JPH0532395B2 - - Google Patents

Info

Publication number
JPH0532395B2
JPH0532395B2 JP58039338A JP3933883A JPH0532395B2 JP H0532395 B2 JPH0532395 B2 JP H0532395B2 JP 58039338 A JP58039338 A JP 58039338A JP 3933883 A JP3933883 A JP 3933883A JP H0532395 B2 JPH0532395 B2 JP H0532395B2
Authority
JP
Japan
Prior art keywords
theophylline
oxadiazol
methyl
ethane
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP58039338A
Other languages
English (en)
Japanese (ja)
Other versions
JPS5910586A (ja
Inventor
Korubonitsutsu Dejee
Somoru Maaria
Heeya Jerujerii
Suboda Ida
Kisu Paaru
Gentsui Chaba
Paaroshu Endore
Koaachu Gaaboru
Kun Yuudeito
Minkeru Emiru
Sebesucheen Juura
Suuchu Tamaashu
Uiraagu Shaandoru
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chinoin Private Co Ltd
Original Assignee
Chinoin Gyogyszer es Vegyeszeti Termekek Gyara Zrt
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chinoin Gyogyszer es Vegyeszeti Termekek Gyara Zrt filed Critical Chinoin Gyogyszer es Vegyeszeti Termekek Gyara Zrt
Publication of JPS5910586A publication Critical patent/JPS5910586A/ja
Publication of JPH0532395B2 publication Critical patent/JPH0532395B2/ja
Granted legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D473/00Heterocyclic compounds containing purine ring systems
    • C07D473/02Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/04Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
    • C07D473/06Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
    • C07D473/08Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3 with methyl radicals in positions 1 and 3, e.g. theophylline
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/08Bronchodilators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/14Antitussive agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
JP58039338A 1982-03-12 1983-03-11 オキサジアゾリルアルキルテオフイリン,その製法及びそれを含む薬剤組成物 Granted JPS5910586A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
HU762/82 1982-03-12
HU82762A HU190377B (en) 1982-03-12 1982-03-12 Process for preparing theophyllinyl-alkyl-oxadiazoles

Publications (2)

Publication Number Publication Date
JPS5910586A JPS5910586A (ja) 1984-01-20
JPH0532395B2 true JPH0532395B2 (en, 2012) 1993-05-14

Family

ID=10951220

Family Applications (1)

Application Number Title Priority Date Filing Date
JP58039338A Granted JPS5910586A (ja) 1982-03-12 1983-03-11 オキサジアゾリルアルキルテオフイリン,その製法及びそれを含む薬剤組成物

Country Status (17)

Country Link
US (1) US4565817A (en, 2012)
EP (1) EP0089028B1 (en, 2012)
JP (1) JPS5910586A (en, 2012)
AT (1) ATE34575T1 (en, 2012)
BG (1) BG60434B2 (en, 2012)
DD (1) DD207377A5 (en, 2012)
DE (1) DE3376749D1 (en, 2012)
DK (1) DK161385C (en, 2012)
ES (2) ES520860A0 (en, 2012)
FI (1) FI72320C (en, 2012)
GR (1) GR78450B (en, 2012)
HU (1) HU190377B (en, 2012)
IL (1) IL68093A0 (en, 2012)
NO (1) NO159794C (en, 2012)
PL (2) PL138857B1 (en, 2012)
SK (1) SK170183A3 (en, 2012)
SU (3) SU1322981A3 (en, 2012)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU190377B (en) * 1982-03-12 1986-08-28 Chinoin Gyogyszer Es Vegyeszet Process for preparing theophyllinyl-alkyl-oxadiazoles
LV5262A3 (lv) * 1986-10-09 1993-10-10 Chinoin Gyogyszer Es Vegyeszet Oksadiazolilalkilpurina atvasinajumi kam piemit pretklepus aktivitate
HU197574B (en) * 1986-10-09 1989-04-28 Chinoin Gyogyszer Es Vegyeszet Process for production of derivatives of 3,7-dihydro-3-methil-7-//1,2,4-oxadiasole/-3-il/alkylenil/-1h-purin-2,6-dion and medical compositions containing these substances
HU198933B (en) * 1987-11-02 1989-12-28 Chinoin Gyogyszer Es Vegyeszet Process for producing new xanthine derivatives and pharmaceutical compositions comprising same as active ingredient
HU206884B (en) * 1990-11-22 1993-01-28 Chinoin Gyogyszer Es Vegyeszet Process for producing purin derivatives and pharmaceutical compositions containing them
US5817662A (en) * 1992-11-09 1998-10-06 Cell Therapeutics, Inc. Substituted amino alkyl compounds
US5340813A (en) * 1992-11-09 1994-08-23 Cell Therapeutics, Inc. Substituted aminoalkyl xanthine compounds
AU6087894A (en) * 1993-01-14 1994-08-15 Cell Therapeutics, Inc. Acetal or ketal substituted therapeutic compounds
US6103730A (en) * 1994-03-24 2000-08-15 Cell Therapeutics, Inc. Amine substituted compounds
US5807861A (en) * 1994-03-24 1998-09-15 Cell Therapeutics, Inc. Amine substituted xanthinyl compounds
US5801182A (en) * 1994-03-24 1998-09-01 Cell Therapeutics, Inc. Amine substituted compounds
US20070215201A1 (en) * 2006-03-17 2007-09-20 Lawrence Curtin Photovoltaic cell with integral light transmitting waveguide in a ceramic sleeve
JP2010530901A (ja) * 2007-06-22 2010-09-16 ハイドラ バイオサイエンシズ インコーポレイテッド 障害を治療するための方法および組成物
WO2009140517A1 (en) 2008-05-14 2009-11-19 Hydra Biosciences, Inc. Compounds and compositions for treating chemical warfare agent-induced injuries

