç¹ã«ãã«ããªã³ã¬ã¹ã«å¯Ÿããèæ§
ïŒãã«ããªã³èæ§ïŒã«ä¹ãããšããæ¬ ç¹ãæããŠ
ããã äžèšæ¬ ç¹ãæ¹è¯ããããã«ãããŸã§çš®ã ã®1H
âãã©ãŸãïŒïŒïŒâââããªã¢ãŸãŒã«ç³»
ããŒã³ã¿ã«ãã©ãŒãææ¡ãããŠãããäŸãã°ãç±³
åœç¹èš±3725067å·ãè±åœç¹èš±1252418å·ãå
1334515å·ã«èšèŒãããŠããããããã®ç¹èš±ã«èš
èŒã®ååç©ãå¿è«ãå¯åžåãšããç¹ã§ã¯ãã©ãŸã
ã³ç³»ããŒã³ã¿ã«ãã©ãŒã«åªããããã«ããªã³èæ§
ã®æ¹è¯ã¯äžååã§ããããŸãçºè²æ§ç»åã®èå æ§
ãšããç¹ã§ã®æ¹è¯ã¯ã»ãšãã©ç€ºãããŠããªãã
Research Disclosare 12443èšèŒã®ååç©ãçºè²
æ§ãšããç¹ã§å šãå®çšã«äŸãåŸãªããç¹éæ58â
42045ã«èšèŒã®1Hâãã©ãŸãïŒïŒïŒââ
âããªã¢ãŸãŒã«åããŒã³ã¿ã«ãã©ãŒã¯ãã«ããªã³
èæ§ã®æ¹è¯åã³çºè²æ§ãšããç¹ã§ã¯èããæ¹è¯ã
ããŠãããããã¯ãèå æ§ã®æ¹è¯ã¯ã»ãšãã©ãªã
ããŠããªãã ãŸãç¹éæ59â99437å·ãå59â125732å·ã«èš
èŒã®ã«ãã©ãŒãçºè²æ§ã®æ¹è¯ã¯ãªãããŠãããã
èšèŒã«ãã©ãŒã«åºã¥ãè²çŽ ç»åã®èå æ§ãšããç¹
ã§ã¯çžå€ããæ¹è¯ã®ããšãèŠãããªãã åŸè ã¯åã«äœµçšããæ·»å å€ã«ãã€ãŠç»åã®èå
æ§ãæ¹åãããŠããã«éããªãããã åè æ现æž
èšèŒååç©äŸ19ã®ã«ãã©ãŒã¯ããããã«èå æ§ã¯
æ¹è¯ãããŠãããååãšã¯èšããªãã ããªãã¡ããããŸã§å¯åžåããªãããã«ããªã³
èæ§ãé«ããšããããšã§æ³šç®ãããŠãã1Hâã
ã©ãŸãïŒïŒïŒâââããªã¢ãŸã«ç³»ããŒã³
ã¿ã«ãã©ãŒãè²çŽ ç»åã®èå æ§ã«ã€ããŠã¯ã»ãšã
ã©æ¹è¯ããªãããŠããŠããªããšèšããã ïŒçºæã®ç®çïŒ æ¬çºæã®ç®çã¯ãèå æ§åã³ãã«ããªã³èæ§ã
ããããããçºè²æ§ã®é«ãããã²ã³åéã«ã©ãŒå
çæå ææãæäŸããããšã«ããã ïŒçºæã®æ§æïŒ åèšããæ¬çºæã®ç®çã¯ãæ¯æäœäžã«å°ããšã
äžå±€ã®ããã²ã³åéä¹³å€å±€ãæããããã²ã³åé
ã«ã©ãŒåçæå ææã«ãããŠãåèšããã²ã³åé
ä¹³å€å±€äžã«äžèšäžè¬åŒã§ç€ºãããããŒã³ã¿ã«ãã©
ãŒã®å°ããšãäžã€ãå«æãããŠããããšãç¹åŸŽãš
ããããã²ã³åéã«ã©ãŒåçæå ææã«ãã€ãŠé
æãããã äžè¬åŒ åŒäžãR1ã¯ïŒçŽã¢ã«ãã«åºãR2ã¯ïŒçŽãŸãã¯
ïŒçŽã¢ã«ãã«åºãè¡šãããã¯çºè²çŸåäž»è¬ã®é ž
åäœãšåå¿ããŠé¢è±ããæ°ŽçŽ åå以å€ã®è±é¢åºã
è¡šããã 次ã«æ¬çºæã詳现ã«èª¬æããã æ¬çºæè ãã¯ãåèšã®ç¹ãç®æããŠéæãç 究
ãããããŠããçµæããã«ããªã³èæ§ãè¯å¥œã§ç»
åã®èå æ§ããããããããé«ãçºè²æ§ã瀺ã
1Hâãã©ãŸãïŒïŒïŒâââããªã¢ãŸãŒã«
ç³»ããŒã³ã¿ã«ãã©ãŒãèŠåºãã«å°ã€ãã å ·äœçã«æ¬¡ã®äžè¬åŒã§ç€ºãããã äžèšäžè¬åŒã«æŒããŠãR1ã¯ïŒçŽã¢ã«ãã«ãR2
ã¯ïŒçŽãŸãã¯ïŒçŽã¢ã«ãã«ãè¡šãããã¯çºè²çŸ
å䞻系ã®é žåäœãšåå¿ããŠé¢è±ããæ°ŽçŽ åå以å€
ã®é¢è±åºãè¡šããã R1ã§ç€ºãããïŒçŽã¢ã«ãã«åºã®ïŒçŽççŽ ã¯ã¢
ã«ãã«ä»¥å€ã«ã¢ãªãŒã«ãäŸãã°ããšãã«æŽã«ã¯ã¢
ã«ã³ãã·ãªã©ã§çœ®æãããŠãããããŸãïŒçŽççŽ
ãå åããŠã·ã¯ãç°ã圢æããå Žåãå¿è«ïŒçŽã¢
ã«ãã«ã«å«ãŸãããèŠããã«ïŒçŽççŽ ã«æ°ŽçŽ 以å€
ãçµåããŠãããã¹ãŠãè¡šãããŠããããŸããïŒ
çŽççŽ ã«çµåããã¢ã«ãã«ã¯ããã²ã³ã¢ã«ã³ãã·
çã®çœ®æåºã§çœ®æãããŠãããã å ·äœçãªïŒçŽã¢ã«ãã«ãšããŠã¯ãïœâããã«ã
ïŒïŒïŒâãžã¡ãã«âïŒâã¡ããã·âãšãã«ãïŒïŒ
ïŒâãžã¡ãã«âïŒâã¯ããâãšãã«ãïŒâã¡ãã«
âïŒâã¡ããã·âãšãã«ãïŒâã¡ãã«âïŒâããš
ãã«âãšãã«ãïŒïŒïŒâãžâïœâã¢ãã«âããã·
ã«ãïŒïŒïŒâãžã¡ãã«ãã«ãã«ãã³âïŒâã€ã«ã
ïŒïŒïŒâãžã¡ãã«âããã«ãïŒâãšãã«âïŒâã¡
ãã«âãããã«ãã¢ããã³ãã«ãªã©ã代衚çã«æ
ããããã R2ã§ç€ºãããïŒçŽã¢ã«ãã«ã¯1Hâãã©ãŸã
ïŒïŒïŒâââããªã¢ãŸãŒã«ç°ã«çŽçµããæ ¹
å ççŽ ã«æ°ŽçŽ ïŒåãçµåããŠããã¢ã«ãã«ãè¡šã
ãïŒçŽã¢ã«ãã«ã¯æ ¹å ççŽ ã«æ°ŽçŽ ãå šãçµåããŠ
ããªãã¢ã«ãã«ãè¡šããã R2ã§ç€ºãããïŒçŽãïŒçŽã®ã¢ã«ãã«ã¯ã¢ãªãŒ
ã«ããããç°ãããã²ã³ãã·ã¢ãæŽã«ã¢ã«ã³ãã·
ã«ã«ããã«ãã¢ã·ã«ãã«ã«ããã€ã«çã§ç€ºããã
ã«ã«ããã«ã§çµåãã眮æåºãæŽã«ã¯ããããã¢
ã«ã³ãã·ãã¢ã«ãã«ããªãã¢ãªãŒã«ããªãã¢ã«ã
ã«ã¹ã«ããã«ãã¢ãªãŒã«ã¹ã«ããã«ãã¢ã«ãã«ã¹
ã«ãã€ãã«ãã¢ãªãŒã«ã¹ã«ãã€ãã«ããžã¢ã«ãã«
ã¢ããçã®ãããååã§çµåãã眮æåºã§çœ®æã
ããŠãããããããã®çœ®æåºã®äžã§ç¹ã«å¥œããã
ã®ã¯ã¢ã«ãã«ããªãã¢ãªãŒã«ããªãã¢ã«ãã«ã¹ã«
ããã«ãã¢ãªãŒã«ã¹ã«ããã«ãã¢ã«ãã«ã¹ã«ãã€
ãã«ãã¢ãªãŒã«ã¹ã«ãã€ãã«ããéžã°ãããã®ã§
ããã å°ããããç°åºã1Hâãã©ãŸãïŒïŒïŒâ
ââããªã¢ãŸãŒã«âïŒâã€ã«ç³»ååç©ã®æãã¹
åã®1Hâãã©ãŸãïŒïŒïŒâââããªã¢ãŸ
ãŒã«ç³»ååç©ã圢æããããå¿è«æ¬çºæã«å åã
ããããŒã³ã¿ã«ãã©ãŒã§ããã ã§è¡šããããé¢è±åºã¯ããã²ã³ãæŽã«ã¯é žçŽ
ååãçªçŽ ååãŸãã¯ã€ãªãŠååã§ã«ãããªã³ã°
äœã«çµåããŠããææ©åºãè¡šããã é žçŽ ååã§ã«ãããªã³ã°äœã«çµåããŠããé¢è±
åºãšããŠã¯ã¢ã«ã³ãã·ãã¢ãªãŒã«ãªãã·ãã¢ã·ã«
ãªãã·ããããç°ãªãã·ãªã©ãæããããçªçŽ å
åã§ã«ãããªã³ã°äœã«çµåããŠããé¢è±åºãšããŠ
ã¯ã¢ã·ã«ã¢ããããžã¢ã·ã«ã¢ãããã¹ã«ãã³ã¢ã
ãåã³ãã®çªçŽ ååãå«ãïŒå¡ãŸãã¯ïŒå¡ã®è€çŽ
ç°åºãªã©ãæããããæŽã«ã€ãªãŠååã§ã«ãããª
ã³ã°äœã«çµåããŠããé¢è±åºãšããŠã¯ããªãã¢
ããã¢ã«ãã«ããªãã¢ãªãŒã«ããªããããç°ã
ãªãã¢ãªãŒã«ã¹ã«ããã«ãã¢ã«ãã«ã¹ã«ããã«ãª
ã©ãæããããã 以äžã«æ¬çºæã«åºã¥ãå ·äœçäŸç€ºã瀺ãããæ¬
çºæã¯ãããã«éå®ããããã®ã§ã¯ãªãã 次ã«ããã®åææ³ãèšèŒããããResearch
Disclosare 12443ç±³åœç¹èš±3725067å·ãç¹éæ59
â99437çãåèã«ããŠåæãè¡ã€ãã ååç©äŸ(1)ã®åæ åå¿ã¹ããŒã ãèšããšä»¥äžã®ããã«ãªãã ïŒïŒã®åæ ïŒâã¡ãã«âïŒâãªã¯ã¿ãã·ã«ã¹ã«ããã«âã
ãããªã³é ž70ïœãšããªã«ã«ãããã©ãžã10ïœãã¡
ãã«ãœã«ãœã«ãäžïŒæéç ®æ²žéæµãããå·åŸæåº
ããçµæ¶ãåããã¢ã«ã³ãŒã«ïŒæ°Žã®æ··å溶åªã«
ãŠåçµæ¶ãç®çç©ãåŸãã ïŒïŒã®åæ 8.8ïœã®ïŒïŒåã³3.6ïœã®ïœâããã«âããã¢
ã¡ãã«ã±ãã³ã200mlã®ã¢ã«ã³ãŒã«äžã«ãŠãïŒæ
éç ®æ²žæªæãããåå¿æ¶²ãå·åŽãæåºããçµæ¶ã
åãããåããçµæ¶ãã¡ã¿ããŒã«ã«æº¶è§£ã10
ïŒ çé žãœãŒãã«ãŠPHïŒãšãããããã§æåºããçµ
æ¶ãåãååæ°ŽæŽãããçµæ¶ãå°éã®æ°Žãå«ã
ã¢ã«ã³ãŒã«ã«ãŠåçµæ¶ããç®çã®ïŒïŒãåŸãã ïŒïŒã®åæ ïŒïœã®ïŒïŒã500mlã®ïœâããã«ã³ã«ãŠåæ£
ããçªçŽ ã¬ã¹ãéããŠïŒæéç ®æ²žæªæãããæŸå·
åŸæåºããåºäœãåããã¢ã»ããããªã«ããå
çµæ¶ããã ïŒïŒã®åæ ïŒïœã®ïŒïŒãã¯ãããã«ã ã«æº¶è§£ããåœéã®
âã¯ãã«ã¹ã¯ã·ã³ã€ãããå ãã20âã«ä¿ã¡ãª
ãã30ååå¿ãããããã®åŸãåå¿æ¶²ãåžã¢ã«ã«
ãªã§æŽæµããŠçæããã³ãã¯é žã€ãããé€å»ã
ããã¯ãããã«ã ãçå»ããæ®æž£ã«ã€ããŠãã³ãŒ
ã³ïŒã¢ã»ãã³ãã·ãªã«ã²ã«ãæ äœãšããŠã«ã©ã ã¯
ãããè¡ããç®çç©ãåŸããïŒïŒå³ã¡ãäŸç€º(1)
ã®ç¢ºèªã¯æ žç£æ°å ±é³Žã¹ãã¯ãã«ã«ãŠè¡ã€ãã é¢è±åºïŒžãé€ãä»ã®1Hâãã©ãŸãïŒïŒïŒâ
ââããªã¢ãŸãŒã«æ žãã®ãã®ã®åæã¯äŸç€º
(1)ã®æ¹æ³ã«æºããŠè¡ã€ãã ååç©äŸ(2)ã®åæ äŸç€º(1)ã«æŒããïŒïŒãäŸãã°ç±³åœç¹èš±
3725067å·ã®äŸâ49ã®æ¹æ³ã«åŸã€ãŠèçŽ åããã
ã®èçŽ çœ®æäœãšã¡ã¿ã³ã¹ã«ãã³é žã®éå¡©ãšãåå¿
ãããããšã«ããç®çç©ãåŸãããã äŸç€º(4)ã(10)ãïŒ17ïŒãïŒ18ïŒãïŒ19ïŒã«ã€ããŠã¯
ã
ã¹ãŠç¹éæ59â99437å·ã«èšèŒã®äžè¬åææ³ãå
