JPH04215768A - 膨張式ステント - Google Patents

膨張式ステント

Info

Publication number
JPH04215768A
JPH04215768A JP3016116A JP1611691A JPH04215768A JP H04215768 A JPH04215768 A JP H04215768A JP 3016116 A JP3016116 A JP 3016116A JP 1611691 A JP1611691 A JP 1611691A JP H04215768 A JPH04215768 A JP H04215768A
Authority
JP
Japan
Prior art keywords
stent
hollow
wall
hydrophilic material
hollow wall
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP3016116A
Other languages
English (en)
Other versions
JPH0773607B2 (ja
Inventor
Thomas A Silvestrini
トーマス・エイ・シルヴェストリーニ
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
MTG Divestitures LLC
Original Assignee
Pfizer Hospital Products Group Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Hospital Products Group Inc filed Critical Pfizer Hospital Products Group Inc
Publication of JPH04215768A publication Critical patent/JPH04215768A/ja
Publication of JPH0773607B2 publication Critical patent/JPH0773607B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
    • A61F2/88—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure the wire-like elements formed as helical or spiral coils
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
    • A61F2/90—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
    • A61F2/90—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
    • A61F2/91—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2002/825—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents having longitudinal struts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2250/0003—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof having an inflatable pocket filled with fluid, e.g. liquid or gas
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2250/0058—Additional features; Implant or prostheses properties not otherwise provided for
    • A61F2250/0067—Means for introducing or releasing pharmaceutical products into the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/10—Balloon catheters
    • A61M25/1002—Balloon catheters characterised by balloon shape

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Cardiology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Veterinary Medicine (AREA)
  • Vascular Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Optics & Photonics (AREA)
  • Physics & Mathematics (AREA)
  • Materials For Medical Uses (AREA)
  • Prostheses (AREA)
  • Media Introduction/Drainage Providing Device (AREA)

Abstract

(57)【要約】本公報は電子出願前の出願データであるた
め要約のデータは記録されません。

Description

【発明の詳細な説明】
【０００１】
【産業上の利用分野】本発明は一般に、体腔、たとえば
管（ｄｕｃｔ，ｖｅｓｓｅｌ）を開いた状態に維持する
ために用いられるステント、特に中空の膨張式壁を備え
たステントに関するものである。
【０００２】
【従来の技術】処置を行わない場合には閉じているかま
たは閉塞している体腔、たとえば管を開いた形状に維持
するためにステントを用いることは十分に認められた処
置法である。現在一般に用いられているステントには、
たとえば米国特許第４，６５５，７７１号明細書に記載
される自己膨張式ステント、およびステント内で膨張さ
せるバルーンによりその体腔部位で膨張するステントが
含まれる。いずれの場合もステントは通常は金属製であ
り、従って一般にある程度の剛性および最小の可撓性を
もつ。
【０００３】
【発明が解決しようとする課題】従って本発明の第１の
目的は、挿入に際しては軟質かつ柔軟であり、ただし処
置部位に配置されたのちは適切な程度の剛性および硬質
性を備えうるステントを提供することである。本発明の
他の目的は、少なくとも壁構造の一部が半透膜から製造
された中空の膨張式壁であるステントを提供することで
ある。本発明のさらに他の目的は、中空壁の内部に、液
体を吸収することにより体積が増大して結果的に壁を膨
張させうる親水性材料が配置されたステントを提供する
ことである。本発明のさらに他の目的は、親水性材料と
共に薬物が配置されたステントを提供することである。 これらおよび他の本発明の目的は以下の記載により明ら
かになるであろう。
【０００４】
【課題を解決するための手段】本発明は、少なくともそ
の一部が中空壁である壁構造を含む、体腔内に配置する
ためのステントである。中空壁の内部には、中空壁内へ
液体が導入された際に膨潤し、これにより中空壁を膨張
させる親水性材料が配置され、たとえばこれはゲル状で
あってもよい。内部に親水性材料が配置された中空壁は
半透膜から製造され、これにより配置部位にあるステン
トの周囲組織からの体液は膜を貫通して親水性材料を膨
潤させ、これにより壁を膨張させる。親水性材料と共に
、ステント配置部位において膜を通して放出させるため
の治療薬が配置されてもよい。本発明のステントを用い
うる体腔の例には、動脈、静脈、尿道および尿管、胆管
、肝管および膵管、気管、食道および腸部分、精管およ
び卵管、耳管ならびに涙管が含まれるが、必ずしもこれ
らに限定されない。ステントの壁構造全体が中空壁であ
ってもよく、壁構造に中空部分および非中空部分の両方
、たとえば互いに編組、製織、または巻織されることに
より互いに保持された中空繊維および中実繊維が含まれ
てもよい。
【０００５】本発明は、配置したのち膨張させた時点で
は体腔を支持するステントを提供するが、ステントは膨
張していない状態でその部位へ送入することができるの
で、結果的に送入時には小型であるのものを提供し、体
腔内での配置性が向上する。
【０００６】現時点で好ましい本発明の形態を図面に示
す。
【０００７】図１には体腔内に配置するためのチューブ
状ステント１０が示される。ステント１０の壁構造全体
が、中空の膨張式壁１２であり、これはステント１０が
体腔内に配置された際に組織の内生を容易にするために
多数の半径方向開口１６が貫通したバルーン１８からな
る。壁１２は、たとえば当技術分野で既知の半透膜を形
成しうる、かつ適切な膨張圧に耐えうるポリマーから構
成される半透膜から製造される。その例にはポリアミド
、ポリエステル、ポリウレタン、およびエチレンビニル
アルコールが含まれるが、これらに限定されない。ステ
ント１０の中空壁１２の内部には親水性材料３２が配置
される。これは浸透圧希釈により液体を吸収または吸引
しうるものであり、これにより材料３２が与える体積ま
たは圧力が増大する。この親水性材料は浸透圧を生じる
生体適合性物質のいずれであってもよい。その例には無
機塩類、有機塩類、糖類、多糖類、高分子ヒドロゲルま
たは両性分子が含まれるが、これらに限定されない。 好ましい材料の１つはヒドロゲル、たとえばポリビニル
アルコールである。
【０００８】使用に際しては、ステント１０をまず膨張
していない状態で、通常の適宜な送入手段、たとえば適
宜なサイズのカテーテル（図示されていない）により、
目的部位に配置する。適量の周囲組織液が壁１２内へ拡
散し、これにより親水性材料３２が膨潤してステント１
０を膨張させ、従ってこれが体腔内壁に突き当たること
により適所に自立滞在しうるのに十分な期間、目的位置
におけるこの配置が送入手段によって維持される。もち
ろん壁１２の製造に用いられる半透膜は、膨張した親水
性材料により内部に形成される圧力による破裂に耐える
のに十分な強度のものでなければならない。最終的に半
径方向開口１６を通して組織の内生が起こる。
【０００９】ステント１０は徐放性ドラッグデリバリー
用具としても使用しうる。特に薬物を親水性材料３２と
共に、別個の成分として、またはそれとブレンドして配
置しうる。こうして薬物は半透膜を通して周囲組織内へ
長期間にわたって放出されるであろう。もちろんこうし
て含有される薬物は適宜な濃度で供給され、目的とする
放出速度を達成するために必要に応じキャリヤーを含ん
でもよい。さらに薬物の分子量は親水性材料のものより
低くすべきである。この種の薬物の一例はピロキシカム
−−フェルデン（Ｆｅｌｄｅｎｅ）として市販される；
ファイザー製、ニューヨーク州ニューヨーク−−であり
、ステント当たり約２０−５００ｍｇの量で存在する。 薬物は治療効果を得るためにステント１０からそののち
徐々に放出されるべく、別個の成分であってもよく、ま
たは親水性材料３２と混合するかもしくはそれに溶解す
ることにより親水性材料に内包されてもよい。もちろん
異なるステント用途につき異なる薬物を用いることがで
きる。この種の薬物の例には心臓血管用の抗トロンビン
薬、尿路処置用の石灰沈着防止薬、およびステント処置
またはバルーン血管形成術に対する生物反応を抑制する
ための抗炎症薬または増殖抑制薬が含まれるが、これら
に限定されない。
【００１０】ステント１０は、２枚の同心チューブ状膜
を用いて構成され、これにより外側膜の内面と内側膜の
外面が中空構造体の内面を定めるものであってもよい。 ２枚の膜の間にゲルを導入したのち当技術分野で既知の
膜シール法によりステント１０の末端をシールし、同時
に半径方向開口１６を切り取り、シールする。
【００１１】図２は体腔内に配置するためのチューブ状
ステント２０の第２形態を示す。ステント２０の壁構造
全体が編組された多数の中空繊維２６からなる中空の膨
張式壁２４である。実質的に壁構造全体が図２に示すよ
うに編組された多数の中空繊維２６からなっていてもよ
いが、図３に示すチューブ状ステント４０のように壁４
４の一部のみが中空繊維２６からなる構造であってもよ
い。この場合ステント４０の中空繊維２６は中実繊維２
８と編組されている。ステント２０、４０が体腔内の適
所に配置された際に組織の内生を容易にすべく、多数の
半径方向開口２９ががそれぞれの壁２４、４４を貫通し
て伸びる。図１に示すステント１０のバルーン１８と同
様にステント２０、４０の中空繊維２６は、たとえば当
技術分野で既知の半透膜を形成しうるポリマーから構成
される半透膜から製造される。その例にはポリアミド、
ポリエステル、ポリウレタン、およびエチレンビニルア
ルコールが含まれるが、これらに限定されない。先に図
１に関して述べたように、中空繊維２６の内部には親水
性材料が配置される。これは液体を吸収しうるものであ
り、これによりこの材料の体積が増大し、繊維２６を膨
張させる。同様に先に述べたように、親水性材料は繊維
２６の半透膜を通して周囲組織内へ長期間にわたって放
出される薬物を内包しうる。
【００１２】ステント２０、４０は先に図１に関して述
べたように、体腔内の目的部位に配置される。同様に、
適量の周囲組織液が繊維２６内へ拡散し、これにより親
水性材料が膨潤してステント２０、４０を膨張させ、従
ってこれが体腔内壁に突き当たることにより適所に自立
滞在しうるのに十分な期間、目的位置におけるこの配置
が送入手段によって維持される。もちろん中空繊維２６
の製造に用いられる半透膜は、膨張した親水性材料によ
り内部に形成される圧力による破裂に耐えるのに十分な
強度のものでなければならない。半径方向開口２９を通
して組織の内生が起こる。
【００１３】ここに記載するステント２０を構成する１
方法は、当技術分野で既知の溶剤キャスチング法の採用
である。たとえばポリマー溶液がダイの一部から送り出
されて中空壁を形成する適宜な形状のダイを設置する。 同時に親水性材料、たとえばゲルをダイの他の部分から
ポリマー溶液の中心へ送り出す。ポリマーおよびゲルが
この種の溶剤キャスチングに際して設置される凝固浴に
達した時点で、この構造体が硬化するのに伴いゲルはポ
リマーで囲まれる。あるいはもちろん、繊維末端をシー
ルしたのち繊維の長さ内へゲルを加圧下に添加すること
もできる。
【００１４】図４は壁構造全体が中空壁５２であるステ
ント５０を示す。特にステント５０は、図示したように
膨張した状態ではらせん形状をもつが、体腔内の部位へ
は膨張していない直線形状で送り込むことができるバル
ーン５４からなる中空の膨張式壁５２を含む。図１−３
に示すステントと同様にステント５０の壁５２は、たと
えば当技術分野で既知の半透膜を形成しうるポリマーか
ら構成される半透膜から製造される。その例には同様に
ポリアミド、ポリエステル、ポリウレタン、およびエチ
レンビニルアルコールが含まれるが、これらに限定され
ない。先に図１に関して述べたように、壁５２の内部に
は親水性材料が配置される。これは液体を吸収しうるも
のであり、これによりこの材料の体積が増大し、膨張を
達成する。壁５２の少なくとも一部を繊維強化材５６、
たとえばポリエステル、ナイロンまたはポリプロピレン
、好ましくはポリエステルで強化することもできる。 製造中に壁５２に強化材５６を付与する１手段は、構造
体の周りに繊維を編組し、次いで半透膜のオーバーコー
トを施すものである。この種の強化材はもちろんステン
ト５０にいっそう大きな強度を付与する。
【００１５】中空壁５２の内部には親水性材料が配置さ
れ、ステント５０は先に図１−３に関して述べたように
、体腔内の目的部位に配置される。同様に、適量の周囲
組織液が壁５２内へ拡散し、これにより親水性材料が膨
潤してステント５０を膨張させ、従ってこれがそのらせ
ん形状を確保し、体腔内壁に突き当たることにより適所
に自立滞在しうるのに十分な期間、目的位置におけるこ
の配置が送入手段によって維持される。もちろん膨張式
壁５２の製造に用いられる半透膜は、膨張した親水性材
料により内部に形成される圧力による破裂に耐えるのに
十分な強度のものでなければならない。
【００１６】図４に示すステント５０も徐放性ドラッグ
デリバリー用具として使用しうる。特に薬物を壁５２内
に上記親水性材料と共に配置することができ、薬物は半
透膜の壁構造を通して周囲組織内へ長期間にわたって放
出される。
【００１７】本発明の一例となる、現時点で好ましい形
態につき詳述したが、本発明の概念は他の各種形態およ
び用途が可能であり、特許請求の範囲の記載は先行技術
により制限されない限りこれらの概念を包含すると解す
べきである。
【図面の簡単な説明】
【図１】壁構造全体が膨張式バルーンからなる中空壁で
あるチューブ状ステントの、一部断面を含む透視図であ
る。
【図２】壁構造全体が編組された膨張性繊維からなる中
空壁である第２形態のチューブ状ステントの、一部断面
を含む立面図である。
【図３】壁構造が膨張性繊維の中空壁部分および中実繊
維の中実壁部分からなり、中空繊維および中実繊維の双
方が互いに編組された第３形態のチューブ状ステントの
、一部断面を含む立面図である。
【図４】壁構造全体が膨張式らせんからなる第４形態の
ステントの、一部断面を含む透視図である。
【符号の説明】
１０，２０，４０，５０　　ステント １２，２４，，４４，５２　　膨張式壁１６，２９　　
開口 １８，５４　　バルーン ２６　　中空繊維 ２８　　中実繊維 ３２　　親水性材料 ５６　　強化材

