JPH0248517A - Hair tonic - Google Patents

Hair tonic

Info

Publication number
JPH0248517A
JPH0248517A JP63198888A JP19888888A JPH0248517A JP H0248517 A JPH0248517 A JP H0248517A JP 63198888 A JP63198888 A JP 63198888A JP 19888888 A JP19888888 A JP 19888888A JP H0248517 A JPH0248517 A JP H0248517A
Authority
JP
Japan
Prior art keywords
chinensis
surfactants
hair
extract
japonica
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP63198888A
Other languages
Japanese (ja)
Other versions
JP2814085B2 (en
Inventor
Hisayuki Komazaki
駒崎 久幸
Kiyoshi Miyazawa
清 宮澤
Jiyoutarou Nakanishi
城太郎 仲西
Reiji Miyahara
令二 宮原
Keiichi Uchikawa
内川 恵一
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shiseido Co Ltd
Original Assignee
Shiseido Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
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Application filed by Shiseido Co Ltd filed Critical Shiseido Co Ltd
Priority to JP63198888A priority Critical patent/JP2814085B2/en
Publication of JPH0248517A publication Critical patent/JPH0248517A/en
Application granted granted Critical
Publication of JP2814085B2 publication Critical patent/JP2814085B2/en
Anticipated expiration legal-status Critical
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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q7/00Preparations for affecting hair growth
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9728Fungi, e.g. yeasts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9741Pteridophyta [ferns]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9789Magnoliopsida [dicotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9794Liliopsida [monocotyledons]

Abstract

PURPOSE:To obtain a hair tonic, containing one or more extracts of crude drugs or further one or more surfactants and excellent in promoting effects on prevention of depilation, production, growth of hair, etc. CONSTITUTION:The objective substance obtained by containing one or more extracts of crude drugs or further one or more surfactants as essential ingredients, mixing the ingredients with normally used ingredients and preparing a formulation according to a conventional method. The amounts of the ingredients are 0.005-10wt.% extracts of the crude drugs expressed in terms of solid substances and 0.001-10wt.% surfactants. One or more selected from Firmiania platanifolia Schott et Endl., Tamarindus indica L., Prumus mume Sieb. et Zucc., Uritica thunbergiana Sieb. et Zucc., Microsorium fortunei (Moore) Ching, Astragali Radix, yellow Meswax, Puerariae Radix, dianthi herba, Cinnamon bark, acanthopanacis cortex, cusso, Schiandrae Fructus, Magnolia kobus, Thuja orientalis, cnidii rhizoma, Aurantii Nobilis Pericarpium, Ipecacuanhae Radix, Juglans regia L. var. orientis (Dode) Kitamura, Artemisia apiacea Hance, Zynthoxyli Fructus, Ganoderma lucidum Karst., calami rhizoma, Berberis thunbergii DC., Betula platyphylla Sukatchev. var. japonica Hara, elm tree, alpiniae officinarum rhizoma, salicaceae folium, Akebiae fructus, psoraleae semen, persicae folium, lilii bulbus, nelumbinis fructus, etc., are used as the crude drugs.

Description

【発明の詳細な説明】 [産業上の利用分野] 本発明は、新規にして、かつ安全なる生薬抽出物または
、生薬抽出物と界面活性剤とを含有することにより、脱
毛防止、発毛、育毛などを促進する効果に優れた養毛料
に関するものである。
Detailed Description of the Invention [Industrial Application Field] The present invention contains novel and safe crude drug extracts or crude drug extracts and surfactants to prevent hair loss, hair growth, The present invention relates to a hair nourishing agent that is highly effective in promoting hair growth.

[従来の技術] 従来より、各種薬剤を配合した養毛料が知られている。[Conventional technology] BACKGROUND ART Hair nourishing agents containing various drugs have been known.

例えば、ビタミンB等のビタミン類、メチオニンなどの
アミノ酸類、アセチルコリン誘導体などの血管拡張剤、
紫根エキスなどの抗炎症剤、エストラジオールなどの女
性ホルモン剤、セファランチンなどの皮膚機能亢進剤な
どが配合され、脱毛症の予防及び治療に用いられている
For example, vitamins such as vitamin B, amino acids such as methionine, vasodilators such as acetylcholine derivatives,
It contains anti-inflammatory agents such as purple root extract, female hormones such as estradiol, and skin function enhancers such as cephalanthine, and is used to prevent and treat alopecia.

しかしながら、従来の養毛料はフケ、カユミ、脱毛など
の予防及び改善に有効で、発毛や育毛を促進するとされ
ているが、いまだ満足すべき効果を発揮するものは得ら
れていない。
However, although conventional hair nourishing agents are said to be effective in preventing and improving dandruff, itching, hair loss, etc., and to promote hair growth and hair growth, no product that exhibits satisfactory effects has yet been obtained.

[発明が解決しようとする課題] 本発明者らは脱毛防止、発毛等に有効で、安全性に優れ
た養毛料について、鋭意研究した結果、特定の生薬抽出
物の一種または二種以上、またはこれら特定の生薬抽出
物の一種または二種以上と、特定の界面活性剤とを含有
することによりこの課題を解決しうろことを見出し、本
発明を完成するに至った。
[Problems to be Solved by the Invention] As a result of intensive research into hair nourishing agents that are effective for hair loss prevention, hair growth, etc. and excellent in safety, the present inventors have found that one or more specific crude drug extracts, Alternatively, the present inventors have discovered that this problem can be solved by containing one or more of these specific crude drug extracts and a specific surfactant, and have completed the present invention.

[課題を解決するための手段] すなわち請求項1記載の発明は、アオギリ、アンマロク
、ウバイ、イラクサ、オオクリハラン、オオギ、オウロ
、カッコン、グバク、ケイヒ、ゲドクシ、ゴカヒ、コソ
ウ、ゴミシ、コブシ、コノテガシワ、サンキュウ、チン
ピ、テウチグルミ、セイコウ、サッシヨウ、ドクヨウイ
ッシカ、ショウブ、ショウバク、シラカバ、ニレ、リョ
ウキョウ、リュウヨウ、ヨチシ、ホコッシ、トウヨウ、
ヒャクゴウ、レン、モクセイ、ハンミョウ、フヒョウ、
マクワウリ、ハクヨウ、ハンゲ、バクセン、ハクショウ
、ハクヨウからなる群から選ばれる生薬抽出物の一種又
は二種以上を含有してなる養毛料である。
[Means for Solving the Problem] That is, the invention according to claim 1 is directed to the following: Aogiri, Anmaroku, Ubai, Nettle, Ookuriharan, Ogi, Ouro, Kakkon, Gubaku, Keihi, Gedokushi, Gokahi, Kosou, Gomish, Kobushi, Konotegashiwa, Red-bellied, Chinpi, Teuchigurumi, Seikou, Sasshiyou, Dokuyoishika, Calamus, Shobu, Birch, Elm, Ryokyo, Ryuyou, Yochishi, Hokosshi, Touyou,
Hyakugou, Wren, Osmanthus, Hanmyo, Fuhyou,
This is a hair nourishment containing one or more crude drug extracts selected from the group consisting of Cucumber, Cucumber, Cucumber, Baxcens, Cucumber, and Cucumber.

請求項2記載の発明は、請求項1記載の生薬の抽出物の
一種又は二種以上と、アニオン性界面活性剤の一種又は
二種以上と、アニオン界面活性剤以外で分子内に窒素原
子を有する界面活性剤の一種又は二種以上とを含有する
ことを特徴とする養毛料である。
The invention according to claim 2 comprises one or more extracts of the crude drug according to claim 1, one or more anionic surfactants, and a nitrogen atom in the molecule other than the anionic surfactant. It is a hair nourishing agent characterized by containing one or more types of surfactants.