èã«åæãç®çç©ãåŸãã æ¬çºæãçšããŠäœãããããã²ã³åéã«ã©ãŒå
çæå ææã«ã¯åŸæ¥ããçšããããŠããè²çŽ 圢æ
ã«ãã©ãŒãå«ãã§ããŠãããã é»è²çºè²ã«ãã©ãŒãšããŠã¯ãå ¬ç¥ã®ééã±ãã¡
ãã¬ã³ç³»ã«ãã©ãŒãçšããããšãã§ãããããã
ã®ãã¡ãã¹ã³ãŸã€ã«ã¢ã»ãã¢ããªãç³»åã³ããã
ã€ã«ã¢ã»ãã¢ããªãç³»ååç©ã¯æå©ã§ãããçšã
åŸãé»è²çºè²ã«ãã©ãŒã®å ·äœäŸã¯ç±³åœç¹èš±
2875057å·ãå3265506å·ãå3408194å·ãå
3551155å·ãå3582322å·ãå3725072å·ãå
3891445å·ã西ç¬ç¹èš±1547868å·ã西ç¬åºé¡å ¬é
2219917å·ãå2261361å·ãå2414006å·ãè±åœç¹
èš±1425020å·ãç¹å ¬æ51â10783å·ãç¹éæ47â
26133å·ãå48â73147å·ãå51â10236å·ãå50
â6341å·ãå50â123342å·ãå50â130442å·ãå
51â21827å·ãå50â87650å·ãå52â82424å·ã
å52â115219å·ãªã©ã«èšèŒããããã®ã§ããã ã·ã¢ã³çºè²ã«ãã©ãŒãšããŠã¯ãããšããŒã«ç³»å
åç©ãããããŒã«ç³»ååç©ãªã©ãçšããããšãã§
ããããã®å ·äœäŸã¯ç±³åœç¹èš±2369929å·ãå
2434272å·ãå2474293å·ãå2521908å·ãå
2895826å·ãå3034892å·ãå3311476å·ãå
3458315å·ãå3476563å·ãå3583971å·ãå
3591383å·ãå3767411å·ãå4004929å·ã西ç¬ç¹
èš±åºé¡ïŒOLSïŒ2414830å·ãå2454329å·ãç¹é
æ48â598338å·ãå51â26034å·ãå48â5055å·ã
å51â146828å·ãå52â69624å·ãå52â90932å·
ã«èšèŒã®ãã®ã§ããã ããŒã³ã¿çºè²ã«ãã©ãŒãšããŠã¯ãæ¬çºæã®ã«ã
ã©ãŒãåç¬ã§ããŸãã¯ïŒçš®ä»¥äžäœµçšããŠãããã€
ãããªããæŽã«åŸæ¥å ¬ç¥ã®ãã©ãŸãã³ç³»ååç©ã
ã€ã³ããŸãã³ç³»ååç©ãã·ã¢ãã¢ã»ãã«ç³»åå
ç©ããã©ãŸãªããã³ãã€ãããŸãŒã«ç³»ååç©ãã
ã©ãŸãããªã¢ãŸãŒã«ç³»ååç©ãªã©ãé©å®äœµçšããŠ
ãããŸããªããããããªããå°ããšãäžã€ã¯æ¬çº
æã®ã«ãã©ãŒã§ããã åãè²è£æ£å¹æãæããã«ã©ãŒãã»ã«ãã©ãŒã
æŽã«ã¯ç»è³ªåäžã®çºçŸåæå¶å€æŸåºã«ãã©ãŒïŒã
ãããDIRã«ãã©ãŒïŒãå¿ èŠã«å¿ããŠæ¬çºæã«ã
ã©ãŒãšå ±ã«çšããããšãåºæ¥ãã æ¬çºæã®ããŒã³ã¿ã»ã«ãã©ãŒåã³ãããšä¿ãå
ã«ãã©ãŒãããã²ã³åéä¹³å€å±€ã«å°å ¥ããã«ã¯å ¬
ç¥ã®æ¹æ³ãäŸãã°ç±³åœç¹èš±2322027å·ã«èšèŒã®æ¹
æ³ãªã©ãçšããããã ããšãã°ããã¿ãŒã«é žã¢ã«ãã«ãšã¹ãã«ïŒãžã
ãã«ãã¿ã¬ãŒãããžãªã¯ãã«ãã¿ã¬ãŒããªã©ïŒã
ãªã³é žãšã¹ãã«ïŒãžããšãã«ããªã¹ããšãŒããã
ãªããšãã«ããªã¹ããšãŒããããªã¯ã¬ãžã¬ã«ãªã¹
ããšãŒãããžãªã¯ãã«ããã«ãªã¹ããšãŒãïŒãã¯
ãšã³é žãšã¹ãã«ïŒããšãã°ã¢ã»ãã«ã¯ãšã³é žããª
ããã«ïŒãå®æ¯éŠé žãšã¹ãã«ïŒããšãã°å®æ¯éŠé ž
ãªã¯ãã«ïŒãã¢ã«ãã«ã¢ããïŒããšãã°ãžãšãã«
ã©ãŠãªã«ã¢ããïŒãèèªé žãšã¹ãã«é¡ïŒããšãã°
ãžãããã·ãšãã«ãµã¯ã·ããŒãããžãªã¯ãã«ã¢ã»
ã¬ãŒãïŒãããªã¡ã·ã³é žãšã¹ãã«é¡ïŒããšãã°ã
ãªã¡ã·ã³é žããªããã«ïŒãªã©ããŸãã¯æ²žç¹çŽ30â
ä¹è³150âã®ææ©æº¶åªãããšãã°é ¢é žãšãã«ãé ¢
é žããã«ã®ããšãäœçŽã¢ã«ãã«ã¢ã»ããŒãããã
ããªã³é žãšãã«ãïŒçŽããã«ã¢ã«ã³ãŒã«ãã¡ãã«
ã€ãœããã«ã±ãã³ãβâãšããã·ãšãã«ã¢ã»ããŒ
ããã¡ãã«ã»ã«ãœã«ãã¢ã»ããŒãçã«æº¶è§£ããã®
ã¡ã芪氎æ§ã³ãã€ãã«åæ£ããããäžèšã®é«æ²žç¹
ææ©æº¶åªãšäœæ²žç¹ææ©æº¶åªãšãæ··åããŠçšããŠã
ããã ãŸãç¹å ¬æ51â39853å·ãç¹éæ51â59943å·ã«
èšèŒãããŠããéåç©ã«ããåæ£æ³ã䜿çšããã
ãšãã§ããã æ¬çºæã®ããŒã³ã¿ã»ã«ãã©ãŒãããã²ã³åéä¹³
å€å±€äžã«æ·»å ããå Žåãéåžžããã²ã³åéïŒã¢ã«
åœã0.005ãïŒã¢ã«ããããã¯0.03ã0.5ã¢ã«ã®ç¯
å²ã§æ·»å ãããã æ¬çºæã®ããŒã³ã¿ã»ã«ãã©ãŒã«ãã圢æããã
è²çŽ ç»åèªèº«åŒ·ãèå æ§ã瀺ããã耪è²é²æ¢å€ã
䜵çšãããæŽã«ã¯çŽ«å€ç·åžåå€ãå«æããå±€ãäž
å±€ã«èšããããšã«ãã€ãŠæŽã«èå æ§ã¯åäžããã 耪è²é²æ¢å€ãšããŠã¯ãããšãã°ãç±³åœç¹èš±
2360290å·ãå2418613å·ãå2675314å·ãå
2701197å·ãå2704713å·ãå2728659å·ãå
2732300å·ãå2735765å·ãå2710801å·ãå
2816028å·ãè±åœç¹èš±1363921å·çã«èšèŒãããã
ã€ããããã³èªå°äœãç±³åœç¹èš±3457079å·ãå
3069262å·çã«èšèŒããã没é£åé žèªå°äœãç±³åœ
ç¹èš±2735765å·ãå3698909å·ãç¹å ¬æ49â20977
å·ãå52â6623å·ã«èšèŒãããïœâã¢ã«ã³ãã·ã
ãšããŒã«é¡ãç±³åœç¹èš±3432300å·ãå3573050å·ã
å3574627å·ãå3764337å·ãç¹éæ52â35633å·ã
å52â147434å·ãå52â152225å·ã«èšèŒãããïœ
âãªãã·ããšããŒã«èªå°äœãç±³åœç¹èš±3700455å·
ã«èšèŒã®ãã¹ããšããŒã«é¡çãããã 玫å€ç·åžåå€ãšããŠã¯ãäŸãã°ãã¢ãªãŒã«åºã§
眮æããããã³ãŸããªã¢ãŸãŒã«ååç©ïŒäŸãã°ã
ç±³åœç¹èš±3533794å·ã«èšèŒã®ãã®ïŒãïŒâãã¢ãŸãª
ãã³ååç©ïŒäŸãã°ãç±³åœç¹èš±3314794å·ãå
3352681å·ã«èšèŒã®ãã®ïŒããã³ãŸããšãã³ååç©
ïŒäŸãã°ãç¹éæ46â2784å·ã«èšèŒã®ãã®ïŒãã±ã€
ãé žãšã¹ãã«ååç©ïŒäŸãã°ãç±³åœç¹èš±3705805
å·ãå3707375å·ã«èšèŒã®ãã®ïŒããã¿ãžãšã³åå
ç©ïŒäŸãã°ãç±³åœç¹èš±4045229å·ã«èšèŒã®ãã®ïŒã
ãããã¯ããã³ãŸãªãã·ããŒã«ååç©ïŒäŸãã°ã
ç±³åœç¹èš±3700455å·ã«èšèŒã®ãã®ïŒãçšããããš
ãã§ãããããã«ãç±³åœç¹èš±3499762å·ãç¹éæ
54â48535å·ã«èšèŒã®ãã®ãçšããããšãã§ããã æ¬çºæã«äœ¿çšãããããã²ã³åéä¹³å€ã«çšãã
ããããã²ã³åéãšããŠã¯ãèåéãå¡©åéãæ²
èåéãå¡©èåéãå¡©æ²èåéçã®éåžžã®ããã²
ã³åéä¹³å€ã«äœ¿çšãããä»»æã®ãã®ãå«ãŸããã
æ¬çºæã«äœ¿çšãããããã²ã³åéã¯å¿ èŠãªæå æ³¢
é·åã«æå æ§ãä»äžããããã«ãé©åœãªå¢æè²çŽ
ã®éžæã«ããåå å¢æããªããããçšããããè²
çŽ ã«ã¯ã·ã¢ãã³è²çŽ ãã¡ãã·ã¢ãã³è²çŽ ãè€åã·
ã¢ãã³è²çŽ ãè€åã¡ãã·ã¢ãã³è²çŽ ãããããŒã©
ãŒã·ã¢ãã³è²çŽ ãããã·ã¢ãã³è²çŽ ãã¹ããªã«è²
çŽ åã³ãã·ãªããœããŒã«è²çŽ ãå å«ãããã æçšãªå¢æè²çŽ ãšããŠã¯ãäŸãã°ããã€ãç¹èš±
929080å·ãç±³åœç¹èš±2231658å·ãå2493748å·ãå
2503776å·ãå2519001å·ãå2912329å·ãå
3656959å·ãå3672897å·ãå3694217å·ãå
4025349å·ãå4046572å·ãè±åœç¹èš±1242588å·ã
ç¹å ¬æ44â14030å·ãå52â24844å·ã«èšèŒããã
ãã®ãæããããšãåºæ¥ãã ãããã®å¢æè²çŽ ã¯åç¬ã«çšããŠãããããã
ããã®çµåããçšããŠããããå¢æè²çŽ ã®çµåã
ã¯ç¹ã«ã匷è²å¢æã®ç®çã§ãã°ãã°çšããããã
ãã®ä»£è¡šäŸã¯ç±³åœç¹èš±2688545å·ãå2977229å·ã
å3397060å·ãå3522052å·ãå3527641å·ãå
3617293å·ãå3628964å·ãå3666480å·ãå
3672898å·ãå3679428å·ãå3703377å·ãå
3769301å·ãå3814609å·ãå3837862å·ãå
4026707å·ãè±åœç¹èš±1344281å·ãå1507803å·ã
ç¹å ¬æ43â4936å·ãå53â12375å·ãç¹éæ52â
110618å·ãå52â109925å·ã«èšèŒãããŠããã ãŸããæ¬çºæã«äœ¿çšãããããã²ã³åéä¹³å€
ã¯ãçš®ã ã®å ¬ç¥ã®åççšæ·»å å€ãå«æãããããš
ãåºæ¥ããäŸãã°Research Disclosave 17643ã«
èšèŒãããŠãããåŠãåççšæ·»å å€ã§ããã æ¬çºæããã²ã³åéåçæå ææã®æ¯æäœãšã
ãŠã¯ãã©ã¹ããã¯ãã€ã«ã ããã©ã¹ããã¯ã©ãã
ãŒãçŽããã©ã€ã¿çŽãåæçŽçãåŸæ¥ç¥ãããã
ã®ã䜿çšç®çã«å¿ããŠé©å®éžæããã°ããã ãŸããæ¬çºæã®ããã²ã³åéã«ã©ãŒåçæå æ
æã¯åœæ¥çã«æŒãŠçšããããä»»æã®æ§æãæ¡ãã