Claims (19)

    【特許請求の範囲】
  1. 【請求項１】　　少なくともその一部が半透膜から製造
    された中空壁である壁構造を含む、体腔内に配置するた
    めのステント。
  2. 【請求項２】　　中空壁の内部に、液体を吸収すること
    により体積が増大しうる親水性材料が配置された、請求
    項１に記載のステント。
  3. 【請求項３】　　親水性材料がゲルである、請求項２に
    記載のステント。
  4. 【請求項４】　　形状がチューブ状である、請求項２に
    記載のステント。
  5. 【請求項５】　　中空壁がバルーンからなる、請求項４
    に記載のステント。
  6. 【請求項６】　　中空壁を複数の半径方向開口が貫通す
    る、請求項５に記載のステント。
  7. 【請求項７】　　中空壁を複数の半径方向開口が貫通す
    る、請求項２に記載のステント。
  8. 【請求項８】　　中空壁が、互いに編組、製織、または
    巻織されることにより互いに保持された中空繊維からな
    る、請求項２に記載のステント。
  9. 【請求項９】　　壁構造がさらに、互いに編組、製織、
    または巻織されることにより中空繊維と共に保持された
    中実繊維を含む、請求項８に記載のステント。
  10. 【請求項１０】　　親水性材料と共に薬物が配置された
    、請求項２に記載のステント。
  11. 【請求項１１】　　親水性材料がゲルである、請求項１
    ０に記載のステント。
  12. 【請求項１２】　　中空壁がバルーンからなる、請求項
    １０に記載のステント。
  13. 【請求項１３】　　中空壁が、互いに編組、製織、また
    は巻織されることにより互いに保持された中空繊維から
    なる、請求項１０に記載のステント。
  14. 【請求項１４】　　壁構造がさらに、互いに編組、製織
    、または巻織されることにより中空繊維と共に保持され
    た中実繊維を含む、請求項１３に記載のステント。
  15. 【請求項１５】　　膨張した状態の形状がらせん形であ
    る、請求項２に記載のステント。
  16. 【請求項１６】　　中空壁がバルーンからなる、請求項
    １５に記載のステント。
  17. 【請求項１７】　　中空壁の少なくとも一部が強化され
    ている、請求項１６に記載のステント。
  18. 【請求項１８】　　親水性材料がゲルである、請求項１
    ５に記載のステント。
  19. 【請求項１９】　　親水性材料と共に薬物が配置された
    、請求項１８に記載のステント。
JP3016116A 1990-02-08 1991-02-07 膨張式ステント Expired - Fee Related JPH0773607B2 (ja)

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US477264 1990-02-08

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JPH0773607B2 JPH0773607B2 (ja) 1995-08-09

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EP (1) EP0441516B1 (ja)
JP (1) JPH0773607B2 (ja)
AT (1) ATE120377T1 (ja)
AU (1) AU621780B2 (ja)
CA (1) CA2035853C (ja)
DE (2) DE69108423T2 (ja)
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Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH11285537A (ja) * 1998-02-25 1999-10-19 Cordis Corp ワイヤ補強管プロテ―ゼ
US6723120B2 (en) 1997-04-15 2004-04-20 Advanced Cardiovascular Systems, Inc. Medicated porous metal prosthesis
US6805898B1 (en) 2000-09-28 2004-10-19 Advanced Cardiovascular Systems, Inc. Surface features of an implantable medical device
JP2007502135A (ja) * 2003-08-14 2007-02-08 ブルー・メディカル・デバイシーズ・ベスローテン・フェンノートシャップ 治療剤を含んで成る腔内人工器官
WO2011118499A1 (ja) * 2010-03-23 2011-09-29 テルモ株式会社 生体管腔用補修材
JP2013540464A (ja) * 2010-08-30 2013-11-07 サイナシス コーポレーション 副鼻腔開口部を拡張するため、および副鼻腔炎を治療するためのデバイスおよび方法
JP2014104088A (ja) * 2012-11-27 2014-06-09 Daikyo Kenko Kaihatsu Hiroshi Co Ltd 涙道用挿入具
USRE45744E1 (en) 2003-12-01 2015-10-13 Abbott Cardiovascular Systems Inc. Temperature controlled crimping
US9687263B2 (en) 2013-05-30 2017-06-27 SinuSys Corporation Devices and methods for inserting a sinus dilator
US10028851B2 (en) 1997-04-15 2018-07-24 Advanced Cardiovascular Systems, Inc. Coatings for controlling erosion of a substrate of an implantable medical device