請求項3記載の発明は、請求項1記載の生薬の抽出物の
一種又は二種以上と、両性界面活性剤と半極性界面活性
剤の一種または二種以上と、分子内に窒素原子を有する
非イオン界面活性剤の一種または二種以上とを含有する
ことを特徴とする養毛料である。
The invention according to claim 3 is characterized in that one or more extracts of the crude drug according to claim 1, one or more amphoteric surfactants and semipolar surfactants, and a nitrogen atom in the molecule. This hair nourishing agent is characterized by containing one or more nonionic surfactants.

請求項4記載の発明は、請求項1記載の生薬の抽出物の
一種又は二種以上と、アミンオキシドとを含有すること
を特徴とする養毛料である。
The invention according to claim 4 is a hair nourishing agent, characterized in that it contains one or more extracts of the crude drug according to claim 1 and an amine oxide.

以下、本発明の構成について詳述する。Hereinafter, the configuration of the present invention will be explained in detail.

本発明で用いられる生薬抽出物としては、生薬を溶媒、
例えば、熱水やメタノール、エタノール等の低級アルコ
ールあるいは含水低級アルコールあるいはプロピレング
リコール、1−3ブチレングリコール等の多価アルコー
ルあるいは含水多価アルコール等の含水アルコール等で
抽出して得られる抽出エキスや、その抽出エキスを濃縮
乾燥して得られる抽出物等が挙げられる。本発明におけ
る生薬抽出物の配合量は、養毛料金量中、乾燥物として
o、oos〜10重量%、好ましくは0.01〜5重量
%である。o、oos重量%未満であると、本発明でい
う効果が十分に発揮されず、好ましくない。
As the crude drug extract used in the present invention, the crude drug is used as a solvent,
For example, extracts obtained by extraction with hot water, lower alcohols such as methanol, ethanol, hydrous lower alcohols, polyhydric alcohols such as propylene glycol, 1-3 butylene glycol, or hydrous alcohols such as hydrous polyhydric alcohols, Examples include extracts obtained by concentrating and drying the extracted extract. The blending amount of the herbal medicine extract in the present invention is from o,oos to 10% by weight, preferably from 0.01 to 5% by weight, as a dry matter, in the hair nourishment amount. If it is less than o, oos weight%, the effect of the present invention will not be sufficiently exhibited, which is not preferable.

請求項1記載のアニオン性界面活性剤としては、カルボ
ン酸基、スルホン酸基、硫酸エステル基、リン酸エステ
ル基を分子内に一種または二種以上有するアニオン性界
面活性剤が挙げられる。カルボン酸基を有するものとし
ては脂肪酸セッケン、エーテルカルボン酸およびその塩
、アミノ酸と脂肪酸の縮合物等のカルボン酸塩等を、又
、スルホン酸塩を有するものとしては、アルキルスルホ
ン酸塩、スルホコハク酸、エステルスルホン酸塩、アル
キルアリル及びアルキルナフタレンスルホン酸塩、N−
アシルスルホン酸塩、ホルマリン縮合系スルホン酸塩等
を、硫酸エステル基を有するものとしては、硫酸化油、
エステル硫酸塩、アルキル硫酸塩、エーテル硫酸塩、ア
ルキルアリルエーテル硫酸塩、アミド硫酸塩等を、リン
酸エステル基を有するものとしては、アルキルリン酸塩
、アミドリン酸塩、エーテルリン酸塩、アルキルアリル
エーテルリン酸塩等を挙げることができる。これらの中
から一種または二種以上が任意に選択される。
The anionic surfactant according to claim 1 includes anionic surfactants having one or more types of carboxylic acid group, sulfonic acid group, sulfuric acid ester group, and phosphoric acid ester group in the molecule. Those with carboxylic acid groups include fatty acid soaps, ether carboxylic acids and their salts, carboxylates such as condensates of amino acids and fatty acids, and those with sulfonates include alkyl sulfonates and sulfosuccinic acids. , ester sulfonates, alkylaryl and alkylnaphthalene sulfonates, N-
Acyl sulfonates, formalin condensation sulfonates, etc. have sulfate ester groups, such as sulfated oils,
Ester sulfates, alkyl sulfates, ether sulfates, alkyl allyl ether sulfates, amide sulfates, etc., those having a phosphoric acid ester group include alkyl phosphates, amide phosphates, ether phosphates, alkylaryl sulfates, etc. Ether phosphates and the like can be mentioned. One or more types are arbitrarily selected from these.

請求項1記載のアニオン性界面活性剤以外で分子内に窒
素原子を有する界面活性剤としては、窒素原子を分子内
に有する両性界面活性剤、半極性界面活性剤、非イオン
性界面活性剤、カチオン性界面活性剤等を挙げることが
できる。両性界面活性剤としては、N、N−ジメチル−
トラウリル−N−カルボキシメチルアンモニウムベタイ
ン、N、N−ジメチル−N−オレイル−N−カルボキシ
メチルアンモニウムベタイン等のカルボキシベタイン、
2−ラウリルート力ルボキシエチル−8−ヒドロキシエ
チルイミダゾリニウムベタイン、2−ラウリル−H−力
シボキシメチル−N−ヒドロキシエチルイミダゾリニウ
ムベタイン等のイミダシリン誘導体、トヤシアルキルー
β−アミノプロピオン酸ソーダ塩、N−ヤシアルキル−
β−イミノジプロピオン酸−ジ−ソーダ塩等のアミノカ
ルボン酸塩、スルホベタイン、アミノベタイン等が挙げ
られる。半極性界面活性剤としては、ジメチルラウリル
アミンオキシド、ビス−(2−とドロキシエチル)ラウ
リルアミンオキシド等が挙げられる。非イオン性界面活
性剤としては、脂肪酸アルカノールアミド、ポリオキシ
エチレン脂肪酸アミド、アルカノールアミンのエステル
、ポリオキシエチレンアルキルアミン等が挙げられる。
Examples of surfactants having a nitrogen atom in the molecule other than the anionic surfactant according to claim 1 include amphoteric surfactants having a nitrogen atom in the molecule, semipolar surfactants, nonionic surfactants, Examples include cationic surfactants. As the amphoteric surfactant, N,N-dimethyl-
carboxybetaine such as trauryl-N-carboxymethylammonium betaine, N,N-dimethyl-N-oleyl-N-carboxymethylammonium betaine,
Imidacillin derivatives such as 2-lauryl-hydroxyethyl-8-hydroxyethylimidazolinium betaine, 2-lauryl-H-hydroxymethyl-N-hydroxyethylimidazolinium betaine, cocoalkyl-β-aminopropionic acid sodium salt, N-cocoalkyl-
Examples include aminocarboxylic acid salts such as β-iminodipropionic acid di-soda salt, sulfobetaine, aminobetaine, and the like. Examples of the semipolar surfactant include dimethyl lauryl amine oxide, bis-(2-and droxyethyl) lauryl amine oxide, and the like. Examples of the nonionic surfactant include fatty acid alkanolamide, polyoxyethylene fatty acid amide, alkanolamine ester, polyoxyethylene alkylamine, and the like.

カチオン性界面活性剤としては、脂肪酸アミン塩、アル
キル四級アンモニウム塩、芳香族四級アンモニウム塩、
ピリジウム塩、イミダゾリウム塩等が挙げられる。これ
らの中から一種又は二種以上が任意に選択きれる。
Examples of cationic surfactants include fatty acid amine salts, alkyl quaternary ammonium salts, aromatic quaternary ammonium salts,
Examples include pyridium salts and imidazolium salts. One or more types can be arbitrarily selected from these.