ãšãã§ããã ããããŠæ§æãããæ¬çºæã®ããã²ã³åéã«ã©
ãŒåçæå ææã¯ãé²å ããåŸçºè²çŸååŠçãšã
ãŠçš®ã ã®åçåŠçæ¹æ³ãçšããããã æ¬çºæã«ãããŠçºè²çŸå液ã«äœ¿çšãããè³éŠæ
第ïŒçŽã¢ãã³çºè²çŸåäž»è¬ã¯çš®ã ã®ã«ã©ãŒåçã
ãã»ã¹ã«ãããŠåºç¯å²ã«äœ¿çšãããŠããå ¬ç¥ã®ã
ã®ãå å«ãããããããã®çŸåå€ã¯ã¢ããããšã
ãŒã«ç³»ããã³ïœâããšãã¬ã³ãžã¢ãã³ç³»èªå°äœã
å«ãŸããããããã®ååç©ã¯éé¢ç¶æ ããå®å®ã®
ããäžè¬ã«å¡©ã®åœ¢ãäŸãã°å¡©é žå¡©ãŸãã¯ç¡«é žå¡©ã®
圢ã§äœ¿çšãããããŸããããã®ååç©ã¯ãäžè¬ã«
çºè²çŸå液ïŒã«ã€ããŠçŽ0.1ïœãçŽ30ïœã®æ¿åºŠã
奜ãŸããã¯çºè²çŸå液ïŒã«ã€ããŠçŽïŒïœãçŽ
1.5ïœã®æ¿åºŠã§äœ¿çšããã ã¢ããããšããŒã«ç³»çŸåå€ãšããŠã¯ãäŸãã°ïœ
âã¢ããããšããŒã«ãïœâã¢ããããšããŒã«ãïŒ
âã¢ããâïŒâãªãã·ãã«ãšã³ãïŒâã¢ããâïŒ
âãªãã·ãã«ãšã³ãïŒâãªãã·âïŒâã¢ããâ
ïŒïŒïŒâãžã¡ãã«ãã³ãŒã³ãªã©ãå«ãŸããã ç¹ã«æçšãªç¬¬ïŒçŽè³éŠæã¢ããç³»çºè²çŸåå€ã¯
ïŒNâ²âãžã¢ã«ãã«âïœâããšãã¬ã³ãžã¢ãã³
ç³»ååç©ã§ãããã¢ã«ãã«åºããã³ããšãã«åºã¯
ä»»æã®çœ®æåºã§çœ®æãããŠããŠãããããã®äžã§
ãç¹ã«æçšãªååç©äŸãšããŠã¯ïŒ®ïŒNâ²âãžãšã
ã«âïœâããšãã¬ã³ãžã¢ãã³å¡©é žå¡©ãâã¡ãã«
âïœâããšãã¬ã³ãžã¢ãã³å¡©é žå¡©ãïŒNâ²âãž
ã¡ãã«âïœâããšãã¬ã³ãžã¢ãã³å¡©é žå¡©ãïŒâã¢
ããâïŒâïŒïŒ®âãšãã«ââããã·ã«ã¢ããïŒâ
ãã«ãšã³ãâãšãã«ââβâã¡ã¿ã³ã¹ã«ãã³
ã¢ãããšãã«âïŒâã¡ãã«âïŒâã¢ããã¢ããªã³
ç¡«é žå¡©ãâãšãã«ââβâããããã·ãšãã«
ã¢ããã¢ããªã³ãïŒâã¢ããâïŒâã¡ãã«âïŒ
Nâ²âãžãšãã«ã¢ããªã³ãïŒâã¢ããââïŒïŒâ
ã¡ããã·ãšãã«ïŒââãšãã«âïŒâã¡ãã«ã¢ã
ãªã³âïœâãã«ãšã³ã¹ã«ãããŒããªã©ãæããã
ãšãã§ããã æ¬çºæã®åŠçã«ãããŠäœ¿çšãããçºè²çŸå液ã«
ã¯ãåèšç¬¬ïŒçŽè³éŠæã¢ãã³ç³»çºè²çŸåå€ã«å ã
ãŠæŽã«çºè²çŸå液ã«éåžžæ·»å ãããŠããçš®ã ã®æ
åãäŸãã°æ°Žé žåãããªãŠã ãçé žãããªãŠã ã
çé žã«ãªãŠã ãªã©ã®ã¢ã«ã«ãªå€ãã¢ã«ã«ãªéå±äº
ç¡«é žå¡©ãã¢ã«ã«ãªéå±éäºç¡«é žå¡©ãã¢ã«ã«ãªéå±
ããªã·ã¢ã³é žå¡©ãã¢ã«ã«ãªéå±ããã²ã³åç©ãã
ã³ãžã«ã¢ã«ã³ãŒã«ãæ°Žè»åå€ããã³æ¿ååå€ãªã©
ãä»»æã«å«æããããããšãã§ããããã®çºè²çŸ
å液ã®PHå€ã¯ãéåžžïŒä»¥äžã§ãããæãäžè¬çã«
ã¯çŽ10ãçŽ13ã§ããã æ¬çºæã«ãããŠã¯ãçºè²çŸååŠçããåŸãå®ç
èœãæããåŠç液ã§åŠçãããã該å®çèœãæã
ãåŠç液ã¯å®ç液ã§ããå Žåããã®åã«æŒçœåŠç
ãè¡ãããã該æŒçœå·¥çšã«çšããæŒçœæ¶²ãããã¯
æŒçœå®ç液ã«ãããŠäœ¿çšãããæŒçœå€ãšããŠã¯æ
æ©é žã®éå±é¯å¡©ãçšãããã該éå±é¯å¡©ã¯ãçŸå
ã«ãã€ãŠçæããéå±éãé žåããŠããã²ã³åé
ã«ããããšåæã«çºè²å€ã®æªçºè²éšãçºè²ããã
äœçšãæãããã®ã§ããã®æ§é ã¯ã¢ããããªã«ã«
ãã³é žãŸãã¯èé žãã¯ãšã³é žçã®ææ©é žã§éãã³
ãã«ããé çã®éå±ã€ãªã³ãé äœãããã®ã§ã
ãããã®ãããªææ©é žã®éå±é¯å¡©ã圢æãããã
ã«çšããããæã奜ãŸããææ©é žãšããŠã¯ãããª
ã«ã«ãã³é žãŸãã¯ã¢ããããªã«ã«ãã³é žãæãã
ããããããã®ããªã«ã«ãã³é žãŸãã¯ã¢ããããª
ã«ã«ãã³é žã¯ã¢ã«ã«ãªéå±å¡©ãã¢ã³ã¢ããŠã å¡©ã
ããã¯æ°Žæº¶æ§ã¢ãã³å¡©ã§ãã€ãŠãããã ãããã®å ·äœç代衚äŸãšããŠã¯æ¬¡ã®ãã®ãæã
ãããšãã§ããã ãïŒã ãšãã¬ã³ãžã¢ãã³ããã©é ¢é ž ãïŒã ãžãšãã¬ã³ããªã¢ãã³ãã³ã¿é ¢é ž ãïŒã ãšãã¬ã³ãžã¢ãã³ââïŒÎ²âãªãã·ãš
ãã«ïŒâïŒNâ²ïŒNâ²âããªé ¢é ž ãïŒã ãããã¬ã³ãžã¢ãã³ããã©é ¢é ž ãïŒã ãããªãããªé ¢é ž ãïŒã ãžã¯ããããµã³ãžã¢ãã³ããã©é ¢é ž ãïŒã ã€ãããžé ¢é ž ãïŒã ãžããããã·ãšãã«ã°ãªã·ã³ã¯ãšã³é ž
ïŒãŸãã¯é ç³é žïŒ
æ¹è¯ãããããŒã³ã¿è²çŽ ç»åã圢æãããšããã®
ããŒã³ã¿ã«ãã©ãŒãå«æããããã²ã³åéã«ã©ãŒ
åçæå ææã«é¢ãããæŽã«è©³ããã¯æ°èŠãª1H
âãã©ãŸãïŒïŒïŒâââããªã¢ãŸãŒã«ç³»
ããŒã³ã¿ã«ãã©ãŒãå«æããããã²ã³åéã«ã©ãŒ
åçæå ææã«é¢ããã ïŒåŸæ¥æè¡ïŒ éåžžãããã²ã³åéã«ã©ãŒåçæå ææã«ãã
ãŠã¯ãé²å ãããããã²ã³åéç²åãè³éŠæ第ïŒ
çŽã¢ãã³ç³»çºè²çŸåäž»è¬ã«ããéå ãããã®éç
æãããåèšçºè²çŸåäž»è¬ã®é žåäœãšã€ãšããŒã
ããŒã³ã¿ããã³ã·ã¢ã³ã®åè²çŽ ã圢æããã«ãã©
ãŒãšã®ã«ãããªã³ã°ã«ããè²çŽ ç»åãåŸãããšã
ã§ããã åèšããŒã³ã¿è²çŽ ã圢æããçºã«ãåŸæ¥ããå®
çšã«äŸãããŠããã«ãã©ãŒã¯ãã©ãŸãã³åã«ãã©
ãŒã§ããããããã¯å¥œãŸãããªãå¯åžåãæãã
ãšå ±ã«ä¿åæ§ãç¹ã«ãã«ããªã³ã¬ã¹ã«å¯Ÿããèæ§
ïŒãã«ããªã³èæ§ïŒã«ä¹ãããšããæ¬ ç¹ãæããŠ
ããã äžèšæ¬ ç¹ãæ¹è¯ããããã«ãããŸã§çš®ã ã®1H
âãã©ãŸãïŒïŒïŒâââããªã¢ãŸãŒã«ç³»
ããŒã³ã¿ã«ãã©ãŒãææ¡ãããŠãããäŸãã°ãç±³
åœç¹èš±3725067å·ãè±åœç¹èš±1252418å·ãå
1334515å·ã«èšèŒãããŠããããããã®ç¹èš±ã«èš
èŒã®ååç©ãå¿è«ãå¯åžåãšããç¹ã§ã¯ãã©ãŸã
ã³ç³»ããŒã³ã¿ã«ãã©ãŒã«åªããããã«ããªã³èæ§
ã®æ¹è¯ã¯äžååã§ããããŸãçºè²æ§ç»åã®èå æ§
ãšããç¹ã§ã®æ¹è¯ã¯ã»ãšãã©ç€ºãããŠããªãã
Research Disclosare 12443èšèŒã®ååç©ãçºè²
æ§ãšããç¹ã§å šãå®çšã«äŸãåŸãªããç¹éæ58â
42045ã«èšèŒã®1Hâãã©ãŸãïŒïŒïŒââ
âããªã¢ãŸãŒã«åããŒã³ã¿ã«ãã©ãŒã¯ãã«ããªã³
èæ§ã®æ¹è¯åã³çºè²æ§ãšããç¹ã§ã¯èããæ¹è¯ã
ããŠãããããã¯ãèå æ§ã®æ¹è¯ã¯ã»ãšãã©ãªã
ããŠããªãã ãŸãç¹éæ59â99437å·ãå59â125732å·ã«èš
èŒã®ã«ãã©ãŒãçºè²æ§ã®æ¹è¯ã¯ãªãããŠãããã
èšèŒã«ãã©ãŒã«åºã¥ãè²çŽ ç»åã®èå æ§ãšããç¹
ã§ã¯çžå€ããæ¹è¯ã®ããšãèŠãããªãã åŸè ã¯åã«äœµçšããæ·»å å€ã«ãã€ãŠç»åã®èå
æ§ãæ¹åãããŠããã«éããªãããã åè æ现æž
èšèŒååç©äŸ19ã®ã«ãã©ãŒã¯ããããã«èå æ§ã¯
æ¹è¯ãããŠãããååãšã¯èšããªãã ããªãã¡ããããŸã§å¯åžåããªãããã«ããªã³
èæ§ãé«ããšããããšã§æ³šç®ãããŠãã1Hâã
ã©ãŸãïŒïŒïŒâââããªã¢ãŸã«ç³»ããŒã³
ã¿ã«ãã©ãŒãè²çŽ ç»åã®èå æ§ã«ã€ããŠã¯ã»ãšã
ã©æ¹è¯ããªãããŠããŠããªããšèšããã ïŒçºæã®ç®çïŒ æ¬çºæã®ç®çã¯ãèå æ§åã³ãã«ããªã³èæ§ã
ããããããçºè²æ§ã®é«ãããã²ã³åéã«ã©ãŒå
çæå ææãæäŸããããšã«ããã ïŒçºæã®æ§æïŒ åèšããæ¬çºæã®ç®çã¯ãæ¯æäœäžã«å°ããšã
äžå±€ã®ããã²ã³åéä¹³å€å±€ãæããããã²ã³åé
ã«ã©ãŒåçæå ææã«ãããŠãåèšããã²ã³åé
ä¹³å€å±€äžã«äžèšäžè¬åŒã§ç€ºãããããŒã³ã¿ã«ãã©
ãŒã®å°ããšãäžã€ãå«æãããŠããããšãç¹åŸŽãš
ããããã²ã³åéã«ã©ãŒåçæå ææã«ãã€ãŠé
æãããã äžè¬åŒ åŒäžãR1ã¯ïŒçŽã¢ã«ãã«åºãR2ã¯ïŒçŽãŸãã¯
ïŒçŽã¢ã«ãã«åºãè¡šãããã¯çºè²çŸåäž»è¬ã®é ž
åäœãšåå¿ããŠé¢è±ããæ°ŽçŽ åå以å€ã®è±é¢åºã
è¡šããã 次ã«æ¬çºæã詳现ã«èª¬æããã æ¬çºæè ãã¯ãåèšã®ç¹ãç®æããŠéæãç 究
ãããããŠããçµæããã«ããªã³èæ§ãè¯å¥œã§ç»
åã®èå æ§ããããããããé«ãçºè²æ§ã瀺ã
1Hâãã©ãŸãïŒïŒïŒâââããªã¢ãŸãŒã«
ç³»ããŒã³ã¿ã«ãã©ãŒãèŠåºãã«å°ã€ãã å ·äœçã«æ¬¡ã®äžè¬åŒã§ç€ºãããã äžèšäžè¬åŒã«æŒããŠãR1ã¯ïŒçŽã¢ã«ãã«ãR2
ã¯ïŒçŽãŸãã¯ïŒçŽã¢ã«ãã«ãè¡šãããã¯çºè²çŸ
å䞻系ã®é žåäœãšåå¿ããŠé¢è±ããæ°ŽçŽ åå以å€
ã®é¢è±åºãè¡šããã R1ã§ç€ºãããïŒçŽã¢ã«ãã«åºã®ïŒçŽççŽ ã¯ã¢