Families Citing this family (410)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5843089A (en) 1990-12-28 1998-12-01 Boston Scientific Corporation Stent lining
US5674192A (en) * 1990-12-28 1997-10-07 Boston Scientific Corporation Drug delivery
US5545208A (en) * 1990-02-28 1996-08-13 Medtronic, Inc. Intralumenal drug eluting prosthesis
US6004346A (en) * 1990-02-28 1999-12-21 Medtronic, Inc. Intralumenal drug eluting prosthesis
EP0972535B1 (en) * 1991-09-12 2005-12-28 Advanced Cardiovascular Systems, Inc. Inflatable member having elastic expansion with limited range
US6515009B1 (en) 1991-09-27 2003-02-04 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US5811447A (en) 1993-01-28 1998-09-22 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US5366504A (en) * 1992-05-20 1994-11-22 Boston Scientific Corporation Tubular medical prosthesis
CA2079417C (en) 1991-10-28 2003-01-07 Lilip Lau Expandable stents and method of making same
US5215527A (en) * 1991-12-12 1993-06-01 Becton, Dickinson And Company Catheter introducer assembly
US5258042A (en) * 1991-12-16 1993-11-02 Henry Ford Health System Intravascular hydrogel implant
US5405378A (en) * 1992-05-20 1995-04-11 Strecker; Ernst P. Device with a prosthesis implantable in the body of a patient
DE4222380A1 (de) 1992-07-08 1994-01-13 Ernst Peter Prof Dr M Strecker In den Körper eines Patienten perkutan implantierbare Endoprothese
JP3739411B2 (ja) * 1992-09-08 2006-01-25 敬二 伊垣 脈管ステント及びその製造方法並びに脈管ステント装置
US5578075B1 (en) * 1992-11-04 2000-02-08 Daynke Res Inc Minimally invasive bioactivated endoprosthesis for vessel repair
DE4240177C2 (de) * 1992-11-30 1997-02-13 Ruesch Willy Ag Selbstexpandierender Stent für Hohlorgane
US5342348A (en) * 1992-12-04 1994-08-30 Kaplan Aaron V Method and device for treating and enlarging body lumens
US5419760A (en) * 1993-01-08 1995-05-30 Pdt Systems, Inc. Medicament dispensing stent for prevention of restenosis of a blood vessel
EP0691841B1 (en) * 1993-01-08 2002-05-29 Miravant Systems, Inc. Medicament dispensing stents
US6576008B2 (en) 1993-02-19 2003-06-10 Scimed Life Systems, Inc. Methods and device for inserting and withdrawing a two piece stent across a constricting anatomic structure
FR2701648B1 (fr) 1993-02-19 1995-03-31 Marian Devonec Prothèse destinée au traitement d'une lumière ou voie naturelle, notamment prothèse endo-uréthrale.
WO1994021196A2 (en) * 1993-03-18 1994-09-29 C.R. Bard, Inc. Endovascular stents
NL9300500A (nl) * 1993-03-22 1994-10-17 Industrial Res Bv Uitzetbare, holle huls voor het plaatselijk ondersteunen en/of versterken van een lichaamsvat, alsmede werkwijze voor het vervaardigen daarvan.
US20020055710A1 (en) * 1998-04-30 2002-05-09 Ronald J. Tuch Medical device for delivering a therapeutic agent and method of preparation
US5824048A (en) * 1993-04-26 1998-10-20 Medtronic, Inc. Method for delivering a therapeutic substance to a body lumen
US5464650A (en) * 1993-04-26 1995-11-07 Medtronic, Inc. Intravascular stent and method
AU6787194A (en) * 1993-05-11 1994-12-12 Target Therapeutics, Inc. Temporary inflatable intravascular prosthesis
US5480423A (en) * 1993-05-20 1996-01-02 Boston Scientific Corporation Prosthesis delivery
US5994341A (en) * 1993-07-19 1999-11-30 Angiogenesis Technologies, Inc. Anti-angiogenic Compositions and methods for the treatment of arthritis
NZ533467A (en) * 1993-07-19 2006-02-24 Angiotech Pharm Inc Anti-angiogenic compositions and methods of use
US5499994A (en) * 1993-07-30 1996-03-19 American Medical Systems, Inc. Dilation device for the urethra
DE4334140C2 (de) * 1993-10-07 1996-04-18 Angiomed Ag Stent und Vorrichtung mit Stent
DE59308451D1 (de) * 1993-10-20 1998-05-28 Schneider Europ Ag Endoprothese
US5476505A (en) * 1993-11-18 1995-12-19 Advanced Cardiovascular Systems, Inc. Coiled stent and delivery system
US5607444A (en) * 1993-12-02 1997-03-04 Advanced Cardiovascular Systems, Inc. Ostial stent for bifurcations
US5876418A (en) * 1994-01-13 1999-03-02 Angiomed Ag Device for providing a duct in a living body
US5817100A (en) * 1994-02-07 1998-10-06 Kabushikikaisya Igaki Iryo Sekkei Stent device and stent supplying system
ATE310839T1 (de) * 1994-04-29 2005-12-15 Scimed Life Systems Inc Stent mit kollagen
WO1995029646A1 (en) 1994-04-29 1995-11-09 Boston Scientific Corporation Medical prosthetic stent and method of manufacture
US5499995C1 (en) * 1994-05-25 2002-03-12 Paul S Teirstein Body passageway closure apparatus and method of use
US5857998A (en) * 1994-06-30 1999-01-12 Boston Scientific Corporation Stent and therapeutic delivery system
FR2722413B1 (fr) * 1994-07-13 1997-02-07 Marian Devonec Implant therapeutique destine au traitement cytoreducteur selectif de l'obstruction d'une lumiere ou voie naturelle d'un corps humain ou animal
US5891108A (en) * 1994-09-12 1999-04-06 Cordis Corporation Drug delivery stent
US5649977A (en) * 1994-09-22 1997-07-22 Advanced Cardiovascular Systems, Inc. Metal reinforced polymer stent
US5707385A (en) * 1994-11-16 1998-01-13 Advanced Cardiovascular Systems, Inc. Drug loaded elastic membrane and method for delivery
US5637113A (en) * 1994-12-13 1997-06-10 Advanced Cardiovascular Systems, Inc. Polymer film for wrapping a stent structure
DE9420877U1 (de) * 1994-12-29 1995-02-16 Freiburghaus, Andreas U., Dr.med., Stäfa Körper für rohrartige Durchgänge
USD380266S (en) * 1994-12-30 1997-06-24 Cook Incorporated Implantable, actively expandable stent
AU741137B2 (en) * 1995-02-22 2001-11-22 Menlo Care, Inc. Covered expanding mesh stent
EP0810845A2 (en) * 1995-02-22 1997-12-10 Menlo Care Inc. Covered expanding mesh stent
WO1996026682A1 (en) * 1995-02-27 1996-09-06 Instent, Inc. Hollow stent
US5556414A (en) * 1995-03-08 1996-09-17 Wayne State University Composite intraluminal graft
US6579314B1 (en) * 1995-03-10 2003-06-17 C.R. Bard, Inc. Covered stent with encapsulated ends
US6451047B2 (en) 1995-03-10 2002-09-17 Impra, Inc. Encapsulated intraluminal stent-graft and methods of making same
US6264684B1 (en) 1995-03-10 2001-07-24 Impra, Inc., A Subsidiary Of C.R. Bard, Inc. Helically supported graft
US5605696A (en) * 1995-03-30 1997-02-25 Advanced Cardiovascular Systems, Inc. Drug loaded polymeric material and method of manufacture
US20020198586A1 (en) 1995-04-12 2002-12-26 Kanji Inoue Appliance collapsible for insertion into a human organ and capable of resilient restoration
US6171326B1 (en) 1998-08-27 2001-01-09 Micrus Corporation Three dimensional, low friction vasoocclusive coil, and method of manufacture
US5645558A (en) * 1995-04-20 1997-07-08 Medical University Of South Carolina Anatomically shaped vasoocclusive device and method of making the same
US8790363B2 (en) * 1995-04-20 2014-07-29 DePuy Synthes Products, LLC Three dimensional, low friction vasoocclusive coil, and method of manufacture
US6638291B1 (en) 1995-04-20 2003-10-28 Micrus Corporation Three dimensional, low friction vasoocclusive coil, and method of manufacture
WO1996036297A1 (fr) 1995-05-19 1996-11-21 Kanji Inoue Instrument de transplantation, procede pour le courber et procede pour le transplanter
US6270520B1 (en) 1995-05-19 2001-08-07 Kanji Inoue Appliance to be implanted, method of collapsing the appliance to be implanted and method of using the appliance to be implanted
US7550005B2 (en) 1995-06-07 2009-06-23 Cook Incorporated Coated implantable medical device
US6774278B1 (en) * 1995-06-07 2004-08-10 Cook Incorporated Coated implantable medical device
US7896914B2 (en) * 1995-06-07 2011-03-01 Cook Incorporated Coated implantable medical device
US7611533B2 (en) * 1995-06-07 2009-11-03 Cook Incorporated Coated implantable medical device
US5758562A (en) * 1995-10-11 1998-06-02 Schneider (Usa) Inc. Process for manufacturing braided composite prosthesis
US6283951B1 (en) * 1996-10-11 2001-09-04 Transvascular, Inc. Systems and methods for delivering drugs to selected locations within the body
US5591195A (en) * 1995-10-30 1997-01-07 Taheri; Syde Apparatus and method for engrafting a blood vessel
US5788626A (en) * 1995-11-21 1998-08-04 Schneider (Usa) Inc Method of making a stent-graft covered with expanded polytetrafluoroethylene
US5871537A (en) 1996-02-13 1999-02-16 Scimed Life Systems, Inc. Endovascular apparatus
US5718159A (en) 1996-04-30 1998-02-17 Schneider (Usa) Inc. Process for manufacturing three-dimensional braided covered stent
US6592617B2 (en) * 1996-04-30 2003-07-15 Boston Scientific Scimed, Inc. Three-dimensional braided covered stent
US5733326A (en) * 1996-05-28 1998-03-31 Cordis Corporation Composite material endoprosthesis
US6027528A (en) * 1996-05-28 2000-02-22 Cordis Corporation Composite material endoprosthesis
US5820918A (en) * 1996-07-11 1998-10-13 Hercules Incorporated Medical devices containing in-situ generated medical compounds
US6060534A (en) 1996-07-11 2000-05-09 Scimed Life Systems, Inc. Medical devices comprising ionically and non-ionically crosslinked polymer hydrogels having improved mechanical properties
ZA9710342B (en) 1996-11-25 1998-06-10 Alza Corp Directional drug delivery stent and method of use.
US6117168A (en) 1996-12-31 2000-09-12 Scimed Life Systems, Inc. Multilayer liquid absorption and deformation devices
US5868719A (en) * 1997-01-15 1999-02-09 Boston Scientific Corporation Drug delivery balloon catheter device
US6494861B1 (en) 1997-01-15 2002-12-17 Boston Scientific Corporation Drug delivery system
US7027869B2 (en) 1998-01-07 2006-04-11 Asthmatx, Inc. Method for treating an asthma attack
US6200333B1 (en) 1997-04-07 2001-03-13 Broncus Technologies, Inc. Bronchial stenter
US7992572B2 (en) 1998-06-10 2011-08-09 Asthmatx, Inc. Methods of evaluating individuals having reversible obstructive pulmonary disease
US5972026A (en) 1997-04-07 1999-10-26 Broncus Technologies, Inc. Bronchial stenter having diametrically adjustable electrodes
US6283988B1 (en) 1997-04-07 2001-09-04 Broncus Technologies, Inc. Bronchial stenter having expandable electrodes
US6488673B1 (en) 1997-04-07 2002-12-03 Broncus Technologies, Inc. Method of increasing gas exchange of a lung
US6634363B1 (en) 1997-04-07 2003-10-21 Broncus Technologies, Inc. Methods of treating lungs having reversible obstructive pulmonary disease
US6273907B1 (en) 1997-04-07 2001-08-14 Broncus Technologies, Inc. Bronchial stenter
US8172897B2 (en) 1997-04-15 2012-05-08 Advanced Cardiovascular Systems, Inc. Polymer and metal composite implantable medical devices
US6273913B1 (en) 1997-04-18 2001-08-14 Cordis Corporation Modified stent useful for delivery of drugs along stent strut
US6776792B1 (en) 1997-04-24 2004-08-17 Advanced Cardiovascular Systems Inc. Coated endovascular stent
US6272370B1 (en) 1998-08-07 2001-08-07 The Regents Of University Of Minnesota MR-visible medical device for neurological interventions using nonlinear magnetic stereotaxis and a method imaging
GB9713624D0 (en) 1997-06-28 1997-09-03 Anson Medical Ltd Expandable device
ES2214600T3 (es) 1997-06-30 2004-09-16 Medex Holding Gmbh Implante intraluminal.
US7182727B2 (en) 1997-07-11 2007-02-27 A—Med Systems Inc. Single port cardiac support apparatus
US6123725A (en) * 1997-07-11 2000-09-26 A-Med Systems, Inc. Single port cardiac support apparatus
US6395026B1 (en) 1998-05-15 2002-05-28 A-Med Systems, Inc. Apparatus and methods for beating heart bypass surgery
US5899935A (en) * 1997-08-04 1999-05-04 Schneider (Usa) Inc. Balloon expandable braided stent with restraint
US7753950B2 (en) 1997-08-13 2010-07-13 Advanced Cardiovascular Systems, Inc. Stent and catheter assembly and method for treating bifurcations
US5941855A (en) * 1997-10-03 1999-08-24 Applied Medical Technology, Inc. Gastrostomy device package and method of assembly
US6273908B1 (en) 1997-10-24 2001-08-14 Robert Ndondo-Lay Stents
NL1007349C2 (nl) 1997-10-24 1999-04-27 Suyker Wilhelmus Joseph Leonardus Systeem voor het mechanisch vervaardigen van anastomoses tussen holle structuren; alsmede inrichting en applicator voor gebruik daarbij.
US6159165A (en) 1997-12-05 2000-12-12 Micrus Corporation Three dimensional spherical micro-coils manufactured from radiopaque nickel-titanium microstrand