請求項2記載の両性界面活性剤としては、N、N−ジメ
チル−N−ラウリル−N−カルボキシメチルアンモニウ
ムベタイン、N、N−ジメチル−H−オレイル−N−力
ルボキシメチルアンモニウムベタイン等のカルボキシベ
タイン、2−ラウリル−N−カルボキシエチル−N−ヒ
ドロキシエチルイミダゾリニウムベタイン、2−ラウリ
ル−N−カルボキシメチル−N−ヒドロキシエチルイミ
ダゾリニウムベタイン等のイミダシリン誘導体、トヤシ
アルキルーβ−アミノプロピオン酸ソーダ塩、トヤシア
ルキルーβ−イミノジプロピオン酸−ジ−ソーダ塩等の
アミノカルボン酸塩、スルホベタイン、アミノベタイン
等が挙げられる。
The amphoteric surfactant according to claim 2 is a carboxylic surfactant such as N,N-dimethyl-N-lauryl-N-carboxymethylammonium betaine, N,N-dimethyl-H-oleyl-N-carboxymethylammonium betaine, etc. Imidacillin derivatives such as betaine, 2-lauryl-N-carboxyethyl-N-hydroxyethylimidazolinium betaine, 2-lauryl-N-carboxymethyl-N-hydroxyethylimidazolinium betaine, toyacyalkyl-β-aminopropionic acid sodium salt , aminocarboxylic acid salts such as toyashalkyl-β-iminodipropionic acid di-soda salt, sulfobetaine, aminobetaine, and the like.

請求項2記載の半極性界面活性剤としては、ジメチルラ
ウリルアミンオキシド、ビス−(2−ヒドロキシエチル
)ラウリルアミンオキシド等が挙げられる。
Examples of the semipolar surfactant according to claim 2 include dimethyl lauryl amine oxide, bis-(2-hydroxyethyl) lauryl amine oxide, and the like.

請求項2記載の非イオン性界面活性剤としては、脂肪酸
アルカノールアミド、ポリオキシエチレン脂肪酸アミド
、アルカノールアミンのエステル、ポリオキシエチレン
アルキルアミン等が挙げられる。
Examples of the nonionic surfactant according to claim 2 include fatty acid alkanolamide, polyoxyethylene fatty acid amide, alkanolamine ester, polyoxyethylene alkylamine, and the like.

請求項3記載のアミンオキシドとしては、下記一般式(
A)〜(C)のものが挙げられる。
The amine oxide according to claim 3 has the following general formula (
Examples are A) to (C).

R1 R2−N−+O(A) (式中R1、R2およびR3は炭素原子数1がら24の
直鎖または分枝の飽和又は不飽和の炭化水素基を表わし
、R1、R2、R3のうち少なくとも1個は炭素原子数
8以上の直鎖または分枝の飽和又は不飽和の炭化水素基
を表わす。) 一般式(A)で表わされるアミンオキシドの具体例とし
ては、ジメチルラウリルアミンオキシド、ジメチルミリ
スチルアミンオキシド、ジメチルセチルアミンオキシド
、ジメチルステアリルアミンオキシド、ジメチルセチル
アミンオキシド、ジメチルベヘニルアミンオキシド、メ
チルジラウリルアミンオキシドなどが挙げられる。
R1 R2-N-+O(A) (In the formula, R1, R2 and R3 represent a straight chain or branched saturated or unsaturated hydrocarbon group having 1 to 24 carbon atoms, and at least (One represents a straight chain or branched saturated or unsaturated hydrocarbon group having 8 or more carbon atoms.) Specific examples of the amine oxide represented by the general formula (A) include dimethyl lauryl amine oxide, dimethyl myristyl Examples include amine oxide, dimethylcetylamine oxide, dimethylstearylamine oxide, dimethylcetylamine oxide, dimethylbehenylamine oxide, and methyldilaurylamine oxide.

Cf(2CH20H R4N→0              (B)C82
CR20H (式中R4は炭素原子数8から24の直鎖または分枝の
飽和又は不飽和の炭化水素基を表わす。) H3 R5−(OCH2CH2)n   N→0    (C
)H3 (式中R5は炭素原子数8から24の直鎖または分枝の
飽和又は不飽和の炭化水素基を表わし、nは1から5の
整数を表わす。) 本発明においては、これらアミンオキシドの一種または
二種以上が任意に選択され、用いられる。
Cf(2CH20H R4N→0 (B)C82
CR20H (In the formula, R4 represents a straight chain or branched saturated or unsaturated hydrocarbon group having 8 to 24 carbon atoms.) H3 R5-(OCH2CH2)n N→0 (C
)H3 (In the formula, R5 represents a straight chain or branched saturated or unsaturated hydrocarbon group having 8 to 24 carbon atoms, and n represents an integer of 1 to 5.) In the present invention, these amine oxides One or more of these are arbitrarily selected and used.

請求項1記載のアニオン性界面活性剤と、アニオン性界
面活性剤以外で分子内に窒素原子を有する界面活性剤の
合計配合量は、養毛料金量中0.001〜10重量%が
好ましく、さらに好ましくは0.01〜5重量%である
。また、アニオン性界面活性剤と、アニオン性界面活性
剤以外で分子内に窒素原子を有する界面活性剤との割合
は、分子比で20:1〜1:20が好ましく、ざらに好
ましくは10:1〜1:10である。
The total amount of the anionic surfactant according to claim 1 and a surfactant other than the anionic surfactant having a nitrogen atom in the molecule is preferably 0.001 to 10% by weight based on the amount of hair nourishing fee. More preferably, it is 0.01 to 5% by weight. Further, the ratio of the anionic surfactant to the surfactant other than the anionic surfactant having a nitrogen atom in the molecule is preferably 20:1 to 1:20 in molecular ratio, more preferably 10: The ratio is 1 to 1:10.

請求項2記載の両性界面活性剤と半極性界面活性剤の一
種または二種以上と、分子内に窒素原子を有する非イオ
ン性界面活性剤の一種漬たは二種以上の合計配合量は、
養毛料全量中0.001〜10重量%が好ましく、ざら
に好まし、くは0.01〜5重量%である。また、両性
界面活性剤と半極性界面活性剤の一種または二種以上と
、分子内に窒素原子を有する非イオン性界面活性剤の一
種または二種以上との割合は、分子比で20=1〜1:
20が好ましく、さらに好ましくは10:1〜1:10
である。
The total blending amount of one or more of the amphoteric surfactant and semipolar surfactant according to claim 2, and one or more of the nonionic surfactant having a nitrogen atom in the molecule is:
It is preferably 0.001 to 10% by weight, most preferably 0.01 to 5% by weight, based on the total amount of the hair nourishing agent. In addition, the ratio of one or more amphoteric surfactants and semipolar surfactants to one or more nonionic surfactants having a nitrogen atom in the molecule is 20 = 1. ~1:
20 is preferable, more preferably 10:1 to 1:10
It is.

請求項3記載のアミンオキシドの配合量は、養毛料全量
中の0.0001〜20重量%が好ましい。配合量が0
.0001重量%未満では十分な養毛効果が得られず、
20重量%を越えると製剤上または皮膚刺激の上からも
好ましくない。
The amount of the amine oxide according to claim 3 is preferably 0.0001 to 20% by weight based on the total amount of the hair nourishment. Blend amount is 0
.. If it is less than 0001% by weight, sufficient hair nourishing effect cannot be obtained,
If it exceeds 20% by weight, it is undesirable from the standpoint of formulation and skin irritation.

