JPS643125A - Testosterone 5alpha-reductase inhibitor - Google Patents

Testosterone 5alpha-reductase inhibitor

Info

Publication number
JPS643125A
JPS643125A JP62156201A JP15620187A JPS643125A JP S643125 A JPS643125 A JP S643125A JP 62156201 A JP62156201 A JP 62156201A JP 15620187 A JP15620187 A JP 15620187A JP S643125 A JPS643125 A JP S643125A
Authority
JP
Japan
Prior art keywords
fructus
leaves
rumulus
zanthoxylum
inhibitor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP62156201A
Other languages
Japanese (ja)
Other versions
JPH013125A (en
JP2548941B2 (en
Inventor
Hiroyuki Kojima
Yutaka Ando
Kenji Matsui
Makoto Tsuboi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ichimaru Pharcos Co Ltd
Original Assignee
Ichimaru Pharcos Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ichimaru Pharcos Co Ltd filed Critical Ichimaru Pharcos Co Ltd
Priority to JP62156201A priority Critical patent/JP2548941B2/en
Publication of JPS643125A publication Critical patent/JPS643125A/en
Publication of JPH013125A publication Critical patent/JPH013125A/en
Application granted granted Critical
Publication of JP2548941B2 publication Critical patent/JP2548941B2/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q7/00—Preparations for affecting hair growth
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783—Angiosperms [Magnoliophyta]
    • A61K8/9789—Magnoliopsida [dicotyledons]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/74—Biological properties of particular ingredients
    • A61K2800/78—Enzyme modulators, e.g. Enzyme agonists
    • A61K2800/782—Enzyme inhibitors; Enzyme antagonists

Abstract

PURPOSE:To obtain testron 5alpha-reductase inhibitor containing extract of crude drug obtained from either one of Polygoni Multiflori Radix, Chaenomelis Fructus, Zanthoxylic Fructus and Thujae Orientalis Folium Et Rumulus and useful in remedy for android baldness and coarse hair disease. CONSTITUTION:An extract of crude drug from either one of Polygoni Multiflori radix obtained by drying lump root of Polygonum multiflorum Thunb. of Polygonaceae, Chaenomelis Fructus obtained by transversely or longitudinally cutting ripe fruit of flowering quince of Rosaceae, Zanthoxyli Fructus obtained from seed of Zanthoxylum of Ructaceae and plant belonging to same genus as the Zanthoxylum and Thujae Orientalis Folium Et Rumulus obtained by drying branch having leaves of Thuja orientalis L. of Cupressaceae or leaves or leaves having young branch of Shrubby yew of Podocarpaceae is contained. The above-mentioned inhibitor is used for formulation of medicine, quasi-drug or cosmetics as form for internal or external use. The inhibitor suppress dihydrotestrone produced by reduction of testosterone which is main ingredient of androgen and capable of enhancing depilation and tallow secreting ability.
JP62156201A 1987-06-23 1987-06-23 Testosterone 5α-reductase inhibitor Expired - Lifetime JP2548941B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP62156201A JP2548941B2 (en) 1987-06-23 1987-06-23 Testosterone 5α-reductase inhibitor

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP62156201A JP2548941B2 (en) 1987-06-23 1987-06-23 Testosterone 5α-reductase inhibitor

Publications (3)

Publication Number Publication Date
JPS643125A true JPS643125A (en) 1989-01-06
JPH013125A JPH013125A (en) 1989-01-06
JP2548941B2 JP2548941B2 (en) 1996-10-30

Family

ID=15622576

Family Applications (1)

Application Number Title Priority Date Filing Date
JP62156201A Expired - Lifetime JP2548941B2 (en) 1987-06-23 1987-06-23 Testosterone 5α-reductase inhibitor

Country Status (1)

Country Link
JP (1) JP2548941B2 (en)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0248517A (en) * 1988-08-11 1990-02-19 Shiseido Co Ltd Hair tonic
JPH04173720A (en) * 1990-11-05 1992-06-22 Sankyo Co Ltd Hair growth agent
EP0747048A2 (en) * 1995-06-09 1996-12-11 Kabushiki Kaisha Yakurigaku Chuo Kenkyusho Diterpenes and flavonoids as 5-alpha-reductase inhibitors
JP2006083084A (en) * 2004-09-15 2006-03-30 Maruzen Pharmaceut Co Ltd Hair-growing agent and scalp cosmetic
JP2013032331A (en) * 2011-07-06 2013-02-14 Kose Corp Lipid production-inhibiting agent, sebum production-inhibiting agent, and triacylglycerol production-inhibiting agent

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4320941Y1 (en) * 1964-09-26 1968-09-03
JPS4851732U (en) * 1971-10-19 1973-07-05

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4320941Y1 (en) * 1964-09-26 1968-09-03
JPS4851732U (en) * 1971-10-19 1973-07-05

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0248517A (en) * 1988-08-11 1990-02-19 Shiseido Co Ltd Hair tonic
JPH04173720A (en) * 1990-11-05 1992-06-22 Sankyo Co Ltd Hair growth agent
EP0747048A2 (en) * 1995-06-09 1996-12-11 Kabushiki Kaisha Yakurigaku Chuo Kenkyusho Diterpenes and flavonoids as 5-alpha-reductase inhibitors
EP0747048A3 (en) * 1995-06-09 1998-04-15 Kabushiki Kaisha Yakurigaku Chuo Kenkyusho Diterpenes and flavonoids as 5-alpha-reductase inhibitors
US5773005A (en) * 1995-06-09 1998-06-30 Takahashi; Hidehiko Purified flavonoid and diterpene 5α-reductase inhibitors from thuja orientalis for androgen-related diseases
JP2006083084A (en) * 2004-09-15 2006-03-30 Maruzen Pharmaceut Co Ltd Hair-growing agent and scalp cosmetic
JP2013032331A (en) * 2011-07-06 2013-02-14 Kose Corp Lipid production-inhibiting agent, sebum production-inhibiting agent, and triacylglycerol production-inhibiting agent

Also Published As

Publication number Publication date
JP2548941B2 (en) 1996-10-30

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