US6136015A (en) 1998-08-25 2000-10-24 Micrus Corporation Vasoocclusive coil
US6241691B1 (en) 1997-12-05 2001-06-05 Micrus Corporation Coated superelastic stent
US6168570B1 (en) 1997-12-05 2001-01-02 Micrus Corporation Micro-strand cable with enhanced radiopacity
US6485514B1 (en) * 1997-12-12 2002-11-26 Supergen, Inc. Local delivery of therapeutic agents
US7921855B2 (en) 1998-01-07 2011-04-12 Asthmatx, Inc. Method for treating an asthma attack
US6395019B2 (en) 1998-02-09 2002-05-28 Trivascular, Inc. Endovascular graft
US6273917B1 (en) 1998-03-27 2001-08-14 Kanji Inoue Transplantation device
US20040254635A1 (en) 1998-03-30 2004-12-16 Shanley John F. Expandable medical device for delivery of beneficial agent
US6241762B1 (en) * 1998-03-30 2001-06-05 Conor Medsystems, Inc. Expandable medical device with ductile hinges
US7208011B2 (en) 2001-08-20 2007-04-24 Conor Medsystems, Inc. Implantable medical device with drug filled holes
US7208010B2 (en) 2000-10-16 2007-04-24 Conor Medsystems, Inc. Expandable medical device for delivery of beneficial agent
US6364858B1 (en) 1998-03-31 2002-04-02 Applied Medical Research, Inc. Collapsible internal bolster for gastrostomy device
US20070087028A1 (en) * 1998-04-16 2007-04-19 Robert Falotico Intraluminal devices for the prevention and treatment of vascular disease
US8029561B1 (en) 2000-05-12 2011-10-04 Cordis Corporation Drug combination useful for prevention of restenosis
US6168615B1 (en) 1998-05-04 2001-01-02 Micrus Corporation Method and apparatus for occlusion and reinforcement of aneurysms
US6463317B1 (en) 1998-05-19 2002-10-08 Regents Of The University Of Minnesota Device and method for the endovascular treatment of aneurysms
US6293960B1 (en) 1998-05-22 2001-09-25 Micrus Corporation Catheter with shape memory polymer distal tip for deployment of therapeutic devices
US7198635B2 (en) 2000-10-17 2007-04-03 Asthmatx, Inc. Modification of airways by application of energy
US8181656B2 (en) 1998-06-10 2012-05-22 Asthmatx, Inc. Methods for treating airways
US6171334B1 (en) 1998-06-17 2001-01-09 Advanced Cardiovascular Systems, Inc. Expandable stent and method of use
US6656218B1 (en) 1998-07-24 2003-12-02 Micrus Corporation Intravascular flow modifier and reinforcement device
US6165194A (en) 1998-07-24 2000-12-26 Micrus Corporation Intravascular flow modifier and reinforcement device
US6461380B1 (en) 1998-07-28 2002-10-08 Advanced Cardiovascular Systems, Inc. Stent configuration
US6149664A (en) * 1998-08-27 2000-11-21 Micrus Corporation Shape memory pusher introducer for vasoocclusive devices
US6500149B2 (en) 1998-08-31 2002-12-31 Deepak Gandhi Apparatus for deployment of micro-coil using a catheter
US6478773B1 (en) 1998-12-21 2002-11-12 Micrus Corporation Apparatus for deployment of micro-coil using a catheter
US6296622B1 (en) 1998-12-21 2001-10-02 Micrus Corporation Endoluminal device delivery system using axially recovering shape memory material
ATE335493T1 (de) * 1998-09-03 2006-09-15 Kerckhoff Klinik Ges Mit Besch 3-deazaadenosin zur vorbeugung der atherosklerose und mit transplantat assoziierten vaskulopathie
US6117104A (en) * 1998-09-08 2000-09-12 Advanced Cardiovascular Systems, Inc. Stent deployment system and method of use
EP1600125A3 (en) * 1998-09-29 2006-08-30 C.R.Bard, Inc. Coiled stent for drug delivery
US6358276B1 (en) * 1998-09-30 2002-03-19 Impra, Inc. Fluid containing endoluminal stent
US7018387B2 (en) * 1998-10-22 2006-03-28 Innovative Interventional Technologies B.V. Mechanical anastomosis system for hollow structures
US6537284B1 (en) 1998-10-29 2003-03-25 Kanji Inoue Device for guiding an appliance
US6293967B1 (en) 1998-10-29 2001-09-25 Conor Medsystems, Inc. Expandable medical device with ductile hinges
US6102932A (en) * 1998-12-15 2000-08-15 Micrus Corporation Intravascular device push wire delivery system
US6383204B1 (en) 1998-12-15 2002-05-07 Micrus Corporation Variable stiffness coil for vasoocclusive devices
US6835185B2 (en) 1998-12-21 2004-12-28 Micrus Corporation Intravascular device deployment mechanism incorporating mechanical detachment
US6165140A (en) 1998-12-28 2000-12-26 Micrus Corporation Composite guidewire
US6398803B1 (en) * 1999-02-02 2002-06-04 Impra, Inc., A Subsidiary Of C.R. Bard, Inc. Partial encapsulation of stents
US6221066B1 (en) 1999-03-09 2001-04-24 Micrus Corporation Shape memory segmented detachable coil
US6136021A (en) * 1999-03-23 2000-10-24 Cardiac Pacemakers, Inc. Expandable electrode for coronary venous leads
US6887235B2 (en) 1999-03-24 2005-05-03 Micrus Corporation Variable stiffness heating catheter
US6352531B1 (en) 1999-03-24 2002-03-05 Micrus Corporation Variable stiffness optical fiber shaft
US6464723B1 (en) 1999-04-22 2002-10-15 Advanced Cardiovascular Systems, Inc. Radiopaque stents
EP1095635A4 (en) 1999-05-06 2007-06-20 Kanji Inoue INSTRUMENTAL BANDER APPARATUS AND USE OF THE APPARATUS
US6290673B1 (en) 1999-05-20 2001-09-18 Conor Medsystems, Inc. Expandable medical device delivery system and method
IT1307263B1 (it) * 1999-08-05 2001-10-30 Sorin Biomedica Cardio Spa Stent per angioplastica con azione antagonista della restenosi,relativo corredo e componenti.
US6540774B1 (en) 1999-08-31 2003-04-01 Advanced Cardiovascular Systems, Inc. Stent design with end rings having enhanced strength and radiopacity
US7807211B2 (en) * 1999-09-03 2010-10-05 Advanced Cardiovascular Systems, Inc. Thermal treatment of an implantable medical device
US6585757B1 (en) 1999-09-15 2003-07-01 Advanced Cardiovascular Systems, Inc. Endovascular stent with radiopaque spine
EP1136044A1 (en) 1999-10-04 2001-09-26 Kanji Inoue Method of folding transplanting instrument and transplanting instrument
US6334868B1 (en) 1999-10-08 2002-01-01 Advanced Cardiovascular Systems, Inc. Stent cover
US6475235B1 (en) 1999-11-16 2002-11-05 Iowa-India Investments Company, Limited Encapsulated stent preform
US6251136B1 (en) 1999-12-08 2001-06-26 Advanced Cardiovascular Systems, Inc. Method of layering a three-coated stent using pharmacological and polymeric agents
US6602287B1 (en) 1999-12-08 2003-08-05 Advanced Cardiovascular Systems, Inc. Stent with anti-thrombogenic coating
US6702849B1 (en) 1999-12-13 2004-03-09 Advanced Cardiovascular Systems, Inc. Method of processing open-celled microcellular polymeric foams with controlled porosity for use as vascular grafts and stent covers
US6537311B1 (en) 1999-12-30 2003-03-25 Advanced Cardiovascular Systems, Inc. Stent designs for use in peripheral vessels
US6355058B1 (en) 1999-12-30 2002-03-12 Advanced Cardiovascular Systems, Inc. Stent with radiopaque coating consisting of particles in a binder
US6471721B1 (en) 1999-12-30 2002-10-29 Advanced Cardiovascular Systems, Inc. Vascular stent having increased radiopacity and method for making same
US7740637B2 (en) 2000-02-09 2010-06-22 Micrus Endovascular Corporation Apparatus and method for deployment of a therapeutic device using a catheter
DE10010074B4 (de) * 2000-02-28 2005-04-14 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Vorrichtung zur Befestigung und Verankerung von Herzklappenprothesen
US6953476B1 (en) 2000-03-27 2005-10-11 Neovasc Medical Ltd. Device and method for treating ischemic heart disease
US8251070B2 (en) 2000-03-27 2012-08-28 Asthmatx, Inc. Methods for treating airways
US6436132B1 (en) 2000-03-30 2002-08-20 Advanced Cardiovascular Systems, Inc. Composite intraluminal prostheses
US7875283B2 (en) * 2000-04-13 2011-01-25 Advanced Cardiovascular Systems, Inc. Biodegradable polymers for use with implantable medical devices
US8109994B2 (en) * 2003-01-10 2012-02-07 Abbott Cardiovascular Systems, Inc. Biodegradable drug delivery material for stent
US6527801B1 (en) 2000-04-13 2003-03-04 Advanced Cardiovascular Systems, Inc. Biodegradable drug delivery material for stent
JP2001309969A (ja) * 2000-04-28 2001-11-06 Gunze Ltd 人工硬膜
US8236048B2 (en) 2000-05-12 2012-08-07 Cordis Corporation Drug/drug delivery systems for the prevention and treatment of vascular disease
US6776796B2 (en) 2000-05-12 2004-08-17 Cordis Corportation Antiinflammatory drug and delivery device
US8252044B1 (en) 2000-11-17 2012-08-28 Advanced Bio Prosthestic Surfaces, Ltd. Device for in vivo delivery of bioactive agents and method of manufacture thereof
US6652579B1 (en) 2000-06-22 2003-11-25 Advanced Cardiovascular Systems, Inc. Radiopaque stent
US6506408B1 (en) * 2000-07-13 2003-01-14 Scimed Life Systems, Inc. Implantable or insertable therapeutic agent delivery device
US6709452B1 (en) * 2000-08-21 2004-03-23 Linvatec Biomaterial Oy Biodegradable surgical implants
US6652574B1 (en) 2000-09-28 2003-11-25 Vascular Concepts Holdings Limited Product and process for manufacturing a wire stent coated with a biocompatible fluoropolymer
US7261735B2 (en) 2001-05-07 2007-08-28 Cordis Corporation Local drug delivery devices and methods for maintaining the drug coatings thereon
US20020111590A1 (en) 2000-09-29 2002-08-15 Davila Luis A. Medical devices, drug coatings and methods for maintaining the drug coatings thereon
ATE343969T1 (de) 2000-09-29 2006-11-15 Cordis Corp Beschichtete medizinische geräte
EP1498084B1 (en) 2000-10-16 2014-06-18 Innovational Holdings, LLC Expandable medical device for delivery of beneficial agent
US6764507B2 (en) 2000-10-16 2004-07-20 Conor Medsystems, Inc. Expandable medical device with improved spatial distribution
US7104987B2 (en) 2000-10-17 2006-09-12 Asthmatx, Inc. Control system and process for application of energy to airway walls and other mediums
US7803149B2 (en) 2002-07-12 2010-09-28 Cook Incorporated Coated medical device
US6966917B1 (en) 2000-11-09 2005-11-22 Innovation Interventional Technologies B.V. Deformable connector for mechanically connecting hollow structures
US9107605B2 (en) * 2000-11-17 2015-08-18 Advanced Bio Prosthetic Surfaces, Ltd., A Wholly Owned Subsidiary Of Palmaz Scientific, Inc. Device for in vivo delivery of bioactive agents and method of manufacture thereof
JP4868565B2 (ja) * 2000-11-30 2012-02-01 株式会社 京都医療設計 血管用ステント
US7108655B2 (en) * 2001-01-23 2006-09-19 Abbeymoor Medical, Inc. Endourethral device and method
US20040073294A1 (en) 2002-09-20 2004-04-15 Conor Medsystems, Inc. Method and apparatus for loading a beneficial agent into an expandable medical device
US6964680B2 (en) * 2001-02-05 2005-11-15 Conor Medsystems, Inc. Expandable medical device with tapered hinge
DE10105592A1 (de) * 2001-02-06 2002-08-08 Achim Goepferich Platzhalter zur Arzneistofffreigabe in der Stirnhöhle
US20020119178A1 (en) * 2001-02-23 2002-08-29 Luc Levesque Drug eluting device for treating vascular diseases
US20020138131A1 (en) * 2001-03-20 2002-09-26 Solovay Kenneth S. Rail stent
US6913765B2 (en) * 2001-03-21 2005-07-05 Scimed Life Systems, Inc. Controlling resorption of bioresorbable medical implant material
DE10115740A1 (de) 2001-03-26 2002-10-02 Ulrich Speck Zubereitung für die Restenoseprophylaxe
US8182527B2 (en) 2001-05-07 2012-05-22 Cordis Corporation Heparin barrier coating for controlled drug release
US6981964B2 (en) 2001-05-22 2006-01-03 Boston Scientific Scimed, Inc. Draining bodily fluids with a stent
US8715312B2 (en) * 2001-07-20 2014-05-06 Microvention, Inc. Aneurysm treatment device and method of use
US7572288B2 (en) * 2001-07-20 2009-08-11 Microvention, Inc. Aneurysm treatment device and method of use
US8252040B2 (en) * 2001-07-20 2012-08-28 Microvention, Inc. Aneurysm treatment device and method of use
US7056338B2 (en) 2003-03-28 2006-06-06 Conor Medsystems, Inc. Therapeutic agent delivery device with controlled therapeutic agent release rates
US20030045923A1 (en) * 2001-08-31 2003-03-06 Mehran Bashiri Hybrid balloon expandable/self expanding stent
US7285304B1 (en) 2003-06-25 2007-10-23 Advanced Cardiovascular Systems, Inc. Fluid treatment of a polymeric coating on an implantable medical device
US7989018B2 (en) 2001-09-17 2011-08-02 Advanced Cardiovascular Systems, Inc. Fluid treatment of a polymeric coating on an implantable medical device
US6863683B2 (en) 2001-09-19 2005-03-08 Abbott Laboratoris Vascular Entities Limited Cold-molding process for loading a stent onto a stent delivery system