本発明に係る養毛料には、上記必須成分のほかに、通常
養毛料に用いられる汎用成分、例えばビタミンB6、ビ
タミンE及びその誘導体、ビオチン等のビタミン類、パ
ントテン酸及びその誘導体、グリチルレチン酸及びその
誘導体、ニコチン酸ベンジル等のニコチン酸エステル類
、サイクロスポリン類、塩化カルプロニウム、セファラ
ンチン、オキセンドロン、ジアゾキシド、ミノキシジル
、エチニルエストラジオールなどの発毛剤又は発毛助剤
、ヒノキチオール、ヘキサクロロフェン、フェノール、
ベンザルコニウムクロリド、セチルピリジニウムクロリ
ド、ウンデシレン酸、トリクロロカルバニリド及びピチ
オノールなどの抗菌剤、メントールなどの清涼剤、サリ
チル酸、亜鉛及びその誘導体、乳酸及びそのアルキルエ
ステルなどの薬剤、クエン酸等の有機酸類、アルギニン
等のアミノ酸類、オリーブ油、スクワラン、流動パラフ
ィン、イソプロピルミリステート、高級脂肪酸、高級ア
ルコールなどの油分、グリセリン、プロピレングリコー
ル等の多価アルコール、香料、酸化防止剤、紫外線吸収
剤、色素、エタノール、ベンジルアルコール、イソプロ
ピルアルコール等のアルコール類、水、保湿剤、増粘剤
などが本発明の効果を損なわない範囲で適宜配合するこ
とができる。
In addition to the above-mentioned essential ingredients, the hair nourishment according to the present invention includes general-purpose ingredients normally used in hair nourishing agents, such as vitamin B6, vitamin E and its derivatives, vitamins such as biotin, pantothenic acid and its derivatives, glycyrrhetinic acid, and Derivatives thereof, nicotinic acid esters such as benzyl nicotinate, cyclosporins, carpronium chloride, cephalanthine, oxendrone, diazoxide, minoxidil, hair growth aids such as ethinyl estradiol, hinokitiol, hexachlorophene, phenol,
Antibacterial agents such as benzalkonium chloride, cetylpyridinium chloride, undecylenic acid, trichlorocarbanilide and pithionol, cooling agents such as menthol, drugs such as salicylic acid, zinc and its derivatives, lactic acid and its alkyl esters, and organics such as citric acid. Acids, amino acids such as arginine, oils such as olive oil, squalane, liquid paraffin, isopropyl myristate, higher fatty acids, higher alcohols, polyhydric alcohols such as glycerin and propylene glycol, fragrances, antioxidants, ultraviolet absorbers, pigments, Alcohols such as ethanol, benzyl alcohol, and isopropyl alcohol, water, humectants, thickeners, and the like can be appropriately blended within the range that does not impair the effects of the present invention.

本発明の養毛料は、液状、乳液、軟膏、クリーム、ゲル
、エアゾールなど外皮に適用できる剤型のものであれば
いずれでもよく、トニック、コンディショナー スカル
プトリートメント、シャンプー、リンスなどの形態で用
いられる。
The hair nourishing agent of the present invention may be in any form as long as it can be applied to the outer skin, such as liquid, emulsion, ointment, cream, gel, aerosol, etc., and is used in the form of tonic, conditioner, scalp treatment, shampoo, rinse, etc.

[実施例1 次に、実施例により本発明について詳細に説明する。本
発明はこれらにより限定されるものではない。配合量は
重量%である。
[Example 1] Next, the present invention will be explained in detail with reference to Examples. The present invention is not limited to these. The blending amount is in weight%.

i且効−果JΣ測−Z法(マウスでの育毛効果測定)雄
のC3Hマウス(生後60日)を用い、小川らの方法[
(Normal and Abnormal Epid
ermal Dif−ferentiation ) 
M、5eiji and 1.A、Bernstein
 m集束大出版会]に従い実験を行なった。すなわち、
マウスの背部上を約2X4cmの大きさに剃り、翌日よ
り1日1回ずつ連日サンプル塗布を行ない、毛再生が始
まった部分の面積比の変化を求め、毛再生の早さの比較
を行なった。サンプルは各生薬抽出液の乾燥物を75%
エタノールに攪拌溶解し、これに界面活性剤を添加、溶
解しサンプルとした。試験には対照として75%エタノ
ールを用いた。各試料ともマウス10匹ずつを用い、そ
の変化率の平均値を求めた。20日後毛再生面積の結果
を百分率にて表−1に示した。
I and effect JΣ measurement-Z method (measuring hair growth effect in mice) Using male C3H mice (60 days old), Ogawa et al.'s method [
(Normal and Abnormal Epid
ermal Dif-ferentiation)
M, 5eiji and 1. A.Bernstein
The experiment was carried out in accordance with M Shokushu Dai Shuppankai]. That is,
The top of the mouse's back was shaved to a size of approximately 2 x 4 cm, and samples were applied once a day starting from the next day. Changes in the area ratio of the area where hair regeneration had started were determined and the speed of hair regeneration was compared. . The sample is 75% dry matter of each crude drug extract.
The sample was dissolved in ethanol with stirring, and a surfactant was added and dissolved therein to prepare a sample. 75% ethanol was used as a control in the test. Ten mice were used for each sample, and the average value of the rate of change was determined. The results of the hair regeneration area after 20 days are shown in Table 1 as a percentage.