ã«ãã«ä»¥å€ã«ã¢ãªãŒã«ãäŸãã°ããšãã«æŽã«ã¯ã¢
ã«ã³ãã·ãªã©ã§çœ®æãããŠãããããŸãïŒçŽççŽ
ãå åããŠã·ã¯ãç°ã圢æããå Žåãå¿è«ïŒçŽã¢
ã«ãã«ã«å«ãŸãããèŠããã«ïŒçŽççŽ ã«æ°ŽçŽ 以å€
ãçµåããŠãããã¹ãŠãè¡šãããŠããããŸããïŒ
çŽççŽ ã«çµåããã¢ã«ãã«ã¯ããã²ã³ã¢ã«ã³ãã·
çã®çœ®æåºã§çœ®æãããŠãããã å ·äœçãªïŒçŽã¢ã«ãã«ãšããŠã¯ãïœâããã«ã
ïŒïŒïŒâãžã¡ãã«âïŒâã¡ããã·âãšãã«ãïŒïŒ
ïŒâãžã¡ãã«âïŒâã¯ããâãšãã«ãïŒâã¡ãã«
âïŒâã¡ããã·âãšãã«ãïŒâã¡ãã«âïŒâããš
ãã«âãšãã«ãïŒïŒïŒâãžâïœâã¢ãã«âããã·
ã«ãïŒïŒïŒâãžã¡ãã«ãã«ãã«ãã³âïŒâã€ã«ã
ïŒïŒïŒâãžã¡ãã«âããã«ãïŒâãšãã«âïŒâã¡
ãã«âãããã«ãã¢ããã³ãã«ãªã©ã代衚çã«æ
ããããã R2ã§ç€ºãããïŒçŽã¢ã«ãã«ã¯1Hâãã©ãŸã
ïŒïŒïŒâââããªã¢ãŸãŒã«ç°ã«çŽçµããæ ¹
å ççŽ ã«æ°ŽçŽ ïŒåãçµåããŠããã¢ã«ãã«ãè¡šã
ãïŒçŽã¢ã«ãã«ã¯æ ¹å ççŽ ã«æ°ŽçŽ ãå šãçµåããŠ
ããªãã¢ã«ãã«ãè¡šããã R2ã§ç€ºãããïŒçŽãïŒçŽã®ã¢ã«ãã«ã¯ã¢ãªãŒ
ã«ããããç°ãããã²ã³ãã·ã¢ãæŽã«ã¢ã«ã³ãã·
ã«ã«ããã«ãã¢ã·ã«ãã«ã«ããã€ã«çã§ç€ºããã
ã«ã«ããã«ã§çµåãã眮æåºãæŽã«ã¯ããããã¢
ã«ã³ãã·ãã¢ã«ãã«ããªãã¢ãªãŒã«ããªãã¢ã«ã
ã«ã¹ã«ããã«ãã¢ãªãŒã«ã¹ã«ããã«ãã¢ã«ãã«ã¹
ã«ãã€ãã«ãã¢ãªãŒã«ã¹ã«ãã€ãã«ããžã¢ã«ãã«
ã¢ããçã®ãããååã§çµåãã眮æåºã§çœ®æã
ããŠãããããããã®çœ®æåºã®äžã§ç¹ã«å¥œããã
ã®ã¯ã¢ã«ãã«ããªãã¢ãªãŒã«ããªãã¢ã«ãã«ã¹ã«
ããã«ãã¢ãªãŒã«ã¹ã«ããã«ãã¢ã«ãã«ã¹ã«ãã€
ãã«ãã¢ãªãŒã«ã¹ã«ãã€ãã«ããéžã°ãããã®ã§
ããã å°ããããç°åºã1Hâãã©ãŸãïŒïŒïŒâ
ââããªã¢ãŸãŒã«âïŒâã€ã«ç³»ååç©ã®æãã¹
åã®1Hâãã©ãŸãïŒïŒïŒâââããªã¢ãŸ
ãŒã«ç³»ååç©ã圢æããããå¿è«æ¬çºæã«å åã
ããããŒã³ã¿ã«ãã©ãŒã§ããã ã§è¡šããããé¢è±åºã¯ããã²ã³ãæŽã«ã¯é žçŽ
ååãçªçŽ ååãŸãã¯ã€ãªãŠååã§ã«ãããªã³ã°
äœã«çµåããŠããææ©åºãè¡šããã é žçŽ ååã§ã«ãããªã³ã°äœã«çµåããŠããé¢è±
åºãšããŠã¯ã¢ã«ã³ãã·ãã¢ãªãŒã«ãªãã·ãã¢ã·ã«
ãªãã·ããããç°ãªãã·ãªã©ãæããããçªçŽ å
åã§ã«ãããªã³ã°äœã«çµåããŠããé¢è±åºãšããŠ
ã¯ã¢ã·ã«ã¢ããããžã¢ã·ã«ã¢ãããã¹ã«ãã³ã¢ã
ãåã³ãã®çªçŽ ååãå«ãïŒå¡ãŸãã¯ïŒå¡ã®è€çŽ
ç°åºãªã©ãæããããæŽã«ã€ãªãŠååã§ã«ãããª
ã³ã°äœã«çµåããŠããé¢è±åºãšããŠã¯ããªãã¢
ããã¢ã«ãã«ããªãã¢ãªãŒã«ããªããããç°ã
ãªãã¢ãªãŒã«ã¹ã«ããã«ãã¢ã«ãã«ã¹ã«ããã«ãª
ã©ãæããããã 以äžã«æ¬çºæã«åºã¥ãå ·äœçäŸç€ºã瀺ãããæ¬
çºæã¯ãããã«éå®ããããã®ã§ã¯ãªãã 次ã«ããã®åææ³ãèšèŒããããResearch
Disclosare 12443ç±³åœç¹èš±3725067å·ãç¹éæ59
â99437çãåèã«ããŠåæãè¡ã€ãã ååç©äŸ(1)ã®åæ åå¿ã¹ããŒã ãèšããšä»¥äžã®ããã«ãªãã ïŒïŒã®åæ ïŒâã¡ãã«âïŒâãªã¯ã¿ãã·ã«ã¹ã«ããã«âã
ãããªã³é ž70ïœãšããªã«ã«ãããã©ãžã10ïœãã¡
ãã«ãœã«ãœã«ãäžïŒæéç ®æ²žéæµãããå·åŸæåº
ããçµæ¶ãåããã¢ã«ã³ãŒã«ïŒæ°Žã®æ··å溶åªã«
ãŠåçµæ¶ãç®çç©ãåŸãã ïŒïŒã®åæ 8.8ïœã®ïŒïŒåã³3.6ïœã®ïœâããã«âããã¢
ã¡ãã«ã±ãã³ã200mlã®ã¢ã«ã³ãŒã«äžã«ãŠãïŒæ
éç ®æ²žæªæãããåå¿æ¶²ãå·åŽãæåºããçµæ¶ã
åãããåããçµæ¶ãã¡ã¿ããŒã«ã«æº¶è§£ã10
ïŒ çé žãœãŒãã«ãŠPHïŒãšãããããã§æåºããçµ
æ¶ãåãååæ°ŽæŽãããçµæ¶ãå°éã®æ°Žãå«ã
ã¢ã«ã³ãŒã«ã«ãŠåçµæ¶ããç®çã®ïŒïŒãåŸãã ïŒïŒã®åæ ïŒïœã®ïŒïŒã500mlã®ïœâããã«ã³ã«ãŠåæ£
ããçªçŽ ã¬ã¹ãéããŠïŒæéç ®æ²žæªæãããæŸå·
åŸæåºããåºäœãåããã¢ã»ããããªã«ããå
çµæ¶ããã ïŒïŒã®åæ ïŒïœã®ïŒïŒãã¯ãããã«ã ã«æº¶è§£ããåœéã®
âã¯ãã«ã¹ã¯ã·ã³ã€ãããå ãã20âã«ä¿ã¡ãª
ãã30ååå¿ãããããã®åŸãåå¿æ¶²ãåžã¢ã«ã«
ãªã§æŽæµããŠçæããã³ãã¯é žã€ãããé€å»ã
ããã¯ãããã«ã ãçå»ããæ®æž£ã«ã€ããŠãã³ãŒ
ã³ïŒã¢ã»ãã³ãã·ãªã«ã²ã«ãæ äœãšããŠã«ã©ã ã¯
ãããè¡ããç®çç©ãåŸããïŒïŒå³ã¡ãäŸç€º(1)
ã®ç¢ºèªã¯æ žç£æ°å ±é³Žã¹ãã¯ãã«ã«ãŠè¡ã€ãã é¢è±åºïŒžãé€ãä»ã®1Hâãã©ãŸãïŒïŒïŒâ
ââããªã¢ãŸãŒã«æ žãã®ãã®ã®åæã¯äŸç€º
(1)ã®æ¹æ³ã«æºããŠè¡ã€ãã ååç©äŸ(2)ã®åæ äŸç€º(1)ã«æŒããïŒïŒãäŸãã°ç±³åœç¹èš±
3725067å·ã®äŸâ49ã®æ¹æ³ã«åŸã€ãŠèçŽ åããã
ã®èçŽ çœ®æäœãšã¡ã¿ã³ã¹ã«ãã³é žã®éå¡©ãšãåå¿
ãããããšã«ããç®çç©ãåŸãããã äŸç€º(4)ã(10)ãïŒ17ïŒãïŒ18ïŒãïŒ19ïŒã«ã€ããŠã¯
ã
ã¹ãŠç¹éæ59â99437å·ã«èšèŒã®äžè¬åææ³ãå
èã«åæãç®çç©ãåŸãã æ¬çºæãçšããŠäœãããããã²ã³åéã«ã©ãŒå
çæå ææã«ã¯åŸæ¥ããçšããããŠããè²çŽ 圢æ
ã«ãã©ãŒãå«ãã§ããŠãããã é»è²çºè²ã«ãã©ãŒãšããŠã¯ãå ¬ç¥ã®ééã±ãã¡
ãã¬ã³ç³»ã«ãã©ãŒãçšããããšãã§ãããããã
ã®ãã¡ãã¹ã³ãŸã€ã«ã¢ã»ãã¢ããªãç³»åã³ããã
ã€ã«ã¢ã»ãã¢ããªãç³»ååç©ã¯æå©ã§ãããçšã
åŸãé»è²çºè²ã«ãã©ãŒã®å ·äœäŸã¯ç±³åœç¹èš±
2875057å·ãå3265506å·ãå3408194å·ãå
3551155å·ãå3582322å·ãå3725072å·ãå
3891445å·ã西ç¬ç¹èš±1547868å·ã西ç¬åºé¡å ¬é
2219917å·ãå2261361å·ãå2414006å·ãè±åœç¹
èš±1425020å·ãç¹å ¬æ51â10783å·ãç¹éæ47â
26133å·ãå48â73147å·ãå51â10236å·ãå50
â6341å·ãå50â123342å·ãå50â130442å·ãå
51â21827å·ãå50â87650å·ãå52â82424å·ã
å52â115219å·ãªã©ã«èšèŒããããã®ã§ããã ã·ã¢ã³çºè²ã«ãã©ãŒãšããŠã¯ãããšããŒã«ç³»å
åç©ãããããŒã«ç³»ååç©ãªã©ãçšããããšãã§
ããããã®å ·äœäŸã¯ç±³åœç¹èš±2369929å·ãå
2434272å·ãå2474293å·ãå2521908å·ãå
2895826å·ãå3034892å·ãå3311476å·ãå
3458315å·ãå3476563å·ãå3583971å·ãå
3591383å·ãå3767411å·ãå4004929å·ã西ç¬ç¹
èš±åºé¡ïŒOLSïŒ2414830å·ãå2454329å·ãç¹é
æ48â598338å·ãå51â26034å·ãå48â5055å·ã
å51â146828å·ãå52â69624å·ãå52â90932å·
ã«èšèŒã®ãã®ã§ããã ããŒã³ã¿çºè²ã«ãã©ãŒãšããŠã¯ãæ¬çºæã®ã«ã
ã©ãŒãåç¬ã§ããŸãã¯ïŒçš®ä»¥äžäœµçšããŠãããã€
ãããªããæŽã«åŸæ¥å ¬ç¥ã®ãã©ãŸãã³ç³»ååç©ã
ã€ã³ããŸãã³ç³»ååç©ãã·ã¢ãã¢ã»ãã«ç³»åå
ç©ããã©ãŸãªããã³ãã€ãããŸãŒã«ç³»ååç©ãã
ã©ãŸãããªã¢ãŸãŒã«ç³»ååç©ãªã©ãé©å®äœµçšããŠ
ãããŸããªããããããªããå°ããšãäžã€ã¯æ¬çº
æã®ã«ãã©ãŒã§ããã åãè²è£æ£å¹æãæããã«ã©ãŒãã»ã«ãã©ãŒã
æŽã«ã¯ç»è³ªåäžã®çºçŸåæå¶å€æŸåºã«ãã©ãŒïŒã
ãããDIRã«ãã©ãŒïŒãå¿ èŠã«å¿ããŠæ¬çºæã«ã
ã©ãŒãšå ±ã«çšããããšãåºæ¥ãã æ¬çºæã®ããŒã³ã¿ã»ã«ãã©ãŒåã³ãããšä¿ãå
ã«ãã©ãŒãããã²ã³åéä¹³å€å±€ã«å°å ¥ããã«ã¯å ¬
ç¥ã®æ¹æ³ãäŸãã°ç±³åœç¹èš±2322027å·ã«èšèŒã®æ¹
æ³ãªã©ãçšããããã ããšãã°ããã¿ãŒã«é žã¢ã«ãã«ãšã¹ãã«ïŒãžã
ãã«ãã¿ã¬ãŒãããžãªã¯ãã«ãã¿ã¬ãŒããªã©ïŒã
ãªã³é žãšã¹ãã«ïŒãžããšãã«ããªã¹ããšãŒããã
ãªããšãã«ããªã¹ããšãŒããããªã¯ã¬ãžã¬ã«ãªã¹
ããšãŒãããžãªã¯ãã«ããã«ãªã¹ããšãŒãïŒãã¯
ãšã³é žãšã¹ãã«ïŒããšãã°ã¢ã»ãã«ã¯ãšã³é žããª
ããã«ïŒãå®æ¯éŠé žãšã¹ãã«ïŒããšãã°å®æ¯éŠé ž
ãªã¯ãã«ïŒãã¢ã«ãã«ã¢ããïŒããšãã°ãžãšãã«
ã©ãŠãªã«ã¢ããïŒãèèªé žãšã¹ãã«é¡ïŒããšãã°