US6790223B2 (en) 2001-09-21 2004-09-14 Scimed Life Systems, Inc. Delivering a uretheral stent
DE60238422D1 (de) 2001-09-24 2011-01-05 Boston Scient Ltd Optimierte dosierung bei paclitaxelhaltigen stents
US7195640B2 (en) 2001-09-25 2007-03-27 Cordis Corporation Coated medical devices for the treatment of vulnerable plaque
US7108701B2 (en) 2001-09-28 2006-09-19 Ethicon, Inc. Drug releasing anastomosis devices and methods for treating anastomotic sites
US20030065382A1 (en) * 2001-10-02 2003-04-03 Fischell Robert E. Means and method for the treatment of coronary artery obstructions
CA2769574C (en) 2001-10-04 2014-12-23 Neovasc Medical Ltd. Flow reducing implant
US6814561B2 (en) * 2001-10-30 2004-11-09 Scimed Life Systems, Inc. Apparatus and method for extrusion of thin-walled tubes
US7597775B2 (en) * 2001-10-30 2009-10-06 Boston Scientific Scimed, Inc. Green fluoropolymer tube and endovascular prosthesis formed using same
US7041139B2 (en) 2001-12-11 2006-05-09 Boston Scientific Scimed, Inc. Ureteral stents and related methods
US6981985B2 (en) * 2002-01-22 2006-01-03 Boston Scientific Scimed, Inc. Stent bumper struts
US7060089B2 (en) * 2002-01-23 2006-06-13 Boston Scientific Scimed, Inc. Multi-layer stent
KR100956195B1 (ko) * 2002-02-01 2010-05-06 어리어드 파마슈티칼스, 인코포레이티드 인 함유 화합물 및 이의 용도
US6699273B2 (en) 2002-02-04 2004-03-02 Scimed Life Systems, Inc. Sleeve welding collar
US7785340B2 (en) * 2002-02-04 2010-08-31 Boston Scientific Scimed, Inc. Bonding sleeve for medical device
US8328877B2 (en) 2002-03-19 2012-12-11 Boston Scientific Scimed, Inc. Stent retention element and related methods
US6949125B2 (en) 2002-04-16 2005-09-27 Boston Scientific Scimed, Inc. Ureteral stent with end-effector and related methods
US7122048B2 (en) * 2002-05-03 2006-10-17 Scimed Life Systems, Inc. Hypotube endoluminal device
US20030216804A1 (en) * 2002-05-14 2003-11-20 Debeer Nicholas C. Shape memory polymer stent
AU2003219503A1 (en) * 2002-08-08 2004-02-25 Neovasc Medical Ltd. Geometric flow regulator
US20040127976A1 (en) * 2002-09-20 2004-07-01 Conor Medsystems, Inc. Method and apparatus for loading a beneficial agent into an expandable medical device
DE10244847A1 (de) 2002-09-20 2004-04-01 Ulrich Prof. Dr. Speck Medizinische Vorrichtung zur Arzneimittelabgabe
US6733536B1 (en) 2002-10-22 2004-05-11 Scimed Life Systems Male urethral stent device
US20040143321A1 (en) * 2002-11-08 2004-07-22 Conor Medsystems, Inc. Expandable medical device and method for treating chronic total occlusions with local delivery of an angiogenic factor
US20040142014A1 (en) * 2002-11-08 2004-07-22 Conor Medsystems, Inc. Method and apparatus for reducing tissue damage after ischemic injury
US7435255B1 (en) 2002-11-13 2008-10-14 Advnaced Cardiovascular Systems, Inc. Drug-eluting stent and methods of making
US7144422B1 (en) * 2002-11-13 2006-12-05 Advanced Cardiovascular Systems, Inc. Drug-eluting stent and methods of making the same
EP1560548A2 (en) * 2002-11-15 2005-08-10 GMP Cardiac Care, Inc. Rail stent-graft for repairing abdominal aortic aneurysm
US7758881B2 (en) 2004-06-30 2010-07-20 Advanced Cardiovascular Systems, Inc. Anti-proliferative and anti-inflammatory agent combination for treatment of vascular disorders with an implantable medical device
US8435550B2 (en) 2002-12-16 2013-05-07 Abbot Cardiovascular Systems Inc. Anti-proliferative and anti-inflammatory agent combination for treatment of vascular disorders with an implantable medical device
US7105018B1 (en) * 2002-12-30 2006-09-12 Advanced Cardiovascular Systems, Inc. Drug-eluting stent cover and method of use
US7150758B2 (en) 2003-03-06 2006-12-19 Boston Scientific Santa Rosa Corp. Kink resistant endovascular graft
WO2004087214A1 (en) 2003-03-28 2004-10-14 Conor Medsystems, Inc. Implantable medical device with beneficial agent concentration gradient
US7651529B2 (en) 2003-05-09 2010-01-26 Boston Scientific Scimed, Inc. Stricture retractor
US20040226556A1 (en) 2003-05-13 2004-11-18 Deem Mark E. Apparatus for treating asthma using neurotoxin
US7169179B2 (en) 2003-06-05 2007-01-30 Conor Medsystems, Inc. Drug delivery device and method for bi-directional drug delivery
US7186789B2 (en) * 2003-06-11 2007-03-06 Advanced Cardiovascular Systems, Inc. Bioabsorbable, biobeneficial polyester polymers for use in drug eluting stent coatings
US7632291B2 (en) 2003-06-13 2009-12-15 Trivascular2, Inc. Inflatable implant
US7785653B2 (en) 2003-09-22 2010-08-31 Innovational Holdings Llc Method and apparatus for loading a beneficial agent into an expandable medical device
BRPI0318479B1 (pt) * 2003-09-24 2015-06-16 Wael Mohamed Nabil Lotfy Dispositivo para controle de fluxo
US7198675B2 (en) 2003-09-30 2007-04-03 Advanced Cardiovascular Systems Stent mandrel fixture and method for selectively coating surfaces of a stent
US20060241682A1 (en) * 2003-12-08 2006-10-26 Kurz Daniel R Intravascular device push wire delivery system
US7258697B1 (en) 2003-12-22 2007-08-21 Advanced Cardiovascular Systems, Inc. Stent with anchors to prevent vulnerable plaque rupture during deployment
WO2005077013A2 (en) 2004-02-06 2005-08-25 Georgia Tech Research Corporation Surface directed cellular attachment
WO2005077304A1 (en) 2004-02-06 2005-08-25 Georgia Tech Research Corporation Load bearing biocompatible device
US20050214339A1 (en) 2004-03-29 2005-09-29 Yiwen Tang Biologically degradable compositions for medical applications
US8568469B1 (en) 2004-06-28 2013-10-29 Advanced Cardiovascular Systems, Inc. Stent locking element and a method of securing a stent on a delivery system
US8241554B1 (en) 2004-06-29 2012-08-14 Advanced Cardiovascular Systems, Inc. Method of forming a stent pattern on a tube
US7731890B2 (en) 2006-06-15 2010-06-08 Advanced Cardiovascular Systems, Inc. Methods of fabricating stents with enhanced fracture toughness
US8747878B2 (en) 2006-04-28 2014-06-10 Advanced Cardiovascular Systems, Inc. Method of fabricating an implantable medical device by controlling crystalline structure
US8778256B1 (en) 2004-09-30 2014-07-15 Advanced Cardiovascular Systems, Inc. Deformation of a polymer tube in the fabrication of a medical article
US8747879B2 (en) 2006-04-28 2014-06-10 Advanced Cardiovascular Systems, Inc. Method of fabricating an implantable medical device to reduce chance of late inflammatory response
US7971333B2 (en) 2006-05-30 2011-07-05 Advanced Cardiovascular Systems, Inc. Manufacturing process for polymetric stents
US7515970B2 (en) 2004-08-18 2009-04-07 Cardiac Pacemakers, Inc. Transeptal lead
US9283099B2 (en) 2004-08-25 2016-03-15 Advanced Cardiovascular Systems, Inc. Stent-catheter assembly with a releasable connection for stent retention
US7229471B2 (en) 2004-09-10 2007-06-12 Advanced Cardiovascular Systems, Inc. Compositions containing fast-leaching plasticizers for improved performance of medical devices
US7875233B2 (en) 2004-09-30 2011-01-25 Advanced Cardiovascular Systems, Inc. Method of fabricating a biaxially oriented implantable medical device
US8043553B1 (en) 2004-09-30 2011-10-25 Advanced Cardiovascular Systems, Inc. Controlled deformation of a polymer tube with a restraining surface in fabricating a medical article
US8173062B1 (en) 2004-09-30 2012-05-08 Advanced Cardiovascular Systems, Inc. Controlled deformation of a polymer tube in fabricating a medical article
US8535345B2 (en) 2004-10-07 2013-09-17 DePuy Synthes Products, LLC Vasoocclusive coil with biplex windings to improve mechanical properties
US20060167538A1 (en) * 2004-12-23 2006-07-27 Rucker Brian K Inflatable biliary stent
DE102005003632A1 (de) 2005-01-20 2006-08-17 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Katheter für die transvaskuläre Implantation von Herzklappenprothesen
US20060222596A1 (en) * 2005-04-01 2006-10-05 Trivascular, Inc. Non-degradable, low swelling, water soluble radiopaque hydrogel polymer
US7947207B2 (en) 2005-04-12 2011-05-24 Abbott Cardiovascular Systems Inc. Method for retaining a vascular stent on a catheter
US7763198B2 (en) 2005-04-12 2010-07-27 Abbott Cardiovascular Systems Inc. Method for retaining a vascular stent on a catheter
US7381048B2 (en) 2005-04-12 2008-06-03 Advanced Cardiovascular Systems, Inc. Stents with profiles for gripping a balloon catheter and molds for fabricating stents
US7396366B2 (en) * 2005-05-11 2008-07-08 Boston Scientific Scimed, Inc. Ureteral stent with conforming retention structure
US7291166B2 (en) 2005-05-18 2007-11-06 Advanced Cardiovascular Systems, Inc. Polymeric stent patterns
US20060292690A1 (en) * 2005-06-22 2006-12-28 Cesco Bioengineering Co., Ltd. Method of making cell growth surface
US7833259B2 (en) 2005-07-25 2010-11-16 Cook Incorporated Fenestrated endoluminal stent system
US7658880B2 (en) 2005-07-29 2010-02-09 Advanced Cardiovascular Systems, Inc. Polymeric stent polishing method and apparatus
US7297758B2 (en) 2005-08-02 2007-11-20 Advanced Cardiovascular Systems, Inc. Method for extending shelf-life of constructs of semi-crystallizable polymers
US7476245B2 (en) 2005-08-16 2009-01-13 Advanced Cardiovascular Systems, Inc. Polymeric stent patterns
US9248034B2 (en) 2005-08-23 2016-02-02 Advanced Cardiovascular Systems, Inc. Controlled disintegrating implantable medical devices
US7867547B2 (en) 2005-12-19 2011-01-11 Advanced Cardiovascular Systems, Inc. Selectively coating luminal surfaces of stents
US20070156230A1 (en) 2006-01-04 2007-07-05 Dugan Stephen R Stents with radiopaque markers
US7951185B1 (en) 2006-01-06 2011-05-31 Advanced Cardiovascular Systems, Inc. Delivery of a stent at an elevated temperature
US7964210B2 (en) 2006-03-31 2011-06-21 Abbott Cardiovascular Systems Inc. Degradable polymeric implantable medical devices with a continuous phase and discrete phase
US8303648B2 (en) * 2006-04-25 2012-11-06 Cook Medical Technologies Llc Artificial venous valve containing therapeutic agent
US8003156B2 (en) 2006-05-04 2011-08-23 Advanced Cardiovascular Systems, Inc. Rotatable support elements for stents
US7761968B2 (en) 2006-05-25 2010-07-27 Advanced Cardiovascular Systems, Inc. Method of crimping a polymeric stent
US20130325107A1 (en) 2006-05-26 2013-12-05 Abbott Cardiovascular Systems Inc. Stents With Radiopaque Markers
US7951194B2 (en) 2006-05-26 2011-05-31 Abbott Cardiovascular Sysetms Inc. Bioabsorbable stent with radiopaque coating
US8343530B2 (en) 2006-05-30 2013-01-01 Abbott Cardiovascular Systems Inc. Polymer-and polymer blend-bioceramic composite implantable medical devices
US7959940B2 (en) 2006-05-30 2011-06-14 Advanced Cardiovascular Systems, Inc. Polymer-bioceramic composite implantable medical devices
US7842737B2 (en) 2006-09-29 2010-11-30 Abbott Cardiovascular Systems Inc. Polymer blend-bioceramic composite implantable medical devices
US8486135B2 (en) 2006-06-01 2013-07-16 Abbott Cardiovascular Systems Inc. Implantable medical devices fabricated from branched polymers
US8034287B2 (en) 2006-06-01 2011-10-11 Abbott Cardiovascular Systems Inc. Radiation sterilization of medical devices
US8603530B2 (en) 2006-06-14 2013-12-10 Abbott Cardiovascular Systems Inc. Nanoshell therapy
US8048448B2 (en) 2006-06-15 2011-11-01 Abbott Cardiovascular Systems Inc. Nanoshells for drug delivery
US8535372B1 (en) 2006-06-16 2013-09-17 Abbott Cardiovascular Systems Inc. Bioabsorbable stent with prohealing layer
US8333000B2 (en) 2006-06-19 2012-12-18 Advanced Cardiovascular Systems, Inc. Methods for improving stent retention on a balloon catheter
US8017237B2 (en) 2006-06-23 2011-09-13 Abbott Cardiovascular Systems, Inc. Nanoshells on polymers
US9072820B2 (en) 2006-06-26 2015-07-07 Advanced Cardiovascular Systems, Inc. Polymer composite stent with polymer particles
US8128688B2 (en) 2006-06-27 2012-03-06 Abbott Cardiovascular Systems Inc. Carbon coating on an implantable device
US7794776B1 (en) 2006-06-29 2010-09-14 Abbott Cardiovascular Systems Inc. Modification of polymer stents with radiation
US7740791B2 (en) 2006-06-30 2010-06-22 Advanced Cardiovascular Systems, Inc. Method of fabricating a stent with features by blow molding
US10004584B2 (en) 2006-07-10 2018-06-26 First Quality Hygienic, Inc. Resilient intravaginal device