比較例 1 (1)75%エタノール 比較例 2 (1)センブリの 50%エタノール抽出物(乾燥物) (2)75%エタノール 0.2 残余 比較例 3 (1)トウキの 70%エタノール抽出物(乾燥物) (2)75%エタノール 0.2 残余 比較例 4 (1)クラン50%エタノール抽出物(乾燥物)0.2
(2)75%エタノール 残余 (2)75%エタノール 残余 比較例 5 (1)チクセツニンジンの 50%エタノール抽出物(乾燥物) (2)75%エタノール 0.2 残余 実施例 1 (1)アオギリの 50%エタノール抽出物(乾燥物) (2)75%エタノール 0.2 残余 実施例 2 (1)ハクヨウの 70%エタノール抽出物(乾燥物) (2)75%エタノール 0.2 残余 実施例 3 (1)モクセイの 50%エタノール抽出物(乾燥物) 0.2 実施例 4 (1)ジメチルラウリルアミンオキシド(2)アオギリ
の 50%エタノール抽出物(乾燥物) (3)75%エタノール 0.1 0.1 残余 実施例 5 (1)ジメチルステアリルアミンオキシド(2)ハクヨ
ウのメタノール抽出物(乾燥物)(3)75%エタノー
ル 0.1 0.1 残余 実施例 6 (1)ジメチルラウリルアミンオキシド(2)モクセイ
の 50%エタノール抽出物(乾燥物) (3)75%エタノール 0.1 0.1 残余 実施例 7 (1)ジメチルステアリルアミンオキシド(2)ホコッ
シの1.3−ブチレン グリコール抽出物(乾燥物) (3)75%エタノール 実施例 8 (1)ドデシルベンゼンスルホネート (2)ラウリルジメチルアミンオキシド(3)ハクコラ
の 70%エタノール抽出物(乾燥物) (4)75%エタノール 実施例 9 (1)ラウリル硫酸ナトリウム (2)ジメチルラウリルアミンオキシド(3)ヨヂシの
エタノール抽出物(乾燥物)(4)75%エタノール 実施例 10 (1)ジメチルステアリルアミンオキシド0.1 0.1 残余 0.05 0.05 0.1 残余 0.04 0.06 0.1 残余 0.075 (2)ラウリル硫酸ナトリウム (3)シラカバの熱水抽出物(乾燥物)(4)75%エ
タノール 実施例 11 (1)ジメチルステアリルアミンオキシ(2)モノナト
リウムラウリル フォスフェート (3)ケイヒの 70%エタノール抽出物(乾燥物) (4)75%エタノール ド 実施例 12 (1)ジメチルステアリルアミンオキシド(2)ラウリ
ルメチルタウリンナトリウム(3)オオクリハランの メタノール抽出物(乾燥物) (4)リョウキョウの熱水抽出物(乾燥物)(5)75
%エタノール 0.025 0.1 残余 0.15 0.05 0.05 残余 0.03 0.02 0.1 0.05 残余 実施例 13 (1)ラウリルアミノ酢酸ベタイン (2)ラウロイルジェタノールアミド (3)ハンゲの 70%エタノール抽出物(乾燥物) (4)フヒョウの メタノール抽出物(乾燥物) (5)テウヂグルミの プロパツール抽出物(乾燥物) (6)75%エタノール 実施例 14 (1)ジメチルラウリルアミンオキシド(2)モノナト
リウム ラウリルフォスフェート (3)グバクの 70%エタノール抽出物(乾燥物) (4)チンどのメタノール抽出物(乾燥物)(5)グカ
ヒの プロパツール抽出物(乾燥物) 0.03 0.02 0.05 0.05 0.05 残余 0.04 0.01 0.05 0.05 0.05 (6)75%エタノール 実施例 15 (1)ジメチルラウリルアミンオキシド(2)ラウリル
メチルタウリンナトリウム(3)ウバイの 70%エタノール抽出物(乾燥物) (4)アンマロクの メタノール抽出物(乾燥物) (5)オオギの プロパツール抽出物(乾燥物) (6)75%エタノール 実施例 16 (1)ラウリルアミノ酢酸ベタイン (2)ラウロイルジェタノールアミド (3)イラクサの 70%エタノール抽出物(乾燥物) (4)ゲドクシの メタノール抽出物(乾燥物) 残余 0.03 0.02 0.05 0.05 0.05 残余 0.03 0.02 0.05 0.05 (5)バクセンの プロパツール抽出物(乾燥物) (6)75%エタノール 実施例 17 (1)ジメチルオレイルアミンオキシド(2)ラウロイ
ルジェタノールアミド (3)マクワウリの 70%エタノール抽出物(乾燥物) (4)ハクショウの メタノール抽出物(乾燥物) (5)ヒャクゴウの プロパツール抽出物(乾燥物) (6)75%エタノール 実施例 18 (1)ジメチルラウリルアミンオキシド(2)ラウリル
硫酸ナトリウム (3)サンキュウの 70%エタノール抽出物(乾燥物) 0.05 残余 (4)サッシヨウの メタノール抽出物(乾燥物) (5)ショウブの プロパツール抽出物(乾燥物) (6)75%エタノール 0.05 0.05 残余 0.03 0、O2 0,05 0,05 0,05 残余 0.05 実施例 19 (1)ジメチルオレイルアミンオキシド(2)モノナト
リウム ラウリルグルタメート (3)トウヨウの 70%エタノール抽出物(乾燥物) (4)セイコウの メタノール抽出物(乾燥物) (5)コノテガシワの プロパツール抽出物(乾燥物) (6)75%エタノール 0.06 0.01 0.04 0.04 0.05 残余 0.01 0.04 実施例20   ヘアートニック 以下に示す組成のトニックを調製して実使用にてフケ、
発毛、脱毛等の症状に対する効果を検討した。
Comparative example 1 (1) 75% ethanol Comparative example 2 (1) 50% ethanol extract (dry product) of Aspergillus sp. (dry product) (2) 75% ethanol 0.2 Residue Comparative Example 4 (1) Crane 50% ethanol extract (dry product) 0.2
(2) 75% ethanol residual (2) 75% ethanol residual Comparative Example 5 (1) 50% ethanol extract of Panax ginseng (dried product) (2) 75% ethanol 0.2 Residue Example 1 (1) Aogiri (2) 75% ethanol 0.2 Residue Example 2 (1) 70% ethanol extract (dry product) of Prunus japonicus (dry product) (2) 75% ethanol 0.2 Residue Example 3 (1) 50% ethanol extract of Osmanthus (dry product) 0.2 Example 4 (1) Dimethyl laurylamine oxide (2) 50% ethanol extract of Ossiflora (dry product) (3) 75% ethanol 0.1 0.1 Remaining Example 5 (1) Dimethylstearylamine oxide (2) Methanol extract of Hakuyo (dry product) (3) 75% ethanol 0.1 0.1 Remaining Example 6 (1) Dimethyllaurylamine oxide ( 2) 50% ethanol extract (dry product) of Osmanthus japonica (3) 75% ethanol 0.1 0.1 Remaining Example 7 (1) Dimethylstearylamine oxide (2) 1,3-butylene glycol extract of Osmanthus japonica ( Dry product) (3) 75% ethanol Example 8 (1) Dodecylbenzene sulfonate (2) Lauryl dimethylamine oxide (3) 70% ethanol extract of Hakukola (dry product) (4) 75% ethanol Example 9 (1 ) Sodium lauryl sulfate (2) Dimethyllaurylamine oxide (3) Ethanol extract of Yojishi (dry product) (4) 75% ethanol Example 10 (1) Dimethylstearylamine oxide 0.1 0.1 Remaining 0.05 0 .05 0.1 Remaining 0.04 0.06 0.1 Remaining 0.075 (2) Sodium lauryl sulfate (3) Birch birch hot water extract (dried product) (4) 75% ethanol Example 11 (1) Dimethylstearylamine oxy (2) Monosodium lauryl phosphate (3) 70% ethanol extract of cinnamon bark (dry product) (4) 75% ethanold Example 12 (1) Dimethylstearylamine oxide (2) Sodium lauryl methyl taurate (3) Methanol extract of Ookuriharan (dry product) (4) Hot water extract of Ryokyo (dry product) (5) 75
% ethanol 0.025 0.1 Residue 0.15 0.05 0.05 Residue 0.03 0.02 0.1 0.05 Residue Example 13 (1) Lauryl aminoacetic acid betaine (2) Lauroyl jetanolamide ( 3) 70% ethanol extract (dry product) of Hangae (4) Methanol extract (dry product) of Fuhyeopsis (5) Proper tool extract (dry product) of Teujigurumi (6) 75% ethanol Example 14 (1) Dimethyl laurylamine oxide (2) Monosodium lauryl phosphate (3) 70% ethanolic extract of Gubaku (dry product) (4) Methanol extract of Chindo (dry product) (5) Propatur extract of Gukahi (dry product) ) 0.03 0.02 0.05 0.05 0.05 Remaining 0.04 0.01 0.05 0.05 0.05 (6) 75% ethanol Example 15 (1) Dimethyllaurylamine oxide (2 ) Sodium lauryl methyl taurate (3) 70% ethanol extract of Ubai (dry product) (4) Methanol extract of Ammarok (dry product) (5) Propateur extract of Aspergillus orientalis (dry product) (6) 75% ethanol Example 16 (1) Betaine lauryl aminoacetate (2) Lauroylgetanolamide (3) 70% ethanolic extract of stinging nettle (dry product) (4) Methanol extract of Japanese nettle (dry product) Remaining 0.03 0.02 0.05 0.05 0.05 Remaining 0.03 0.02 0.05 0.05 (5) Baxen propatool extract (dried product) (6) 75% ethanol Example 17 (1) Dimethyloleylamine oxide (2) Lauroylgetanolamide (3) 70% ethanolic extract of Oriental melon (dried) (4) Methanol extract of Oriental chinensis (dried) (5) Propatur extract of Oriental chinensis (dried) (6) 75 % Ethanol Example 18 (1) Dimethyllaurylamine oxide (2) Sodium lauryl sulfate (3) 70% ethanol extract of Sankyu (dry product) 0.05 Remaining amount (4) Methanol extract of Sasshiyou (dry product) (5 ) Calamus propator extract (dried) (6) 75% ethanol 0.05 0.05 Remaining 0.03 0, O2 0.05 0.05 0.05 Remaining 0.05 Example 19 (1) Dimethyl Oleylamine oxide (2) Monosodium lauryl glutamate (3) 70% ethanolic extract (dry product) of Porphyra sativa (dry product) (4) Methanol extract (dry product) of Seiko prunus (5) Propatur extract (dry product) (6) ) 75% ethanol 0.06 0.01 0.04 0.04 0.05 Remaining 0.01 0.04 Example 20 Hair tonic A tonic with the composition shown below was prepared and used to treat dandruff,
The effects on symptoms such as hair growth and hair loss were investigated.

フケ、発毛、脱毛等の症状を呈する20名の男性(年齢
24〜60才)に1日1〜2回゛、1〜5 mLずつ4
力月にわたって塗布し、表−2の結果を得た。
Administer 1 to 5 mL 1 to 2 times a day to 20 men (age 24 to 60) with symptoms such as dandruff, hair growth, and hair loss.
The coating was applied for several months, and the results shown in Table 2 were obtained.

フケ、発毛及−び脱毛等の症状に優れていた。It was excellent in treating symptoms such as dandruff, hair growth, and hair loss.