ãžãããã·ãšãã«ãµã¯ã·ããŒãããžãªã¯ãã«ã¢ã»
ã¬ãŒãïŒãããªã¡ã·ã³é žãšã¹ãã«é¡ïŒããšãã°ã
ãªã¡ã·ã³é žããªããã«ïŒãªã©ããŸãã¯æ²žç¹çŽ30â
ä¹è³150âã®ææ©æº¶åªãããšãã°é ¢é žãšãã«ãé ¢
é žããã«ã®ããšãäœçŽã¢ã«ãã«ã¢ã»ããŒãããã
ããªã³é žãšãã«ãïŒçŽããã«ã¢ã«ã³ãŒã«ãã¡ãã«
ã€ãœããã«ã±ãã³ãβâãšããã·ãšãã«ã¢ã»ããŒ
ããã¡ãã«ã»ã«ãœã«ãã¢ã»ããŒãçã«æº¶è§£ããã®
ã¡ã芪氎æ§ã³ãã€ãã«åæ£ããããäžèšã®é«æ²žç¹
ææ©æº¶åªãšäœæ²žç¹ææ©æº¶åªãšãæ··åããŠçšããŠã
ããã ãŸãç¹å ¬æ51â39853å·ãç¹éæ51â59943å·ã«
èšèŒãããŠããéåç©ã«ããåæ£æ³ã䜿çšããã
ãšãã§ããã æ¬çºæã®ããŒã³ã¿ã»ã«ãã©ãŒãããã²ã³åéä¹³
å€å±€äžã«æ·»å ããå Žåãéåžžããã²ã³åéïŒã¢ã«
åœã0.005ãïŒã¢ã«ããããã¯0.03ã0.5ã¢ã«ã®ç¯
å²ã§æ·»å ãããã æ¬çºæã®ããŒã³ã¿ã»ã«ãã©ãŒã«ãã圢æããã
è²çŽ ç»åèªèº«åŒ·ãèå æ§ã瀺ããã耪è²é²æ¢å€ã
䜵çšãããæŽã«ã¯çŽ«å€ç·åžåå€ãå«æããå±€ãäž
å±€ã«èšããããšã«ãã€ãŠæŽã«èå æ§ã¯åäžããã 耪è²é²æ¢å€ãšããŠã¯ãããšãã°ãç±³åœç¹èš±
2360290å·ãå2418613å·ãå2675314å·ãå
2701197å·ãå2704713å·ãå2728659å·ãå
2732300å·ãå2735765å·ãå2710801å·ãå
2816028å·ãè±åœç¹èš±1363921å·çã«èšèŒãããã
ã€ããããã³èªå°äœãç±³åœç¹èš±3457079å·ãå
3069262å·çã«èšèŒããã没é£åé žèªå°äœãç±³åœ
ç¹èš±2735765å·ãå3698909å·ãç¹å ¬æ49â20977
å·ãå52â6623å·ã«èšèŒãããïœâã¢ã«ã³ãã·ã
ãšããŒã«é¡ãç±³åœç¹èš±3432300å·ãå3573050å·ã
å3574627å·ãå3764337å·ãç¹éæ52â35633å·ã
å52â147434å·ãå52â152225å·ã«èšèŒãããïœ
âãªãã·ããšããŒã«èªå°äœãç±³åœç¹èš±3700455å·
ã«èšèŒã®ãã¹ããšããŒã«é¡çãããã 玫å€ç·åžåå€ãšããŠã¯ãäŸãã°ãã¢ãªãŒã«åºã§
眮æããããã³ãŸããªã¢ãŸãŒã«ååç©ïŒäŸãã°ã
ç±³åœç¹èš±3533794å·ã«èšèŒã®ãã®ïŒãïŒâãã¢ãŸãª
ãã³ååç©ïŒäŸãã°ãç±³åœç¹èš±3314794å·ãå
3352681å·ã«èšèŒã®ãã®ïŒããã³ãŸããšãã³ååç©
ïŒäŸãã°ãç¹éæ46â2784å·ã«èšèŒã®ãã®ïŒãã±ã€
ãé žãšã¹ãã«ååç©ïŒäŸãã°ãç±³åœç¹èš±3705805
å·ãå3707375å·ã«èšèŒã®ãã®ïŒããã¿ãžãšã³åå
ç©ïŒäŸãã°ãç±³åœç¹èš±4045229å·ã«èšèŒã®ãã®ïŒã
ãããã¯ããã³ãŸãªãã·ããŒã«ååç©ïŒäŸãã°ã
ç±³åœç¹èš±3700455å·ã«èšèŒã®ãã®ïŒãçšããããš
ãã§ãããããã«ãç±³åœç¹èš±3499762å·ãç¹éæ
54â48535å·ã«èšèŒã®ãã®ãçšããããšãã§ããã æ¬çºæã«äœ¿çšãããããã²ã³åéä¹³å€ã«çšãã
ããããã²ã³åéãšããŠã¯ãèåéãå¡©åéãæ²
èåéãå¡©èåéãå¡©æ²èåéçã®éåžžã®ããã²
ã³åéä¹³å€ã«äœ¿çšãããä»»æã®ãã®ãå«ãŸããã
æ¬çºæã«äœ¿çšãããããã²ã³åéã¯å¿ èŠãªæå æ³¢
é·åã«æå æ§ãä»äžããããã«ãé©åœãªå¢æè²çŽ
ã®éžæã«ããåå å¢æããªããããçšããããè²
çŽ ã«ã¯ã·ã¢ãã³è²çŽ ãã¡ãã·ã¢ãã³è²çŽ ãè€åã·
ã¢ãã³è²çŽ ãè€åã¡ãã·ã¢ãã³è²çŽ ãããããŒã©
ãŒã·ã¢ãã³è²çŽ ãããã·ã¢ãã³è²çŽ ãã¹ããªã«è²
çŽ åã³ãã·ãªããœããŒã«è²çŽ ãå å«ãããã æçšãªå¢æè²çŽ ãšããŠã¯ãäŸãã°ããã€ãç¹èš±
929080å·ãç±³åœç¹èš±2231658å·ãå2493748å·ãå
2503776å·ãå2519001å·ãå2912329å·ãå
3656959å·ãå3672897å·ãå3694217å·ãå
4025349å·ãå4046572å·ãè±åœç¹èš±1242588å·ã
ç¹å ¬æ44â14030å·ãå52â24844å·ã«èšèŒããã
ãã®ãæããããšãåºæ¥ãã ãããã®å¢æè²çŽ ã¯åç¬ã«çšããŠãããããã
ããã®çµåããçšããŠããããå¢æè²çŽ ã®çµåã
ã¯ç¹ã«ã匷è²å¢æã®ç®çã§ãã°ãã°çšããããã
ãã®ä»£è¡šäŸã¯ç±³åœç¹èš±2688545å·ãå2977229å·ã
å3397060å·ãå3522052å·ãå3527641å·ãå
3617293å·ãå3628964å·ãå3666480å·ãå
3672898å·ãå3679428å·ãå3703377å·ãå
3769301å·ãå3814609å·ãå3837862å·ãå
4026707å·ãè±åœç¹èš±1344281å·ãå1507803å·ã
ç¹å ¬æ43â4936å·ãå53â12375å·ãç¹éæ52â
110618å·ãå52â109925å·ã«èšèŒãããŠããã ãŸããæ¬çºæã«äœ¿çšãããããã²ã³åéä¹³å€
ã¯ãçš®ã ã®å ¬ç¥ã®åççšæ·»å å€ãå«æãããããš
ãåºæ¥ããäŸãã°Research Disclosave 17643ã«
èšèŒãããŠãããåŠãåççšæ·»å å€ã§ããã æ¬çºæããã²ã³åéåçæå ææã®æ¯æäœãšã
ãŠã¯ãã©ã¹ããã¯ãã€ã«ã ããã©ã¹ããã¯ã©ãã
ãŒãçŽããã©ã€ã¿çŽãåæçŽçãåŸæ¥ç¥ãããã
ã®ã䜿çšç®çã«å¿ããŠé©å®éžæããã°ããã ãŸããæ¬çºæã®ããã²ã³åéã«ã©ãŒåçæå æ
æã¯åœæ¥çã«æŒãŠçšããããä»»æã®æ§æãæ¡ãã
ãšãã§ããã ããããŠæ§æãããæ¬çºæã®ããã²ã³åéã«ã©
ãŒåçæå ææã¯ãé²å ããåŸçºè²çŸååŠçãšã
ãŠçš®ã ã®åçåŠçæ¹æ³ãçšããããã æ¬çºæã«ãããŠçºè²çŸå液ã«äœ¿çšãããè³éŠæ
第ïŒçŽã¢ãã³çºè²çŸåäž»è¬ã¯çš®ã ã®ã«ã©ãŒåçã
ãã»ã¹ã«ãããŠåºç¯å²ã«äœ¿çšãããŠããå ¬ç¥ã®ã
ã®ãå å«ãããããããã®çŸåå€ã¯ã¢ããããšã
ãŒã«ç³»ããã³ïœâããšãã¬ã³ãžã¢ãã³ç³»èªå°äœã
å«ãŸããããããã®ååç©ã¯éé¢ç¶æ ããå®å®ã®
ããäžè¬ã«å¡©ã®åœ¢ãäŸãã°å¡©é žå¡©ãŸãã¯ç¡«é žå¡©ã®
圢ã§äœ¿çšãããããŸããããã®ååç©ã¯ãäžè¬ã«
çºè²çŸå液ïŒã«ã€ããŠçŽ0.1ïœãçŽ30ïœã®æ¿åºŠã
奜ãŸããã¯çºè²çŸå液ïŒã«ã€ããŠçŽïŒïœãçŽ
1.5ïœã®æ¿åºŠã§äœ¿çšããã ã¢ããããšããŒã«ç³»çŸåå€ãšããŠã¯ãäŸãã°ïœ
âã¢ããããšããŒã«ãïœâã¢ããããšããŒã«ãïŒ
âã¢ããâïŒâãªãã·ãã«ãšã³ãïŒâã¢ããâïŒ
âãªãã·ãã«ãšã³ãïŒâãªãã·âïŒâã¢ããâ
ïŒïŒïŒâãžã¡ãã«ãã³ãŒã³ãªã©ãå«ãŸããã ç¹ã«æçšãªç¬¬ïŒçŽè³éŠæã¢ããç³»çºè²çŸåå€ã¯
ïŒNâ²âãžã¢ã«ãã«âïœâããšãã¬ã³ãžã¢ãã³
ç³»ååç©ã§ãããã¢ã«ãã«åºããã³ããšãã«åºã¯
ä»»æã®çœ®æåºã§çœ®æãããŠããŠãããããã®äžã§
ãç¹ã«æçšãªååç©äŸãšããŠã¯ïŒ®ïŒNâ²âãžãšã
ã«âïœâããšãã¬ã³ãžã¢ãã³å¡©é žå¡©ãâã¡ãã«
âïœâããšãã¬ã³ãžã¢ãã³å¡©é žå¡©ãïŒNâ²âãž
ã¡ãã«âïœâããšãã¬ã³ãžã¢ãã³å¡©é žå¡©ãïŒâã¢
ããâïŒâïŒïŒ®âãšãã«ââããã·ã«ã¢ããïŒâ
ãã«ãšã³ãâãšãã«ââβâã¡ã¿ã³ã¹ã«ãã³
ã¢ãããšãã«âïŒâã¡ãã«âïŒâã¢ããã¢ããªã³
ç¡«é žå¡©ãâãšãã«ââβâããããã·ãšãã«
ã¢ããã¢ããªã³ãïŒâã¢ããâïŒâã¡ãã«âïŒ
Nâ²âãžãšãã«ã¢ããªã³ãïŒâã¢ããââïŒïŒâ
ã¡ããã·ãšãã«ïŒââãšãã«âïŒâã¡ãã«ã¢ã
ãªã³âïœâãã«ãšã³ã¹ã«ãããŒããªã©ãæããã
ãšãã§ããã æ¬çºæã®åŠçã«ãããŠäœ¿çšãããçºè²çŸå液ã«
ã¯ãåèšç¬¬ïŒçŽè³éŠæã¢ãã³ç³»çºè²çŸåå€ã«å ã
ãŠæŽã«çºè²çŸå液ã«éåžžæ·»å ãããŠããçš®ã ã®æ
åãäŸãã°æ°Žé žåãããªãŠã ãçé žãããªãŠã ã
çé žã«ãªãŠã ãªã©ã®ã¢ã«ã«ãªå€ãã¢ã«ã«ãªéå±äº
ç¡«é žå¡©ãã¢ã«ã«ãªéå±éäºç¡«é žå¡©ãã¢ã«ã«ãªéå±
ããªã·ã¢ã³é žå¡©ãã¢ã«ã«ãªéå±ããã²ã³åç©ãã
ã³ãžã«ã¢ã«ã³ãŒã«ãæ°Žè»åå€ããã³æ¿ååå€ãªã©
ãä»»æã«å«æããããããšãã§ããããã®çºè²çŸ
å液ã®PHå€ã¯ãéåžžïŒä»¥äžã§ãããæãäžè¬çã«
ã¯çŽ10ãçŽ13ã§ããã æ¬çºæã«ãããŠã¯ãçºè²çŸååŠçããåŸãå®ç
èœãæããåŠç液ã§åŠçãããã該å®çèœãæã
ãåŠç液ã¯å®ç液ã§ããå Žåããã®åã«æŒçœåŠç
ãè¡ãããã該æŒçœå·¥çšã«çšããæŒçœæ¶²ãããã¯
æŒçœå®ç液ã«ãããŠäœ¿çšãããæŒçœå€ãšããŠã¯æ
æ©é žã®éå±é¯å¡©ãçšãããã該éå±é¯å¡©ã¯ãçŸå
ã«ãã€ãŠçæããéå±éãé žåããŠããã²ã³åé