US8047980B2 (en) 2006-07-10 2011-11-01 Mcneil-Ppc, Inc. Method of treating urinary incontinence
US10219884B2 (en) 2006-07-10 2019-03-05 First Quality Hygienic, Inc. Resilient device
US8613698B2 (en) 2006-07-10 2013-12-24 Mcneil-Ppc, Inc. Resilient device
WO2008008794A2 (en) 2006-07-10 2008-01-17 Mc Neil-Ppc, Inc. Resilient device
US7823263B2 (en) 2006-07-11 2010-11-02 Abbott Cardiovascular Systems Inc. Method of removing stent islands from a stent
US7998404B2 (en) 2006-07-13 2011-08-16 Advanced Cardiovascular Systems, Inc. Reduced temperature sterilization of stents
US7757543B2 (en) 2006-07-13 2010-07-20 Advanced Cardiovascular Systems, Inc. Radio frequency identification monitoring of stents
US7794495B2 (en) 2006-07-17 2010-09-14 Advanced Cardiovascular Systems, Inc. Controlled degradation of stents
US7886419B2 (en) 2006-07-18 2011-02-15 Advanced Cardiovascular Systems, Inc. Stent crimping apparatus and method
US8016879B2 (en) 2006-08-01 2011-09-13 Abbott Cardiovascular Systems Inc. Drug delivery after biodegradation of the stent scaffolding
US9173733B1 (en) 2006-08-21 2015-11-03 Abbott Cardiovascular Systems Inc. Tracheobronchial implantable medical device and methods of use
US7923022B2 (en) 2006-09-13 2011-04-12 Advanced Cardiovascular Systems, Inc. Degradable polymeric implantable medical devices with continuous phase and discrete phase
EP2094241A4 (en) * 2006-11-14 2013-04-17 Ariad Pharma Inc ORAL FORMULATIONS
CN101547665A (zh) * 2006-12-07 2009-09-30 马林克罗特公司 用于局部药物输送的医疗设备
US8099849B2 (en) 2006-12-13 2012-01-24 Abbott Cardiovascular Systems Inc. Optimizing fracture toughness of polymeric stent
WO2008098926A1 (en) * 2007-02-13 2008-08-21 Cinvention Ag Reservoir implants and stents
EP2120807A2 (en) * 2007-02-13 2009-11-25 Cinvention Ag Degradable reservoir implants
JP5271288B2 (ja) 2007-03-15 2013-08-21 オーソ−スペース リミテッド プロテーゼ装置およびその使用方法
US8262723B2 (en) 2007-04-09 2012-09-11 Abbott Cardiovascular Systems Inc. Implantable medical devices fabricated from polymer blends with star-block copolymers
US7896915B2 (en) 2007-04-13 2011-03-01 Jenavalve Technology, Inc. Medical device for treating a heart valve insufficiency
US8087923B1 (en) 2007-05-18 2012-01-03 C. R. Bard, Inc. Extremely thin-walled ePTFE
US7829008B2 (en) 2007-05-30 2010-11-09 Abbott Cardiovascular Systems Inc. Fabricating a stent from a blow molded tube
US9149610B2 (en) 2007-05-31 2015-10-06 Abbott Cardiovascular Systems Inc. Method and apparatus for improving delivery of an agent to a kidney
US8216209B2 (en) 2007-05-31 2012-07-10 Abbott Cardiovascular Systems Inc. Method and apparatus for delivering an agent to a kidney
US9364586B2 (en) 2007-05-31 2016-06-14 Abbott Cardiovascular Systems Inc. Method and apparatus for improving delivery of an agent to a kidney
US9144509B2 (en) 2007-05-31 2015-09-29 Abbott Cardiovascular Systems Inc. Method and apparatus for delivering an agent to a kidney
US7959857B2 (en) 2007-06-01 2011-06-14 Abbott Cardiovascular Systems Inc. Radiation sterilization of medical devices
US8202528B2 (en) 2007-06-05 2012-06-19 Abbott Cardiovascular Systems Inc. Implantable medical devices with elastomeric block copolymer coatings
US8293260B2 (en) 2007-06-05 2012-10-23 Abbott Cardiovascular Systems Inc. Elastomeric copolymer coatings containing poly (tetramethyl carbonate) for implantable medical devices
US8425591B1 (en) 2007-06-11 2013-04-23 Abbott Cardiovascular Systems Inc. Methods of forming polymer-bioceramic composite medical devices with bioceramic particles
US8048441B2 (en) 2007-06-25 2011-11-01 Abbott Cardiovascular Systems, Inc. Nanobead releasing medical devices
CN105943208B (zh) 2007-06-25 2019-02-15 微仙美国有限公司 自扩展假体
US7901452B2 (en) 2007-06-27 2011-03-08 Abbott Cardiovascular Systems Inc. Method to fabricate a stent having selected morphology to reduce restenosis
US7955381B1 (en) 2007-06-29 2011-06-07 Advanced Cardiovascular Systems, Inc. Polymer-bioceramic composite implantable medical device with different types of bioceramic particles
EP2182854B1 (en) 2007-08-17 2019-12-11 Micrus Endovascular Corporation A twisted primary coil for vascular therapy
US8226701B2 (en) 2007-09-26 2012-07-24 Trivascular, Inc. Stent and delivery system for deployment thereof
US8663309B2 (en) 2007-09-26 2014-03-04 Trivascular, Inc. Asymmetric stent apparatus and method
US8066755B2 (en) 2007-09-26 2011-11-29 Trivascular, Inc. System and method of pivoted stent deployment
AU2008308474B2 (en) 2007-10-04 2014-07-24 Trivascular, Inc. Modular vascular graft for low profile percutaneous delivery
US8328861B2 (en) 2007-11-16 2012-12-11 Trivascular, Inc. Delivery system and method for bifurcated graft
US8083789B2 (en) 2007-11-16 2011-12-27 Trivascular, Inc. Securement assembly and method for expandable endovascular device
KR100988816B1 (ko) * 2008-01-29 2010-10-20 신경민 담즙관용 이중 피막형 스텐트
US8483831B1 (en) 2008-02-15 2013-07-09 Holaira, Inc. System and method for bronchial dilation
ES2903231T3 (es) 2008-02-26 2022-03-31 Jenavalve Tech Inc Stent para el posicionamiento y anclaje de una prótesis valvular en un sitio de implantación en el corazón de un paciente
US9044318B2 (en) 2008-02-26 2015-06-02 Jenavalve Technology Gmbh Stent for the positioning and anchoring of a valvular prosthesis
US8196279B2 (en) 2008-02-27 2012-06-12 C. R. Bard, Inc. Stent-graft covering process
US8846777B2 (en) * 2008-04-22 2014-09-30 The Regents Of The University Of Colorado, A Body Corporate Thiol-vinyl and thiol-yne systems for shape memory polymers
US8603123B2 (en) 2008-04-28 2013-12-10 Urotech, Inc. Benign prostatic hyperplasia surgical system featuring mechanical coring probe with live aspiration
AU2009244058B2 (en) 2008-05-09 2015-07-02 Nuvaira, Inc Systems, assemblies, and methods for treating a bronchial tree
US8192500B2 (en) 2008-12-12 2012-06-05 Boston Scientific Scimed, Inc. Ureteral stent
US8512272B2 (en) 2008-12-22 2013-08-20 Boston Scientific Scimed, Inc. Ureteral stent
US20100303882A1 (en) * 2009-05-26 2010-12-02 Mallinckrodt Inc. Medical Devices for Localized Drug Delivery
US9283305B2 (en) * 2009-07-09 2016-03-15 Medtronic Vascular, Inc. Hollow tubular drug eluting medical devices
US8381774B2 (en) * 2009-09-20 2013-02-26 Medtronic Vascular, Inc. Methods for loading a drug eluting medical device
US8828474B2 (en) 2009-09-20 2014-09-09 Medtronic Vascular, Inc. Apparatus and methods for loading a drug eluting medical device
US8678046B2 (en) 2009-09-20 2014-03-25 Medtronic Vascular, Inc. Apparatus and methods for loading a drug eluting medical device
US20110070358A1 (en) * 2009-09-20 2011-03-24 Medtronic Vascular, Inc. Method of forming hollow tubular drug eluting medical devices
WO2011056684A2 (en) 2009-10-27 2011-05-12 Innovative Pulmonary Solutions, Inc. Delivery devices with coolable energy emitting assemblies
US9149328B2 (en) 2009-11-11 2015-10-06 Holaira, Inc. Systems, apparatuses, and methods for treating tissue and controlling stenosis
US8911439B2 (en) 2009-11-11 2014-12-16 Holaira, Inc. Non-invasive and minimally invasive denervation methods and systems for performing the same
US8568471B2 (en) 2010-01-30 2013-10-29 Abbott Cardiovascular Systems Inc. Crush recoverable polymer scaffolds
US8808353B2 (en) 2010-01-30 2014-08-19 Abbott Cardiovascular Systems Inc. Crush recoverable polymer scaffolds having a low crossing profile
JP2013526388A (ja) 2010-05-25 2013-06-24 イエナバルブ テクノロジー インク 人工心臓弁、及び人工心臓弁とステントを備える経カテーテル搬送体内プロテーゼ
US8333801B2 (en) 2010-09-17 2012-12-18 Medtronic Vascular, Inc. Method of Forming a Drug-Eluting Medical Device
US8616040B2 (en) 2010-09-17 2013-12-31 Medtronic Vascular, Inc. Method of forming a drug-eluting medical device
US8632846B2 (en) 2010-09-17 2014-01-21 Medtronic Vascular, Inc. Apparatus and methods for loading a drug eluting medical device
JP2014522263A (ja) 2011-05-11 2014-09-04 マイクロベンション インコーポレイテッド 内腔を閉塞するためのデバイス
US9155543B2 (en) 2011-05-26 2015-10-13 Cartiva, Inc. Tapered joint implant and related tools
US8726483B2 (en) 2011-07-29 2014-05-20 Abbott Cardiovascular Systems Inc. Methods for uniform crimping and deployment of a polymer scaffold
US9289307B2 (en) 2011-10-18 2016-03-22 Ortho-Space Ltd. Prosthetic devices and methods for using same
EP2819740A4 (en) 2012-02-29 2015-11-25 Sinusys Corp DEVICES AND METHOD FOR DILATING A PARANASAL SINUS OPENING AND FOR TREATING SINUSITIS
US8992595B2 (en) 2012-04-04 2015-03-31 Trivascular, Inc. Durable stent graft with tapered struts and stable delivery methods and devices
US9498363B2 (en) 2012-04-06 2016-11-22 Trivascular, Inc. Delivery catheter for endovascular device
US8998977B2 (en) 2012-04-13 2015-04-07 Medtronic Vascular, Inc. Hollow drug-filled stent and method of forming hollow drug-filled stent
US9770293B2 (en) 2012-06-04 2017-09-26 Boston Scientific Scimed, Inc. Systems and methods for treating tissue of a passageway within a body
WO2014018153A1 (en) 2012-07-24 2014-01-30 Boston Scientific Scimed, Inc. Electrodes for tissue treatment
US9272132B2 (en) 2012-11-02 2016-03-01 Boston Scientific Scimed, Inc. Medical device for treating airways and related methods of use
US9283374B2 (en) 2012-11-05 2016-03-15 Boston Scientific Scimed, Inc. Devices and methods for delivering energy to body lumens
US9498356B2 (en) 2012-12-19 2016-11-22 Cook Medical Technologies, LLC Flexible stent and delivery system
US9398933B2 (en) 2012-12-27 2016-07-26 Holaira, Inc. Methods for improving drug efficacy including a combination of drug administration and nerve modulation
US9486340B2 (en) 2013-03-14 2016-11-08 Medtronic Vascular, Inc. Method for manufacturing a stent and stent manufactured thereby
EP3335658B1 (en) 2013-08-09 2020-04-22 Boston Scientific Scimed, Inc. Expandable catheter
JP6563394B2 (ja) 2013-08-30 2019-08-21 イェーナヴァルヴ テクノロジー インコーポレイテッド 人工弁のための径方向に折り畳み自在のフレーム及び当該フレームを製造するための方法
US9433763B2 (en) 2013-09-27 2016-09-06 Acclarent, Inc. Sinus wall implant
US9510976B2 (en) 2014-04-29 2016-12-06 Abbott Cardiovascular Systems Inc. Devices and methods for treatment of the Eustachian tube and sinus cavity
US9763814B2 (en) 2014-10-24 2017-09-19 Cook Medical Technologies Llc Elongate medical device
US10166126B2 (en) 2014-12-08 2019-01-01 Boston Scientific Scimed, Inc. Inflatable balloon stent
US9999527B2 (en) 2015-02-11 2018-06-19 Abbott Cardiovascular Systems Inc. Scaffolds having radiopaque markers
AU2016243659B2 (en) 2015-03-31 2020-04-23 Cartiva, Inc. Hydrogel implants with porous materials and methods
CA2981064C (en) 2015-03-31 2024-01-02 Cartiva, Inc. Carpometacarpal (cmc) implants and methods
AU2016248062B2 (en) 2015-04-14 2020-01-23 Cartiva, Inc. Tooling for creating tapered opening in tissue and related methods
EP4403138A3 (en) 2015-05-01 2024-10-09 JenaValve Technology, Inc. Device and method with reduced pacemaker rate in heart valve replacement
US9700443B2 (en) 2015-06-12 2017-07-11 Abbott Cardiovascular Systems Inc. Methods for attaching a radiopaque marker to a scaffold
AU2016308061B2 (en) * 2015-08-17 2018-08-16 Boston Scientific Scimed, Inc. Radioactive stent
WO2017031065A1 (en) * 2015-08-17 2017-02-23 Boston Scientific Scimed, Inc. Radioactive stent
US10596330B2 (en) 2015-08-26 2020-03-24 Medtronic Xomed, Inc. Resorbable, drug-eluting submucosal turbinate implant device and method
US10959761B2 (en) 2015-09-18 2021-03-30 Ortho-Space Ltd. Intramedullary fixated subacromial spacers
US10130465B2 (en) 2016-02-23 2018-11-20 Abbott Cardiovascular Systems Inc. Bifurcated tubular graft for treating tricuspid regurgitation
CN109475419B (zh) 2016-05-13 2021-11-09 耶拿阀门科技股份有限公司 用于通过引导鞘和装载系统来递送心脏瓣膜假体的心脏瓣膜假体递送系统和方法
US11197754B2 (en) 2017-01-27 2021-12-14 Jenavalve Technology, Inc. Heart valve mimicry
US11045981B2 (en) 2017-01-30 2021-06-29 Ortho-Space Ltd. Processing machine and methods for processing dip-molded articles
KR102471885B1 (ko) 2018-04-09 2022-11-28 보스톤 싸이엔티픽 싸이메드 인코포레이티드 스텐트
US10575973B2 (en) 2018-04-11 2020-03-03 Abbott Cardiovascular Systems Inc. Intravascular stent having high fatigue performance
CA3127324A1 (en) 2019-01-23 2020-07-30 Neovasc Medical Ltd. Covered flow modifying apparatus
CN116801841A (zh) 2020-12-02 2023-09-22 波士顿科学国际有限公司 具有改进的部署特性的支架