表−1から明らかなように各実施例において毛の再生に
対する効果が認められた。
As is clear from Table 1, the effect on hair regeneration was observed in each Example.

(1)オウロの 70%エタノール抽出物(乾燥物) (2)カッコンの 90%エタノール抽出物(乾燥物) (3)ゴミシのメタノール抽出物(乾燥物)(4)ジメ
チルラウリルアミンオキシド(5)ラウリル硫酸ナトリ
ウム (6)プロピレングリコール (7)ヒアルロン酸ナトリウム (8)75%エタノール 0.05 1.0 0.5 0.3 0.05 5.0 0.01 残余 前記の表−2においては下記基準により効果判定を行っ
た。
(1) 70% ethanol extract of Ouro (dry product) (2) 90% ethanol extract of Kakkon (dry product) (3) Methanol extract of Gomishi (dry product) (4) Dimethyllaurylamine oxide (5) Sodium lauryl sulfate (6) Propylene glycol (7) Sodium hyaluronate (8) 75% ethanol 0.05 1.0 0.5 0.3 0.05 5.0 0.01 The remainder is as follows in Table 2 above. Effects were evaluated based on criteria.

1、フケ防止効果テスト 「無効」とは治療にも拘らず何らの改善もみられないも
の。
1. Dandruff prevention effect test ``Ineffective'' means that no improvement is seen despite treatment.

「有効」とはフケの発生が減少したもの。"Effective" means that the occurrence of dandruff has been reduced.

「著効」とはフケの発生が止まったもの。"Remarkable effect" means that dandruff has stopped occurring.

2、発毛効果テスト 「無効」とは治療にも拘らず何らの改善もみられないも
の。
2. Hair growth effect test ``Ineffective'' means that no improvement is seen despite treatment.

「有効」とは脱毛部の2/3以上に毛の新生が認やられ
るもの。
"Effective" means that new hair growth is observed in 2/3 or more of the hair loss area.

「著効」とは脱毛部に毛が生えそろったもの。``Remarkable effect'' means that hair has grown in the hair removal area.

3、脱毛効果テスト 「無効」とは治療にも拘らず何らの改善もみられないも
の。
3. Hair removal effect test ``Ineffective'' means that no improvement is seen despite treatment.

「有効」とは脱毛の進行が減少したもの。"Effective" means that the progression of hair loss has been reduced.

「著効」とは脱毛が止まったもの。“Remarkable response” means that hair loss has stopped.

実施例21  ヘアートニック (1)コブシの メタノール抽出物(乾燥物) (2)コノテガシワの 80%エタノール抽出物(乾燥物) 0.05 0.05 (3)コソウの1.3−ブチレン グリコール抽出物(乾燥物) (4)ショウバクの 90%エタノール抽出物(乾燥物) (5)ドクヨウイッシカの 熱水抽出物(乾燥物) (6)ニレの 70%エタノール抽出物(乾燥物) (7)ポリオキシエチレン(8モル) オレイルアルコールエーテル (8)1.3−ブチレングリコール (9)60%エタノール 実施例22   シャンプー (1)ココイルメチルタウリンナトリウム(2)ラウリ
ルジメチル アミノ酢酸ベタイン (3)ラウリン酸ジェタノールアミド (4)エチレングリコール脂肪酸エステル(5)プロピ
レングリコール 0.05 0.05 0.05 0.05 0.05 0.05 残余 (6)リュウヨウの 70%エタノール抽出物(乾燥物) (7)レンの 50%エタノール抽出物(乾燥物) (8)ハンミョウの メタノール抽出物(乾燥物) (9)アオギリのプロピレン グリフール抽出物(乾燥物) (10)エデト酸2ナトリウム (11)香料 (12)精製水 1.0 1.0 1.0 0.2 0.1 適量 残部 6.0 8.0 4.0 1.5 2.0 実施例23   リンス (1)ステアリルトリメチル アンモニウムクロリド (2)セチルアルコール (3)シリコン油 (4)ポリオキシエチレン(10モル)オレイルアルコ
ールエーテル (5)グリセリン 1.5 2.0 3.0 1.0 5.0 (6)ウバイのメタノール抽出物(乾燥物)(7)バク
センの メタノール抽出物(乾燥物) (8)ホコッシの熱水抽出物(乾燥物)(9)フヒョウ
の 70%エタノール抽出物(乾燥物) (10)精製水 (11)防腐剤 (12)紫外線吸収剤 0.5 0.5 1.0 1.0 84.0 適量 適量 実施例24   ヘアクリーム (1)ミツロウ (2)ワセリン (3)流動パラフィン (4)ポリオキシエチレン(5モル) ステアリン酸エステル (5)ポリオキシエチレン(6モル) オレイルアルコールエーテル (6)ゴカヒの 90%プロパツール抽出物(乾燥物) 3.0 15.0 42.0 3.0 1.0 0.3 (7)リョウキョウの 50%メタノール抽出物(乾燥物) (8)チンどの 70%エタノール抽出物(乾燥物) (9)精製水 (10)香料 (11)防腐剤 0.2 0.4 35.1 適量 適量 実施例21〜24は、いずれも養毛効果に優れていた。
Example 21 Hair tonic (1) Methanol extract of Kobushu (dry product) (2) 80% ethanol extract of Kobushu (dry product) 0.05 0.05 (3) 1.3-butylene glycol extract of Kosou (Dried product) (4) 90% ethanol extract of P. elegans (dry product) (5) Hot water extract of P. elegans (dry product) (6) 70% ethanol extract of Elm (dry product) (7) Polyoxy Ethylene (8 moles) Oleyl alcohol ether (8) 1,3-butylene glycol (9) 60% ethanol Example 22 Shampoo (1) Sodium cocoyl methyl taurate (2) Betaine lauryldimethylaminoacetate (3) Lauric acid jetanolamide (4) Ethylene glycol fatty acid ester (5) Propylene glycol 0.05 0.05 0.05 0.05 0.05 0.05 Residue (6) 70% ethanol extract (dry product) of Ryuyou (7) Ren 50% ethanol extract (dry product) (8) Methanol extract of Hanmyo (dry product) (9) Propylene glyfur extract of Aspergillus perilla (dry product) (10) Disodium edetate (11) Flavor (12) Purification Water 1.0 1.0 1.0 0.2 0.1 Appropriate amount remaining 6.0 8.0 4.0 1.5 2.0 Example 23 Rinse (1) Stearyltrimethylammonium chloride (2) Cetyl alcohol ( 3) Silicone oil (4) Polyoxyethylene (10 mol) Oleyl alcohol ether (5) Glycerin 1.5 2.0 3.0 1.0 5.0 (6) Methanol extract of Ubay (dried) (7 ) Methanol extract of Baxen (dried product) (8) Hot water extract of Hokossi (dry product) (9) 70% ethanol extract of Fuhyo (dry product) (10) Purified water (11) Preservative (12) UV absorber 0.5 0.5 1.0 1.0 84.0 Appropriate amount Appropriate amount Example 24 Hair cream (1) Beeswax (2) Vaseline (3) Liquid paraffin (4) Polyoxyethylene (5 moles) Stearic acid Ester (5) Polyoxyethylene (6 moles) Oleyl alcohol ether (6) 90% propatool extract of Gocahi (dried) 3.0 15.0 42.0 3.0 1.0 0.3 (7) 50% methanol extract (dry product) of chinensis (8) 70% ethanol extract (dry product) of chinensis (9) Purified water (10) Flavor (11) Preservative 0.2 0.4 35.1 Appropriate amount Appropriate amount Examples 21 to 24 were all excellent in hair-nourishing effects.

[発明の効果] 本発明の養毛料は、特定の生薬抽出物または、特定の生
薬抽出物と特定の界面活性剤とを含有することにより、
従来の養毛料よりも著しく優れた各種の性質(例えば、
発毛、育毛、脱毛防止効果等)を示す。
[Effect of the invention] The hair nourishment of the present invention contains a specific crude drug extract or a specific crude drug extract and a specific surfactant, thereby achieving the following effects:
Various properties that are significantly superior to conventional hair nourishing agents (e.g.
hair growth, hair growth, hair loss prevention effects, etc.).