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1063323B (de) * 1957-06-29 1959-08-13 Willi Keil Zentrifugalgeblaese oder -pumpe
NL132134C (en, 2012) * 1963-03-22
DE1620576A1 (de) * 1966-11-25 1970-02-26 Troponwerke Dinklage & Co Verfahren zur Herstellung von Theophyllin- und Theobrominverbindungen
DE1670497C3 (de) * 1967-06-06 1973-12-20 Chinoin Gyogyszer- Es Vegyeszeti Termekek Gyara Rt, Budapest Isochinohnderivate und Verfahren zu deren Herstellung
IT1156913B (it) * 1978-03-13 1987-02-04 Geymonat Sud Spa Composto ad attivita farmaceutica e procedimento per la sua preparazione
EP0011399A1 (en) * 1978-11-11 1980-05-28 FISONS plc N-substituted theophyllines, processes for their preparation and pharmaceutical compositions containing them
IT1195267B (it) * 1980-04-15 1988-10-12 Abc Ist Biolog Chem Spa Derivati teofillinmetildiossolanici,procedimento per la loro preparazione e relative composizioni farmaceutiche
HU190377B (en) * 1982-03-12 1986-08-28 Chinoin Gyogyszer Es Vegyeszet Process for preparing theophyllinyl-alkyl-oxadiazoles

Also Published As

Publication number Publication date
DE3376749T2 (en, 2012) 1988-06-30
EP0089028A1 (de) 1983-09-21
SK278001B6 (sk) 1995-09-13
ES8504195A1 (es) 1985-04-16
PL138550B1 (en) 1986-10-31
SK170183A3 (en) 1995-09-13
PL138857B1 (en) 1986-11-29
NO159794C (no) 1989-02-08
FI72320B (fi) 1987-01-30
DK118083D0 (da) 1983-03-11
US4565817A (en) 1986-01-21
DK161385B (da) 1991-07-01
FI72320C (fi) 1987-05-11
PL240990A1 (en) 1985-01-02
PL249225A1 (en) 1985-06-04
DD207377A5 (de) 1984-02-29
IL68093A0 (en) 1983-06-15
SU1297729A3 (ru) 1987-03-15
ES534146A0 (es) 1985-07-01
NO830843L (no) 1983-09-13
SU1322981A3 (ru) 1987-07-07
SU1344756A1 (ru) 1987-10-15
DK161385C (da) 1991-12-16
FI830831L (fi) 1983-09-13
ATE34575T1 (de) 1988-06-15
JPS5910586A (ja) 1984-01-20
GR78450B (en, 2012) 1984-09-27
ES520860A0 (es) 1985-04-16
DE3376749D1 (en) 1988-06-30
EP0089028B1 (de) 1988-05-25
ES8505999A1 (es) 1985-07-01
DK118083A (da) 1983-09-13
BG60434B2 (bg) 1995-03-31
HU190377B (en) 1986-08-28
NO159794B (no) 1988-10-31
FI830831A0 (fi) 1983-03-11

Similar Documents

Publication Publication Date Title
JPH0532395B2 (en, 2012)
JPH0242079A (ja) 縮合ピリミジン誘導体およびその製造方法
US4840949A (en) Oxadiazole-alkyl-purine derivatives useful as antitussive agents
SG181958A1 (en) Process for making a metabotropic glutamate receptor positive allosteric modulator - 874
JPH06192242A (ja) キナゾリン化合物の製造に有用なオキサジアゾール誘導体
HU207053B (en) Process for producing cinnolinecarboxamide derivatives and pharmaceuitcal compositions comprising such compounds
US3316266A (en) 3-aminopyrazinoic acid derivatives and process for their preparation
JPS6045878B2 (ja) N,n’−二置換環状ジアミン及び精神病治療用薬剤
EP0402232A1 (fr) Dérivés de pyridobenzoindole, leur préparation et les compositions qui les contiennent
US3478028A (en) 4-substituted-1-hydroxylaminophthalazines
US4260612A (en) Antiallergic nitrogen bridge-head compounds
JPS61180786A (ja) 新規なイミダゾ〔1,2−a〕ピリミジン類及びそれらの塩、それら化合物及びそれらの中間体の製造方法並びにそれらの製薬組成物への使用
JPS584025B2 (ja) 4;− アルキルジオキシアルキレン −5− ベンジルピリミジン ノ セイホウ
JPH07157482A (ja) 新規なインドール類またはその塩
CA2073064A1 (en) (hetero) 4-arylmethoxy phenyl diazole derivatives, method for preparing same and their therapeutical applications
DK171117B1 (da) Ergolinderivater, fremgangsmåde til fremstilling deraf, forbindelser til anvendelse som mellemprodukter ved fremgangsmåden samt farmaceutiske præparater indeholdende ergolinderivaterne
FI71313C (fi) Analogifoerfarande foer framstaellning av terapeutiskt anvaendbar 2-(1-fenylbensimidazolyl)acetohydroxamsyra
JPH05262770A (ja) 化学的製法
JPH0674260B2 (ja) キノリン誘導体、そのエステルおよびその塩
JP2966893B2 (ja) 新規キノロン―3―カルバルデヒド誘導体およびその塩
JPS6228148B2 (en, 2012)
CZ282155B6 (cs) Nové theofylinové deriváty, substituované v poloze -7 a způsob jejich výroby i použití
JPS6253972A (ja) ピリダジン誘導体及びその製法
EP0449346A2 (en) 4-Piperidinyl-ergoline derivatives
SI8711857A (sl) Derivati oksadiazol-alkil-purina