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4237893A (en) * 1979-11-28 1980-12-09 Alza Corporation Cervical dilator
JPS59501345A (ja) * 1982-07-26 1984-08-02 ヘルス・プロダクツ・リサ−チ，インコ−ポレイテツド 頚状部拡張器具

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1887526A (en) * 1931-11-02 1932-11-15 Joseph M Spielberg Medical tampon
US4258704A (en) * 1978-08-30 1981-03-31 Johnson & Johnson Body orifice accessory
SE424045B (sv) * 1979-01-12 1982-06-28 Tesi Ab Kateter
SE445884B (sv) * 1982-04-30 1986-07-28 Medinvent Sa Anordning for implantation av en rorformig protes
SU1069826A1 (ru) * 1982-09-17 1984-01-30 Запорожский медицинский институт Эндотрахеальна трубка
US4503569A (en) * 1983-03-03 1985-03-12 Dotter Charles T Transluminally placed expandable graft prosthesis
US4610688A (en) * 1983-04-04 1986-09-09 Pfizer Hospital Products Group, Inc. Triaxially-braided fabric prosthesis
GB8412007D0 (en) * 1984-05-10 1984-06-13 Secr Defence Hydrophilic water-swellable graft copolymer
US4911691A (en) * 1984-09-21 1990-03-27 Menlo Care, Inc. Assembly for adminstering IV solution
US4580568A (en) * 1984-10-01 1986-04-08 Cook, Incorporated Percutaneous endovascular stent and method for insertion thereof
US4733665C2 (en) * 1985-11-07 2002-01-29 Expandable Grafts Partnership Expandable intraluminal graft and method and apparatus for implanting an expandable intraluminal graft
DE3786721D1 (de) * 1986-02-24 1993-09-02 Fischell Robert Vorrichtung zum aufweisen von blutgefaessen, sowie system zu deren einfuehrung.
JPH088933B2 (ja) * 1987-07-10 1996-01-31 日本ゼオン株式会社 カテ−テル
US4994047A (en) * 1988-05-06 1991-02-19 Menlo Care, Inc. Multi-layer cannula structure