ã«ããããšåæã«çºè²å€ã®æªçºè²éšãçºè²ããã
äœçšãæãããã®ã§ããã®æ§é ã¯ã¢ããããªã«ã«
ãã³é žãŸãã¯èé žãã¯ãšã³é žçã®ææ©é žã§éãã³
ãã«ããé çã®éå±ã€ãªã³ãé äœãããã®ã§ã
ãããã®ãããªææ©é žã®éå±é¯å¡©ã圢æãããã
ã«çšããããæã奜ãŸããææ©é žãšããŠã¯ãããª
ã«ã«ãã³é žãŸãã¯ã¢ããããªã«ã«ãã³é žãæãã
ããããããã®ããªã«ã«ãã³é žãŸãã¯ã¢ããããª
ã«ã«ãã³é žã¯ã¢ã«ã«ãªéå±å¡©ãã¢ã³ã¢ããŠã å¡©ã
ããã¯æ°Žæº¶æ§ã¢ãã³å¡©ã§ãã€ãŠãããã ãããã®å ·äœç代衚äŸãšããŠã¯æ¬¡ã®ãã®ãæã
ãããšãã§ããã ãïŒã ãšãã¬ã³ãžã¢ãã³ããã©é ¢é ž ãïŒã ãžãšãã¬ã³ããªã¢ãã³ãã³ã¿é ¢é ž ãïŒã ãšãã¬ã³ãžã¢ãã³ââïŒÎ²âãªãã·ãš
ãã«ïŒâïŒNâ²ïŒNâ²âããªé ¢é ž ãïŒã ãããã¬ã³ãžã¢ãã³ããã©é ¢é ž ãïŒã ãããªãããªé ¢é ž ãïŒã ãžã¯ããããµã³ãžã¢ãã³ããã©é ¢é ž ãïŒã ã€ãããžé ¢é ž ãïŒã ãžããããã·ãšãã«ã°ãªã·ã³ã¯ãšã³é ž
ïŒãŸãã¯é ç³é žïŒ
ãïŒã ãšãã«ãšãŒãã«ãžã¢ãã³ããã©é
¢é
ž
ã10ã ã°ãªã³ãŒã«ãšãŒãã«ãžã¢ãã³ããã©é
¢é
ž
ã11ã ãšãã¬ã³ãžã¢ãã³ããã©ããããªã³é
ž
ã12ã ããšãã¬ã³ãžã¢ãã³ããã©é
¢é
ž
ã13ã ãšãã¬ã³ãžã¢ãã³ããã©é
¢é
žãžãããªãŠ
ã å¡© ã14ã ãšãã¬ã³ãžã¢ãã³ããã©é ¢é žããã©ïŒã
ãªã¡ãã«ã¢ã³ã¢ããŠã ïŒå¡© ã15ã ãšãã¬ã³ãžã¢ãã³ããã©é ¢é žããã©ãã
ãªãŠã å¡© ã16ã ãžãšãã¬ã³ããªã¢ãã³ãã³ã¿é ¢é žãã³ã¿
ãããªãŠã å¡© ã17ã ãšãã¬ã³ãžã¢ãã³ââïŒÎ²âãªãã·ãš
ãã«ïŒâïŒNâ²ïŒNâ²âããªé ¢é žãããªãŠã å¡© ã18ã ãããã¬ã³ãžã¢ãã³ããã©é ¢é žãããªãŠ
ã å¡© ã19ã ãããªãããªé ¢é žãããªãŠã å¡© ã20ã ã·ã¯ããããµã³ãžã¢ãã³ããã©é ¢é žãã
ãªãŠã å¡© 䜿çšãããæŒçœæ¶²ã¯ãåèšã®åŠãææ©é žã®éå±
é¯å¡©ãæŒçœå€ãšããŠå«æãããšå ±ã«ãçš®ã ã®æ·»å
å€ãå«ãããšãã§ãããæ·»å å€ãšããŠã¯ããšãã«
ã¢ã«ã«ãªãã©ã€ããŸãã¯ã¢ã³ã¢ããŠã ãã©ã€ãã
äŸãã°èåã«ãªãŠã ãèåãããªãŠã ãå¡©åãã
ãªãŠã ãèåã¢ã³ã¢ããŠã çã®åããã²ã³åå€ã
éå±å¡©ããã¬ãŒãå€ãå«æãããããšãæãŸã
ãããŸãç¡Œé žå¡©ãèé žå¡©ãé ¢é žå¡©ãçé žå¡©ãçé ž
å¡©çã®PHç·©è¡å€ãã¢ã«ãã«ã¢ãã³é¡ãããªãšãã¬
ã³ãªããµã€ãé¡çã®éåžžæŒçœæ¶²ã«æ·»å ããããšã
ç¥ãããŠãããã®ãé©å®æ·»å ããããšãã§ããã æŽã«ãå®ç液åã³æŒçœå®ç液ã¯ãäºç¡«é žã¢ã³ã¢
ããŠã ãäºç¡«é žã«ãªãŠã ãéäºç¡«é žã¢ã³ã¢ããŠ
ã ãéäºç¡«é žã«ãªãŠã ãéäºç¡«é žãããªãŠã ãã¡
ã¿éäºç¡«é žã¢ã³ã¢ããŠã ãã¡ã¿éäºç¡«é žã«ãªãŠ
ã ãã¡ã¿éäºç¡«é žãããªãŠã çã®äºç¡«é žå¡©ãç¡Œ
é žãç¡Œç ãæ°Žé žåãããªãŠã ãæ°Žé žåã«ãªãŠã ã
çé žãããªãŠã ãçé žã«ãªãŠã ãéçé žãããªãŠ
ã ãéçé žã«ãªãŠã ãé ¢é žãé ¢é žãããªãŠã ãæ°Ž
é žåã¢ã³ã¢ããŠã çã®åçš®ã®å¡©ããæãPHç·©è¡å€
ãåç¬ãããã¯ïŒçš®ä»¥äžå«ãããšãã§ããã æŒçœå®ç液ïŒæµŽïŒã«æŒçœå®çè£å å€ãè£å ããª
ããæ¬çºæã®åŠçãè¡ãå Žåã該æŒçœå®ç液
ïŒæµŽïŒã«ããªç¡«é žå¡©ãããªã·ã¢ã³é žå¡©åã¯äºç¡«é ž
å¡©çãå«æããããŠããããã該æŒçœå®çè£å 液
ã«ãããã®å¡©é¡ãå«æããããŠåŠç济ã«è£å ããŠ
ãããã æ¬çºæã«ãããŠã¯æŒçœå®ç液ã®æŽ»æ§åºŠãé«ãã
çºã«æŒçœå®ç济äžåã³æŒçœå®çè£å 液ã®è²¯èµã¿ã³
ã¯å ã§ææã«ãã空æ°ã®å¹ã蟌ã¿ãåã¯é žçŽ ã®å¹
ã蟌ã¿ãè¡ã€ãŠãããããããã¯é©åœãªé žåå€ã
äŸãã°éé žåæ°ŽçŽ ãèçŽ é žå¡©ãéç¡«é žå¡©çãé©å®
æ·»å ããŠãããã ïŒå®æœäŸïŒ 次ã«æ¬çºæãå®æœäŸã«ãã€ãŠå ·äœçã«èª¬æã
ãã ãå®æœäŸ ïŒã 第ïŒè¡šã«ç€ºããããªæ¬çºæã®ããŒã³ã¿ã«ãã©ãŒ
ããã³æ¯èŒã®ã«ãã©ãŒãåã éïŒã¢ã«ã«å¯ŸããŠ
0.1ã¢ã«ãã€åããã«ãã©ãŒééã®ïŒåéã®ããª
ã¯ã¬ãžã«ãã¹ããšãŒãããã³ïŒåéã®é ¢é žãšãã«
ãå ã60âã«å æž©ããŠå®å šã«æº¶è§£ããããã®æº¶æ¶²
ãã¢ã«ã«ããŒã«ïŒ¢ïŒã¢ã«ãã«ããã¿ã¬ã³ã¹ã«ãã
ãŒããããŠãã³ç€Ÿè£œïŒã®ïŒïŒ 氎溶液120mlãå«ã
ïŒïŒ ãŒã©ãã³æ°Žæº¶æ¶²1200mlãšæ··åããè¶ é³æ³¢åæ£
æ©ã«ãŠä¹³ååæ£ãä¹³åç©ãåŸãããããã®ã¡ãã
ã®åæ£æ¶²ãç·ææ§æ²èåéä¹³å€ïŒæ²åéïŒã¢ã«ïŒ
å«æïŒïŒKgã«æ·»å ãã硬èå€ãšããŠïŒïŒïŒâãã¹
ïŒããã«ã¹ã«ããã«ïŒãšã¿ã³ã®ïŒïŒ 溶液ïŒæ°ŽïŒã¡
ã¿ããŒã«ïŒïŒïŒïŒïŒ120mlãå ããäžåŒãããã
éæãªããªãšã¹ãã«ããŒã¹äžã«å¡åžä¹Ÿç¥ããè©Šæ
ãäœæããïŒå¡åžéé20mgïŒ100cm2ïŒã ãã®ããã«ããŠåŸãããè©Šæãåžžæ³ã«åŸã€ãŠãŠ
ãšããžé²å ãè¡ã€ãåŸã以äžã®çŸååŠçãè¡ã€ã
çµæã第ïŒè¡šã«ç€ºãã
ã å¡© ã14ã ãšãã¬ã³ãžã¢ãã³ããã©é ¢é žããã©ïŒã
ãªã¡ãã«ã¢ã³ã¢ããŠã ïŒå¡© ã15ã ãšãã¬ã³ãžã¢ãã³ããã©é ¢é žããã©ãã
ãªãŠã å¡© ã16ã ãžãšãã¬ã³ããªã¢ãã³ãã³ã¿é ¢é žãã³ã¿
ãããªãŠã å¡© ã17ã ãšãã¬ã³ãžã¢ãã³ââïŒÎ²âãªãã·ãš
ãã«ïŒâïŒNâ²ïŒNâ²âããªé ¢é žãããªãŠã å¡© ã18ã ãããã¬ã³ãžã¢ãã³ããã©é ¢é žãããªãŠ
ã å¡© ã19ã ãããªãããªé ¢é žãããªãŠã å¡© ã20ã ã·ã¯ããããµã³ãžã¢ãã³ããã©é ¢é žãã
ãªãŠã å¡© 䜿çšãããæŒçœæ¶²ã¯ãåèšã®åŠãææ©é žã®éå±
é¯å¡©ãæŒçœå€ãšããŠå«æãããšå ±ã«ãçš®ã ã®æ·»å
å€ãå«ãããšãã§ãããæ·»å å€ãšããŠã¯ããšãã«
ã¢ã«ã«ãªãã©ã€ããŸãã¯ã¢ã³ã¢ããŠã ãã©ã€ãã
äŸãã°èåã«ãªãŠã ãèåãããªãŠã ãå¡©åãã
ãªãŠã ãèåã¢ã³ã¢ããŠã çã®åããã²ã³åå€ã
éå±å¡©ããã¬ãŒãå€ãå«æãããããšãæãŸã
ãããŸãç¡Œé žå¡©ãèé žå¡©ãé ¢é žå¡©ãçé žå¡©ãçé ž
å¡©çã®PHç·©è¡å€ãã¢ã«ãã«ã¢ãã³é¡ãããªãšãã¬
ã³ãªããµã€ãé¡çã®éåžžæŒçœæ¶²ã«æ·»å ããããšã
ç¥ãããŠãããã®ãé©å®æ·»å ããããšãã§ããã æŽã«ãå®ç液åã³æŒçœå®ç液ã¯ãäºç¡«é žã¢ã³ã¢
ããŠã ãäºç¡«é žã«ãªãŠã ãéäºç¡«é žã¢ã³ã¢ããŠ
ã ãéäºç¡«é žã«ãªãŠã ãéäºç¡«é žãããªãŠã ãã¡
ã¿éäºç¡«é žã¢ã³ã¢ããŠã ãã¡ã¿éäºç¡«é žã«ãªãŠ
ã ãã¡ã¿éäºç¡«é žãããªãŠã çã®äºç¡«é žå¡©ãç¡Œ
é žãç¡Œç ãæ°Žé žåãããªãŠã ãæ°Žé žåã«ãªãŠã ã
çé žãããªãŠã ãçé žã«ãªãŠã ãéçé žãããªãŠ
ã ãéçé žã«ãªãŠã ãé ¢é žãé ¢é žãããªãŠã ãæ°Ž
é žåã¢ã³ã¢ããŠã çã®åçš®ã®å¡©ããæãPHç·©è¡å€
ãåç¬ãããã¯ïŒçš®ä»¥äžå«ãããšãã§ããã æŒçœå®ç液ïŒæµŽïŒã«æŒçœå®çè£å å€ãè£å ããª
ããæ¬çºæã®åŠçãè¡ãå Žåã該æŒçœå®ç液
ïŒæµŽïŒã«ããªç¡«é žå¡©ãããªã·ã¢ã³é žå¡©åã¯äºç¡«é ž
å¡©çãå«æããããŠããããã該æŒçœå®çè£å 液
ã«ãããã®å¡©é¡ãå«æããããŠåŠç济ã«è£å ããŠ
ãããã æ¬çºæã«ãããŠã¯æŒçœå®ç液ã®æŽ»æ§åºŠãé«ãã
çºã«æŒçœå®ç济äžåã³æŒçœå®çè£å 液ã®è²¯èµã¿ã³
ã¯å ã§ææã«ãã空æ°ã®å¹ã蟌ã¿ãåã¯é žçŽ ã®å¹
ã蟌ã¿ãè¡ã€ãŠãããããããã¯é©åœãªé žåå€ã
äŸãã°éé žåæ°ŽçŽ ãèçŽ é žå¡©ãéç¡«é žå¡©çãé©å®
æ·»å ããŠãããã ïŒå®æœäŸïŒ 次ã«æ¬çºæãå®æœäŸã«ãã€ãŠå ·äœçã«èª¬æã
ãã ãå®æœäŸ ïŒã 第ïŒè¡šã«ç€ºããããªæ¬çºæã®ããŒã³ã¿ã«ãã©ãŒ
ããã³æ¯èŒã®ã«ãã©ãŒãåã éïŒã¢ã«ã«å¯ŸããŠ
0.1ã¢ã«ãã€åããã«ãã©ãŒééã®ïŒåéã®ããª
ã¯ã¬ãžã«ãã¹ããšãŒãããã³ïŒåéã®é ¢é žãšãã«
ãå ã60âã«å æž©ããŠå®å šã«æº¶è§£ããããã®æº¶æ¶²
ãã¢ã«ã«ããŒã«ïŒ¢ïŒã¢ã«ãã«ããã¿ã¬ã³ã¹ã«ãã