特許出願人  株式会社 資生堂Patent applicant: Shiseido Co., Ltd.

Claims (4)

【特許請求の範囲】[Claims] (1)アオギリ、アンマロク、ウバイ、イラクサ、オオ
クリハラン、オオギ、オウロ、カッコン、グバク、ケイ
ヒ、ゲドクシ、ゴカヒ、コソウ、ゴミシ、コブシ、コノ
テガシワ、サンキュウ、チンピ、テウチグルミ、セイコ
ウ、サッシヨウ、ドクヨウイッシカ、ショウブ、ショウ
バク、シラカバ、ニレ、リョウキョウ、リュウヨウ、ヨ
チシ、ホコツシ、トウヨウ、ヒャクゴウ、レン、モクセ
イ、ハンミョウ、フヒョウ、マクワウリ、ハクコウ、ハ
ンゲ、バクセン、ハクショウ、ハクヨウからなる群から
選ばれる生薬抽出物の一種又は二種以上を含有してなる
養毛料。
(1) Aogiri, Anmaroku, Ubai, Nettle, Ookuriharan, Oogi, Ouro, Kakkon, Gubaku, Keihi, Gedokushi, Gokahi, Kosou, Gomishi, Kobushi, Konotegashiwa, Sankyu, Chimpi, Teuchigurumi, Seiko, Sasshiyou, Dokuyouishika, Calamus, Shobu one or two crude drug extracts selected from the group consisting of , birch, elm, chinensis, chinensis, yochishi, hokotsushi, trumpet, hyakugo, wren, osmanthus, chinensis, chinensis, chinensis, chinensis, hange, baxcens, chinensis, and chinensis. A hair nourishment containing seeds or more.
(2)アオギリ、アンマロク、ウバイ、イラクサ、オオ
クリハラン、オオギ、オウロ、カッコン、グバク、ケイ
ヒ、ゲドクシ、ゴカヒ、コソウ、ゴミシ、コブシ、コノ
テガシワ、サンキュウ、チンピ、テウチグルミ、セイコ
ウ、サッシヨウ、ドクヨウイッシカ、ショウブ、ショウ
バク、シラカバ、ニレ、リョウキョウ、リュウヨウ、ヨ
チシ、ホコツシ、トウヨウ、ヒャクゴウ、レン、モクセ
イ、ハンミョウ、フヒョウ、マクワウリ、ハクコウ、ハ
ンゲ、バクセン、ハクショウ、ハクヨウからなる群から
選ばれる生薬の抽出物の一種又は二種以上と、アニオン
性界面活性剤の一種又は二種以上と、アニオン界面活性
剤以外で分子内に窒素原子を有する界面活性剤の一種又
は二種以上とを含有することを特徴とする養毛料。
(2) Aogiri, Anmaroku, Ubai, Nettle, Ookuriharan, Oogi, Ouro, Kakkon, Gubaku, Keihi, Gedokushi, Gokahi, Kosou, Gomishi, Kobushi, Konotegashiwa, Sankyu, Chimpi, Teuchigurumi, Seikou, Sasshiyou, Dokuyouishika, Calamus, Shobu , birch, elm, chinensis, ryuyou, yochishi, hokotsushi, toyo, hyakugo, wren, osmanthus, japonica, japonica, japonica, cypress, hange, baxcens, cypress, cypress, or an extract of a herbal medicine selected from the group consisting of A surfactant containing two or more types of surfactants, one or more types of anionic surfactants, and one or more types of surfactants having a nitrogen atom in the molecule other than anionic surfactants. Hair fee.
(3)アオギリ、アンマロク、ウバイ、イラクサ、オオ
クリハラン、オオギ、オウロ、カッコン、グバク、ケイ
ヒ、ゲドクシ、ゴカヒ、コソウ、ゴミシ、コブシ、コノ
テガシワ、サンキュウ、チンピ、テウチグルミ、セイコ
ウ、サッシヨウ、ドクヨウイッシカ、ショウブ、ショウ
バク、シラカバ、ニレ、リョウキョウ、リュウヨウ、ヨ
チシ、ホコツシ、トウヨウ、ヒャクゴウ、レン、モクセ
イ、ハンミョウ、フヒョウ、マクワウリ、ハクコウ、ハ
ンゲ、ハクセン、ハクショウ、ハクヨウからなる群から
選ばれる生薬の抽出物の一種又は二種以上と、両性界面
活性剤と半極性界面活性剤の一種または二種以上と、分
子内に窒素原子を有する非イオン界面活性剤の一種また
は二種以上とを含有することを特徴とする養毛料。
(3) Aogiri, Anmaroku, Ubai, Nettle, Ookuriharan, Oogi, Ouro, Kakkon, Gubaku, Keihi, Gedokushi, Gokahi, Kosou, Gomishi, Kobushi, Konotegashiwa, Sankyu, Chimpi, Teuchigurumi, Seiko, Sasshiyou, Dokuyouishika, Calamus, Shoubaku , birch, elm, chinensis, ryuyou, yochishi, hokotsushi, trumpet, hyakugo, wren, osmanthus, japonica, japonica, japonica, cypress, hange, chinensis, cypress, cypress, or an extract of a herbal medicine selected from the group consisting of one or more types of amphoteric surfactants and semipolar surfactants; and one or more types of nonionic surfactants having a nitrogen atom in the molecule. Hair nourishment.
(4)アオギリ、アンマロク、ウバイ、イラクサ、オオ
クリハラン、オオギ、オウロ、カッコン、グバク、ケイ
ヒ、ゲドクシ、ゴカヒ、コソウ、ゴミシ、コブシ、コノ
テガシワ、サンキュウ、チンピ、テウチグルミ、セイコ
ウ、サンシヨウ、ドクヨウイッシカ、ショウブ、ショウ
バク、シラカバ、ニレ、リョウキョウ、リュウヨウ、ヨ
チシ、ホコツシ、トウヨウ、ヒャクゴウ、レン、モクセ
イ、ハンミョウ、フヒョウ、マクワウリ、ハクコウ、ハ
ンゲ、ハクセン、ハクショウ、ハクヨウからなる群から
選ばれる生薬の抽出物の一種又は二種以上と、アミンオ
キシドとを含有することを特徴とする養毛料。
(4) Aogiri, Anmaroku, Ubai, Nettle, Ookuriharan, Oogi, Ouro, Kakkon, Gubaku, Keihi, Gedokushi, Gokahi, Kosou, Gomishi, Kobushi, Konotegashiwa, Sankyu, Chimpi, Teuchigurumi, Seikou, Sanshiyou, Dokuyouishika, Calamus, Shobu , birch, elm, chinensis, ryuyou, yochishi, hokotsushi, trumpet, hyakugo, wren, osmanthus, japonica, japonica, japonica, cypress, hange, chinensis, cypress, cypress, or an extract of a herbal medicine selected from the group consisting of A hair nourishing agent characterized by containing two or more types and an amine oxide.
JP63198888A 1988-08-11 1988-08-11 Hair restoration Expired - Lifetime JP2814085B2 (en)

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Cited By (19)