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4237893A (en) * 1979-11-28 1980-12-09 Alza Corporation Cervical dilator
JPS59501345A (ja) * 1982-07-26 1984-08-02 ヘルス・プロダクツ・リサ−チ，インコ−ポレイテツド 頚状部拡張器具

Cited By (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6723120B2 (en) 1997-04-15 2004-04-20 Advanced Cardiovascular Systems, Inc. Medicated porous metal prosthesis
US10028851B2 (en) 1997-04-15 2018-07-24 Advanced Cardiovascular Systems, Inc. Coatings for controlling erosion of a substrate of an implantable medical device
JPH11285537A (ja) * 1998-02-25 1999-10-19 Cordis Corp ワイヤ補強管プロテ―ゼ
US6805898B1 (en) 2000-09-28 2004-10-19 Advanced Cardiovascular Systems, Inc. Surface features of an implantable medical device
US7335314B2 (en) 2000-09-28 2008-02-26 Advanced Cardiovascular Systems Inc. Method of making an implantable medical device
JP2007502135A (ja) * 2003-08-14 2007-02-08 ブルー・メディカル・デバイシーズ・ベスローテン・フェンノートシャップ 治療剤を含んで成る腔内人工器官
USRE45744E1 (en) 2003-12-01 2015-10-13 Abbott Cardiovascular Systems Inc. Temperature controlled crimping
CN102711675A (zh) * 2010-03-23 2012-10-03 泰尔茂株式会社 生物体管腔用修补材料
WO2011118499A1 (ja) * 2010-03-23 2011-09-29 テルモ株式会社 生体管腔用補修材
JP2013540464A (ja) * 2010-08-30 2013-11-07 サイナシス コーポレーション 副鼻腔開口部を拡張するため、および副鼻腔炎を治療するためのデバイスおよび方法
US9629644B2 (en) 2010-08-30 2017-04-25 SinuSys Corporation Devices and methods for dilating a paranasal sinus opening and for treating sinusitis
JP2014104088A (ja) * 2012-11-27 2014-06-09 Daikyo Kenko Kaihatsu Hiroshi Co Ltd 涙道用挿入具
US9687263B2 (en) 2013-05-30 2017-06-27 SinuSys Corporation Devices and methods for inserting a sinus dilator

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AU621780B2 (en) 1992-03-19
JPH0773607B2 (ja) 1995-08-09
EP0441516A2 (en) 1991-08-14
US5234456A (en) 1993-08-10
EP0441516A3 (en) 1992-08-05
CA2035853C (en) 1995-02-07
DE69108423T2 (de) 1995-07-27
IE65798B1 (en) 1995-11-15
DE9101344U1 (de) 1991-06-06
IE910398A1 (en) 1991-08-14
ES2071207T3 (es) 1995-06-16
ATE120377T1 (de) 1995-04-15
EP0441516B1 (en) 1995-03-29
AU7088791A (en) 1991-08-29
DE69108423D1 (de) 1995-05-04
DK0441516T3 (da) 1995-06-12

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