ãŒããããŠãã³ç€Ÿè£œïŒã®ïŒïŒ 氎溶液120mlãå«ã
ïŒïŒ ãŒã©ãã³æ°Žæº¶æ¶²1200mlãšæ··åããè¶ é³æ³¢åæ£
æ©ã«ãŠä¹³ååæ£ãä¹³åç©ãåŸãããããã®ã¡ãã
ã®åæ£æ¶²ãç·ææ§æ²èåéä¹³å€ïŒæ²åéïŒã¢ã«ïŒ
å«æïŒïŒKgã«æ·»å ãã硬èå€ãšããŠïŒïŒïŒâãã¹
ïŒããã«ã¹ã«ããã«ïŒãšã¿ã³ã®ïŒïŒ 溶液ïŒæ°ŽïŒã¡
ã¿ããŒã«ïŒïŒïŒïŒïŒ120mlãå ããäžåŒãããã
éæãªããªãšã¹ãã«ããŒã¹äžã«å¡åžä¹Ÿç¥ããè©Šæ
ãäœæããïŒå¡åžéé20mgïŒ100cm2ïŒã ãã®ããã«ããŠåŸãããè©Šæãåžžæ³ã«åŸã€ãŠãŠ
ãšããžé²å ãè¡ã€ãåŸã以äžã®çŸååŠçãè¡ã€ã
çµæã第ïŒè¡šã«ç€ºãã
ãè¡šã
ãè¡šã
ååŠçå·¥çšã«ãããŠã䜿çšããåŠç液çµæã¯äž
èšã®åŠãã§ããã æŒçœæ¶²çµæ ãšãã¬ã³ãžã¢ãã³ããã©é ¢é žéã¢ã³ã¢ããŠã å¡©
100ïœ ãšãã¬ã³ãžã¢ãã³ããã©é ¢é ž 10ïœ èåã¢ã³ã¢ããŠã 150ïœ æ°·é ¢é ž 40ml èçŽ é žãããªãŠã 10ïœ æ°Žãå ããŠïŒãšããã¢ã³ã¢ãã¢æ°ŽãŸãã¯æ°·é ¢
é žãçšããŠPH3.5ã«èª¿æŽããã å®ç液çµæ ããªç¡«é žã¢ã³ã¢ããŠã 180ïœ ç¡æ°Žäºç¡«é žãããªãŠã 12ïœ ã¡ã¿éäºç¡«é žãããªãŠã 2.5ïœ ãšãã¬ã³ãžã¢ãã³ããã©é ¢é žïŒãããªãŠã
0.5ïœ çé žãããªãŠã 10ïœ æ°Žãå ããŠïŒãšããã å®å®å液çµæ ãã«ããªã³ïŒ37ïŒ æ°Žæº¶æ¶²ïŒ ïŒml ã³ããã㯠氎ãå ããŠ
èšã®åŠãã§ããã æŒçœæ¶²çµæ ãšãã¬ã³ãžã¢ãã³ããã©é ¢é žéã¢ã³ã¢ããŠã å¡©
100ïœ ãšãã¬ã³ãžã¢ãã³ããã©é ¢é ž 10ïœ èåã¢ã³ã¢ããŠã 150ïœ æ°·é ¢é ž 40ml èçŽ é žãããªãŠã 10ïœ æ°Žãå ããŠïŒãšããã¢ã³ã¢ãã¢æ°ŽãŸãã¯æ°·é ¢
é žãçšããŠPH3.5ã«èª¿æŽããã å®ç液çµæ ããªç¡«é žã¢ã³ã¢ããŠã 180ïœ ç¡æ°Žäºç¡«é žãããªãŠã 12ïœ ã¡ã¿éäºç¡«é žãããªãŠã 2.5ïœ ãšãã¬ã³ãžã¢ãã³ããã©é ¢é žïŒãããªãŠã
0.5ïœ çé žãããªãŠã 10ïœ æ°Žãå ããŠïŒãšããã å®å®å液çµæ ãã«ããªã³ïŒ37ïŒ æ°Žæº¶æ¶²ïŒ ïŒml ã³ããã㯠氎ãå ããŠ
ãè¡šã
å®æœäŸâïŒã«æŒããè©Šæ11ã19ãåæ§ã«ãŠãšã
ãžé²å ãè¡ã€ãåŸã以äžã®çŸååŠçãè¡ã€ããçµ
æã¯ç¬¬ïŒè¡šã«ç€ºãã æ¯æ床ãèå æ§ã®æž¬å®ã¯å®æœäŸïŒãšåäžæ¹æ³ã§
è¡ã€ãã çŸååŠçå·¥çšïŒœ çºè²çŸå 38â ïŒå30ç§ æŒçœå®ç 33â ïŒå30ç§ å®å®ååŠçåã¯æ°ŽæŽåŠçïŒ 25ã30â ïŒå ä¹Ÿç¥ 75ã80â çŽïŒå ååŠçå·¥çšã«ãããŠã䜿çšããåŠç液çµæã¯äž
èšã®åŠãã§ããã
ãžé²å ãè¡ã€ãåŸã以äžã®çŸååŠçãè¡ã€ããçµ
æã¯ç¬¬ïŒè¡šã«ç€ºãã æ¯æ床ãèå æ§ã®æž¬å®ã¯å®æœäŸïŒãšåäžæ¹æ³ã§
è¡ã€ãã çŸååŠçå·¥çšïŒœ çºè²çŸå 38â ïŒå30ç§ æŒçœå®ç 33â ïŒå30ç§ å®å®ååŠçåã¯æ°ŽæŽåŠçïŒ 25ã30â ïŒå ä¹Ÿç¥ 75ã80â çŽïŒå ååŠçå·¥çšã«ãããŠã䜿çšããåŠç液çµæã¯äž
èšã®åŠãã§ããã
ãè¡šã
ããã
æŒçœå®ç液 ãšãã¬ã³ãžã¢ãã³ããã©é ¢é žç¬¬ïŒéã¢ã³ã¢ããŠ
ã ïŒæ°Žå¡© 60ïœ ãšãã¬ã³ãžã¢ãã³ããã©é ¢é ž ïŒïœ ããªç¡«é žã¢ã³ã¢ããŠã ïŒ70ïŒ æº¶æ¶²ïŒ 100ml äºç¡«é žã¢ã³ã¢ããŠã ïŒ40ïŒ æº¶æ¶²ïŒ 27.5ml çé žã«ãªãŠã ãŸãã¯æ°·é ¢é žã§PH7.1ã«èª¿æŽãæ°Ž
ãå ããŠå šéãïŒãšããã ïŒå®å®åæ¶²ïŒ ïŒâã¯ããâïŒâã¡ãã«âïŒâã€ãœãã¢ãŸãªã³
âïŒâãªã³ 1.0ïœ ãšãã¬ã³ã°ãªã³ãŒã« 10ïœ
æŒçœå®ç液 ãšãã¬ã³ãžã¢ãã³ããã©é ¢é žç¬¬ïŒéã¢ã³ã¢ããŠ
ã ïŒæ°Žå¡© 60ïœ ãšãã¬ã³ãžã¢ãã³ããã©é ¢é ž ïŒïœ ããªç¡«é žã¢ã³ã¢ããŠã ïŒ70ïŒ æº¶æ¶²ïŒ 100ml äºç¡«é žã¢ã³ã¢ããŠã ïŒ40ïŒ æº¶æ¶²ïŒ 27.5ml çé žã«ãªãŠã ãŸãã¯æ°·é ¢é žã§PH7.1ã«èª¿æŽãæ°Ž
ãå ããŠå šéãïŒãšããã ïŒå®å®åæ¶²ïŒ ïŒâã¯ããâïŒâã¡ãã«âïŒâã€ãœãã¢ãŸãªã³
âïŒâãªã³ 1.0ïœ ãšãã¬ã³ã°ãªã³ãŒã« 10ïœ
次ã®åå±€ãã¢ãã¿ãŒãŒåã®é
žåãã¿ã³ãå«æã
ãããªãšãã¬ã³æš¹èã³ãŒãçŽäžãªé çªã«å¡èšãã
ããšã«ããããã²ã³åéã«ã©ãŒåçæå ææã調
補ããã 以äžã®æ·»å éã¯100cm2åœãã®ãã®ã瀺ãã (1) 20mgã®ãŒã©ãã³ãééãšããŠïŒmgã®éææ§å¡©
èåéä¹³å€ããããŠïŒmgã®ïŒ¹âã«ãã©ãŒ*ãã
ã³0.1mgã®ïŒïŒïŒâãžâïœâãªã¯ãã«ãã€ãã
ããã³ã溶解ããïŒmgã®ãžâãªã¯ãã«ãã¿ã¬ãŒ
ãã«ãã©ãŒæº¶åªãå«ãå±€ã (2) 12mgã®ãŒã©ãã³ã0.5mgã®ïŒïŒïŒâãžâïœâ
ãªã¯ãã«ãã€ããããã³ããã³ïŒmgã®çŽ«å€ç·åž
åå€*ã溶解ããïŒmgã®ãžããã«ãã¿ã¬ãŒã玫
å€ç·åžåå€æº¶åªãå«ãäžéå±€ã (3) 18mgã®ãŒã©ãã³ãééãšããŠïŒmgã®ç·ææ§å¡©
èåéä¹³å€ããããŠïŒmgã®ïŒâã«ãã©ãŒ*ãšïŒ
mgã®é žåé²æ¢å€*ããã³0.2mgã®ïŒïŒïŒâãžâïœ
âãªã¯ãã«ãã€ããããã³ã溶解ãã2.5mgã®
ãžãªã¯ãã«ãã¿ã¬ãŒãã«ãã©ãŒæº¶åªãå«ãå±€ã (4) (2)ãšåãçµæç©ãå«ãäžéå±€ã (5) 16mgã®ãŒã©ãã³ãééãšããŠïŒmgã®èµ€ææ§å¡©
èåéä¹³å€ããããŠ3.5mgã®ïŒ£âã«ãã©ãŒ*ãã
ã³0.1mgã®ïŒïŒïŒâãžâïœâãªã¯ãã«ãã€ãã
ããã³ã溶解ãã2.0mgã®ããªã¯ã¬ãžã«ãã¹ã
ãšãŒãã«ãã©ãŒæº¶åªãå«ãå±€ã (6) ïŒmgã®ãŒã©ãã³ãå«æããŠãããŒã©ãã³ä¿è·
å±€ã (1)ãã(6)ã®åå±€ã«ã¯å¡åžå©å€ãæ·»å ããæŽã«(4)
ããã³(6)ã®å±€ã«ã¯ãŒã©ãã³æ¶æ©å€ãæ·»å ããã (2)ïŒ(4)ã®çŽ«å€ç·åžåå€ãšããŠã¯ãäžèšæ§é ã®
UVâïŒãšUVâïŒãæ··åããŠçšããã (3)ã®é žåé²æ¢å€ãšããŠããžâïœâãã³ãã«ãã€
ããããã³âãžâãªã¯ãã«ãšãŒãã«ãçšããã äžèšã®å€å±€æå ææã¯å®æœäŸâïŒãšåæ§ãªåŠç
ããããåå±€ã«çšããããâã«ãã©ãŒãïŒâã«
ãã©ãŒãâã«ãã©ãŒãšãã®çµæãè¡šïŒã«ç€ºãã åè©Šæã¯çœè²é²å ãããåŸã®ããŒã³ã¿æ¿åºŠã«ã€
ããŠæž¬å®ããã æ¯æ床ãèå æ§ã®æž¬å®ã¯å®æœäŸïŒãšåäžæ¹æ³ã§
è¡ã€ãã è¡šïŒããæ¬çºæã«ãã©ãŒã®è²çŽ ç»åã®èå æ§ã
ç§ããŠããããšã¯æãããã§ãããããŸã玫å€ç·
åžåå€ã䜿çšããããšã«ãã€ãŠæŽã«åäžããããš
ãæããã§ããã
ãããªãšãã¬ã³æš¹èã³ãŒãçŽäžãªé çªã«å¡èšãã
ããšã«ããããã²ã³åéã«ã©ãŒåçæå ææã調
補ããã 以äžã®æ·»å éã¯100cm2åœãã®ãã®ã瀺ãã (1) 20mgã®ãŒã©ãã³ãééãšããŠïŒmgã®éææ§å¡©
èåéä¹³å€ããããŠïŒmgã®ïŒ¹âã«ãã©ãŒ*ãã
ã³0.1mgã®ïŒïŒïŒâãžâïœâãªã¯ãã«ãã€ãã
ããã³ã溶解ããïŒmgã®ãžâãªã¯ãã«ãã¿ã¬ãŒ
ãã«ãã©ãŒæº¶åªãå«ãå±€ã (2) 12mgã®ãŒã©ãã³ã0.5mgã®ïŒïŒïŒâãžâïœâ
ãªã¯ãã«ãã€ããããã³ããã³ïŒmgã®çŽ«å€ç·åž
åå€*ã溶解ããïŒmgã®ãžããã«ãã¿ã¬ãŒã玫
å€ç·åžåå€æº¶åªãå«ãäžéå±€ã (3) 18mgã®ãŒã©ãã³ãééãšããŠïŒmgã®ç·ææ§å¡©
èåéä¹³å€ããããŠïŒmgã®ïŒâã«ãã©ãŒ*ãšïŒ
mgã®é žåé²æ¢å€*ããã³0.2mgã®ïŒïŒïŒâãžâïœ
âãªã¯ãã«ãã€ããããã³ã溶解ãã2.5mgã®
ãžãªã¯ãã«ãã¿ã¬ãŒãã«ãã©ãŒæº¶åªãå«ãå±€ã (4) (2)ãšåãçµæç©ãå«ãäžéå±€ã (5) 16mgã®ãŒã©ãã³ãééãšããŠïŒmgã®èµ€ææ§å¡©
èåéä¹³å€ããããŠ3.5mgã®ïŒ£âã«ãã©ãŒ*ãã
ã³0.1mgã®ïŒïŒïŒâãžâïœâãªã¯ãã«ãã€ãã
ããã³ã溶解ãã2.0mgã®ããªã¯ã¬ãžã«ãã¹ã
ãšãŒãã«ãã©ãŒæº¶åªãå«ãå±€ã (6) ïŒmgã®ãŒã©ãã³ãå«æããŠãããŒã©ãã³ä¿è·
å±€ã (1)ãã(6)ã®åå±€ã«ã¯å¡åžå©å€ãæ·»å ããæŽã«(4)
ããã³(6)ã®å±€ã«ã¯ãŒã©ãã³æ¶æ©å€ãæ·»å ããã (2)ïŒ(4)ã®çŽ«å€ç·åžåå€ãšããŠã¯ãäžèšæ§é ã®
UVâïŒãšUVâïŒãæ··åããŠçšããã (3)ã®é žåé²æ¢å€ãšããŠããžâïœâãã³ãã«ãã€
ããããã³âãžâãªã¯ãã«ãšãŒãã«ãçšããã äžèšã®å€å±€æå ææã¯å®æœäŸâïŒãšåæ§ãªåŠç