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Publication number Priority date Publication date Assignee Title
FR2673840A1 (en) * 1991-03-14 1992-09-18 Lvmh Rech COSMETIC OR PHARMACEUTICAL COMPOSITION, PARTICULARLY DERMATOLOGICAL, CONTAINING OXYACANTHIN, PARTICULARLY FOR STIMULATING THE PUSH OF HAIR OR FOR DELAYING THEIR FALL.
JPH07285833A (en) * 1994-04-15 1995-10-31 Atsushi Nukada Hair tonic agent
WO1998052516A1 (en) * 1997-05-19 1998-11-26 Shiseido Company, Ltd. Scalp care compositions
JPH11240823A (en) * 1998-02-23 1999-09-07 Shiseido Co Ltd Activator for hair papilla
WO1999049839A1 (en) * 1998-04-01 1999-10-07 Hyo Suk Park Topical liquid composition for promoting hair growth and process of manufacturing thereof
JP2000143437A (en) * 1998-11-09 2000-05-23 Ichimaru Pharcos Co Ltd Cosmetic composition containing huhectant vegetable extract
JP2000143488A (en) * 1998-11-16 2000-05-23 Ichimaru Pharcos Co Ltd Cosmetic composition containing humectant plant extract
KR20010000574A (en) * 2000-02-14 2001-01-05 조종원 Hair tonic for hair growth and prevention of depilation
JP2002284648A (en) * 2001-03-27 2002-10-03 National Institute Of Advanced Industrial & Technology Composition for hair restorer
JP2006176424A (en) * 2004-12-21 2006-07-06 Maruzen Pharmaceut Co Ltd TESTOSTERONE 5alpha-REDUCTASE INHIBITOR AND HAIR-GROWING COSMETIC
JP2006219407A (en) * 2005-02-09 2006-08-24 Maruzen Pharmaceut Co Ltd Hair papilla cell proliferation promoter and hair tonic
JP2006232828A (en) * 2005-01-28 2006-09-07 Lion Corp Hair growing tonic, hair growing tonic composition and method of hair growth and restoration
JP2007197387A (en) * 2006-01-27 2007-08-09 Maruzen Pharmaceut Co Ltd TESTOSTERONE 5alpha-REDUCTASE INHIBITOR
JP2009530369A (en) * 2006-03-21 2009-08-27 ヘオング ゲオン チョイ Natural herbal hair growth promoting composition and method for producing the same
DE102008035442A1 (en) 2008-07-26 2010-01-28 Ernst-Moritz-Arndt-Universität Greifswald Preparations from Artemisia Annua, their transformation into micro- and nanoparticles and their use
DE102008035443A1 (en) 2008-07-26 2010-04-29 Ernst-Moritz-Arndt-Universität Greifswald Surfactant-free emulsions with anti-aging effect, their preparation and their use
JP2011084523A (en) * 2009-10-16 2011-04-28 Nicca Chemical Co Ltd Fibroblast growth factor-7 production promoter, and scalp/hair cosmetic, food and drink containing the same
JP2015083571A (en) * 2014-11-21 2015-04-30 日華化学株式会社 Fibroblast growth factor-7 production promoter, and cosmetic for scalp and hair and food and drink containing same
KR20220015016A (en) * 2020-07-30 2022-02-08 지정옥 Pharmaceutical composition for preventing or treating alopecia comprising betula platyphylla extract as an active ingredient

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JPS5484038A (en) * 1977-12-13 1979-07-04 Kunio Nagaoka Hair tonic solution containing extracts of ginger and japanese pepper
JPS5753401A (en) * 1980-09-17 1982-03-30 Pola Chem Ind Inc Hair nourishing agent for promoting hair growth
JPS60178805A (en) * 1984-02-22 1985-09-12 Yakurigaku Chuo Kenkyusho:Kk Hair cosmetic blended with essence extracted from acanthopanax spinosus miq.
JPS643126A (en) * 1987-06-26 1989-01-06 Bitamin Kenkyusho:Kk Androgen acceptor bonding inhibitor
JPS643125A (en) * 1987-06-23 1989-01-06 Ichimaru Pharcos Co Ltd Testosterone 5alpha-reductase inhibitor
JPH01246211A (en) * 1987-12-10 1989-10-02 Pola Chem Ind Inc Hair-restoring or growing accelerator

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JPS5484038A (en) * 1977-12-13 1979-07-04 Kunio Nagaoka Hair tonic solution containing extracts of ginger and japanese pepper
JPS5753401A (en) * 1980-09-17 1982-03-30 Pola Chem Ind Inc Hair nourishing agent for promoting hair growth
JPS60178805A (en) * 1984-02-22 1985-09-12 Yakurigaku Chuo Kenkyusho:Kk Hair cosmetic blended with essence extracted from acanthopanax spinosus miq.
JPS643125A (en) * 1987-06-23 1989-01-06 Ichimaru Pharcos Co Ltd Testosterone 5alpha-reductase inhibitor
JPS643126A (en) * 1987-06-26 1989-01-06 Bitamin Kenkyusho:Kk Androgen acceptor bonding inhibitor
JPH01246211A (en) * 1987-12-10 1989-10-02 Pola Chem Ind Inc Hair-restoring or growing accelerator

Cited By (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2673840A1 (en) * 1991-03-14 1992-09-18 Lvmh Rech COSMETIC OR PHARMACEUTICAL COMPOSITION, PARTICULARLY DERMATOLOGICAL, CONTAINING OXYACANTHIN, PARTICULARLY FOR STIMULATING THE PUSH OF HAIR OR FOR DELAYING THEIR FALL.
US5607693A (en) * 1991-03-14 1997-03-04 Lvmh Recherche Cosmetic or pharmaceutical composition, especially dermatological composition, containing oxyacanthine, intended in particular for stimulating hair growth or retarding hair loss
JPH07285833A (en) * 1994-04-15 1995-10-31 Atsushi Nukada Hair tonic agent
WO1998052516A1 (en) * 1997-05-19 1998-11-26 Shiseido Company, Ltd. Scalp care compositions
JPH11240823A (en) * 1998-02-23 1999-09-07 Shiseido Co Ltd Activator for hair papilla
WO1999049839A1 (en) * 1998-04-01 1999-10-07 Hyo Suk Park Topical liquid composition for promoting hair growth and process of manufacturing thereof
JP2000143437A (en) * 1998-11-09 2000-05-23 Ichimaru Pharcos Co Ltd Cosmetic composition containing huhectant vegetable extract
JP2000143488A (en) * 1998-11-16 2000-05-23 Ichimaru Pharcos Co Ltd Cosmetic composition containing humectant plant extract
KR20010000574A (en) * 2000-02-14 2001-01-05 조종원 Hair tonic for hair growth and prevention of depilation
JP2002284648A (en) * 2001-03-27 2002-10-03 National Institute Of Advanced Industrial & Technology Composition for hair restorer
JP2006176424A (en) * 2004-12-21 2006-07-06 Maruzen Pharmaceut Co Ltd TESTOSTERONE 5alpha-REDUCTASE INHIBITOR AND HAIR-GROWING COSMETIC
JP2006232828A (en) * 2005-01-28 2006-09-07 Lion Corp Hair growing tonic, hair growing tonic composition and method of hair growth and restoration
JP2006219407A (en) * 2005-02-09 2006-08-24 Maruzen Pharmaceut Co Ltd Hair papilla cell proliferation promoter and hair tonic
JP2007197387A (en) * 2006-01-27 2007-08-09 Maruzen Pharmaceut Co Ltd TESTOSTERONE 5alpha-REDUCTASE INHIBITOR
JP2009530369A (en) * 2006-03-21 2009-08-27 ヘオング ゲオン チョイ Natural herbal hair growth promoting composition and method for producing the same
DE102008035442A1 (en) 2008-07-26 2010-01-28 Ernst-Moritz-Arndt-Universität Greifswald Preparations from Artemisia Annua, their transformation into micro- and nanoparticles and their use
DE102008035443A1 (en) 2008-07-26 2010-04-29 Ernst-Moritz-Arndt-Universität Greifswald Surfactant-free emulsions with anti-aging effect, their preparation and their use
JP2011084523A (en) * 2009-10-16 2011-04-28 Nicca Chemical Co Ltd Fibroblast growth factor-7 production promoter, and scalp/hair cosmetic, food and drink containing the same
JP2015083571A (en) * 2014-11-21 2015-04-30 日華化学株式会社 Fibroblast growth factor-7 production promoter, and cosmetic for scalp and hair and food and drink containing same
KR20220015016A (en) * 2020-07-30 2022-02-08 지정옥 Pharmaceutical composition for preventing or treating alopecia comprising betula platyphylla extract as an active ingredient

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