ããããåå±€ã«çšããããâã«ãã©ãŒãïŒâã«
ãã©ãŒãâã«ãã©ãŒãšãã®çµæãè¡šïŒã«ç€ºãã åè©Šæã¯çœè²é²å ãããåŸã®ããŒã³ã¿æ¿åºŠã«ã€
ããŠæž¬å®ããã æ¯æ床ãèå æ§ã®æž¬å®ã¯å®æœäŸïŒãšåäžæ¹æ³ã§
è¡ã€ãã è¡šïŒããæ¬çºæã«ãã©ãŒã®è²çŽ ç»åã®èå æ§ã
ç§ããŠããããšã¯æãããã§ãããããŸã玫å€ç·
åžåå€ã䜿çšããããšã«ãã€ãŠæŽã«åäžããããš
ãæããã§ããã
Claims (1)
- ãç¹èš±è«æ±ã®ç¯å²ã ïŒ æ¯æäœäžã«å°ããšãäžå±€ã®ããã²ã³åéä¹³å€
å±€ãæããããã²ã³åéã«ã©ãŒåçæå ææã«ã
ããŠãåèšããã²ã³åéä¹³å€å±€äžã«äžèšäžè¬åŒã§
瀺ãããããŒã³ã¿ã«ãã©ãŒã®å°ããšãäžã€ãå«æ
ãããŠããããšãç¹åŸŽãšããããã²ã³åéã«ã©ãŒ
åçæå ææã ãåŒäžãR1ã¯ïŒçŽã¢ã«ãã«åºãR2ã¯ïŒçŽãŸã
ã¯ïŒçŽã¢ã«ãã«åºãè¡šãããã¯çºè²çŸåäž»è¬ã®
é žåäœãšåå¿ããŠé¢è±ããæ°ŽçŽ åå以å€ã®é¢è±åº
ãè¡šãããã
Priority Applications (10)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP24300984A JPS61120149A (ja) | 1984-11-15 | 1984-11-15 | ããã²ã³åéã«ã©âåçæå ææ |
| US06/775,684 US4665015A (en) | 1984-09-14 | 1985-09-13 | Silver halide color photographic material containing a magenta coupler |
| AU47440/85A AU4744085A (en) | 1984-09-14 | 1985-09-13 | Pyrazolo-triazole magenta couplers and their use in silver halide colour photography |
| EP19850306568 EP0178788B1 (en) | 1984-09-14 | 1985-09-16 | Silver halide color photographic material |
| CA000490830A CA1266394A (en) | 1984-11-15 | 1985-09-16 | Silver halide color photographic material |
| DE8585306568T DE3575796D1 (de) | 1984-09-14 | 1985-09-16 | Farbphotographisches silberhalogenidmaterial. |
| AU49948/85A AU4994885A (en) | 1984-09-14 | 1985-11-15 | Silver halide colour photographic material |
| AU37011/89A AU3701189A (en) | 1984-09-14 | 1989-06-23 | Silver halide color photographic material |
| AU37006/89A AU3700689A (en) | 1984-09-14 | 1989-06-23 | Silver halide color photographic material |
| AU37010/89A AU3701089A (en) | 1984-09-14 | 1989-06-23 | Silver halide color photo-sensitive material |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP24300984A JPS61120149A (ja) | 1984-11-15 | 1984-11-15 | ããã²ã³åéã«ã©âåçæå ææ |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS61120149A JPS61120149A (ja) | 1986-06-07 |
| JPH0554935B2 true JPH0554935B2 (ja) | 1993-08-13 |
Family
ID=17097529
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP24300984A Granted JPS61120149A (ja) | 1984-09-14 | 1984-11-15 | ããã²ã³åéã«ã©âåçæå ææ |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS61120149A (ja) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0616160B2 (ja) * | 1985-10-18 | 1994-03-02 | å¯å£«åçãã€ã«ã æ ªåŒäŒç€Ÿ | ããã²ã³åéã«ã©âåçæå ææ |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6165245A (ja) * | 1984-09-06 | 1986-04-03 | Fuji Photo Film Co Ltd | ããã²ã³åéã«ã©âåçæå ææ |
| JPH0260167A (ja) * | 1988-08-26 | 1990-02-28 | Seiko Epson Corp | åå°äœè£ 眮 |
-
1984
- 1984-11-15 JP JP24300984A patent/JPS61120149A/ja active Granted
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6165245A (ja) * | 1984-09-06 | 1986-04-03 | Fuji Photo Film Co Ltd | ããã²ã³åéã«ã©âåçæå ææ |
| JPH0260167A (ja) * | 1988-08-26 | 1990-02-28 | Seiko Epson Corp | åå°äœè£ 眮 |
Also Published As
| Publication number | Publication date |
|---|---|
| JPS61120149A (ja) | 1986-06-07 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US4665015A (en) | Silver halide color photographic material containing a magenta coupler | |
| US4607002A (en) | Silver halide color photo-sensitive material | |
| JP2717481B2 (ja) | ããã²ã³åéã«ã©ãŒåçæå ææ | |
| US4840886A (en) | Silver halide color photographic material containing a 1h-pyrazole (3,2-C)-s-triazole derived magenta coupler | |
| JPH0643611A (ja) | åççšã«ãã©ãŒåã³ããã²ã³åéã«ã©ãŒåçæå ææ | |
| JPH0417411B2 (ja) | ||
| US4675280A (en) | Silver halide color photographic material containing a 1H-pyrazolo [3,2-C]-S | |
| JPH0562729B2 (ja) | ||
| EP0183445B1 (en) | Silver halide color photo-sensitive material | |
| JPH04190348A (ja) | ããã²ã³åéã«ã©ãŒåçæå ææ | |
| JPH043860B2 (ja) | ||
| JPH04172447A (ja) | ã·ã¢ã³ã«ãã©ãŒãã·ã¢ã³ç»å圢ææ¹æ³åã³ããã²ã³åéã«ã©ãŒåçæå ææ | |
| JPH04188139A (ja) | æ°èŠãªè²çŽ 圢æã«ãã©ãŒããããçšããã«ã©ãŒç»å圢ææ¹æ³åã³ããã²ã³åéã«ã©ãŒåçæå ææ | |
| JPH03174153A (ja) | ã«ã©ãŒç»å圢ææ¹æ³ | |
| JPH0573010B2 (ja) | ||
| JPH0380296B2 (ja) | ||
| JPH0554935B2 (ja) | ||
| JPH04190347A (ja) | æ°èŠãªè²çŽ 圢æã«ãã©ãŒããã³è©²ã«ãã©ãŒãå«æããããã²ã³åéã«ã©ãŒåçæå ææ | |
| JPS61120150A (ja) | ããã²ã³åéã«ã©âåçæå ææ | |
| JPS61120148A (ja) | ããã²ã³åéã«ã©âåçæå ææ | |
| JP2618533B2 (ja) | ããã²ã³åéã«ã©ãŒåçæå ææåã³ããã²ã³åéã«ã©ãŒç»å圢ææ¹æ³ | |
| JPH07140615A (ja) | ããã²ã³åéã«ã©ãŒæå ææ | |
| JPH0566574B2 (ja) | ||
| JPH0677142B2 (ja) | ããã²ã³åéã«ã©ãŒåçæå ææ | |
| JPH09292682A (ja) | ããã²ã³åéã«ã©ãŒåçæå ææ |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| S531 | Written request for registration of change of domicile |
Free format text: JAPANESE INTERMEDIATE CODE: R313531 |
|
| S533 | Written request for registration of change of name |
Free format text: JAPANESE INTERMEDIATE CODE: R313533 |
|
| R350 | Written notification of registration of transfer |
Free format text: JAPANESE INTERMEDIATE CODE: R350 |
|
| EXPY | Cancellation because of completion of term |